1. Home
  2. Gene Locus
  3. yeast-YDR428C

yeast-YDR428C

Saccharomyces cerevisiae (Baker's yeast); Saccharomyces sp. Kynurenine formamidase KFA d9461.15p

Comment

Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. Other strains: Saccharomyces cerevisiae (strains FostersB\; Zymaflore VL3\; JAY291\; AWRI796\; Lalvin QA23\; YJM789\; AWRI1631\; ATCC 204508 \/ S288c\; RM11-1a\; YJM993\; P301\; R103\; Kyokai no. 7 \/ NBRC 101557\; CEN.PK113-7D\; R008\; P283)\; Saccharomyces sp.

Relationship

Family : Kynurenine-formamidase

Block : H

Position in NCBI Life Tree : Saccharomyces cerevisiae

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Fungi N E > Dikarya N E > Ascomycota N E > saccharomyceta N E > Saccharomycotina N E > Saccharomycetes N E > Saccharomycetales N E > Saccharomycetaceae N E > Saccharomyces N E > Saccharomyces cerevisiae N E

Molecular evidence

No mutation

No kinetic

No disease

No inhibitor

Database

Sequence

Peptide

MSNTVRAISP DITLFNKTLT FQEISQNTRE AVIYIHGGAW NDPENTPNDF NQLANTIKSM DTESTVCQYS IEYRLSPEIT NPRNLYDAVS NITRLVKEKG LTNINMVGHS VGATFIWQIL AALKDPQEKM SEAQLQMLGL LQIVKRVFLL DGIYSLKELL VEYPEYDCFT RLAFPDGIQM YEEEPSRVMP YVKKALSRFS IDMHLVHSYS DELLTLRQTN CLISCLQDYQ LSFKLYLDDL GLHNDVYKNG KVAKYIFDNI C

References (14)

Title : The impact of genomic variability on gene expression in environmental Saccharomyces cerevisiae strains - Treu_2014_Environ.Microbiol_16_1378
Author(s) : Treu L , Toniolo C , Nadai C , Sardu A , Giacomini A , Corich V , Campanaro S
Ref : Environ Microbiol , 16 :1378 , 2014
Abstract :
PubMedSearch : Treu_2014_Environ.Microbiol_16_1378
PubMedID: 24238297
Gene_locus related to this paper: yeast-YDR428C

Title : De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnology - Nijkamp_2012_Microb.Cell.Fact_11_36
Author(s) : Nijkamp JF , van den Broek M , Datema E , de Kok S , Bosman L , Luttik MA , Daran-Lapujade P , Vongsangnak W , Nielsen J , Heijne WH , Klaassen P , Paddon CJ , Platt D , Kotter P , van Ham RC , Reinders MJ , Pronk JT , de Ridder D , Daran JM
Ref : Microb Cell Fact , 11 :36 , 2012
Abstract :
PubMedSearch : Nijkamp_2012_Microb.Cell.Fact_11_36
PubMedID: 22448915
Gene_locus related to this paper: yeast-YDR428C , yeast-hda1

Title : Whole-genome sequencing of sake yeast Saccharomyces cerevisiae Kyokai no. 7 - Akao_2011_DNA.Res_18_423
Author(s) : Akao T , Yashiro I , Hosoyama A , Kitagaki H , Horikawa H , Watanabe D , Akada R , Ando Y , Harashima S , Inoue T , Inoue Y , Kajiwara S , Kitamoto K , Kitamoto N , Kobayashi O , Kuhara S , Masubuchi T , Mizoguchi H , Nakao Y , Nakazato A , Namise M , Oba T , Ogata T , Ohta A , Sato M , Shibasaki S , Takatsume Y , Tanimoto S , Tsuboi H , Nishimura A , Yoda K , Ishikawa T , Iwashita K , Fujita N , Shimoi H
Ref : DNA Research , 18 :423 , 2011
Abstract :
PubMedSearch : Akao_2011_DNA.Res_18_423
PubMedID: 21900213
Gene_locus related to this paper: yeast-YDR428C , yeast-hda1

