Acephate

"Acephate is found in a variety of commercial insecticides. Trade names for products containing acephate include Orthene, Asataf, Pillarthene, Kitron, Aimthane, Ortran, Ortho 12420, Ortril, Chrevron RE 12420, and Orthene 755"

General

Type : Insecticide,Organophosphate,Sulfur Compound

Chemical_Nomenclature : N-[methoxy(methylsulfanyl)phosphoryl]acetamide

Canonical SMILES : CC(=O)NP(=O)(OC)SC

InChI : InChI=1S\/C4H10NO3PS\/c1-4(6)5-9(7,8-2)10-3\/h1-3H3,(H,5,6,7)

InChIKey : YASYVMFAVPKPKE-UHFFFAOYSA-N

Other name(s) : O,S-dimethyl acetylphos-phoramidothioate (IUPAC) (1, 3),O,S-dimethyl acetic phosphoramidothioate,(7) N-[methoxy(methylthio)phosphinoyl] acetamide,Acetamidophos,Orthene,Ortran,Ortril,Chevron Orthene,Orthene-755,Caswell No. 002A


MW : 183.17

Formula : C4H10NO3PS

CAS_number : 30560-19-1

PubChem : 1982

UniChem : YASYVMFAVPKPKE-UHFFFAOYSA-N

IUPHAR :

Wikipedia : Acephate

Target

Families : Acephate ligand of proteins in family: ACHE

Stucture :

Protein :

References (12)

Title : Extremely sensitive biomarker of acute organophosphorus insecticide exposure - Fujikawa_2005_Hum.Exp.Toxicol_24_333
Author(s) : Fujikawa Y , Satoh T , Suganuma A , Suzuki S , Niikura Y , Yui S , Yamaura Y
Ref : Hum Exp Toxicol , 24 :333 , 2005
Abstract : Fujikawa_2005_Hum.Exp.Toxicol_24_333
ESTHER : Fujikawa_2005_Hum.Exp.Toxicol_24_333
PubMedSearch : Fujikawa_2005_Hum.Exp.Toxicol_24_333
PubMedID: 16004201
Gene_locus related to this paper: human-CES1 , mouse-Ces1e , ratno-Ces1e

Title : Mechanisms of insecticide resistance in the aphid Nasonovia ribisnigri (Mosley) (Homoptera: Aphididae) from France - Rufingier_1999_Insect.Biochem.Mol.Biol_29_385
Author(s) : Rufingier C , Pasteur N , Lagnel J , Martin C , Navajas M
Ref : Insect Biochemistry & Molecular Biology , 29 :385 , 1999
Abstract : Rufingier_1999_Insect.Biochem.Mol.Biol_29_385
ESTHER : Rufingier_1999_Insect.Biochem.Mol.Biol_29_385
PubMedSearch : Rufingier_1999_Insect.Biochem.Mol.Biol_29_385
PubMedID: 10333576

Title : Role of oxidant stress and antioxidant protection in acephate-induced renal tubular cytotoxicity - Poovala_1998_Toxicol.Sci_46_403
Author(s) : Poovala VS , Kanji VK , Tachikawa H , Salahudeen AK
Ref : Toxicol Sci , 46 :403 , 1998
Abstract : Poovala_1998_Toxicol.Sci_46_403
ESTHER : Poovala_1998_Toxicol.Sci_46_403
PubMedSearch : Poovala_1998_Toxicol.Sci_46_403
PubMedID: 10048144

Title : Physicochemical, molecular-orbital and electronic properties of acephate and methamidophos - Singh_1998_Comp.Biochem.Physiol.C.Pharmacol.Toxicol.Endocrinol_119_107
Author(s) : Singh AK , White T , Spassova D , Jiang Y
Ref : Comparative Biochemistry & Physiology C Pharmacology Toxicology & Endocrinology , 119 :107 , 1998
Abstract : Singh_1998_Comp.Biochem.Physiol.C.Pharmacol.Toxicol.Endocrinol_119_107
ESTHER : Singh_1998_Comp.Biochem.Physiol.C.Pharmacol.Toxicol.Endocrinol_119_107
PubMedSearch : Singh_1998_Comp.Biochem.Physiol.C.Pharmacol.Toxicol.Endocrinol_119_107
PubMedID: 9568380

