9gamm-b3vi58
Serratia proteamaculans Oligopeptidase B opdB
Comment
Other strains:Serratia quinivorans Serratia liquefaciens
Relationship
Family : S9N_PREPL_Peptidase_S9
Block : X
Position in NCBI Life Tree : Serratia proteamaculans
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Proteobacteria N E > Gammaproteobacteria N E > Enterobacterales N E > Yersiniaceae N E > Serratia N E > Serratia proteamaculans N EMolecular evidence
No mutation
7NE4 - E125A mutant of oligopeptidase B from S. proteomaculans with modified hinge region
7NE5 - Catalytically non active S532A mutant of oligopeptidase B from S. proteomaculans with modified hinge region
7NE7 - oligopeptidase B from S. proteomaculans with modified hinge region in complex with N-[(1S)-5-amino-1-(chloroacetyl)pentyl]-4-methylbenzenesulfonamide
7OB1 - Oligopeptidase B from S. proteamaculans with modified hinge region with spermine (replaced 6TF5 on 2022-11-02)
7YWP - Closed conformation of Oligopeptidase B from Serratia proteomaculans with covalently bound TCK
7YWS - Modified oligopeptidase B from S. proteomaculans in intermediate conformation with 3 spermine molecules at 1.7 A resolution
7YWZ - Modified oligopeptidase B from S. proteomaculans in intermediate conformation with 4 spermine molecules at 1.75 A resolution
7YX7 - Modified oligopeptidase B from S. proteomaculans in intermediate conformation with 1 spermine molecules at 1.7 A resolution
7ZJZ - Catalytically non active S532A mutant of oligopeptidase B from S. proteomaculans
8ONO - Modified oligopeptidase B from S. proteamaculans in intermediate conformation with 5 spermine molecule at 1.65 A resolution
No kinetic
No disease
Database
No Genbank
Sequence
Peptide
MTPPKAEKRP YPITTHGDTR VDDYYWLRDD ERTDPQVLDY LQAENAFTDA ALKPQQALRE TLYEEMVARE NLYFQSVPYV RHGYRYQTRF EPGNEYAIYV RQPQAESEHW DTLIDGNQRA EQREFYTLGG LEVSPDNQKL AVAEDFLSRR QYDIRFKNLS DDSWTDEVLE NTSGSFEWAN DSATVYYVRK HAKTLLPYQV YRHVVGTDPQ LDELIYEEQD DTFYVGLEKT TSDRFILIHL SSTTTSEILL LDADRADSTP QMFVPRRKDH EYGIDHYHQH FYIRSNKDGK NFGLYQSEQA DEAQWQTLIA PRIEVMLEGF SLFRDWLVVE ERSEGLTQLR QIHWQSGEVK RIAFDDPTYT TWLAYNPEPE TELLRYGYSS MTTPTTLYEL NLDSDERVML KQQEVKNFTP ENYRSERVWV KARDGVEVPV SLVYRHDSFA RGTNPLMVYG YGSYGSSMDP AFSASRLSLL DRGFVFVLAH IRGGGELGQL WYEDGKLFKK QNTFNDFIDV TEALIAQGYG DAKRVFAMGG AAGGLLMGAV INQAPELFNG IVAQVPFVDV VTTMLDESIP LTTGEYDEWG NPNQQAYYDY ILQYSPYDQV KAQDYPHMLV TTGLHDSQVQ YWEPAKWVAK LRELKTDDRQ LLLYTDMDSG HGGKSGRFKA YEDIALEYAF ILALAE
References (14)
| Title : Crystal Structure of Inhibitor-Bound Bacterial Oligopeptidase B in the Closed State: Similarity and Difference between Protozoan and Bacterial Enzymes - Petrenko_2023_Int.J.Mol.Sci_24_2286 |
| Author(s) : Petrenko DE , Karlinsky DM , Gordeeva VD , Arapidi GP , Britikova EV , Britikov VV , Nikolaeva AY , Boyko KM , Timofeev VI , Kuranova IP , Mikhailova AG , Bocharov EV , Rakitina TV |
| Ref : Int J Mol Sci , 24 : , 2023 |
| Abstract : |
| PubMedSearch : Petrenko_2023_Int.J.Mol.Sci_24_2286 |
| PubMedID: 36768612 |
| Gene_locus related to this paper: 9gamm-b3vi58 |
| Title : Elucidation of the Conformational Transition of Oligopeptidase B by an Integrative Approach Based on the Combination of X-ray, SAXS, and Essential Dynamics Sampling Simulation - Britikov_2022_Crystals_12_712 |