Title : Eukaryote-to-eukaryote gene transfer events revealed by the genome sequence of the wine yeast Saccharomyces cerevisiae EC1118 - Novo_2009_Proc.Natl.Acad.Sci.U.S.A_106_16333
Author(s) : Novo M , Bigey F , Beyne E , Galeote V , Gavory F , Mallet S , Cambon B , Legras JL , Wincker P , Casaregola S , Dequin S
Ref : Proc Natl Acad Sci U S A , 106 :16333 , 2009
Abstract :
PubMedSearch : Novo_2009_Proc.Natl.Acad.Sci.U.S.A_106_16333
PubMedID: 19805302
Gene_locus related to this paper: yeast-AIM2 , yeast-BST1 , yeast-cbpy1 , yeast-cld1 , yeast-dap1 , yeast-dap2 , yeast-dlhh , yeast-ECM18 , yeast-FSH1 , yeast-FSH3 , yeast-ict1 , yeast-kex01 , yeast-MCFS1 , yeast-MCFS2 , yeast-met2 , yeast-mgll , yeast-pdat , yeast-ppme1 , yeast-ROG1 , yeast-SAY1 , yeast-tgl1 , yeast-tgl2 , yeast-yby9 , yeast-YDL109C , yeast-YDR428C , yeast-YDR444W , yeast-yg19 , yeast-yj77 , yeast-yjg8 , yeast-YLL012W , yeast-YLR020C , yeast-YLR118c , yeast-ym60 , yeast-ynl5 , yeast-yo059 , yeast-YPR147C , yeast-hda1

Title : Genome structure of a Saccharomyces cerevisiae strain widely used in bioethanol production - Argueso_2009_Genome.Res_19_2258
Author(s) : Argueso JL , Carazzolle MF , Mieczkowski PA , Duarte FM , Netto OV , Missawa SK , Galzerani F , Costa GG , Vidal RO , Noronha MF , Dominska M , Andrietta MG , Andrietta SR , Cunha AF , Gomes LH , Tavares FC , Alcarde AR , Dietrich FS , McCusker JH , Petes TD , Pereira GA
Ref : Genome Res , 19 :2258 , 2009
Abstract :
PubMedSearch : Argueso_2009_Genome.Res_19_2258
PubMedID: 19812109
Gene_locus related to this paper: yeast-AIM2 , yeast-BST1 , yeast-cbpy1 , yeast-cld1 , yeast-dap1 , yeast-dap2 , yeast-dlhh , yeast-ECM18 , yeast-FSH1 , yeast-FSH3 , yeast-ict1 , yeast-kex01 , yeast-LDH1 , yeast-MCFS1 , yeast-MCFS2 , yeast-met2 , yeast-mgll , yeast-pdat , yeast-ppme1 , yeast-ROG1 , yeast-SAY1 , yeast-tgl1 , yeast-tgl2 , yeast-yby9 , yeast-YDL109C , yeast-YDR428C , yeast-YDR444W , yeast-yg19 , yeast-yj77 , yeast-yjg8 , yeast-YLL012W , yeast-YLR020C , yeast-YLR118c , yeast-ym60 , yeast-ynl5 , yeast-yo059 , yeast-YPR147C , yeast-hda1

Title : Identification of formyl kynurenine formamidase and kynurenine aminotransferase from Saccharomyces cerevisiae using crystallographic, bioinformatic and biochemical evidence - Wogulis_2008_Biochemistry_47_1608
Author(s) : Wogulis M , Chew ER , Donohoue PD , Wilson DK
Ref : Biochemistry , 47 :1608 , 2008
Abstract :
PubMedSearch : Wogulis_2008_Biochemistry_47_1608
PubMedID: 18205391
Gene_locus related to this paper: yeast-YDR428C

Title : A multidimensional chromatography technology for in-depth phosphoproteome analysis - Albuquerque_2008_Mol.Cell.Proteomics_7_1389
Author(s) : Albuquerque CP , Smolka MB , Payne SH , Bafna V , Eng J , Zhou H
Ref : Mol Cell Proteomics , 7 :1389 , 2008
Abstract :
PubMedSearch : Albuquerque_2008_Mol.Cell.Proteomics_7_1389
PubMedID: 18407956
Gene_locus related to this paper: yeast-YDR428C , yeast-YDR444W , yeast-yfd4

