Grady SR

General

Full name : Grady Sharon R

First name : Sharon R

Mail : Institute for Behavioral Genetics, University of Colorado, 447UCB, Boulder, CO 80409

Zip Code :

City :

Country : USA

Email : sharon.grady@colorado.edu

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References (42)

Title : Effectiveness of Nicotinic Agonists as Desensitizers at Presynaptic alpha4beta2- and alpha4alpha5beta2-Nicotinic Acetylcholine Receptors - Wageman_2014_Nicotine.Tob.Res_16_297
Author(s) : Wageman CR , Marks MJ , Grady SR
Ref : Nicotine Tob Res , 16 :297 , 2014
Abstract :
PubMedSearch : Wageman_2014_Nicotine.Tob.Res_16_297
PubMedID: 24052501

Title : A role for alpha4(non-alpha6)* nicotinic acetylcholine receptors in motor behavior - Soll_2013_Neuropharmacol_73_19
Author(s) : Soll LG , Grady SR , Salminen O , Marks MJ , Tapper AR
Ref : Neuropharmacology , 73 :19 , 2013
Abstract :
PubMedSearch : Soll_2013_Neuropharmacol_73_19
PubMedID: 23688922

Title : Exploring the nicotinic acetylcholine receptor-associated proteome with iTRAQ and transgenic mice - McClure-Begley_2013_Genomics.Proteomics.Bioinformatics_11_207
Author(s) : McClure-Begley TD , Stone KL , Marks MJ , Grady SR , Colangelo CM , Lindstrom JM , Picciotto MR
Ref : Genomics Proteomics Bioinformatics , 11 :207 , 2013
Abstract :
PubMedSearch : McClure-Begley_2013_Genomics.Proteomics.Bioinformatics_11_207
PubMedID: 23891776

Title : CC4, a dimer of cytisine, is a selective partial agonist at alpha4beta2\/alpha6beta2 nAChR with improved selectivity for tobacco smoking cessation - Sala_2013_Br.J.Pharmacol_168_835
Author(s) : Sala M , Braida D , Pucci L , Manfredi I , Marks MJ , Wageman CR , Grady SR , Loi B , Fucile S , Fasoli F , Zoli M , Tasso B , Sparatore F , Clementi F , Gotti C
Ref : British Journal of Pharmacology , 168 :835 , 2013
Abstract :
PubMedSearch : Sala_2013_Br.J.Pharmacol_168_835
PubMedID: 22957729

Title : Mice expressing the ADNFLE valine 287 leucine mutation of the Beta2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function - O'Neill_2013_Pharmacol.Biochem.Behav_103_603
Author(s) : O'Neill HC , Laverty DC , Patzlaff NE , Cohen BN , Fonck C , McKinney S , McIntosh JM , Lindstrom JM , Lester HA , Grady SR , Marks MJ
Ref : Pharmacol Biochem Behav , 103 :603 , 2013
Abstract :
PubMedSearch : O'Neill_2013_Pharmacol.Biochem.Behav_103_603
PubMedID: 23123803

Title : Multiple CNS nicotinic receptors mediate L-dopa-induced dyskinesias: studies with parkinsonian nicotinic receptor knockout mice - Quik_2013_Biochem.Pharmacol_86(8)_1153
Author(s) : Quik M , Campos C , Grady SR
Ref : Biochemical Pharmacology , 86 :1153 , 2013
Abstract :
PubMedSearch : Quik_2013_Biochem.Pharmacol_86(8)_1153
PubMedID: 23831952

Title : Role for alpha6 nicotinic receptors in l-dopa-induced dyskinesias in parkinsonian mice - Quik_2012_Neuropharmacol_63_450
Author(s) : Quik M , Park KM , Hrachova M , Mallela A , Huang LZ , McIntosh JM , Grady SR
Ref : Neuropharmacology , 63 :450 , 2012
Abstract :
PubMedSearch : Quik_2012_Neuropharmacol_63_450
PubMedID: 22579614

Title : Nicotinic cholinergic mechanisms causing elevated dopamine release and abnormal locomotor behavior - Cohen_2012_Neurosci_200_31
Author(s) : Cohen BN , Mackey ED , Grady SR , McKinney S , Patzlaff NE , Wageman CR , McIntosh JM , Marks MJ , Lester HA , Drenan RM
Ref : Neuroscience , 200 :31 , 2012
Abstract :
PubMedSearch : Cohen_2012_Neurosci_200_31
PubMedID: 22079576

