yeast-YDR428C

Saccharomyces cerevisiae (Baker's yeast); Saccharomyces sp. Kynurenine formamidase KFA d9461.15p

Comment

Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. Other strains: Saccharomyces cerevisiae (strains FostersB\; Zymaflore VL3\; JAY291\; AWRI796\; Lalvin QA23\; YJM789\; AWRI1631\; ATCC 204508 \/ S288c\; RM11-1a\; YJM993\; P301\; R103\; Kyokai no. 7 \/ NBRC 101557\; CEN.PK113-7D\; R008\; P283)\; Saccharomyces sp.

Relationship

Family : Kynurenine-formamidase

Block : H

Position in NCBI Life Tree : Saccharomyces cerevisiae

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Fungi N E > Dikarya N E > Ascomycota N E > saccharomyceta N E > Saccharomycotina N E > Saccharomycetes N E > Saccharomycetales N E > Saccharomycetaceae N E > Saccharomyces N E > Saccharomyces cerevisiae N E

Molecular evidence

No mutation

No kinetic

No disease

No inhibitor

Sequence

Peptide

MSNTVRAISP DITLFNKTLT FQEISQNTRE AVIYIHGGAW NDPENTPNDF NQLANTIKSM DTESTVCQYS IEYRLSPEIT NPRNLYDAVS NITRLVKEKG LTNINMVGHS VGATFIWQIL AALKDPQEKM SEAQLQMLGL LQIVKRVFLL DGIYSLKELL VEYPEYDCFT RLAFPDGIQM YEEEPSRVMP YVKKALSRFS IDMHLVHSYS DELLTLRQTN CLISCLQDYQ LSFKLYLDDL GLHNDVYKNG KVAKYIFDNI C

References (14)

Title : The impact of genomic variability on gene expression in environmental Saccharomyces cerevisiae strains - Treu_2014_Environ.Microbiol_16_1378
Author(s) : Treu L , Toniolo C , Nadai C , Sardu A , Giacomini A , Corich V , Campanaro S
Ref : Environ Microbiol , 16 :1378 , 2014
PubMedID: 24238297
Gene_locus related to this paper: yeast-YDR428C

Title : De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnology - Nijkamp_2012_Microb.Cell.Fact_11_36
Author(s) : Nijkamp JF , van den Broek M , Datema E , de Kok S , Bosman L , Luttik MA , Daran-Lapujade P , Vongsangnak W , Nielsen J , Heijne WH , Klaassen P , Paddon CJ , Platt D , Kotter P , van Ham RC , Reinders MJ , Pronk JT , de Ridder D , Daran JM
Ref : Microb Cell Fact , 11 :36 , 2012
PubMedID: 22448915
Gene_locus related to this paper: yeast-YDR428C , yeast-hda1

Title : Whole-genome sequencing of sake yeast Saccharomyces cerevisiae Kyokai no. 7 - Akao_2011_DNA.Res_18_423
Author(s) : Akao T , Yashiro I , Hosoyama A , Kitagaki H , Horikawa H , Watanabe D , Akada R , Ando Y , Harashima S , Inoue T , Inoue Y , Kajiwara S , Kitamoto K , Kitamoto N , Kobayashi O , Kuhara S , Masubuchi T , Mizoguchi H , Nakao Y , Nakazato A , Namise M , Oba T , Ogata T , Ohta A , Sato M , Shibasaki S , Takatsume Y , Tanimoto S , Tsuboi H , Nishimura A , Yoda K , Ishikawa T , Iwashita K , Fujita N , Shimoi H
Ref : DNA Research , 18 :423 , 2011
PubMedID: 21900213
Gene_locus related to this paper: yeast-YDR428C , yeast-hda1

Title : Eukaryote-to-eukaryote gene transfer events revealed by the genome sequence of the wine yeast Saccharomyces cerevisiae EC1118 - Novo_2009_Proc.Natl.Acad.Sci.U.S.A_106_16333
Author(s) : Novo M , Bigey F , Beyne E , Galeote V , Gavory F , Mallet S , Cambon B , Legras JL , Wincker P , Casaregola S , Dequin S
Ref : Proc Natl Acad Sci U S A , 106 :16333 , 2009
PubMedID: 19805302
Gene_locus related to this paper: yeast-AIM2 , yeast-BST1 , yeast-cbpy1 , yeast-cld1 , yeast-dap1 , yeast-dap2 , yeast-dlhh , yeast-ECM18 , yeast-FSH1 , yeast-FSH3 , yeast-ict1 , yeast-kex01 , yeast-MCFS1 , yeast-MCFS2 , yeast-met2 , yeast-mgll , yeast-pdat , yeast-ppme1 , yeast-ROG1 , yeast-SAY1 , yeast-tgl1 , yeast-tgl2 , yeast-yby9 , yeast-YDL109C , yeast-YDR428C , yeast-YDR444W , yeast-yg19 , yeast-yj77 , yeast-yjg8 , yeast-YLL012W , yeast-YLR020C , yeast-YLR118c , yeast-ym60 , yeast-ynl5 , yeast-yo059 , yeast-YPR147C , yeast-hda1

Title : Identification of formyl kynurenine formamidase and kynurenine aminotransferase from Saccharomyces cerevisiae using crystallographic, bioinformatic and biochemical evidence - Wogulis_2008_Biochemistry_47_1608
Author(s) : Wogulis M , Chew ER , Donohoue PD , Wilson DK
Ref : Biochemistry , 47 :1608 , 2008
PubMedID: 18205391
Gene_locus related to this paper: yeast-YDR428C

