mimics the Monoacylglycerol MAG of identical size (here the 1-myristoylglycerol Monomyristin (C14:0)). The adduct on the active serine lacks the leaving group 4-nitrophenol
Type : Organophosphate, pNP, Analogue of substrate, Lipase inhibitor, Azido
Chemical_Nomenclature : 3-[dodecoxy(hydroxy)phosphoryl]propylimino-iminoazanium
Canonical SMILES : CCCCCCCCCCCCOP(=O)(CCCN=[N+]=N)O
InChI : InChI=1S\/C15H32N3O3P\/c1-2-3-4-5-6-7-8-9-10-11-14-21-22(19,20)15-12-13-17-18-16\/h16H,2-15H2,1H3\/p+1
InChIKey : BEUWZXAEJRVUSA-UHFFFAOYSA-O
Other name(s) : dodecyl 4-nitrophenyl (3-azidopropyl)phosphonate || Dodecyl Hydrogen (S)-(3-Azidopropyl)phosphonate || 1QX
MW : 334.42 || 454,50
Formula : C15H33N3O3P+ || C21H35N4O5P
CAS_number :
PubChem : 71710907
UniChem : BEUWZXAEJRVUSA-UHFFFAOYSA-O
Families : C12-myristoyl-MAG-like-phosphonate ligand of proteins in family
CarbLipBact_2
Structure :
4KE7
Protein :
bac25-mglp
Title : Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase - Rengachari_2013_J.Biol.Chem_288_31093 |
Author(s) : Rengachari S , Aschauer P , Schittmayer M , Mayer N , Gruber K , Breinbauer R , Birner-Gruenberger R , Dreveny I , Oberer M |
Ref : Journal of Biological Chemistry , 288 :31093 , 2013 |
Abstract : |
PubMedSearch : Rengachari_2013_J.Biol.Chem_288_31093 |
PubMedID: 24014019 |
Gene_locus related to this paper: bac25-mglp |