Title : Augmented hydrolysis of diisopropyl fluorophosphate in engineered mutants of phosphotriesterase - Watkins_1997_J.Biol.Chem_272_25596
Author(s) : Watkins LM , Mahoney HJ , McCulloch JK , Raushel FM
Ref : Journal of Biological Chemistry , 272 :25596 , 1997
Abstract : Watkins_1997_J.Biol.Chem_272_25596
ESTHER : Watkins_1997_J.Biol.Chem_272_25596
PubMedSearch : Watkins_1997_J.Biol.Chem_272_25596
PubMedID: 9325279

Title : Residues and half-lives of acephate, methamidophos, and pirimiphos- methyl in leaves and fruit of greenhouse-grown tomatoes -
Author(s) : Antonious GF , Snyder JC
Ref : Bulletin of Environmental Contamination & Toxicology , 52 :141 , 1994
PubMedID: 8130409

Title : Safety\/risk assessment of pesticides: principles, procedures and examples - Lu_1992_Toxicol.Lett_64_783
Author(s) : Lu FC , Dourson ML
Ref : Toxicol Lett , 64-65 :783 , 1992
Abstract : Lu_1992_Toxicol.Lett_64_783
ESTHER : Lu_1992_Toxicol.Lett_64_783
PubMedSearch : Lu_1992_Toxicol.Lett_64_783
PubMedID: 1471237

Title : Confirmation method for the identification and determination of some organophosphorus and organochlorine pesticides in cocoa beans by gas chromatography-mass spectrometry - Rodriguez_1991_J.Chromatogr_562_547
Author(s) : Rodriguez P , Permanyer J , Grases JM , Gonzalez C
Ref : Journal of Chromatography , 562 :547 , 1991
Abstract : Rodriguez_1991_J.Chromatogr_562_547
ESTHER : Rodriguez_1991_J.Chromatogr_562_547
PubMedSearch : Rodriguez_1991_J.Chromatogr_562_547
PubMedID: 2026717

Title : Molecular properties and inhibition kinetics of acetylcholinesterase obtained from rat brain and cockroach ganglion - Singh_1990_Toxicol.Ind.Health_6_551
Author(s) : Singh AK
Ref : Toxicol Ind Health , 6 :551 , 1990
Abstract : Singh_1990_Toxicol.Ind.Health_6_551
ESTHER : Singh_1990_Toxicol.Ind.Health_6_551
PubMedSearch : Singh_1990_Toxicol.Ind.Health_6_551
PubMedID: 2097819

Title : Studies on the toxicity, metabolism, and anticholinesterase properties of acephate and methamidophos - Hussain_1985_J.Env.Sci.Health_20_129
Author(s) : Hussain MA , Mohamad RB , Oloffs PC
Ref : Journal of Environmental Science & Health Part B: Pesticides, Food Contaminants, & Agricultural Wastes , 20 :129 , 1985
Abstract : Hussain_1985_J.Env.Sci.Health_20_129
ESTHER : Hussain_1985_J.Env.Sci.Health_20_129
PubMedSearch : Hussain_1985_J.Env.Sci.Health_20_129
PubMedID: 3989221

Title : Toxicological properties of trialkyl phosphorothioate and dialkyl alkyl- and arylphosphonothioate esters - Fukuto_1983_J.Environ.Sci.Health.B_18_89
Author(s) : Fukuto TR
Ref : J Environ Sci Health B , 18 :89 , 1983
Abstract : Fukuto_1983_J.Environ.Sci.Health.B_18_89
ESTHER : Fukuto_1983_J.Environ.Sci.Health.B_18_89
PubMedSearch : Fukuto_1983_J.Environ.Sci.Health.B_18_89
PubMedID: 6833715

Title : Inhibitory effect of acephate (N-acetyl O, S-dimethyl thiophosphoramide) on serum cholinesterase--effect of acephate on cholinesterase - Ando_1982_J.Toxicol.Sci_7_185
Author(s) : Ando M , Wakamatsu K
Ref : Journal of Toxicological Sciences , 7 :185 , 1982
Abstract : Ando_1982_J.Toxicol.Sci_7_185
ESTHER : Ando_1982_J.Toxicol.Sci_7_185
PubMedSearch : Ando_1982_J.Toxicol.Sci_7_185
PubMedID: 7154130