Title : alpha6* nicotinic acetylcholine receptor expression and function in a visual salience circuit - Mackey_2012_J.Neurosci_32_10226
Author(s) : Mackey ED , Engle SE , Kim MR , O'Neill HC , Wageman CR , Patzlaff NE , Wang Y , Grady SR , McIntosh JM , Marks MJ , Lester HA , Drenan RM
Ref : Journal of Neuroscience , 32 :10226 , 2012
Abstract :
PubMedSearch : Mackey_2012_J.Neurosci_32_10226
PubMedID: 22836257

Title : Poster: Comparison of binding and functional activity profiles for a set of nicotinic acetylcholine receptor ligands across multiple alpha6* expression systems -
Author(s) : Breining SR , Hepler C , Whiteaker P , Quik M , Grady SR , Yohannes D
Ref : Biochemical Pharmacology , 82 :1024 , 2011
PubMedID:

Title : Poster: alpha6* nAChR expression and function in brain areas influencing DA transmission probed with alpha6-GFP transgenic mice -
Author(s) : Drenan RM , Mackey EDW , Grady SR , Patzlaff NE , Wageman CR , McIntosh JM , Marks MJ , Lester HA
Ref : Biochemical Pharmacology , 82 :1035 , 2011
PubMedID:

Title : Nicotine-mediated activation of dopaminergic neurons in distinct regions of the ventral tegmental area - Zhao-Shea_2011_Neuropsychopharmacology_36_1021
Author(s) : Zhao-Shea R , Liu L , Soll LG , Improgo MR , Meyers EE , McIntosh JM , Grady SR , Marks MJ , Gardner PD , Tapper AR
Ref : Neuropsychopharmacology , 36 :1021 , 2011
Abstract :
PubMedSearch : Zhao-Shea_2011_Neuropsychopharmacology_36_1021
PubMedID: 21289604

Title : alpha4beta2 nicotinic acetylcholine receptors on dopaminergic neurons mediate nicotine reward and anxiety relief - McGranahan_2011_J.Neurosci_31_10891
Author(s) : McGranahan TM , Patzlaff NE , Grady SR , Heinemann SF , Booker TK
Ref : Journal of Neuroscience , 31 :10891 , 2011
Abstract :
PubMedSearch : McGranahan_2011_J.Neurosci_31_10891
PubMedID: 21795541

Title : Nicotine reduces L-DOPA-induced dyskinesias by acting at beta2* nicotinic receptors - Huang_2011_J.Pharmacol.Exp.Ther_338_932
Author(s) : Huang LZ , Grady SR , Quik M
Ref : Journal of Pharmacology & Experimental Therapeutics , 338 :932 , 2011
Abstract :
PubMedSearch : Huang_2011_J.Pharmacol.Exp.Ther_338_932
PubMedID: 21665941

Title : Role of alpha6 nicotinic receptors in CNS dopaminergic function: relevance to addiction and neurological disorders - Quik_2011_Biochem.Pharmacol_82(8)_873
Author(s) : Quik M , Perez XA , Grady SR
Ref : Biochemical Pharmacology , 82 :873 , 2011
Abstract :
PubMedSearch : Quik_2011_Biochem.Pharmacol_82(8)_873
PubMedID: 21684266

Title : Dopamine D2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive {alpha}4 nicotinic receptors via a cholinergic-dependent mechanism - Zhao-Shea_2010_FASEB.J_24_49
Author(s) : Zhao-Shea R , Cohen BN , Just H , McClure-Begley TD , Whiteaker P , Grady SR , Salminen O , Gardner PD , Lester HA , Tapper AR
Ref : FASEB Journal , 24 :49 , 2010
Abstract :
PubMedSearch : Zhao-Shea_2010_FASEB.J_24_49
PubMedID: 19720621

Title : Mouse striatal dopamine nerve terminals express alpha4alpha5beta2 and two stoichiometric forms of alpha4beta2*-nicotinic acetylcholine receptors - Grady_2010_J.Mol.Neurosci_40_91
Author(s) : Grady SR , Salminen O , McIntosh JM , Marks MJ , Collins AC
Ref : Journal of Molecular Neuroscience , 40 :91 , 2010
Abstract :
PubMedSearch : Grady_2010_J.Mol.Neurosci_40_91
PubMedID: 19693710

