bactc-lipas
Bacillus thermocatenulatus triacylglycerol lipase (BTL2)
Comment
Other strains: Bacillus thermocatenulatus\; Geobacillus sp. BCO2
Relationship
Family : Bacterial_lip_FamI.5
Block : L
Position in NCBI Life Tree : Bacillus thermocatenulatus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Bacteria N E > Terrabacteria group N E > Firmicutes N E > Bacilli N E > Bacillales N E > Bacillaceae N E > Geobacillus N E > Geobacillus thermoleovorans group N E > Geobacillus thermocatenulatus N EMolecular evidence
No mutation
No kinetic
No disease
Sequence
Peptide
MMKGCRVMVV LLGLWFVFGL SVPGGRTEAA SPRANDAPIV LLHGFTGWGR EEMLGFKYWG GVRGDIEQWL NDNGYRTYTL AVGPLSSNWD RACEAYAQLV GGTVDYGAAH AAKHGHARFG RTYPGLLPEL KRGGRVHIIA HSQGGQTARM LVSLLENGSQ EEREYAKAHN VSLSPLFEGG HHFVLSVTTI ATPHDGTTLV NMVDFTDRFF DLQKAVLKAA AVASNVPYTS QVYDFKLDQW GLRRQPGESF DHYFERLKRS PVWTSTDTAR YDLSIPGAEK LNQWVQASPN TYYLSFSTER THRGALTGNY YPELGMNAFS AVVCAPFLGS YRNEALGIDD RWLENDGIVN TVSMNGPKRG SSDRIVPYDG TLKKGVWNDM GTCNVDHLEV IGVDPNPSFD IRAFYLRLAE QLASLRP
References (22)
| Title : Design of a gold nanoparticles site in an engineered lipase: an artificial metalloenzyme with enantioselective reductase-like activity - Garcia-Sanz_2024_Nanoscale__ |
| Author(s) : Garcia-Sanz C , de Las Rivas B , Palomo JM |
| Ref : Nanoscale , : , 2024 |
| Abstract : |
| PubMedSearch : Garcia-Sanz_2024_Nanoscale__ |
| PubMedID: 38501793 |
| Gene_locus related to this paper: bactc-lipas |
| Title : In silico mining and identification of a novel lipase from Paenibacillus larvae: Rational protein design for improving catalytic performance - Lu_2024_Enzyme.Microb.Technol_179_110472 |
| Author(s) : Lu M , Xu J , Wang Z , Wang Y , Wu J , Yang L |
| Ref : Enzyme Microb Technol , 179 :110472 , 2024 |
| Abstract : |
| PubMedSearch : Lu_2024_Enzyme.Microb.Technol_179_110472 |
| PubMedID: 38889604 |
| Gene_locus related to this paper: bactc-lipas , 9flao-a0a101cn99 , 9entr-a0a807lk52 , 9bacl-w2e7n6 |
| Title : In Silico and Experimental Studies on the Effect of alpha3 and alpha5 Deletion on the Biochemical Properties of Bacillus thermocatenulatus Lipase - Karkhane_2023_Mol.Biotechnol__ |
| Author(s) : Karkhane AA , Zargoosh S , Aliakbari M , Fatemi SS , Aminzadeh S , Karkhaneh B |
| Ref : Mol Biotechnol , : , 2023 |
| Abstract : |
| PubMedSearch : Karkhane_2023_Mol.Biotechnol__ |
| PubMedID: 37479905 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Understanding thermal and organic solvent stability of thermoalkalophilic lipases: insights from computational predictions and experiments - Shehata_2020_J.Mol.Model_26_122 |
| Author(s) : Shehata M , Timucin E , Venturini A , Sezerman OU |
| Ref : J Mol Model , 26 :122 , 2020 |
| Abstract : |
| PubMedSearch : Shehata_2020_J.Mol.Model_26_122 |
| PubMedID: 32383051 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Disulfide Engineered Lipase to Enhance the Catalytic Activity: A Structure-Based Approach on BTL2 - Godoy_2019_Int.J.Mol.Sci_20_ |
| Author(s) : Godoy CA , Klett J , Di Geronimo B , Hermoso JA , Guisan JM , Carrasco-Lopez C |
| Ref : Int J Mol Sci , 20 : , 2019 |
| Abstract : |
| PubMedSearch : Godoy_2019_Int.J.Mol.Sci_20_ |
| PubMedID: 31652673 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Investigating the structural properties of the active conformation BTL2 of a lipase from Geobacillus thermocatenulatus in toluene using molecular dynamic simulations and engineering BTL2 via in-silico mutation - Yenenler_2018_J.Mol.Model_24_229 |
| Author(s) : Yenenler A , Venturini A , Burduroglu HC , Sezerman OU |
| Ref : J Mol Model , 24 :229 , 2018 |
| Abstract : |
| PubMedSearch : Yenenler_2018_J.Mol.Model_24_229 |
