mouse-Ces1e

Mus musculus esterase-22 (egasyn) Es-22 E.R.-targeting prot. of beta-glucuronidase

Comment

ES22_MOUSE was renamed to EST1E_MOUSE in release

Relationship

Family : Carb_B_Chordata

Block : C

Position in NCBI Life Tree : Mus musculus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Rodentia N E > Myomorpha N E > Muroidea N E > Muridae N E > Murinae N E > Mus [genus] N E > Mus [subgenus] N E > Mus musculus N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MCLSALILVS LAAFTAGAGH PSSPPMVDTV QGKVLGKYIS LEGFTQPVAV FLGVPFAKPP LGSLRFAPPQ PAEPWSSVKN ATSYPPMCFQ DPVTGQIVND LLTNRKEKIP LQFSEDCLYL NIYTPADLTK SDRLPVMVWI HGGGLVLGGA STYDGLVLST HENVVVVVIQ YRLGIWGFFS TGDEHSRGNW GHLDQVAALH WVQDNIAKFG GDPGSVTIFG ESAGGESVSV LVLSPLAKNL FQRAISESGV ALTAGLVKKN TRPLAEKIAV ISGCKNTTSA AMVHCLRQKT EEELLGTTLK LNLFKLDLHG DSRQSHPFVP TVLDGVLLPK MPEEILAEKN FNTVPYIVGI NKQEFGWILP TMMNYPPSDV KLDQMTAMSL LKKSSFLLNL PEDAIAVAIE KYLRDKDYTG RNKDQLLELI GDVVFGVPSV IVSRGHRDAG APTYMYEFQY SPSFSSEMKP DTVVGDHGDE IYSVFGAPIL RGGTSEEEIN LSKMMMKFWA NFARNGNPNG QGLPHWPEYD QKEGYLQIGA TTQQAQKLKE KEVAFWTELL AKKQLPTEHT EL

References (7)

Title : Natural deletion of mouse carboxylesterases Ces1c\/d\/e impacts drug metabolism and metabolic syndrome development - Gan_2023_Biomed.Pharmacother_164_114956
Author(s) : Gan C , Wang J , Wang Y , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Lebre MC , Wagenaar E , Rosing H , Klarenbeek S , Bleijerveld OB , Song JY , Altelaar M , Beijnen JH , Schinkel AH
Ref : Biomed Pharmacother , 164 :114956 , 2023
PubMedID: 37267638
Gene_locus related to this paper: human-CES1 , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e

Title : Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism - Gan_2023_Acta.Pharm.Sin.B_13_618
Author(s) : Gan C , Wang J , Martinez-Chavez A , Hillebrand M , de Vries N , Beukers J , Wagenaar E , Wang Y , Lebre MC , Rosing H , Klarenbeek S , Ali RB , Pritchard C , Huijbers I , Beijnen JH , Schinkel AH
Ref : Acta Pharm Sin B , 13 :618 , 2023
PubMedID: 36873183
Gene_locus related to this paper: mouse-Ces1a , mouse-Ces1b , mouse-Ces1c , mouse-Ces1d , mouse-Ces1e , mouse-Ces1f , mouse-Ces1g , mouse-Ces1h

Title : Extremely sensitive biomarker of acute organophosphorus insecticide exposure - Fujikawa_2005_Hum.Exp.Toxicol_24_333
Author(s) : Fujikawa Y , Satoh T , Suganuma A , Suzuki S , Niikura Y , Yui S , Yamaura Y
Ref : Hum Exp Toxicol , 24 :333 , 2005
PubMedID: 16004201
Gene_locus related to this paper: human-CES1 , mouse-Ces1e , ratno-Ces1e

Title : Toxicological significance in the cleavage of esterase-beta-glucuronidase complex in liver microsomes by organophosphorus compounds - Satoh_1999_Chem.Biol.Interact_119-120_471
Author(s) : Satoh T , Suzuki S , Kawai N , Nakamura T , Hosokawa M
Ref : Chemico-Biological Interactions , 119-120 :471 , 1999
PubMedID: 10421485
Gene_locus related to this paper: mouse-Ces1e

Title : Characterization and functional expression of a cDNA encoding egasyn (esterase-22): the endoplasmic reticulum-targeting protein of beta- glucuronidase - Ovnic_1991_Genomics_11_956
Author(s) : Ovnic M , Swank RT , Fletcher C , Zhen L , Novak EK , Baumann H , Heintz N , Ganschow RE
Ref : Genomics , 11 :956 , 1991
PubMedID: 1783403
Gene_locus related to this paper: mouse-Ces1e

Title : An accessory protein identical to mouse egasyn is complexed with rat microsomal beta-glucuronidase and is identical to rat esterase-3 - Medda_1987_J.Biol.Chem_262_7248
Author(s) : Medda S , Takeuchi K , Devore-Carter D , von Deimling O , Heymann E , Swank RT
Ref : Journal of Biological Chemistry , 262 :7248 , 1987
PubMedID: 3294829
Gene_locus related to this paper: mouse-Ces1e , ratno-Ces1e