drome-CG9542
Drosophila melanogaster (Fruit fly) kynurenine formamidase cg9542 protein (rh42281p)
Comment
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites.
Relationship
Family : Kynurenine-formamidase
Block : H
Position in NCBI Life Tree : Drosophila melanogaster
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Protostomia N E > Ecdysozoa N E > Panarthropoda N E > Arthropoda N E > Mandibulata N E > Pancrustacea N E > Hexapoda N E > Insecta N E > Dicondylia N E > Pterygota N E > Neoptera N E > Holometabola N E > Diptera N E > Brachycera N E > Muscomorpha N E > Eremoneura N E > Cyclorrhapha N E > Schizophora N E > Acalyptratae N E > Ephydroidea N E > Drosophilidae N E > Drosophilinae N E > Drosophilini N E > Drosophila [fruit fly, genus] N E > Sophophora N E > melanogaster group N E > melanogaster subgroup N E > Drosophila melanogaster N E > cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Protostomia N E > Ecdysozoa N E > Panarthropoda N E > Arthropoda N E > Mandibulata N E > Pancrustacea N E > Hexapoda N E > Insecta N E > Dicondylia N E > Pterygota N E > Neoptera N E > Holometabola N E > Diptera N E > Brachycera N E > Muscomorpha N E > Eremoneura N E > Cyclorrhapha N E > Schizophora N E > Acalyptratae N E > Ephydroidea N E > Drosophilidae N E > Drosophilinae N E > Drosophilini N E > Drosophila [fruit fly, genus] N E > Sophophora N E > melanogaster group N E > melanogaster subgroup N E > Drosophila melanogaster N E > cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Protostomia N E > Ecdysozoa N E > Panarthropoda N E > Arthropoda N E > Mandibulata N E > Pancrustacea N E > Hexapoda N E > Insecta N E > Dicondylia N E > Pterygota N E > Neoptera N E > Holometabola N E > Diptera N E > Brachycera N E > Muscomorpha N E > Eremoneura N E > Cyclorrhapha N E > Schizophora N E > Acalyptratae N E > Ephydroidea N E > Drosophilidae N E > Drosophilinae N E > Drosophilini N E > Drosophila [fruit fly, genus] N E > Sophophora N E > melanogaster group N E > melanogaster subgroup N E > Drosophila melanogaster N EMolecular evidence
No mutation
4E11 - Crystal structure of kynurenine formamidase from Drosophila melanogaster
4E11 - Crystal structure of kynurenine formamidase from Drosophila melanogaster
4E11 - Crystal structure of kynurenine formamidase from Drosophila melanogaster
4E14 - Crystal structure of kynurenine formamidase from Drosophila melanogaster conjugated with phenylmethylsulfonyl fluoride
4E14 - Crystal structure of kynurenine formamidase from Drosophila melanogaster conjugated with phenylmethylsulfonyl fluoride
4E14 - Crystal structure of kynurenine formamidase from Drosophila melanogaster conjugated with phenylmethylsulfonyl fluoride
4E15 - Crystal structure of kynurenine formamidase from Drosophila melanogaster conjugated with an inhibitor
4E15 - Crystal structure of kynurenine formamidase from Drosophila melanogaster conjugated with an inhibitor
4E15 - Crystal structure of kynurenine formamidase from Drosophila melanogaster conjugated with an inhibitor
No kinetic
No disease
Sequence
Peptide