Title : Comparative genome analysis of a Saccharomyces cerevisiae wine strain - Borneman_2008_FEMS.Yeast.Res_8_1185
Author(s) : Borneman AR , Forgan AH , Pretorius IS , Chambers PJ
Ref : FEMS Yeast Res , 8 :1185 , 2008
Abstract :
PubMedSearch : Borneman_2008_FEMS.Yeast.Res_8_1185
PubMedID: 18778279
Gene_locus related to this paper: yeast-AIM2 , yeast-BST1 , yeast-cbpy1 , yeast-cld1 , yeast-dap1 , yeast-dap2 , yeast-dlhh , yeast-ECM18 , yeast-FSH1 , yeast-FSH3 , yeast-ict1 , yeast-kex01 , yeast-LDH1 , yeast-MCFS1 , yeast-MCFS2 , yeast-met2 , yeast-mgll , yeast-pdat , yeast-ppme1 , yeast-ROG1 , yeast-SAY1 , yeast-tgl1 , yeast-tgl2 , yeast-yby9 , yeast-YDR428C , yeast-YDR444W , yeast-yfd4 , yeast-yg19 , yeast-yj68 , yeast-yj77 , yeast-yjg8 , yeast-YLL012W , yeast-YLR020C , yeast-YLR118c , yeast-ym60 , yeast-ynl5 , yeast-yo059 , yeast-YPR147C , yeast-hda1

Title : Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae - Li_2007_J.Proteome.Res_6_1190
Author(s) : Li X , Gerber SA , Rudner AD , Beausoleil SA , Haas W , Villen J , Elias JE , Gygi SP
Ref : J Proteome Res , 6 :1190 , 2007
Abstract :
PubMedSearch : Li_2007_J.Proteome.Res_6_1190
PubMedID: 17330950
Gene_locus related to this paper: yeast-YDR428C

Title : Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789 - Wei_2007_Proc.Natl.Acad.Sci.U.S.A_104_12825
Author(s) : Wei W , McCusker JH , Hyman RW , Jones T , Ning Y , Cao Z , Gu Z , Bruno D , Miranda M , Nguyen M , Wilhelmy J , Komp C , Tamse R , Wang X , Jia P , Luedi P , Oefner PJ , David L , Dietrich FS , Li Y , Davis RW , Steinmetz LM
Ref : Proc Natl Acad Sci U S A , 104 :12825 , 2007
Abstract :
PubMedSearch : Wei_2007_Proc.Natl.Acad.Sci.U.S.A_104_12825
PubMedID: 17652520
Gene_locus related to this paper: yeast-AIM2 , yeast-BST1 , yeast-cbpy1 , yeast-cld1 , yeast-ATG15 , yeast-dap1 , yeast-dap2 , yeast-dlhh , yeast-ECM18 , yeast-FSH1 , yeast-FSH3 , yeast-ict1 , yeast-kex01 , yeast-LDH1 , yeast-MCFS1 , yeast-MCFS2 , yeast-met2 , yeast-mgll , yeast-pdat , yeast-ppme1 , yeast-ROG1 , yeast-SAY1 , yeast-tgl1 , yeast-tgl2 , yeast-yby9 , yeast-YDL109C , yeast-YDR428C , yeast-YDR444W , yeast-yfd4 , yeast-yg19 , yeast-yj77 , yeast-yjg8 , yeast-YLL012W , yeast-YLR020C , yeast-YLR118c , yeast-ym60 , yeast-ynl5 , yeast-yo059 , yeast-YPR147C , yeast-hda1

Title : Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway - Gruhler_2005_Mol.Cell.Proteomics_4_310
Author(s) : Gruhler A , Olsen JV , Mohammed S , Mortensen P , Faergeman NJ , Mann M , Jensen ON
Ref : Mol Cell Proteomics , 4 :310 , 2005
Abstract :
PubMedSearch : Gruhler_2005_Mol.Cell.Proteomics_4_310
PubMedID: 15665377
Gene_locus related to this paper: yeast-YDR428C

