Kynurenine-formamidase
Relationship
Comment
Kynurenine formamidase (EC:3.5.1.9) catalyses the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. It is required for elimination of toxic metabolites
Database
Interpro : IPR027519 Kynurenine formamidase, vertebrates\/fungi-type KFase_ver\/fungi-typ
PIRSF : No PIRSF
Pdoc : No Pdoc
Pfam : PF07859 Abhydrolase_3
Prints : No Print
EC Number : 3.5.1.9
Structures (4)
Genes Proteins in Kynurenine-formamidase family (364)
Fragments of genes in Kynurenine-formamidase family (5)
Structures in Kynurenine-formamidase family (4)Substrates in Kynurenine-formamidase family (1)
Inhibitors in Kynurenine-formamidase family (2)
References (4)
| Title : Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster. - Han_2012_Biochem.J_446_253 |
| Author(s) : Han Q , Robinson H , Li J |
| Ref : Biochemical Journal , 446 :253 , 2012 |
| Abstract : Han_2012_Biochem.J_446_253 |
| ESTHER : Han_2012_Biochem.J_446_253 |
| PubMedSearch : Han_2012_Biochem.J_446_253 |
| PubMedID: 22690733 |
| Gene_locus related to this paper: drome-CG9542 |
| Title : Identification of formyl kynurenine formamidase and kynurenine aminotransferase from Saccharomyces cerevisiae using crystallographic, bioinformatic and biochemical evidence - Wogulis_2008_Biochemistry_47_1608 |
| Author(s) : Wogulis M , Chew ER , Donohoue PD , Wilson DK |
| Ref : Biochemistry , 47 :1608 , 2008 |
| Abstract : Wogulis_2008_Biochemistry_47_1608 |
| ESTHER : Wogulis_2008_Biochemistry_47_1608 |
| PubMedSearch : Wogulis_2008_Biochemistry_47_1608 |
| PubMedID: 18205391 |
| Gene_locus related to this paper: yeast-YDR428C |
| Title : Crystal structure of an alpha\/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 A resolution - |
| Author(s) : Arndt JW , Schwarzenbacher R , Page R , Abdubek P , Ambing E , Biorac T , Canaves JM , Chiu HJ , Dai X , Deacon AM , DiDonato M , Elsliger MA , Godzik A , Grittini C , Grzechnik SK , Hale J , Hampton E , Han GW , Haugen J , Hornsby M , Klock HE , Koesema E , Kreusch A , Kuhn P , Jaroszewski L , Lesley SA , Levin I , McMullan D , McPhillips TM , Miller MD , Morse A , Moy K , Nigoghossian E , Ouyang J , Peti WS , Quijano K , Reyes R , Sims E , Spraggon G , Stevens RC , van den Bedem H , Velasquez J , Vincent J , von Delft F , Wang X , West B , White A , Wolf G , Xu Q , Zagnitko O , Hodgson KO , Wooley J , Wilson IA |
| Ref : Proteins , 58 :755 , 2005 |
| PubMedID: 15624212 |
| Gene_locus related to this paper: yeast-YDR428C |
| Title : Biochemical and genetic characterization of kynurenine formamidase from Drosophila melanogaster - Moore_1978_Biochem.Genet_16_619 |
| Author(s) : Moore GP , Sullivan DT |
| Ref : Biochemical Genetics , 16 :619 , 1978 |
| Abstract : Moore_1978_Biochem.Genet_16_619 |
| ESTHER : Moore_1978_Biochem.Genet_16_619 |
| PubMedSearch : Moore_1978_Biochem.Genet_16_619 |
| PubMedID: 83140 |
| Gene_locus related to this paper: drome-CG9542 |