MYNPRCKDLD RDYFPSYHTT RFQDQPEPNL AVLEHFVRVT KQHGRELTEK QGITVDHLRY GEGRQLVDVF YSEKTTNQAP LFVFVHGGYW QEMDMSMSCS IVGPLVRRGY RVAVMDYNLC PQVTLEQLMT QFTHFLNWIF DYTEMTKVSS LTFAGHSAGA HLLAQILMRP NVITAQRSKM VWALIFLCGV YDLRELSNLE SVNPKNILGL NERNIESVSP MLWEYTDVTV WNSTKIYVVA AEHDSTTFIE QSRHYADVLR KKGYKASFTL FKGYDHFDII EETAIDDSDV SRFLRNIEIE
References (33)
| Title : Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster. - Han_2012_Biochem.J_446_253 |
| Author(s) : Han Q , Robinson H , Li J |
| Ref : Biochemical Journal , 446 :253 , 2012 |
| Abstract : |
| PubMedSearch : Han_2012_Biochem.J_446_253 |
| PubMedID: 22690733 |
| Gene_locus related to this paper: drome-CG9542 |
| Title : Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster. - Han_2012_Biochem.J_446_253 |
| Author(s) : Han Q , Robinson H , Li J |
| Ref : Biochemical Journal , 446 :253 , 2012 |
| Abstract : |
| PubMedSearch : Han_2012_Biochem.J_446_253 |
| PubMedID: 22690733 |
| Gene_locus related to this paper: drome-CG9542 |
| Title : Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster. - Han_2012_Biochem.J_446_253 |
| Author(s) : Han Q , Robinson H , Li J |
| Ref : Biochemical Journal , 446 :253 , 2012 |
| Abstract : |
| PubMedSearch : Han_2012_Biochem.J_446_253 |
| PubMedID: 22690733 |
| Gene_locus related to this paper: drome-CG9542 |
| Title : The Release 5.1 annotation of Drosophila melanogaster heterochromatin - Smith_2007_Science_316_1586 |
| Author(s) : Smith CD , Shu S , Mungall CJ , Karpen GH |
| Ref : Science , 316 :1586 , 2007 |
| Abstract : |
| PubMedSearch : Smith_2007_Science_316_1586 |
| PubMedID: 17569856 |
| Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-KRAKEN , drome-nrtac , drome-q8mqj5 |
| Title : Sequence finishing and mapping of Drosophila melanogaster heterochromatin - Hoskins_2007_Science_316_1625 |
| Author(s) : Hoskins RA , Carlson JW , Kennedy C , Acevedo D , Evans-Holm M , Frise E , Wan KH , Park S , Mendez-Lago M , Rossi F , Villasante A , Dimitri P , Karpen GH , Celniker SE |
| Ref : Science , 316 :1625 , 2007 |
| Abstract : |
| PubMedSearch : Hoskins_2007_Science_316_1625 |
| PubMedID: 17569867 |
| Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-KRAKEN , drome-nrtac , drome-q8mqj5 |
| Title : The Release 5.1 annotation of Drosophila melanogaster heterochromatin - Smith_2007_Science_316_1586 |
| Author(s) : Smith CD , Shu S , Mungall CJ , Karpen GH |
| Ref : Science , 316 :1586 , 2007 |
| Abstract : |
| PubMedSearch : Smith_2007_Science_316_1586 |
| PubMedID: 17569856 |
| Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-KRAKEN , drome-nrtac , drome-q8mqj5 |
| Title : Sequence finishing and mapping of Drosophila melanogaster heterochromatin - Hoskins_2007_Science_316_1625 |
| Author(s) : Hoskins RA , Carlson JW , Kennedy C , Acevedo D , Evans-Holm M , Frise E , Wan KH , Park S , Mendez-Lago M , Rossi F , Villasante A , Dimitri P , Karpen GH , Celniker SE |
| Ref : Science , 316 :1625 , 2007 |
| Abstract : |
| PubMedSearch : Hoskins_2007_Science_316_1625 |
| PubMedID: 17569867 |
| Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-KRAKEN , drome-nrtac , drome-q8mqj5 |
| Title : The Release 5.1 annotation of Drosophila melanogaster heterochromatin - Smith_2007_Science_316_1586 |
