Activator-4-LYPLAL1
General
Type : Triazol, Benzofuran, Sulfonamide, Sulfure compound
Chemical_Nomenclature : 5-[(4-chlorophenyl)methylsulfanyl]-2-(2,3-dihydro-1-benzofuran-5-ylsulfonyl)-1,2,4-triazol-3-amine
Canonical SMILES : C1COC2=C1C=C(C=C2)S(=O)(=O)N3C(=NC(=N3)SCC4=CC=C(C=C4)Cl)N
InChI : InChI=1S\/C17H15ClN4O3S2\/c18-13-3-1-11(2-4-13)10-26-17-20-16(19)22(21-17)27(23,24)14-5-6-15-12(9-14)7-8-25-15\/h1-6,9H,7-8,10H2,(H2,19,20,21)
InChIKey : YDRIWANEBBWTMK-UHFFFAOYSA-N
Other name(s) :
MW : 422.9
Formula : C17H15ClN4O3S2
CAS_number :
PubChem : 146020332
UniChem : YDRIWANEBBWTMK-UHFFFAOYSA-N
Target
Families : LYsophospholipase_carboxylesterase
Protein : human-LYPLA1, mouse-lypla1
References (1)
| Title : Discovery of small-molecule enzyme activators by activity-based protein profiling - Kok_2020_Nat.Chem.Biol_16_997 |
| Author(s) : Kok BP , Ghimire S , Kim W , Chatterjee S , Johns T , Kitamura S , Eberhardt J , Ogasawara D , Xu J , Sukiasyan A , Kim SM , Godio C , Bittencourt JM , Cameron M , Galmozzi A , Forli S , Wolan DW , Cravatt BF , Boger DL , Saez E |
| Ref : Nat Chemical Biology , 16 :997 , 2020 |
| Abstract : Kok_2020_Nat.Chem.Biol_16_997 |
| ESTHER : Kok_2020_Nat.Chem.Biol_16_997 |
| PubMedSearch : Kok_2020_Nat.Chem.Biol_16_997 |
| PubMedID: 32514184 |
| Gene_locus related to this paper: human-LYPLAL1 |