Benzyloxy-benzylamino-Carltonine-Cpd28
hBChE IC50 = 0.171 +/- 0.063 microM
General
Type : Natural_modified
Chemical_Nomenclature : 4-[2-({[4-(Benzyloxy)phenyl]methyl}amino)ethyl]phenol
Canonical SMILES : C1=CC=CC(=C1)COC2=CC=C(C=C2)CNCCC3=CC=C(C=C3)O
InChI : InChI=1S\/C22H23NO2\/c24-21-10-6-18(7-11-21)14-15-23-16-19-8-12-22(13-9-19)25-17-20-4-2-1-3-5-20\/h1-13,23-24H,14-17H2
InChIKey : MCTMTEDRYZVOOJ-UHFFFAOYSA-N
Other name(s) :
Target
Families : Benzyloxy-benzylamino-Carltonine-Cpd28 ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : Carltonine-Derived Compounds for Targeted Butyrylcholinesterase Inhibition - Pidany_2024_RSC.Med.Chem_15_1601 |
| Author(s) : Pidany F , Kroustkova J , Jenco J , Breiterova K , Muckovab L , Novakova L , Kunes J , Fibigar J , Kucera T , Novak M , Sorf A , Hrabinova M , Pulkrabkova L , Janousek J , Soukup O , Jun D , Korabecny J , Cahlikova L |
| Ref : RSC Med Chem , 15 :1601 , 2024 |
| Abstract : |
| PubMedSearch : Pidany_2024_RSC.Med.Chem_15_1601 |
| PubMedID: 38784455 |
| Gene_locus related to this paper: human-BCHE |