Antigen85c
Relationship
Comment
This family contains EC 3.1.2.12, human Esterase D and bacterial S-formylglutathione hydrolase. A universal pathway for formaldehyde detoxification. It also contains Antigen85c responsible for high affinity of mycobacteria to fibronectin. This family contains enterobactin, enterochelin enterobactin and salmochelin siderophore esterases also (IroD FES IroE). It also contains enzymes with acetyl xylan esterase (EC 3.1.1.72); cinnamoyl esterase (EC 3.1.1.-); feruloyl esterase (EC 3.1.1.73) activities corresponding to a subset of the Carbohydrate Esterase family CE1 in CAZy - Carbohydrate-Active enZYmes database (CE_1)
Database
Interpro : IPR000801 Esterase_put
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : PF00756 Esterase
Prints : No Print
EC Number : 3.1.2.12 || 3.1.1.72 || 3.1.1.73 || 2.3.1.20
Sequences
| Peptide in | Fasta |
| Nucleotide in | Fasta |
| Alignment with Multalin | Text only |
| Seed alignment with MAFFT | No colour / coloured with Mview |
| Alignment with MAFFT | No colour / coloured with Mview |
| Dendrogram | The dnd file |
| Substrate | Chemical Nomenclature | Proteins |
|---|---|---|
| S-Formylglutathione | (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-3-formylsulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid | human-ESD |
References (6)
| Title : A Global Survey of Carbohydrate Esterase Families 1 and 10 in Oomycetes - de Vries_2020_Front.Genet_11_756 |
| Author(s) : de Vries S , de Vries J |
| Ref : Front Genet , 11 :756 , 2020 |
| Abstract : |
| PubMedSearch : de Vries_2020_Front.Genet_11_756 |
| PubMedID: 32849784 |
| Title : Structural characterization and reversal of the natural organophosphate resistance of a D-type esterase, Saccharomyces cerevisiae S-formylglutathione hydrolase - Legler_2008_Biochemistry_47_9592 |
| Author(s) : Legler PM , Kumaran D , Swaminathan S , Studier FW , Millard CB |
| Ref : Biochemistry , 47 :9592 , 2008 |
| Abstract : |
| PubMedSearch : Legler_2008_Biochemistry_47_9592 |
| PubMedID: 18707125 |
| Gene_locus related to this paper: yeast-yjg8 |
| Title : Structural characterization of enterobactin hydrolase IroE - Larsen_2006_Biochemistry_45_10184 |
| Author(s) : Larsen NA , Lin H , Wei R , Fischbach MA , Walsh CT |
| Ref : Biochemistry , 45 :10184 , 2006 |
| Abstract : |
| PubMedSearch : Larsen_2006_Biochemistry_45_10184 |
| PubMedID: 16922493 |
| Gene_locus related to this paper: ecoli-IROE |
| Title : Molecular determinants of substrate specificity in the feruloyl esterase module of xylanase 10B from Clostridium thermocellum - Tarbouriech_2005_Acta.Crystallogr.D.Biol.Crystallogr_61_194 |
| Author(s) : Tarbouriech N , Prates JA , Fontes CM , Davies GJ |
| Ref : Acta Crystallographica D Biol Crystallogr , 61 :194 , 2005 |
| Abstract : |
| PubMedSearch : Tarbouriech_2005_Acta.Crystallogr.D.Biol.Crystallogr_61_194 |
| PubMedID: 15681871 |
| Gene_locus related to this paper: clotm-xyny |
| Title : Mycobacterium tuberculosis antigen 85A and 85C structures confirm binding orientation and conserved substrate specificity - Ronning_2004_J.Biol.Chem_279_36771 |
| Author(s) : Ronning DR , Vissa V , Besra GS , Belisle JT , Sacchettini JC |
| Ref : Journal of Biological Chemistry , 279 :36771 , 2004 |
| Abstract : |
| PubMedSearch : Ronning_2004_J.Biol.Chem_279_36771 |
| PubMedID: 15192106 |
| Gene_locus related to this paper: myctu-a85a , myctu-a85c |
| Title : The structure of Mycobacterium tuberculosis MPT51 (FbpC1) defines a new family of non-catalytic alpha\/beta hydrolases - Wilson_2004_J.Mol.Biol_335_519 |
| Author(s) : Wilson RA , Maughan WN , Kremer L , Besra GS , Futterer K |
| Ref : Journal of Molecular Biology , 335 :519 , 2004 |
| Abstract : |
| PubMedSearch : Wilson_2004_J.Mol.Biol_335_519 |
| PubMedID: 14672660 |
| Gene_locus related to this paper: myctu-mpt51 |