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Family Report for: Kynurenine-formamidase

Kynurenine-formamidase



Relationship
Block H
Comment
Kynurenine formamidase (EC:3.5.1.9) catalyses the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. It is required for elimination of toxic metabolites

Database
Sequences
Interpro
|
IPR027519 (Kynurenine formamidase, vertebrates/fungi-type KFase_ver/fungi-typ)
PIRSF
|
Pdoc
|
PFam
|
PF07859 (Abhydrolase_3)
Prints
|
Prosite
|
EC at KEGG
|
EC at EXPASY
|


Peptide in
|Fasta
Nucleotide in
|Fasta
Alignment with Multalin
|Text only/graphic display
Seed alignment with MAFFT
|No colour/coloured with Mview
Alignment with MAFFT
|No colour/coloured with Mview
Dendrogram
|Graphical display, obtained with the dnd file produced by Clustalw

References
1 more
    Title: Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster.
    Han Q, Robinson H, Li J
    Ref: Biochemical Journal, 446:253, 2012 : PubMed

            

    Title: Identification of formyl kynurenine formamidase and kynurenine aminotransferase from Saccharomyces cerevisiae using crystallographic, bioinformatic and biochemical evidence
    Wogulis M, Chew ER, Donohoue PD, Wilson DK
    Ref: Biochemistry, 47:1608, 2008 : PubMed

            

    Title: Crystal structure of an alpha/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 A resolution
    Arndt JW, Schwarzenbacher R, Page R, Abdubek P, Ambing E, Biorac T, Canaves JM, Chiu HJ, Dai X and Wilson IA <43 more author(s)>
    Ref: Proteins, 58:755, 2005 : PubMed

            

Other Papers


Structure scheme for Kynurenine-formamidase

Structures in Kynurenine-formamidase family (4)

Genes Proteins in Kynurenine-formamidase family (364)

Fragments of genes in Kynurenine-formamidase family (5)

Substrates of some enzymes in the Kynurenine-formamidase family (1)

Inhibitors of some enzymes in the Kynurenine-formamidase family (2)



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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