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human-TEX30

Homo sapiens (Human) testis expressed 30 Tex30 C13orf27 chromosome 13

Comment

previously CM027_HUMAN human-Q96KZ8, similar to riken cdna 1700029f09 gene. Testis-expressed 30 (Tex30) mRNA expression is induced by the germ-cell-specific transcription factors MEIOSIN and stimulated by retinoic acid during meiotic prophase and is further upregulated in round spermatids. TEX30 protein is detected predominantly in the cytoplasm of step 16 spermatids, where it is highly enriched in the cytoplasmic lobe that is normally discarded as the residual body during spermiation

Relationship

Family : NLS3-Tex30

Block : X

Position in NCBI Life Tree : Homo sapiens

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Primates N E > Haplorrhini N E > Simiiformes N E > Catarrhini N E > Hominoidea N E > Hominidae N E > Homininae N E > Homo N E > Homo sapiens N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MSHTEVKLKI PFGNKLLDAV CLVPNKSLTY GIILTHGASG DMNLPHLMSL ASHLASHGFF CLRFTCKGLN IVHRIKAYKS VLNYLKTSGE YKLAGVFLGG RSMGSRAAAS VMCHIEPDDG DDFVRGLICI SYPLHHPKQQ HKLRDEDLFR LKEPVLFVSG SADEMCEKNL LEKVAQKMQA PHKIHWIEKA NHSMAVKGRS TNDVFKEINT QILFWIQEIT EMDKKCH

References (2)

Title : TEX30 safeguards sperm morphogenesis and quality consistency required for male fertility - Kikuchi_2026_Reproduction_171_xaag022
Author(s) : Kikuchi K , Iisaka S , Uriu R , Shinohara H , Ezaki A , Shimada R , Fujimura S , Tani N , Araki K , Noda T , Ishiguro KI
Ref : Reproduction , 171 : , 2026
Abstract :
PubMedSearch : Kikuchi_2026_Reproduction_171_xaag022
PubMedID: 41689187
Gene_locus related to this paper: human-TEX30 , mouse-Tex30

Title : The DNA sequence and analysis of human chromosome 13 - Dunham_2004_Nature_428_522
Author(s) : Dunham A , Matthews LH , Burton J , Ashurst JL , Howe KL , Ashcroft KJ , Beare DM , Burford DC , Hunt SE , Griffiths-Jones S , Jones MC , Keenan SJ , Oliver K , Scott CE , Ainscough R , Almeida JP , Ambrose KD , Andrews DT , Ashwell RI , Babbage AK , Bagguley CL , Bailey J , Bannerjee R , Barlow KF , Bates K , Beasley H , Bird CP , Bray-Allen S , Brown AJ , Brown JY , Burrill W , Carder C , Carter NP , Chapman JC , Clamp ME , Clark SY , Clarke G , Clee CM , Clegg SC , Cobley V , Collins JE , Corby N , Coville GJ , Deloukas P , Dhami P , Dunham I , Dunn M , Earthrowl ME , Ellington AG , Faulkner L , Frankish AG , Frankland J , French L , Garner P , Garnett J , Gilbert JG , Gilson CJ , Ghori J , Grafham DV , Gribble SM , Griffiths C , Hall RE , Hammond S , Harley JL , Hart EA , Heath PD , Howden PJ , Huckle EJ , Hunt PJ , Hunt AR , Johnson C , Johnson D , Kay M , Kimberley AM , King A , Laird GK , Langford CJ , Lawlor S , Leongamornlert DA , Lloyd DM , Lloyd C , Loveland JE , Lovell J , Martin S , Mashreghi-Mohammadi M , McLaren SJ , McMurray A , Milne S , Moore MJ , Nickerson T , Palmer SA , Pearce AV , Peck AI , Pelan S , Phillimore B , Porter KM , Rice CM , Searle S , Sehra HK , Shownkeen R , Skuce CD , Smith M , Steward CA , Sycamore N , Tester J , Thomas DW , Tracey A , Tromans A , Tubby B , Wall M , Wallis JM , West AP , Whitehead SL , Willey DL , Wilming L , Wray PW , Wright MW , Young L , Coulson A , Durbin R , Hubbard T , Sulston JE , Beck S , Bentley DR , Rogers J , Ross MT
Ref : Nature , 428 :522 , 2004
Abstract :
PubMedSearch : Dunham_2004_Nature_428_522
PubMedID: 15057823
Gene_locus related to this paper: human-ESD , human-TEX30