Title : John Daly's compound, epibatidine, facilitates identification of nicotinic receptor subtypes - Marks_2010_J.Mol.Neurosci_40_96
Author(s) : Marks MJ , Laverty DS , Whiteaker P , Salminen O , Grady SR , McIntosh JM , Collins AC
Ref : Journal of Molecular Neuroscience , 40 :96 , 2010
Abstract :
PubMedSearch : Marks_2010_J.Mol.Neurosci_40_96
PubMedID: 19672723

Title : Structural differences determine the relative selectivity of nicotinic compounds for native alpha 4 beta 2*-, alpha 6 beta 2*-, alpha 3 beta 4*- and alpha 7-nicotine acetylcholine receptors - Grady_2010_Neuropharmacol_58_1054
Author(s) : Grady SR , Drenan RM , Breining SR , Yohannes D , Wageman CR , Fedorov NB , McKinney S , Whiteaker P , Bencherif M , Lester HA , Marks MJ
Ref : Neuropharmacology , 58 :1054 , 2010
Abstract :
PubMedSearch : Grady_2010_Neuropharmacol_58_1054
PubMedID: 20114055

Title : Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors - Drenan_2010_J.Neurosci_30_9877
Author(s) : Drenan RM , Grady SR , Steele AD , McKinney S , Patzlaff NE , McIntosh JM , Marks MJ , Miwa JM , Lester HA
Ref : Journal of Neuroscience , 30 :9877 , 2010
Abstract :
PubMedSearch : Drenan_2010_J.Neurosci_30_9877
PubMedID: 20660270

Title : Poster: Selectivity of ABT-089 for alpha4\/beta2* and alpha6\/beta2 nicotinic acetylcholine receptors in brain -
Author(s) : Marks MJ , Wageman CR , Grady SR , Gopalakrishnan M , Briggs CA
Ref : Biochemical Pharmacology , 78 :910 , 2009
PubMedID:

Title : Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the alpha3beta4* and alpha3beta3beta4* subtypes mediate acetylcholine release - Grady_2009_J.Neurosci_29_2272
Author(s) : Grady SR , Moretti M , Zoli M , Marks MJ , Zanardi A , Pucci L , Clementi F , Gotti C
Ref : Journal of Neuroscience , 29 :2272 , 2009
Abstract :
PubMedSearch : Grady_2009_J.Neurosci_29_2272
PubMedID: 19228980

Title : Selectivity of ABT-089 for alpha4beta2* and alpha6beta2* nicotinic acetylcholine receptors in brain - Marks_2009_Biochem.Pharmacol_78(7)_795
Author(s) : Marks MJ , Wageman CR , Grady SR , Gopalakrishnan M , Briggs CA
Ref : Biochemical Pharmacology , 78 :795 , 2009
Abstract :
PubMedSearch : Marks_2009_Biochem.Pharmacol_78(7)_795
PubMedID: 19481067

Title : Localized low-level re-expression of high-affinity mesolimbic nicotinic acetylcholine receptors restores nicotine-induced locomotion but not place conditioning - Mineur_2009_Genes.Brain.Behav_8_257
Author(s) : Mineur YS , Brunzell DH , Grady SR , Lindstrom JM , McIntosh JM , Marks MJ , King SL , Picciotto MR
Ref : Genes Brain Behav , 8 :257 , 2009
Abstract :
PubMedSearch : Mineur_2009_Genes.Brain.Behav_8_257
PubMedID: 19077117

Title : Evaluation of structurally diverse neuronal nicotinic receptor ligands for selectivity at the alpha6( *) subtype - Breining_2009_Bioorg.Med.Chem.Lett_19_4359
Author(s) : Breining SR , Bencherif M , Grady SR , Whiteaker P , Marks MJ , Wageman CR , Lester HA , Yohannes D
Ref : Bioorganic & Medicinal Chemistry Lett , 19 :4359 , 2009
Abstract :
PubMedSearch : Breining_2009_Bioorg.Med.Chem.Lett_19_4359
PubMedID: 19560354

Title : In vivo activation of midbrain dopamine neurons via sensitized, high-affinity alpha 6 nicotinic acetylcholine receptors - Drenan_2008_Neuron_60_123
Author(s) : Drenan RM , Grady SR , Whiteaker P , McClure-Begley TD , McKinney S , Miwa JM , Bupp S , Heintz N , McIntosh JM , Bencherif M , Marks MJ , Lester HA
Ref : Neuron , 60 :123 , 2008
Abstract :
PubMedSearch : Drenan_2008_Neuron_60_123
PubMedID: 18940593