| Author(s) : Britikov VV , Timofeev VI , Petrenko DE , Britikova EV , Nikolaeva AY , Vlaskina AV , Boyko KM , Mikhailova AG , Rakitina TV |
| Ref : Crystals , 12 :712 , 2022 |
| Abstract : |
| PubMedSearch : Britikov_2022_Crystals_12_712 |
| PubMedID: |
| Gene_locus related to this paper: 9gamm-b3vi58 |
| Title : The Crystal Structure of Nalpha-p-tosyl-lysyl Chloromethylketone-Bound Oligopeptidase B from Serratia Proteamaculans Revealed a New Type of Inhibitor Binding. - Timofeev_2021_Crystals_11_1438 |
| Author(s) : Timofeev VI , Petrenko DE , Agapova YK , Vlaskina AV , Karlinsky DM , Mikhailova AG , Kuranova IP , Rakitina TV |
| Ref : Crystals , 11 :1438 , 2021 |
| Abstract : |
| PubMedSearch : Timofeev_2021_Crystals_11_1438 |
| PubMedID: |
| Gene_locus related to this paper: 9gamm-b3vi58 |
| Title : First Crystal Structure of Bacterial Oligopeptidase B in an Intermediate State: The Roles of the Hinge Region Modification and Spermine - Petrenko_2021_Biology.(Basel)_10_1021 |
| Author(s) : Petrenko DE , Timofeev VI , Britikov VV , Britikova EV , Kleymenov SY , Vlaskina AV , Kuranova IP , Mikhailova AG , Rakitina TV |
| Ref : Biology (Basel) , 10 : , 2021 |
| Abstract : |
| PubMedSearch : Petrenko_2021_Biology.(Basel)_10_1021 |
| PubMedID: 34681120 |
| Gene_locus related to this paper: 9gamm-b3vi58 |
| Title : Molecular dynamics complemented by site-directed mutagenesis reveals significant difference between the interdomain salt bridge networks stabilizing oligopeptidases B from bacteria and protozoa in their active conformations - Petrenko_2020_J.Biomol.Struct.Dyn_38_4868 |
| Author(s) : Petrenko DE , Mikhailova AG , Timofeev VI , Agapova Y , Karlinsky DM , Komolov AS , Korzhenevskiy DA , Vlaskina AV , Rumsh LD , Rakitina TV |
| Ref : J Biomol Struct Dyn , 38 :4868 , 2020 |
| Abstract : |
| PubMedSearch : Petrenko_2020_J.Biomol.Struct.Dyn_38_4868 |
| PubMedID: 31724904 |
| Gene_locus related to this paper: 9gamm-b3vi58 |
| Title : Crystallographic Study of Mutants and Complexes of Oligopeptidase B from Serratia proteamaculans - Petrenko_2020_Crystallogr.Rep_65_909 |
| Author(s) : Petrenko DE , Nikolaeva AY , Lazarenko VA , Dorovatovskiy PV , Timofeev VI , Vlaskina AV , Korzhenevskiy DA , Mikhailova AG , Boyko KM , Rakitina TV |
| Ref : Crystallogr Rep , 65 :909 , 2020 |
| Abstract : |
| PubMedSearch : Petrenko_2020_Crystallogr.Rep_65_909 |
| PubMedID: |
| Gene_locus related to this paper: 9gamm-b3vi58 |
| Title : Screening of Conditions that Facilitate Crystallization of Oligopeptidase B from Serratia Proteamaculans by Differential Scanning Fluorimetry - Petrenko_2020_Crystallogr.Rep_65_264 |
| Author(s) : Petrenko DE , Nikolaeva AY , Lazarenko VA , Dorovatovskii PV , Timofeev V , Vlaskina AV , Korzhenevskiy DA , Mikhailova AG , Rakitina TV |
| Ref : Crystallogr Rep , 65 :264 , 2020 |
| Abstract : |
| PubMedSearch : Petrenko_2020_Crystallogr.Rep_65_264 |
| PubMedID: |
| Gene_locus related to this paper: 9gamm-b3vi58 |
| Title : Reversible Cyclic Thermal Inactivation of Oligopeptidase B from Serratia proteamaculans - Ovchinnikova_2018_Acta.Naturae_10_65 |
| Author(s) : Ovchinnikova MV , Mikhailova AG , Karlinsky DM , Gorlenko VA , Rumsh LD |
| Ref : Acta Naturae , 10 :65 , 2018 |
| Abstract : |
