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Author(s) : Kok BP , Ghimire S , Kim W , Chatterjee S , Johns T , Kitamura S , Eberhardt J , Ogasawara D , Xu J , Sukiasyan A , Kim SM , Godio C , Bittencourt JM , Cameron M , Galmozzi A , Forli S , Wolan DW , Cravatt BF , Boger DL , Saez E |
Ref : Nat Chemical Biology , 16 :997 , 2020 |
Abstract : |
PubMedSearch : Kok_2020_Nat.Chem.Biol_16_997 |
PubMedID: 32514184 |
Gene_locus related to this paper: human-LYPLAL1 |
Title : N-Acyl pyrazoles: Effective and tunable inhibitors of serine hydrolases - Otrubova_2019_Bioorg.Med.Chem_27_1693 |
Author(s) : Otrubova K , Chatterjee S , Ghimire S , Cravatt BF , Boger DL |
Ref : Bioorganic & Medicinal Chemistry , 27 :1693 , 2019 |
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PubMedSearch : Otrubova_2019_Bioorg.Med.Chem_27_1693 |
PubMedID: 30879861 |
Title : Design of Benzoxathiazin-3-one 1,1-Dioxides as a New Class of Irreversible Serine Hydrolase Inhibitors: Discovery of a Uniquely Selective PNPLA4 Inhibitor - Kornahrens_2017_J.Am.Chem.Soc_139_7052 |
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PubMedSearch : Kornahrens_2017_J.Am.Chem.Soc_139_7052 |
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PubMedSearch : Janssen_2015_J.Med.Chem_58_9742 |
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PubMedSearch : Zhao_2015_ACS.Chem.Biol_10_364 |
PubMedID: 25457457 |
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PubMedSearch : Otrubova_2014_Bioorg.Med.Chem.Lett_24_3807 |
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Ref : Journal of Pharmacology & Experimental Therapeutics , 330 :902 , 2009 |
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PubMedSearch : DeMartino_2008_Bioorg.Med.Chem.Lett_18_5842 |
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Author(s) : Lichtman AH , Leung D , Shelton CC , Saghatelian A , Hardouin C , Boger DL , Cravatt BF |
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PubMedSearch : Lichtman_2004_J.Pharmacol.Exp.Ther_311_441 |
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PubMedSearch : Boger_2001_J.Org.Chem_66_5163 |
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Author(s) : Boger DL , Sato H , Lerner AE , Hedrick MP , Fecik RA , Miyauchi H , Wilkie GD , Austin BJ , Patricelli MP , Cravatt BF |
Ref : Proc Natl Acad Sci U S A , 97 :5044 , 2000 |
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PubMedSearch : Boger_2000_Proc.Natl.Acad.Sci.U.S.A_97_5044 |
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