Title : The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum - Grady_2007_Biochem.Pharmacol_74(8)_1235
Author(s) : Grady SR , Salminen O , Laverty DC , Whiteaker P , McIntosh JM , Collins AC , Marks MJ
Ref : Biochemical Pharmacology , 74 :1235 , 2007
Abstract :
PubMedSearch : Grady_2007_Biochem.Pharmacol_74(8)_1235
PubMedID: 17825262

Title : Nigrostriatal damage preferentially decreases a subpopulation of alpha6beta2* nAChRs in mouse, monkey, and Parkinson's disease striatum - Bordia_2007_Mol.Pharmacol_72_52
Author(s) : Bordia T , Grady SR , McIntosh JM , Quik M
Ref : Molecular Pharmacology , 72 :52 , 2007
Abstract :
PubMedSearch : Bordia_2007_Mol.Pharmacol_72_52
PubMedID: 17409284

Title : Nicotine-induced dystonic arousal complex in a mouse line harboring a human autosomal-dominant nocturnal frontal lobe epilepsy mutation - Teper_2007_J.Neurosci_27_10128
Author(s) : Teper Y , Whyte D , Cahir E , Lester HA , Grady SR , Marks MJ , Cohen BN , Fonck C , McClure-Begley TD , McIntosh JM , Labarca C , Lawrence A , Chen F , Gantois I , Davies PJ , Petrou S , Murphy M , Waddington J , Horne MK , Berkovic SF , Drago J
Ref : Journal of Neuroscience , 27 :10128 , 2007
Abstract :
PubMedSearch : Teper_2007_J.Neurosci_27_10128
PubMedID: 17881519

Title : Guidelines on nicotine dose selection for in vivo research - Matta_2007_Psychopharmacology.(Berl)_190_269
Author(s) : Matta SG , Balfour DJ , Benowitz NL , Boyd RT , Buccafusco JJ , Caggiula AR , Craig CR , Collins AC , Damaj MI , Donny EC , Gardiner PS , Grady SR , Heberlein U , Leonard SS , Levin ED , Lukas RJ , Markou A , Marks MJ , McCallum SE , Parameswaran N , Perkins KA , Picciotto MR , Quik M , Rose JE , Rothenfluh A , Schafer WR , Stolerman IP , Tyndale RF , Wehner JM , Zirger JM
Ref : Psychopharmacology (Berl) , 190 :269 , 2007
Abstract :
PubMedSearch : Matta_2007_Psychopharmacology.(Berl)_190_269
PubMedID: 16896961

Title : Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path - Nashmi_2007_J.Neurosci_27_8202
Author(s) : Nashmi R , Xiao C , Deshpande P , McKinney S , Grady SR , Whiteaker P , Huang Q , McClure-Begley TD , Lindstrom JM , Labarca C , Collins AC , Marks MJ , Lester HA
Ref : Journal of Neuroscience , 27 :8202 , 2007
Abstract :
PubMedSearch : Nashmi_2007_J.Neurosci_27_8202
PubMedID: 17670967

Title : Long-term nicotine treatment decreases striatal alpha 6* nicotinic acetylcholine receptor sites and function in mice - Lai_2005_Mol.Pharmacol_67_1639
Author(s) : Lai A , Parameswaran N , Khwaja M , Whiteaker P , Lindstrom JM , Fan H , McIntosh JM , Grady SR , Quik M
Ref : Molecular Pharmacology , 67 :1639 , 2005
Abstract :
PubMedSearch : Lai_2005_Mol.Pharmacol_67_1639
PubMedID: 15681595

Title : Decrease in alpha3*\/alpha6* nicotinic receptors but not nicotine-evoked dopamine release in monkey brain after nigrostriatal damage - McCallum_2005_Mol.Pharmacol_68_737
Author(s) : McCallum SE , Parameswaran N , Bordia T , McIntosh JM , Grady SR , Quik M
Ref : Molecular Pharmacology , 68 :737 , 2005
Abstract :
PubMedSearch : McCallum_2005_Mol.Pharmacol_68_737
PubMedID: 15933214

