Benzyloxy-benzylamino-Carltonine-Cpd33
hBChE IC50 = 0.167 +/- 0.018 microM
General
Type : Natural_modified
Chemical_Nomenclature : 4-[2-({[4-(Benzyloxy)phenyl]methyl}(propyl)amino)ethyl]phenol
Canonical SMILES : C1=CC=CC(=C1)COC2=CC=C(C=C2)CN(CCC3=CC=C(C=C3)O)CCC
InChI : InChI=1S\/C25H29NO2\/c1-2-17-26(18-16-21-8-12-24(27)13-9-21)19-22-10-14-25(15-11-22)28-20-23-6-4-3-5-7-23\/h3-15,27H,2,16-20H2,1H3
InChIKey : YMQIIHDPGYQULF-UHFFFAOYSA-N
Other name(s) :
Target
Families : Benzyloxy-benzylamino-Carltonine-Cpd33 ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : Carltonine-Derived Compounds for Targeted Butyrylcholinesterase Inhibition - Pidany_2024_RSC.Med.Chem_15_1601 |
| Author(s) : Pidany F , Kroustkova J , Jenco J , Breiterova K , Muckovab L , Novakova L , Kunes J , Fibigar J , Kucera T , Novak M , Sorf A , Hrabinova M , Pulkrabkova L , Janousek J , Soukup O , Jun D , Korabecny J , Cahlikova L |
| Ref : RSC Med Chem , 15 :1601 , 2024 |
| Abstract : |
| PubMedSearch : Pidany_2024_RSC.Med.Chem_15_1601 |
| PubMedID: 38784455 |
| Gene_locus related to this paper: human-BCHE |