Full name : Grady Sharon R
First name : Sharon R
Mail : Institute for Behavioral Genetics, University of Colorado, 447UCB, Boulder, CO 80409
Zip Code :
City :
Country : USA
Email : sharon.grady@colorado.edu
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Comment
Title : Effectiveness of Nicotinic Agonists as Desensitizers at Presynaptic alpha4beta2- and alpha4alpha5beta2-Nicotinic Acetylcholine Receptors - Wageman_2014_Nicotine.Tob.Res_16_297 |
Author(s) : Wageman CR , Marks MJ , Grady SR |
Ref : Nicotine Tob Res , 16 :297 , 2014 |
Abstract : |
PubMedSearch : Wageman_2014_Nicotine.Tob.Res_16_297 |
PubMedID: 24052501 |
Title : Multiple CNS nicotinic receptors mediate L-dopa-induced dyskinesias: studies with parkinsonian nicotinic receptor knockout mice - Quik_2013_Biochem.Pharmacol_86(8)_1153 |
Author(s) : Quik M , Campos C , Grady SR |
Ref : Biochemical Pharmacology , 86 :1153 , 2013 |
Abstract : |
PubMedSearch : Quik_2013_Biochem.Pharmacol_86(8)_1153 |
PubMedID: 23831952 |
Title : Exploring the nicotinic acetylcholine receptor-associated proteome with iTRAQ and transgenic mice - McClure-Begley_2013_Genomics.Proteomics.Bioinformatics_11_207 |
Author(s) : McClure-Begley TD , Stone KL , Marks MJ , Grady SR , Colangelo CM , Lindstrom JM , Picciotto MR |
Ref : Genomics Proteomics Bioinformatics , 11 :207 , 2013 |
Abstract : |
PubMedSearch : McClure-Begley_2013_Genomics.Proteomics.Bioinformatics_11_207 |
PubMedID: 23891776 |
Title : CC4, a dimer of cytisine, is a selective partial agonist at alpha4beta2\/alpha6beta2 nAChR with improved selectivity for tobacco smoking cessation - Sala_2013_Br.J.Pharmacol_168_835 |
Author(s) : Sala M , Braida D , Pucci L , Manfredi I , Marks MJ , Wageman CR , Grady SR , Loi B , Fucile S , Fasoli F , Zoli M , Tasso B , Sparatore F , Clementi F , Gotti C |
Ref : British Journal of Pharmacology , 168 :835 , 2013 |
Abstract : |
PubMedSearch : Sala_2013_Br.J.Pharmacol_168_835 |
PubMedID: 22957729 |
Title : Mice expressing the ADNFLE valine 287 leucine mutation of the Beta2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function - O'Neill_2013_Pharmacol.Biochem.Behav_103_603 |
Author(s) : O'Neill HC , Laverty DC , Patzlaff NE , Cohen BN , Fonck C , McKinney S , McIntosh JM , Lindstrom JM , Lester HA , Grady SR , Marks MJ |
Ref : Pharmacol Biochem Behav , 103 :603 , 2013 |
Abstract : |
PubMedSearch : O'Neill_2013_Pharmacol.Biochem.Behav_103_603 |
PubMedID: 23123803 |
Title : A role for alpha4(non-alpha6)* nicotinic acetylcholine receptors in motor behavior - Soll_2013_Neuropharmacol_73_19 |
Author(s) : Soll LG , Grady SR , Salminen O , Marks MJ , Tapper AR |
Ref : Neuropharmacology , 73 :19 , 2013 |
Abstract : |
PubMedSearch : Soll_2013_Neuropharmacol_73_19 |
PubMedID: 23688922 |
Title : Nicotinic cholinergic mechanisms causing elevated dopamine release and abnormal locomotor behavior - Cohen_2012_Neurosci_200_31 |
Author(s) : Cohen BN , Mackey ED , Grady SR , McKinney S , Patzlaff NE , Wageman CR , McIntosh JM , Marks MJ , Lester HA , Drenan RM |
Ref : Neuroscience , 200 :31 , 2012 |
Abstract : |
PubMedSearch : Cohen_2012_Neurosci_200_31 |
PubMedID: 22079576 |
Title : alpha6* nicotinic acetylcholine receptor expression and function in a visual salience circuit - Mackey_2012_J.Neurosci_32_10226 |
Author(s) : Mackey ED , Engle SE , Kim MR , O'Neill HC , Wageman CR , Patzlaff NE , Wang Y , Grady SR , McIntosh JM , Marks MJ , Lester HA , Drenan RM |
