haein-metx

Haemophilus influenzae Homoserine O-acetyltransferase (hta)

Comment

Other strains: Haemophilus influenzae (86-028NP\; PittEE\; PittAA\; R3021\; 22.4-21\; PittHH\; PittII\; 22.1-21\; 3655\; PittGG

Relationship

Family : Homoserine_transacetylase

Block : X

Position in NCBI Life Tree : Haemophilus influenzae

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Proteobacteria N E > Gammaproteobacteria N E > Pasteurellales N E > Pasteurellaceae N E > Haemophilus N E > Haemophilus influenzae N E

Molecular evidence

No mutation

No kinetic

No disease

No substrate

No inhibitor

Sequence

Peptide

SVQNVVLFDT QPLTLMLGGK LSHINVAYQT YGTLNAEKNN AVLICHALTG DAEPYFDDGR DGWWQNFMGA GLALDTDRYF FISSNVLGGC KGTTGPSSIN PQTGKPYGSQ FPNIVVQDIV KVQKALLDHL GISHLKAIIG GSFGGMQANQ WAIDYPDFMD NIVNLCSSIY FSAEAIGFNH VMRQAVINDP NFNGGDYYEG TPPDQGLSIA RMLGMLTYRT DLQLAKAFGR ATKSDGSFWG DYFQVESYLS YQGKKFLERF DANSYLHLLR ALDMYDPSLG YDNVKEALSR IKARYTLVSV TTDQLFKPID LYKSKQLLEQ SGVDLHFYEF PSDYGHDAFL VDYDQFEKRI RDGLAGN

References (6)

Title : beta-Lactone natural products and derivatives inactivate homoserine transacetylase, a target for antimicrobial agents - De Pascale_2011_J.Antibiot.(Tokyo)_64_483
Author(s) : De Pascale G , Nazi I , Harrison PH , Wright GD
Ref : J Antibiot (Tokyo) , 64 :483 , 2011
PubMedID: 21522158
Gene_locus related to this paper: haein-metx

Title : Characterization and modeling of the Haemophilus influenzae core and supragenomes based on the complete genomic sequences of Rd and 12 clinical nontypeable strains - Hogg_2007_Genome.Biol_8_R103
Author(s) : Hogg JS , Hu FZ , Janto B , Boissy R , Hayes J , Keefe R , Post JC , Ehrlich GD
Ref : Genome Biol , 8 :R103 , 2007
PubMedID: 17550610
Gene_locus related to this paper: haei8-q4qkr2 , haeif-a4n6l8 , haeif-a4nfi4 , haein-metx , haein-sfgh , haein-y1552 , haein-yfbb

Title : Genomic sequence of an otitis media isolate of nontypeable Haemophilus influenzae: comparative study with H. influenzae serotype d, strain KW20 - Harrison_2005_J.Bacteriol_187_4627
Author(s) : Harrison A , Dyer DW , Gillaspy A , Ray WC , Mungur R , Carson MB , Zhong H , Gipson J , Gipson M , Johnson LS , Lewis L , Bakaletz LO , Munson RS, Jr.
Ref : Journal of Bacteriology , 187 :4627 , 2005
PubMedID: 15968074
Gene_locus related to this paper: haei8-q4qkr2 , haein-HI0193 , haein-metx , haein-pldb , haein-sfgh , haein-yfbb

Title : Crystal structure of homoserine transacetylase from Haemophilus influenzae reveals a new family of alpha\/beta-hydrolases - Mirza_2005_Biochemistry_44_15768
Author(s) : Mirza IA , Nazi I , Korczynska M , Wright GD , Berghuis AM
Ref : Biochemistry , 44 :15768 , 2005
PubMedID: 16313180
Gene_locus related to this paper: haein-metx

Title : Enzyme-catalyzed acylation of homoserine: mechanistic characterization of the Haemophilus influenzae met2-encoded homoserine transacetylase - Born_2000_Biochemistry_39_8556
Author(s) : Born TL , Franklin M , Blanchard JS
Ref : Biochemistry , 39 :8556 , 2000
PubMedID: 10913262
Gene_locus related to this paper: haein-metx