| PubMedID: 30097767 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Study the effect of F17S mutation on the chimeric Bacillus thermocatenulatus lipase - Khaleghinejad_2016_J.Genet.Eng.Biotechnol_14_83 |
| Author(s) : Khaleghinejad SH , Motalleb G , Karkhane AA , Aminzadeh S , Yakhchali B |
| Ref : J Genet Eng Biotechnol , 14 :83 , 2016 |
| Abstract : |
| PubMedSearch : Khaleghinejad_2016_J.Genet.Eng.Biotechnol_14_83 |
| PubMedID: 30647601 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Probing the roles of two tryptophans surrounding the unique zinc coordination site in lipase family I.5 - Timucin_2016_Proteins_84_129 |
| Author(s) : Timucin E , Cousido-Siah A , Mitschler A , Podjarny A , Sezerman OU |
| Ref : Proteins , 84 :129 , 2016 |
| Abstract : |
| PubMedSearch : Timucin_2016_Proteins_84_129 |
| PubMedID: 26573720 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Engineering surface hydrophobicity improves activity of Bacillus thermocatenulatus lipase 2 enzyme - Tang_2015_Biotechnol.J_10_1762 |
| Author(s) : Tang T , Yuan C , Hwang HT , Zhao X , Ramkrishna D , Liu D , Varma A |
| Ref : Biotechnol J , 10 :1762 , 2015 |
| Abstract : |
| PubMedSearch : Tang_2015_Biotechnol.J_10_1762 |
| PubMedID: 26097135 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Zinc Modulates Self-Assembly of Bacillus thermocatenulatus Lipase - Timucin_2015_Biochemistry_54_3901 |
| Author(s) : Timucin E , Sezerman OU |
| Ref : Biochemistry , 54 :3901 , 2015 |
| Abstract : |
| PubMedSearch : Timucin_2015_Biochemistry_54_3901 |
| PubMedID: 26057387 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Optical Control of Enzyme Enantioselectivity in Solid Phase - Bautista-Barrufet_2014_ACS.Catal_4_1004 |
| Author(s) : Bautista-Barrufet A , Lopez-Gallego F , Rojas-Cervellera V , Rovira C , Pericas MA , Guisan JM , Gorostiza P |
| Ref : ACS Catal , 4 :1004 , 2014 |
| Abstract : |
| PubMedSearch : Bautista-Barrufet_2014_ACS.Catal_4_1004 |
| PubMedID: |
| Gene_locus related to this paper: bactc-lipas |
| Title : Protein Engineering of Bacillus thermocatenulatus Lipase via Deletion of the alpha5 Helix - Goodarzi_2014_Appl.Biochem.Biotechnol_174_339 |
| Author(s) : Goodarzi N , Karkhane AA , Mirlohi A , Tabandeh F , Torktas I , Aminzadeh S , Yakhchali B , Shamsara M , Ghafouri MA |
| Ref : Appl Biochem Biotechnol , 174 :339 , 2014 |
| Abstract : |
| PubMedSearch : Goodarzi_2014_Appl.Biochem.Biotechnol_174_339 |
| PubMedID: 25064134 |
| Gene_locus related to this paper: bactc-lipas |
| Title : The conserved lid tryptophan, W211, potentiates thermostability and thermoactivity in bacterial thermoalkalophilic lipases - Timucin_2013_PLoS.One_8_e85186 |
| Author(s) : Timucin E , Sezerman OU |
| Ref : PLoS ONE , 8 :e85186 , 2013 |
| Abstract : |
| PubMedSearch : Timucin_2013_PLoS.One_8_e85186 |
| PubMedID: 24391996 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Modifying the catalytic preference of tributyrin in Bacillus thermocatenulatus lipase through in-silico modeling of enzyme-substrate complex - Durmaz_2013_Protein.Eng.Des.Sel_26_325 |
| Author(s) : Durmaz E , Kuyucak S , Sezerman UO |
| Ref : Protein Engineering Des Sel , 26 :325 , 2013 |
| Abstract : |
| PubMedSearch : Durmaz_2013_Protein.Eng.Des.Sel_26_325 |
| PubMedID: 23424251 |
| Gene_locus related to this paper: bactc-lipas |
| Title : In silico and experimental characterization of chimeric Bacillus thermocatenulatus lipase with the complete conserved pentapeptide of Candida rugosa lipase - Hosseini_2013_Appl.Biochem.Biotechnol_169_773 |
| Author(s) : Hosseini M , Karkhane AA , Yakhchali B , Shamsara M , Aminzadeh S , Morshedi D , Haghbeen K , Torktaz I , Karimi E , Safari Z |
| Ref : Appl Biochem Biotechnol , 169 :773 , 2013 |
| Abstract : |