Ref : Journal of Neuroscience , 32 :10226 , 2012 |
Abstract : |
PubMedSearch : Mackey_2012_J.Neurosci_32_10226 |
PubMedID: 22836257 |
Title : Role for alpha6 nicotinic receptors in l-dopa-induced dyskinesias in parkinsonian mice - Quik_2012_Neuropharmacol_63_450 |
Author(s) : Quik M , Park KM , Hrachova M , Mallela A , Huang LZ , McIntosh JM , Grady SR |
Ref : Neuropharmacology , 63 :450 , 2012 |
Abstract : |
PubMedSearch : Quik_2012_Neuropharmacol_63_450 |
PubMedID: 22579614 |
Title : Nicotine-mediated activation of dopaminergic neurons in distinct regions of the ventral tegmental area - Zhao-Shea_2011_Neuropsychopharmacology_36_1021 |
Author(s) : Zhao-Shea R , Liu L , Soll LG , Improgo MR , Meyers EE , McIntosh JM , Grady SR , Marks MJ , Gardner PD , Tapper AR |
Ref : Neuropsychopharmacology , 36 :1021 , 2011 |
Abstract : |
PubMedSearch : Zhao-Shea_2011_Neuropsychopharmacology_36_1021 |
PubMedID: 21289604 |
Title : Role of alpha6 nicotinic receptors in CNS dopaminergic function: relevance to addiction and neurological disorders - Quik_2011_Biochem.Pharmacol_82(8)_873 |
Author(s) : Quik M , Perez XA , Grady SR |
Ref : Biochemical Pharmacology , 82 :873 , 2011 |
Abstract : |
PubMedSearch : Quik_2011_Biochem.Pharmacol_82(8)_873 |
PubMedID: 21684266 |
Title : alpha4beta2 nicotinic acetylcholine receptors on dopaminergic neurons mediate nicotine reward and anxiety relief - McGranahan_2011_J.Neurosci_31_10891 |
Author(s) : McGranahan TM , Patzlaff NE , Grady SR , Heinemann SF , Booker TK |
Ref : Journal of Neuroscience , 31 :10891 , 2011 |
Abstract : |
PubMedSearch : McGranahan_2011_J.Neurosci_31_10891 |
PubMedID: 21795541 |
Title : Nicotine reduces L-DOPA-induced dyskinesias by acting at beta2* nicotinic receptors - Huang_2011_J.Pharmacol.Exp.Ther_338_932 |
Author(s) : Huang LZ , Grady SR , Quik M |
Ref : Journal of Pharmacology & Experimental Therapeutics , 338 :932 , 2011 |
Abstract : |
PubMedSearch : Huang_2011_J.Pharmacol.Exp.Ther_338_932 |
PubMedID: 21665941 |
Title : Poster: Comparison of binding and functional activity profiles for a set of nicotinic acetylcholine receptor ligands across multiple alpha6* expression systems - |
Author(s) : Breining SR , Hepler C , Whiteaker P , Quik M , Grady SR , Yohannes D |
Ref : Biochemical Pharmacology , 82 :1024 , 2011 |
PubMedID: |
Title : Poster: alpha6* nAChR expression and function in brain areas influencing DA transmission probed with alpha6-GFP transgenic mice - |
Author(s) : Drenan RM , Mackey EDW , Grady SR , Patzlaff NE , Wageman CR , McIntosh JM , Marks MJ , Lester HA |
Ref : Biochemical Pharmacology , 82 :1035 , 2011 |
PubMedID: |
Title : Dopamine D2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive {alpha}4 nicotinic receptors via a cholinergic-dependent mechanism - Zhao-Shea_2010_FASEB.J_24_49 |
Author(s) : Zhao-Shea R , Cohen BN , Just H , McClure-Begley TD , Whiteaker P , Grady SR , Salminen O , Gardner PD , Lester HA , Tapper AR |
Ref : FASEB Journal , 24 :49 , 2010 |
Abstract : |
PubMedSearch : Zhao-Shea_2010_FASEB.J_24_49 |
PubMedID: 19720621 |
Title : Mouse striatal dopamine nerve terminals express alpha4alpha5beta2 and two stoichiometric forms of alpha4beta2*-nicotinic acetylcholine receptors - Grady_2010_J.Mol.Neurosci_40_91 |
Author(s) : Grady SR , Salminen O , McIntosh JM , Marks MJ , Collins AC |
Ref : Journal of Molecular Neuroscience , 40 :91 , 2010 |
Abstract : |
PubMedSearch : Grady_2010_J.Mol.Neurosci_40_91 |