Title : A multidimensional chromatography technology for in-depth phosphoproteome analysis - Albuquerque_2008_Mol.Cell.Proteomics_7_1389
Author(s) : Albuquerque CP , Smolka MB , Payne SH , Bafna V , Eng J , Zhou H
Ref : Mol Cell Proteomics , 7 :1389 , 2008
PubMedID: 18407956
Gene_locus related to this paper: yeast-YDR428C , yeast-YDR444W , yeast-yfd4

Title : Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae - Li_2007_J.Proteome.Res_6_1190
Author(s) : Li X , Gerber SA , Rudner AD , Beausoleil SA , Haas W , Villen J , Elias JE , Gygi SP
Ref : J Proteome Res , 6 :1190 , 2007
PubMedID: 17330950
Gene_locus related to this paper: yeast-YDR428C

Title : Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway - Gruhler_2005_Mol.Cell.Proteomics_4_310
Author(s) : Gruhler A , Olsen JV , Mohammed S , Mortensen P , Faergeman NJ , Mann M , Jensen ON
Ref : Mol Cell Proteomics , 4 :310 , 2005
PubMedID: 15665377
Gene_locus related to this paper: yeast-YDR428C

Title : Crystal structure of an alpha\/beta serine hydrolase (YDR428C) from Saccharomyces cerevisiae at 1.85 A resolution -
Author(s) : Arndt JW , Schwarzenbacher R , Page R , Abdubek P , Ambing E , Biorac T , Canaves JM , Chiu HJ , Dai X , Deacon AM , DiDonato M , Elsliger MA , Godzik A , Grittini C , Grzechnik SK , Hale J , Hampton E , Han GW , Haugen J , Hornsby M , Klock HE , Koesema E , Kreusch A , Kuhn P , Jaroszewski L , Lesley SA , Levin I , McMullan D , McPhillips TM , Miller MD , Morse A , Moy K , Nigoghossian E , Ouyang J , Peti WS , Quijano K , Reyes R , Sims E , Spraggon G , Stevens RC , van den Bedem H , Velasquez J , Vincent J , von Delft F , Wang X , West B , White A , Wolf G , Xu Q , Zagnitko O , Hodgson KO , Wooley J , Wilson IA
Ref : Proteins , 58 :755 , 2005
PubMedID: 15624212
Gene_locus related to this paper: yeast-YDR428C

Title : Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast - Baxter_2004_Mol.Cell.Proteomics_3_209
Author(s) : Baxter SM , Rosenblum JS , Knutson S , Nelson MR , Montimurro JS , Di Gennaro JA , Speir JA , Burbaum JJ , Fetrow JS
Ref : Mol Cell Proteomics , 3 :209 , 2004
PubMedID: 14645503
Gene_locus related to this paper: yeast-FSH1 , yeast-FSH2 , yeast-FSH3 , yeast-mgll , yeast-ppme1 , yeast-YDR428C , yeast-yfd4 , yeast-YLR118c

Title : The nucleotide sequence of Saccharomyces cerevisiae chromosome IV - Jacq_1997_Nature_387_75
Author(s) : Jacq C , Alt-Morbe J , Andre B , Arnold W , Bahr A , Ballesta JP , Bargues M , Baron L , Becker A , Biteau N , Blocker H , Blugeon C , Boskovic J , Brandt P , Bruckner M , Buitrago MJ , Coster F , Delaveau T , del Rey F , Dujon B , Eide LG , Garcia-Cantalejo JM , Goffeau A , Gomez-Peris AC , Granotier C , Hanemann V , Hankeln T , Hoheisel JD , Jager W , Jimenez A , Jonniaux JL , Kramer C , Kuster H , Laamanen P , Legros Y , Louis E , Muller-Rieker S , Monnet A , Moro M , Muller-Auer S , Nussbaumer B , Paricio N , Paulin L , Perea J , Perez-Alonso M , Perez-Ortin JE , Pohl TM , Prydz H , Purnelle B , Rasmussen SW , Remacha M , Revuelta JL , Rieger M , Salom D , Saluz HP , Saiz JE , Saren AM , Schafer M , Scharfe M , Schmidt ER , Schneider C , Scholler P , Schwarz S , Soler-Mira A , Urrestarazu LA , Verhasselt P , Vissers S , Voet M , Volckaert G , Wagner G , Wambutt R , Wedler E , Wedler H , Wolfl S , Harris DE , Bowman S , Brown D , Churcher CM , Connor R , Dedman K , Gentles S , Hamlin N , Hunt S , Jones L , McDonald S , Murphy L , Niblett D , Odell C , Oliver K , Rajandream MA , Richards C , Shore L , Walsh SV , Barrell BG , Dietrich FS , Mulligan J , Allen E , Araujo R , Aviles E , Berno A , Carpenter J , Chen E , Cherry JM , Chung E , Duncan M , Hunicke-Smith S , Hyman R , Komp C , Lashkari D , Lew H , Lin D , Mosedale D , Nakahara K , Namath A , Oefner P , Oh C , Petel FX , Roberts D , Schramm S , Schroeder M , Shogren T , Shroff N , Winant A , Yelton M , Botstein D , Davis RW , Johnston M , Hillier L , Riles L , Albermann K , Hani J , Heumann K , Kleine K , Mewes HW , Zollner A , Zaccaria P
Ref : Nature , 387 :75 , 1997
PubMedID: 9169867
Gene_locus related to this paper: yeast-dlhh , yeast-ECM18 , yeast-YDL109C , yeast-YDR428C , yeast-YDR444W