| PubMedSearch : Hosseini_2013_Appl.Biochem.Biotechnol_169_773 |
| PubMedID: 23274720 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Reactivation of a thermostable lipase by solid phase unfolding\/refolding effect of cysteine residues on refolding efficiency - Godoy_2011_Enzyme.Microb.Technol_49_388 |
| Author(s) : Godoy CA , de Las Rivas B , Bezbradica D , Bolivar JM , Lopez-Gallego F , Fernandez-Lorente G , Guisan JM |
| Ref : Enzyme Microb Technol , 49 :388 , 2011 |
| Abstract : |
| PubMedSearch : Godoy_2011_Enzyme.Microb.Technol_49_388 |
| PubMedID: 22112565 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Activation of bacterial thermoalkalophilic lipases is spurred by dramatic structural rearrangements - Carrasco-Lopez_2009_J.Biol.Chem_284_4365 |
| Author(s) : Carrasco-Lopez C , Godoy C , de Las Rivas B , Fernandez-Lorente G , Palomo JM , Guisan JM , Fernandez-Lafuente R , Martinez-Ripoll M , Hermoso JA |
| Ref : Journal of Biological Chemistry , 284 :4365 , 2009 |
| Abstract : |
| PubMedSearch : Carrasco-Lopez_2009_J.Biol.Chem_284_4365 |
| PubMedID: 19056729 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Solid-phase chemical amination of a lipase from Bacillus thermocatenulatus to improve its stabilization via covalent immobilization on highly activated glyoxyl-agarose - Fernandez-Lorente_2008_Biomacromolecules_9_2553 |
| Author(s) : Fernandez-Lorente G , Godoy CA , Mendes AA , Lopez-Gallego F , Grazu V , de Las Rivas B , Palomo JM , Hermoso J , Fernandez-Lafuente R , Guisan JM |
| Ref : Biomacromolecules , 9 :2553 , 2008 |
| Abstract : |
| PubMedSearch : Fernandez-Lorente_2008_Biomacromolecules_9_2553 |
| PubMedID: 18702542 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Crystallization and preliminary X-ray diffraction studies of the BTL2 lipase from the extremophilic microorganism Bacillus thermocatenulatus - Carrasco-Lopez_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_1043 |
| Author(s) : Carrasco-Lopez C , Godoy C , de Las Rivas B , Fernandez-Lorente G , Palomo JM , Guisan JM , Fernandez-Lafuente R , Martinez-Ripoll M , Hermoso JA |
| Ref : Acta Crystallographica Sect F Struct Biol Cryst Commun , 64 :1043 , 2008 |
| Abstract : |
| PubMedSearch : Carrasco-Lopez_2008_Acta.Crystallogr.Sect.F.Struct.Biol.Cryst.Commun_64_1043 |
| PubMedID: 18997337 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Expression, purification, and aggregation studies of His-tagged thermoalkalophilic lipase from Bacillus thermocatenulatus - Schlieben_2004_Protein.Expr.Purif_34_103 |
| Author(s) : Schlieben NH , Niefind K , Schomburg D |
| Ref : Protein Expr Purif , 34 :103 , 2004 |
| Abstract : |
| PubMedSearch : Schlieben_2004_Protein.Expr.Purif_34_103 |
| PubMedID: 14766305 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Conversion of Bacillus thermocatenulatus lipase into an efficient phospholipase with increased activity towards long-chain fatty acyl substrates by directed evolution and rational design - Kauffmann_2001_Protein.Eng_14_919 |
| Author(s) : Kauffmann I , Schmidt-Dannert C |
| Ref : Protein Engineering , 14 :919 , 2001 |
| Abstract : |
| PubMedSearch : Kauffmann_2001_Protein.Eng_14_919 |
| PubMedID: 11742112 |
| Gene_locus related to this paper: bactc-lipas |
| Title : Thermoalkalophilic lipase of Bacillus thermocatenulatus. I. molecular cloning, nucleotide sequence, purification and some properties - Schmidt-Dannert_1996_Biochim.Biophys.Acta_1301_105 |
| Author(s) : Schmidt-Dannert C , Rua ML , Atomi H , Schmid RD |
| Ref : Biochimica & Biophysica Acta , 1301 :105 , 1996 |
| Abstract : |
| PubMedSearch : Schmidt-Dannert_1996_Biochim.Biophys.Acta_1301_105 |
| PubMedID: 8652645 |
| Gene_locus related to this paper: bactc-lipas |