| Author(s) : Smith CD , Shu S , Mungall CJ , Karpen GH |
| Ref : Science , 316 :1586 , 2007 |
| Abstract : |
| PubMedSearch : Smith_2007_Science_316_1586 |
| PubMedID: 17569856 |
| Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-KRAKEN , drome-nrtac , drome-q8mqj5 |
| Title : Sequence finishing and mapping of Drosophila melanogaster heterochromatin - Hoskins_2007_Science_316_1625 |
| Author(s) : Hoskins RA , Carlson JW , Kennedy C , Acevedo D , Evans-Holm M , Frise E , Wan KH , Park S , Mendez-Lago M , Rossi F , Villasante A , Dimitri P , Karpen GH , Celniker SE |
| Ref : Science , 316 :1625 , 2007 |
| Abstract : |
| PubMedSearch : Hoskins_2007_Science_316_1625 |
| PubMedID: 17569867 |
| Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-KRAKEN , drome-nrtac , drome-q8mqj5 |
| Title : Combined evidence annotation of transposable elements in genome sequences - Quesneville_2005_PLoS.Comput.Biol_1_166 |
| Author(s) : Quesneville H , Bergman CM , Andrieu O , Autard D , Nouaud D , Ashburner M , Anxolabehere D |
| Ref : PLoS Comput Biol , 1 :166 , 2005 |
| Abstract : |
| PubMedSearch : Quesneville_2005_PLoS.Comput.Biol_1_166 |
| PubMedID: 16110336 |
| Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-KRAKEN , drome-nrtac , drome-q8mqj5 |
| Title : Combined evidence annotation of transposable elements in genome sequences - Quesneville_2005_PLoS.Comput.Biol_1_166 |
| Author(s) : Quesneville H , Bergman CM , Andrieu O , Autard D , Nouaud D , Ashburner M , Anxolabehere D |
| Ref : PLoS Comput Biol , 1 :166 , 2005 |
| Abstract : |
| PubMedSearch : Quesneville_2005_PLoS.Comput.Biol_1_166 |
| PubMedID: 16110336 |
| Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-KRAKEN , drome-nrtac , drome-q8mqj5 |
| Title : Combined evidence annotation of transposable elements in genome sequences - Quesneville_2005_PLoS.Comput.Biol_1_166 |
| Author(s) : Quesneville H , Bergman CM , Andrieu O , Autard D , Nouaud D , Ashburner M , Anxolabehere D |
| Ref : PLoS Comput Biol , 1 :166 , 2005 |
| Abstract : |
| PubMedSearch : Quesneville_2005_PLoS.Comput.Biol_1_166 |
| PubMedID: 16110336 |
| Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-KRAKEN , drome-nrtac , drome-q8mqj5 |
| Title : Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence - Celniker_2002_Genome.Biol_3_RESEARCH0079 |
| Author(s) : Celniker SE , Wheeler DA , Kronmiller B , Carlson JW , Halpern A , Patel S , Adams M , Champe M , Dugan SP , Frise E , Hodgson A , George RA , Hoskins RA , Laverty T , Muzny DM , Nelson CR , Pacleb JM , Park S , Pfeiffer BD , Richards S , Sodergren EJ , Svirskas R , Tabor PE , Wan K , Stapleton M , Sutton GG , Venter C , Weinstock G , Scherer SE , Myers EW , Gibbs RA , Rubin GM |
| Ref : Genome Biol , 3 :RESEARCH0079 , 2002 |
| Abstract : |
| PubMedSearch : Celniker_2002_Genome.Biol_3_RESEARCH0079 |
| PubMedID: 12537568 |
| Gene_locus related to this paper: drome-CG8058 , drome-CG9542 , drome-CG11309 , drome-CG11406 , drome-CG17097 , drome-CG17374 , drome-glita , drome-KRAKEN , drome-q8mqj5 |
| Title : The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective - Kaminker_2002_Genome.Biol_3_RESEARCH0084 |