PubMedID: 19693710 |
Title : John Daly's compound, epibatidine, facilitates identification of nicotinic receptor subtypes - Marks_2010_J.Mol.Neurosci_40_96 |
Author(s) : Marks MJ , Laverty DS , Whiteaker P , Salminen O , Grady SR , McIntosh JM , Collins AC |
Ref : Journal of Molecular Neuroscience , 40 :96 , 2010 |
Abstract : |
PubMedSearch : Marks_2010_J.Mol.Neurosci_40_96 |
PubMedID: 19672723 |
Title : Structural differences determine the relative selectivity of nicotinic compounds for native alpha 4 beta 2*-, alpha 6 beta 2*-, alpha 3 beta 4*- and alpha 7-nicotine acetylcholine receptors - Grady_2010_Neuropharmacol_58_1054 |
Author(s) : Grady SR , Drenan RM , Breining SR , Yohannes D , Wageman CR , Fedorov NB , McKinney S , Whiteaker P , Bencherif M , Lester HA , Marks MJ |
Ref : Neuropharmacology , 58 :1054 , 2010 |
Abstract : |
PubMedSearch : Grady_2010_Neuropharmacol_58_1054 |
PubMedID: 20114055 |
Title : Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors - Drenan_2010_J.Neurosci_30_9877 |
Author(s) : Drenan RM , Grady SR , Steele AD , McKinney S , Patzlaff NE , McIntosh JM , Marks MJ , Miwa JM , Lester HA |
Ref : Journal of Neuroscience , 30 :9877 , 2010 |
Abstract : |
PubMedSearch : Drenan_2010_J.Neurosci_30_9877 |
PubMedID: 20660270 |
Title : Localized low-level re-expression of high-affinity mesolimbic nicotinic acetylcholine receptors restores nicotine-induced locomotion but not place conditioning - Mineur_2009_Genes.Brain.Behav_8_257 |
Author(s) : Mineur YS , Brunzell DH , Grady SR , Lindstrom JM , McIntosh JM , Marks MJ , King SL , Picciotto MR |
Ref : Genes Brain Behav , 8 :257 , 2009 |
Abstract : |
PubMedSearch : Mineur_2009_Genes.Brain.Behav_8_257 |
PubMedID: 19077117 |
Title : Poster: Selectivity of ABT-089 for alpha4\/beta2* and alpha6\/beta2 nicotinic acetylcholine receptors in brain - |
Author(s) : Marks MJ , Wageman CR , Grady SR , Gopalakrishnan M , Briggs CA |
Ref : Biochemical Pharmacology , 78 :910 , 2009 |
PubMedID: |
Title : Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the alpha6( *) subtype - Breining_2009_Bioorg.Med.Chem.Lett_19_4359 |
Author(s) : Breining SR , Bencherif M , Grady SR , Whiteaker P , Marks MJ , Wageman CR , Lester HA , Yohannes D |
Ref : Bioorganic & Medicinal Chemistry Lett , 19 :4359 , 2009 |
Abstract : |
PubMedSearch : Breining_2009_Bioorg.Med.Chem.Lett_19_4359 |
PubMedID: 19560354 |
Title : Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the alpha3beta4* and alpha3beta3beta4* subtypes mediate acetylcholine release - Grady_2009_J.Neurosci_29_2272 |
Author(s) : Grady SR , Moretti M , Zoli M , Marks MJ , Zanardi A , Pucci L , Clementi F , Gotti C |
Ref : Journal of Neuroscience , 29 :2272 , 2009 |
Abstract : |
PubMedSearch : Grady_2009_J.Neurosci_29_2272 |
PubMedID: 19228980 |
Title : Selectivity of ABT-089 for alpha4beta2* and alpha6beta2* nicotinic acetylcholine receptors in brain - Marks_2009_Biochem.Pharmacol_78(7)_795 |
Author(s) : Marks MJ , Wageman CR , Grady SR , Gopalakrishnan M , Briggs CA |
Ref : Biochemical Pharmacology , 78 :795 , 2009 |
Abstract : |
PubMedSearch : Marks_2009_Biochem.Pharmacol_78(7)_795 |
PubMedID: 19481067 |
Title : In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors - Drenan_2008_Neuron_60_123 |
Author(s) : Drenan RM , Grady SR , Whiteaker P , McClure-Begley TD , McKinney S , Miwa JM , Bupp S , Heintz N , McIntosh JM , Bencherif M , Marks MJ , Lester HA |
Ref : Neuron , 60 :123 , 2008 |