Title : Crystal structure of an alpha\/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 A resolution -
Author(s) : Arndt JW , Schwarzenbacher R , Page R , Abdubek P , Ambing E , Biorac T , Canaves JM , Chiu HJ , Dai X , Deacon AM , DiDonato M , Elsliger MA , Godzik A , Grittini C , Grzechnik SK , Hale J , Hampton E , Han GW , Haugen J , Hornsby M , Klock HE , Koesema E , Kreusch A , Kuhn P , Jaroszewski L , Lesley SA , Levin I , McMullan D , McPhillips TM , Miller MD , Morse A , Moy K , Nigoghossian E , Ouyang J , Peti WS , Quijano K , Reyes R , Sims E , Spraggon G , Stevens RC , van den Bedem H , Velasquez J , Vincent J , von Delft F , Wang X , West B , White A , Wolf G , Xu Q , Zagnitko O , Hodgson KO , Wooley J , Wilson IA
Ref : Proteins , 58 :755 , 2005
PubMedID: 15624212
Gene_locus related to this paper: yeast-YDR428C

Title : Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast - Baxter_2004_Mol.Cell.Proteomics_3_209
Author(s) : Baxter SM , Rosenblum JS , Knutson S , Nelson MR , Montimurro JS , Di Gennaro JA , Speir JA , Burbaum JJ , Fetrow JS
Ref : Mol Cell Proteomics , 3 :209 , 2004
Abstract :
PubMedSearch : Baxter_2004_Mol.Cell.Proteomics_3_209
PubMedID: 14645503
Gene_locus related to this paper: yeast-FSH1 , yeast-FSH2 , yeast-FSH3 , yeast-mgll , yeast-ppme1 , yeast-YDR428C , yeast-yfd4 , yeast-YLR118c

Title : The nucleotide sequence of Saccharomyces cerevisiae chromosome IV - Jacq_1997_Nature_387_75
Author(s) : Jacq C , Alt-Morbe J , Andre B , Arnold W , Bahr A , Ballesta JP , Bargues M , Baron L , Becker A , Biteau N , Blocker H , Blugeon C , Boskovic J , Brandt P , Bruckner M , Buitrago MJ , Coster F , Delaveau T , del Rey F , Dujon B , Eide LG , Garcia-Cantalejo JM , Goffeau A , Gomez-Peris AC , Granotier C , Hanemann V , Hankeln T , Hoheisel JD , Jager W , Jimenez A , Jonniaux JL , Kramer C , Kuster H , Laamanen P , Legros Y , Louis E , Muller-Rieker S , Monnet A , Moro M , Muller-Auer S , Nussbaumer B , Paricio N , Paulin L , Perea J , Perez-Alonso M , Perez-Ortin JE , Pohl TM , Prydz H , Purnelle B , Rasmussen SW , Remacha M , Revuelta JL , Rieger M , Salom D , Saluz HP , Saiz JE , Saren AM , Schafer M , Scharfe M , Schmidt ER , Schneider C , Scholler P , Schwarz S , Soler-Mira A , Urrestarazu LA , Verhasselt P , Vissers S , Voet M , Volckaert G , Wagner G , Wambutt R , Wedler E , Wedler H , Wolfl S , Harris DE , Bowman S , Brown D , Churcher CM , Connor R , Dedman K , Gentles S , Hamlin N , Hunt S , Jones L , McDonald S , Murphy L , Niblett D , Odell C , Oliver K , Rajandream MA , Richards C , Shore L , Walsh SV , Barrell BG , Dietrich FS , Mulligan J , Allen E , Araujo R , Aviles E , Berno A , Carpenter J , Chen E , Cherry JM , Chung E , Duncan M , Hunicke-Smith S , Hyman R , Komp C , Lashkari D , Lew H , Lin D , Mosedale D , Nakahara K , Namath A , Oefner P , Oh C , Petel FX , Roberts D , Schramm S , Schroeder M , Shogren T , Shroff N , Winant A , Yelton M , Botstein D , Davis RW , Johnston M , Hillier L , Riles L , Albermann K , Hani J , Heumann K , Kleine K , Mewes HW , Zollner A , Zaccaria P
Ref : Nature , 387 :75 , 1997
Abstract :
PubMedSearch : Jacq_1997_Nature_387_75
PubMedID: 9169867
Gene_locus related to this paper: yeast-dlhh , yeast-ECM18 , yeast-YDL109C , yeast-YDR428C , yeast-YDR444W