Title : Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice - Salminen_2004_Mol.Pharmacol_65_1526
Author(s) : Salminen O , Murphy KL , McIntosh JM , Drago J , Marks MJ , Collins AC , Grady SR
Ref : Molecular Pharmacology , 65 :1526 , 2004
Abstract :
PubMedSearch : Salminen_2004_Mol.Pharmacol_65_1526
PubMedID: 15155845

Title : Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior - King_2003_J.Neurosci_23_3837
Author(s) : King SL , Marks MJ , Grady SR , Caldarone BJ , Koren AO , Mukhin AG , Collins AC , Picciotto MR
Ref : Journal of Neuroscience , 23 :3837 , 2003
Abstract :
PubMedSearch : King_2003_J.Neurosci_23_3837
PubMedID: 12736354

Title : The beta3 nicotinic receptor subunit: a component of alpha-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors - Cui_2003_J.Neurosci_23_11045
Author(s) : Cui C , Booker TK , Allen RS , Grady SR , Whiteaker P , Marks MJ , Salminen O , Tritto T , Butt CM , Allen WR , Stitzel JA , McIntosh JM , Boulter J , Collins AC , Heinemann SF
Ref : Journal of Neuroscience , 23 :11045 , 2003
Abstract :
PubMedSearch : Cui_2003_J.Neurosci_23_11045
PubMedID: 14657161

Title : Characterization of [(125) I]epibatidine binding and nicotinic agonist-mediated (86) Rb(+) efflux in interpeduncular nucleus and inferior colliculus of beta2 null mutant mice - Marks_2002_J.Neurochem_81_1102
Author(s) : Marks MJ , Whiteaker P , Grady SR , Picciotto MR , McIntosh JM , Collins AC
Ref : Journal of Neurochemistry , 81 :1102 , 2002
Abstract :
PubMedSearch : Marks_2002_J.Neurochem_81_1102
PubMedID: 12065623

Title : Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: a function mediated by a different nAChR than dopamine release from striatum - Grady_2001_J.Neurochem_76_258
Author(s) : Grady SR , Meinerz NM , Cao J , Reynolds AM , Picciotto MR , Changeux JP , McIntosh JM , Marks MJ , Collins AC
Ref : Journal of Neurochemistry , 76 :258 , 2001
Abstract :
PubMedSearch : Grady_2001_J.Neurochem_76_258
PubMedID: 11145999

Title : Nicotinic-agonist stimulated (86)Rb(+) efflux and [(3)H]epibatidine binding of mice differing in beta2 genotype - Marks_2000_Neuropharmacol_39_2632
Author(s) : Marks MJ , Stitzel JA , Grady SR , Picciotto MR , Changeux JP , Collins AC
Ref : Neuropharmacology , 39 :2632 , 2000
Abstract :
PubMedSearch : Marks_2000_Neuropharmacol_39_2632
PubMedID: 11044733

Title : Pharmacological and null mutation approaches reveal nicotinic receptor diversity - Whiteaker_2000_Eur.J.Pharmacol_393_123
Author(s) : Whiteaker P , Marks MJ , Grady SR , Lu Y , Picciotto MR , Changeux JP , Collins AC
Ref : European Journal of Pharmacology , 393 :123 , 2000
Abstract :
PubMedSearch : Whiteaker_2000_Eur.J.Pharmacol_393_123
PubMedID: 10771005

Title : International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits -
Author(s) : Lukas RJ , Changeux JP , Le Novere N , Albuquerque EX , Balfour DJ , Berg DK , Bertrand D , Chiappinelli VA , Clarke PB , Collins AC , Dani JA , Grady SR , Kellar KJ , Lindstrom JM , Marks MJ , Quik M , Taylor P , Wonnacott S
Ref : Pharmacol Rev , 51 :397 , 1999
PubMedID: 10353988

Title : Two pharmacologically distinct components of nicotinic receptor-mediated rubidium efflux in mouse brain require the beta2 subunit - Marks_1999_J.Pharmacol.Exp.Ther_289_1090
Author(s) : Marks MJ , Whiteaker P , Calcaterra J , Stitzel JA , Bullock AE , Grady SR , Picciotto MR , Changeux JP , Collins AC
Ref : Journal of Pharmacology & Experimental Therapeutics , 289 :1090 , 1999
Abstract :
PubMedSearch : Marks_1999_J.Pharmacol.Exp.Ther_289_1090
PubMedID: 10215692