Abstract : |
PubMedSearch : Drenan_2008_Neuron_60_123 |
PubMedID: 18940593 |
Title : Guidelines on nicotine dose selection for in vivo research - Matta_2007_Psychopharmacology.(Berl)_190_269 |
Author(s) : Matta SG , Balfour DJ , Benowitz NL , Boyd RT , Buccafusco JJ , Caggiula AR , Craig CR , Collins AC , Damaj MI , Donny EC , Gardiner PS , Grady SR , Heberlein U , Leonard SS , Levin ED , Lukas RJ , Markou A , Marks MJ , McCallum SE , Parameswaran N , Perkins KA , Picciotto MR , Quik M , Rose JE , Rothenfluh A , Schafer WR , Stolerman IP , Tyndale RF , Wehner JM , Zirger JM |
Ref : Psychopharmacology (Berl) , 190 :269 , 2007 |
Abstract : |
PubMedSearch : Matta_2007_Psychopharmacology.(Berl)_190_269 |
PubMedID: 16896961 |
Title : Nigrostriatal damage preferentially decreases a subpopulation of alpha6beta2* nAChRs in mouse, monkey, and Parkinson's disease striatum - Bordia_2007_Mol.Pharmacol_72_52 |
Author(s) : Bordia T , Grady SR , McIntosh JM , Quik M |
Ref : Molecular Pharmacology , 72 :52 , 2007 |
Abstract : |
PubMedSearch : Bordia_2007_Mol.Pharmacol_72_52 |
PubMedID: 17409284 |
Title : Nicotine-induced dystonic arousal complex in a mouse line harboring a human autosomal-dominant nocturnal frontal lobe epilepsy mutation - Teper_2007_J.Neurosci_27_10128 |
Author(s) : Teper Y , Whyte D , Cahir E , Lester HA , Grady SR , Marks MJ , Cohen BN , Fonck C , McClure-Begley TD , McIntosh JM , Labarca C , Lawrence A , Chen F , Gantois I , Davies PJ , Petrou S , Murphy M , Waddington J , Horne MK , Berkovic SF , Drago J |
Ref : Journal of Neuroscience , 27 :10128 , 2007 |
Abstract : |
PubMedSearch : Teper_2007_J.Neurosci_27_10128 |
PubMedID: 17881519 |
Title : The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum - Grady_2007_Biochem.Pharmacol_74(8)_1235 |
Author(s) : Grady SR , Salminen O , Laverty DC , Whiteaker P , McIntosh JM , Collins AC , Marks MJ |
Ref : Biochemical Pharmacology , 74 :1235 , 2007 |
Abstract : |
PubMedSearch : Grady_2007_Biochem.Pharmacol_74(8)_1235 |
PubMedID: 17825262 |
Title : Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path - Nashmi_2007_J.Neurosci_27_8202 |
Author(s) : Nashmi R , Xiao C , Deshpande P , McKinney S , Grady SR , Whiteaker P , Huang Q , McClure-Begley TD , Lindstrom JM , Labarca C , Collins AC , Marks MJ , Lester HA |
Ref : Journal of Neuroscience , 27 :8202 , 2007 |
Abstract : |
PubMedSearch : Nashmi_2007_J.Neurosci_27_8202 |
PubMedID: 17670967 |
Title : Decrease in alpha3*\/alpha6* nicotinic receptors but not nicotine-evoked dopamine release in monkey brain after nigrostriatal damage - McCallum_2005_Mol.Pharmacol_68_737 |
Author(s) : McCallum SE , Parameswaran N , Bordia T , McIntosh JM , Grady SR , Quik M |
Ref : Molecular Pharmacology , 68 :737 , 2005 |
Abstract : |
PubMedSearch : McCallum_2005_Mol.Pharmacol_68_737 |
PubMedID: 15933214 |
Title : Long-term nicotine treatment decreases striatal alpha 6* nicotinic acetylcholine receptor sites and function in mice - Lai_2005_Mol.Pharmacol_67_1639 |
Author(s) : Lai A , Parameswaran N , Khwaja M , Whiteaker P , Lindstrom JM , Fan H , McIntosh JM , Grady SR , Quik M |
Ref : Molecular Pharmacology , 67 :1639 , 2005 |
Abstract : |
PubMedSearch : Lai_2005_Mol.Pharmacol_67_1639 |
PubMedID: 15681595 |
Title : Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice - Salminen_2004_Mol.Pharmacol_65_1526 |
Author(s) : Salminen O , Murphy KL , McIntosh JM , Drago J , Marks MJ , Collins AC , Grady SR |