| Author(s) : Kaminker JS , Bergman CM , Kronmiller B , Carlson J , Svirskas R , Patel S , Frise E , Wheeler DA , Lewis SE , Rubin GM , Ashburner M , Celniker SE |
| Ref : Genome Biol , 3 :RESEARCH0084 , 2002 |
| Abstract : |
| PubMedSearch : Kaminker_2002_Genome.Biol_3_RESEARCH0084 |
| PubMedID: 12537573 |
| Gene_locus related to this paper: drome-CG8058 , drome-CG9542 , drome-CG11309 , drome-CG11406 , drome-CG17097 , drome-glita , drome-KRAKEN , drome-q8mqj5 |
| Title : Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence - Celniker_2002_Genome.Biol_3_RESEARCH0079 |
| Author(s) : Celniker SE , Wheeler DA , Kronmiller B , Carlson JW , Halpern A , Patel S , Adams M , Champe M , Dugan SP , Frise E , Hodgson A , George RA , Hoskins RA , Laverty T , Muzny DM , Nelson CR , Pacleb JM , Park S , Pfeiffer BD , Richards S , Sodergren EJ , Svirskas R , Tabor PE , Wan K , Stapleton M , Sutton GG , Venter C , Weinstock G , Scherer SE , Myers EW , Gibbs RA , Rubin GM |
| Ref : Genome Biol , 3 :RESEARCH0079 , 2002 |
| Abstract : |
| PubMedSearch : Celniker_2002_Genome.Biol_3_RESEARCH0079 |
| PubMedID: 12537568 |
| Gene_locus related to this paper: drome-CG8058 , drome-CG9542 , drome-CG11309 , drome-CG11406 , drome-CG17097 , drome-CG17374 , drome-glita , drome-KRAKEN , drome-q8mqj5 |
| Title : The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective - Kaminker_2002_Genome.Biol_3_RESEARCH0084 |
| Author(s) : Kaminker JS , Bergman CM , Kronmiller B , Carlson J , Svirskas R , Patel S , Frise E , Wheeler DA , Lewis SE , Rubin GM , Ashburner M , Celniker SE |
| Ref : Genome Biol , 3 :RESEARCH0084 , 2002 |
| Abstract : |
| PubMedSearch : Kaminker_2002_Genome.Biol_3_RESEARCH0084 |
| PubMedID: 12537573 |
| Gene_locus related to this paper: drome-CG8058 , drome-CG9542 , drome-CG11309 , drome-CG11406 , drome-CG17097 , drome-glita , drome-KRAKEN , drome-q8mqj5 |
| Title : Heterochromatic sequences in a Drosophila whole-genome shotgun assembly - Hoskins_2002_Genome.Biol_3_RESEARCH0085 |
| Author(s) : Hoskins RA , Smith CD , Carlson JW , Carvalho AB , Halpern A , Kaminker JS , Kennedy C , Mungall CJ , Sullivan BA , Sutton GG , Yasuhara JC , Wakimoto BT , Myers EW , Celniker SE , Rubin GM , Karpen GH |
| Ref : Genome Biol , 3 :RESEARCH0085 , 2002 |
| Abstract : |
| PubMedSearch : Hoskins_2002_Genome.Biol_3_RESEARCH0085 |
| PubMedID: 12537574 |
| Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-CG17097 , drome-CG17374 , drome-KRAKEN , drome-q8mqj5 |
| Title : Finishing a whole-genome shotgun: release 3 of the Drosophila melanogaster euchromatic genome sequence - Celniker_2002_Genome.Biol_3_RESEARCH0079 |
| Author(s) : Celniker SE , Wheeler DA , Kronmiller B , Carlson JW , Halpern A , Patel S , Adams M , Champe M , Dugan SP , Frise E , Hodgson A , George RA , Hoskins RA , Laverty T , Muzny DM , Nelson CR , Pacleb JM , Park S , Pfeiffer BD , Richards S , Sodergren EJ , Svirskas R , Tabor PE , Wan K , Stapleton M , Sutton GG , Venter C , Weinstock G , Scherer SE , Myers EW , Gibbs RA , Rubin GM |
| Ref : Genome Biol , 3 :RESEARCH0079 , 2002 |
| Abstract : |