| PubMedSearch : Ovchinnikova_2018_Acta.Naturae_10_65 |
| PubMedID: 30116617 |
| Gene_locus related to this paper: 9gamm-b3vi58 |
| Title : Activity modulation of the oligopeptidase B from Serratia proteamaculans by site-directed mutagenesis of amino acid residues surrounding catalytic triad histidine - Mikhailova_2017_Biochimie_139_125 |
| Author(s) : Mikhailova AG , Rakitina TV , Timofeev VI , Karlinsky DM , Korzhenevskiy DA , Agapova Ycapital Ka C , Vlaskina AV , Ovchinnikova MV , Gorlenko VA , Rumsh LD |
| Ref : Biochimie , 139 :125 , 2017 |
| Abstract : |
| PubMedSearch : Mikhailova_2017_Biochimie_139_125 |
| PubMedID: 28554571 |
| Gene_locus related to this paper: 9gamm-b3vi58 |
| Title : Truncated Variants of Serratia proteamaculans Oligopeptidase B Having Different Activities - Mikhailova_2015_Biochemistry.(Mosc)_80_1331 |
| Author(s) : Mikhailova AG , Nekrasov AN , Zinchenko AA , Rakitina TV , Korzhenevsky DA , Lipkin AV , Razguljaeva OA , Ovchinnikova MV , Gorlenko VA , Rumsh LD |
| Ref : Biochemistry (Mosc) , 80 :1331 , 2015 |
| Abstract : |
| PubMedSearch : Mikhailova_2015_Biochemistry.(Mosc)_80_1331 |
| PubMedID: 26567578 |
| Gene_locus related to this paper: 9gamm-b3vi58 |
| Title : Cloning, sequencing, expression, and characterization of thermostability of oligopeptidase B from Serratia proteamaculans, a novel psychrophilic protease - Mikhailova_2014_Protein.Expr.Purif_93_63 |
| Author(s) : Mikhailova AG , Khairullin RF , Demidyuk IV , Kostrov SV , Grinberg NV , Burova TV , Grinberg VY , Rumsh LD |
| Ref : Protein Expr Purif , 93 :63 , 2014 |
| Abstract : |
| PubMedSearch : Mikhailova_2014_Protein.Expr.Purif_93_63 |
| PubMedID: 24184401 |
| Gene_locus related to this paper: 9gamm-b3vi58 |
| Title : Oligopeptidase B from Serratia proteamaculans. III. Inhibition analysis. Specific interactions with metalloproteinase inhibitors - Mikhailova_2012_Biochemistry.(Mosc)_77_300 |
| Author(s) : Mikhailova AG , Khairullin RF , Kolomijtseva GY , Rumsh LD |
| Ref : Biochemistry (Mosc) , 77 :300 , 2012 |
| Abstract : |
| PubMedSearch : Mikhailova_2012_Biochemistry.(Mosc)_77_300 |
| PubMedID: 22803948 |
| Gene_locus related to this paper: 9gamm-b3vi58 |
| Title : Oligopeptidase B from Serratia proteamaculans. II. Enzymatic characteristics: substrate analysis, influence of calcium ions, pH and temperature dependences - Mikhailova_2011_Biochemistry.(Mosc)_76_480 |
| Author(s) : Mikhailova AG , Khairullin RF , Demidyuk IV , Gromova TY , Kostrov SV , Rumsh LD |
| Ref : Biochemistry (Mosc) , 76 :480 , 2011 |
| Abstract : |
| PubMedSearch : Mikhailova_2011_Biochemistry.(Mosc)_76_480 |
| PubMedID: 21585325 |
| Gene_locus related to this paper: 9gamm-b3vi58 |
| Title : Oligopeptidase B from Serratia proteamaculans. I. Determination of primary structure, isolation, and purification of wild-type and recombinant enzyme variants - Khairullin_2009_Biochemistry.(Mosc)_74_1164 |
| Author(s) : Khairullin RF , Mikhailova AG , Sebyakina TY , Lubenets NL , Ziganshin RH , Demidyuk IV , Gromova TY , Kostrov SV , Rumsh LD |
| Ref : Biochemistry (Mosc) , 74 :1164 , 2009 |
| Abstract : |
| PubMedSearch : Khairullin_2009_Biochemistry.(Mosc)_74_1164 |
| PubMedID: 19916930 |
| Gene_locus related to this paper: 9gamm-b3vi58 |