Ref : Molecular Pharmacology , 65 :1526 , 2004 |
Abstract : |
PubMedSearch : Salminen_2004_Mol.Pharmacol_65_1526 |
PubMedID: 15155845 |
Title : The beta3 nicotinic receptor subunit: a component of alpha-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors - Cui_2003_J.Neurosci_23_11045 |
Author(s) : Cui C , Booker TK , Allen RS , Grady SR , Whiteaker P , Marks MJ , Salminen O , Tritto T , Butt CM , Allen WR , Stitzel JA , McIntosh JM , Boulter J , Collins AC , Heinemann SF |
Ref : Journal of Neuroscience , 23 :11045 , 2003 |
Abstract : |
PubMedSearch : Cui_2003_J.Neurosci_23_11045 |
PubMedID: 14657161 |
Title : Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior - King_2003_J.Neurosci_23_3837 |
Author(s) : King SL , Marks MJ , Grady SR , Caldarone BJ , Koren AO , Mukhin AG , Collins AC , Picciotto MR |
Ref : Journal of Neuroscience , 23 :3837 , 2003 |
Abstract : |
PubMedSearch : King_2003_J.Neurosci_23_3837 |
PubMedID: 12736354 |
Title : Characterization of [(125) I]epibatidine binding and nicotinic agonist-mediated (86) Rb(+) efflux in interpeduncular nucleus and inferior colliculus of beta2 null mutant mice - Marks_2002_J.Neurochem_81_1102 |
Author(s) : Marks MJ , Whiteaker P , Grady SR , Picciotto MR , McIntosh JM , Collins AC |
Ref : Journal of Neurochemistry , 81 :1102 , 2002 |
Abstract : |
PubMedSearch : Marks_2002_J.Neurochem_81_1102 |
PubMedID: 12065623 |
Title : Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: a function mediated by a different nAChR than dopamine release from striatum - Grady_2001_J.Neurochem_76_258 |
Author(s) : Grady SR , Meinerz NM , Cao J , Reynolds AM , Picciotto MR , Changeux JP , McIntosh JM , Marks MJ , Collins AC |
Ref : Journal of Neurochemistry , 76 :258 , 2001 |
Abstract : |
PubMedSearch : Grady_2001_J.Neurochem_76_258 |
PubMedID: 11145999 |
Title : Nicotinic-agonist stimulated (86)Rb(+) efflux and [(3)H]epibatidine binding of mice differing in beta2 genotype - Marks_2000_Neuropharmacol_39_2632 |
Author(s) : Marks MJ , Stitzel JA , Grady SR , Picciotto MR , Changeux JP , Collins AC |
Ref : Neuropharmacology , 39 :2632 , 2000 |
Abstract : |
PubMedSearch : Marks_2000_Neuropharmacol_39_2632 |
PubMedID: 11044733 |
Title : Pharmacological and null mutation approaches reveal nicotinic receptor diversity - Whiteaker_2000_Eur.J.Pharmacol_393_123 |
Author(s) : Whiteaker P , Marks MJ , Grady SR , Lu Y , Picciotto MR , Changeux JP , Collins AC |
Ref : European Journal of Pharmacology , 393 :123 , 2000 |
Abstract : |
PubMedSearch : Whiteaker_2000_Eur.J.Pharmacol_393_123 |
PubMedID: 10771005 |
Title : International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits - |
Author(s) : Lukas RJ , Changeux JP , Le Novere N , Albuquerque EX , Balfour DJ , Berg DK , Bertrand D , Chiappinelli VA , Clarke PB , Collins AC , Dani JA , Grady SR , Kellar KJ , Lindstrom JM , Marks MJ , Quik M , Taylor P , Wonnacott S |
Ref : Pharmacol Rev , 51 :397 , 1999 |
PubMedID: 10353988 |
Title : Two pharmacologically distinct components of nicotinic receptor-mediated rubidium efflux in mouse brain require the beta2 subunit - Marks_1999_J.Pharmacol.Exp.Ther_289_1090 |
Author(s) : Marks MJ , Whiteaker P , Calcaterra J , Stitzel JA , Bullock AE , Grady SR , Picciotto MR , Changeux JP , Collins AC |
Ref : Journal of Pharmacology & Experimental Therapeutics , 289 :1090 , 1999 |
Abstract : |
PubMedSearch : Marks_1999_J.Pharmacol.Exp.Ther_289_1090 |
PubMedID: 10215692 |