| PubMedSearch : Celniker_2002_Genome.Biol_3_RESEARCH0079 |
| PubMedID: 12537568 |
| Gene_locus related to this paper: drome-CG8058 , drome-CG9542 , drome-CG11309 , drome-CG11406 , drome-CG17097 , drome-CG17374 , drome-glita , drome-KRAKEN , drome-q8mqj5 |
| Title : Heterochromatic sequences in a Drosophila whole-genome shotgun assembly - Hoskins_2002_Genome.Biol_3_RESEARCH0085 |
| Author(s) : Hoskins RA , Smith CD , Carlson JW , Carvalho AB , Halpern A , Kaminker JS , Kennedy C , Mungall CJ , Sullivan BA , Sutton GG , Yasuhara JC , Wakimoto BT , Myers EW , Celniker SE , Rubin GM , Karpen GH |
| Ref : Genome Biol , 3 :RESEARCH0085 , 2002 |
| Abstract : |
| PubMedSearch : Hoskins_2002_Genome.Biol_3_RESEARCH0085 |
| PubMedID: 12537574 |
| Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-CG17097 , drome-CG17374 , drome-KRAKEN , drome-q8mqj5 |
| Title : The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective - Kaminker_2002_Genome.Biol_3_RESEARCH0084 |
| Author(s) : Kaminker JS , Bergman CM , Kronmiller B , Carlson J , Svirskas R , Patel S , Frise E , Wheeler DA , Lewis SE , Rubin GM , Ashburner M , Celniker SE |
| Ref : Genome Biol , 3 :RESEARCH0084 , 2002 |
| Abstract : |
| PubMedSearch : Kaminker_2002_Genome.Biol_3_RESEARCH0084 |
| PubMedID: 12537573 |
| Gene_locus related to this paper: drome-CG8058 , drome-CG9542 , drome-CG11309 , drome-CG11406 , drome-CG17097 , drome-glita , drome-KRAKEN , drome-q8mqj5 |
| Title : Heterochromatic sequences in a Drosophila whole-genome shotgun assembly - Hoskins_2002_Genome.Biol_3_RESEARCH0085 |
| Author(s) : Hoskins RA , Smith CD , Carlson JW , Carvalho AB , Halpern A , Kaminker JS , Kennedy C , Mungall CJ , Sullivan BA , Sutton GG , Yasuhara JC , Wakimoto BT , Myers EW , Celniker SE , Rubin GM , Karpen GH |
| Ref : Genome Biol , 3 :RESEARCH0085 , 2002 |
| Abstract : |
| PubMedSearch : Hoskins_2002_Genome.Biol_3_RESEARCH0085 |
| PubMedID: 12537574 |
| Gene_locus related to this paper: drome-CG9542 , drome-CG11309 , drome-CG17097 , drome-CG17374 , drome-KRAKEN , drome-q8mqj5 |
| Title : Biochemical and genetic characterization of kynurenine formamidase from Drosophila melanogaster - Moore_1978_Biochem.Genet_16_619 |
| Author(s) : Moore GP , Sullivan DT |
| Ref : Biochemical Genetics , 16 :619 , 1978 |
| Abstract : |
| PubMedSearch : Moore_1978_Biochem.Genet_16_619 |
| PubMedID: 83140 |
| Gene_locus related to this paper: drome-CG9542 |
| Title : Biochemical and genetic characterization of kynurenine formamidase from Drosophila melanogaster - Moore_1978_Biochem.Genet_16_619 |
| Author(s) : Moore GP , Sullivan DT |
| Ref : Biochemical Genetics , 16 :619 , 1978 |
| Abstract : |
| PubMedSearch : Moore_1978_Biochem.Genet_16_619 |
| PubMedID: 83140 |
| Gene_locus related to this paper: drome-CG9542 |
| Title : Biochemical and genetic characterization of kynurenine formamidase from Drosophila melanogaster - Moore_1978_Biochem.Genet_16_619 |
| Author(s) : Moore GP , Sullivan DT |
| Ref : Biochemical Genetics , 16 :619 , 1978 |
| Abstract : |
| PubMedSearch : Moore_1978_Biochem.Genet_16_619 |
| PubMedID: 83140 |
| Gene_locus related to this paper: drome-CG9542 |