Title : Unmasking Crucial Residues in Adipose Triglyceride Lipase (ATGL) for Co-Activation with Comparative Gene Identification-58 (CGI-58) - Kulminskaya_2023_J.Lipid.Res__100491 |
Author(s) : Kulminskaya N , Rodriguez Gamez CF , Hofer P , Cerk IK , Dubey N , Viertlmayr R , Sagmeister T , Pavkov-Keller T , Zechner R , Oberer M |
Ref : J Lipid Res , :100491 , 2023 |
Abstract : |
PubMedSearch : Kulminskaya_2023_J.Lipid.Res__100491 |
PubMedID: 38135254 |
Gene_locus related to this paper: human-ABHD5 , mouse-abhd5 |
Title : PNPLA-mediated lipid hydrolysis and transacylation - At the intersection of catabolism and anabolism - Colaco-Gaspar_2023_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids__159410 |
Author(s) : Colaco-Gaspar M , Hofer P , Oberer M , Zechner R |
Ref : Biochimica & Biophysica Acta Molecular & Cellular Biology Lipids , :159410 , 2023 |
Abstract : |
PubMedSearch : Colaco-Gaspar_2023_Biochim.Biophys.Acta.Mol.Cell.Biol.Lipids__159410 |
PubMedID: 37951382 |
Title : The Potential Roles of Transacylation in Intracellular Lipolysis and Related Qssa Approximations - Elias_2023_Bull.Math.Biol_85_82 |
Author(s) : Elias J , Fellner K , Hofer P , Oberer M , Schreiber R , Zechner R |
Ref : Bull Math Biol , 85 :82 , 2023 |
Abstract : |
PubMedSearch : Elias_2023_Bull.Math.Biol_85_82 |
PubMedID: 37544001 |
Title : The Crystal Structure of Mouse Ces2c, a Potential Ortholog of Human CES2, Shows Structural Similarities in Substrate Regulation and Product Release to Human CES1 - Eisner_2022_Int.J.Mol.Sci_23_13101 |
Author(s) : Eisner H , Riegler-Berket L , Gamez CFR , Sagmeister T , Chalhoub G , Darnhofer B , Jazleena PJ , Birner-Gruenberger R , Pavkov-Keller T , Haemmerle G , Schoiswohl G , Oberer M |
Ref : Int J Mol Sci , 23 : , 2022 |
Abstract : |
PubMedSearch : Eisner_2022_Int.J.Mol.Sci_23_13101 |
PubMedID: 36361897 |
Gene_locus related to this paper: mouse-Ces2c |
Title : Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes - Grabner_2022_J.Am.Chem.Soc__ |
Author(s) : Grabner GF , Guttenberger N , Mayer N , Migglautsch-Sulzer AK , Lembacher-Fadum C , Fawzy N , Bulfon D , Hofer P , Zullig T , Hartig L , Kulminskaya N , Chalhoub G , Schratter M , Radner FPW , Preiss-Landl K , Masser S , Lass A , Zechner R , Gruber K , Oberer M , Breinbauer R , Zimmermann R |
Ref : Journal of the American Chemical Society , : , 2022 |
Abstract : |
PubMedSearch : Grabner_2022_J.Am.Chem.Soc__ |
PubMedID: 35362954 |
Title : alpha\/beta-Hydrolase Domain-Containing 6 (ABHD6)- A Multifunctional Lipid Hydrolase - Pusch_2022_Metabolites_12_761 |
Author(s) : Pusch LM , Riegler-Berket L , Oberer M , Zimmermann R , Taschler U |
Ref : Metabolites , 12 : , 2022 |
Abstract : |
PubMedSearch : Pusch_2022_Metabolites_12_761 |
PubMedID: 36005632 |
Gene_locus related to this paper: human-ABHD6 |
Title : Optimized expression and purification of adipose triglyceride lipase improved hydrolysis and transacylation catalytic activities in vitro - Kulminskaya_2021_J.Biol.Chem__101206 |
Author(s) : Kulminskaya N , Radler C , Viertlmayr R , Heier C , Hofer P , Colaco-Gaspar M , Owens RJ , Zimmermann R , Schreiber R , Zechner R , Oberer M |
Ref : Journal of Biological Chemistry , :101206 , 2021 |
Abstract : |
PubMedSearch : Kulminskaya_2021_J.Biol.Chem__101206 |
PubMedID: 34543623 |
Title : Carboxylesterase 2 proteins are efficient diglyceride and monoglyceride lipases possibly implicated in metabolic disease - Chalhoub_2021_J.Lipid.Res__100075 |
Author(s) : Chalhoub G , Kolleritsch S , Maresch LK , Taschler U , Pajed L , Tilp A , Natmessnig H , Rosina P , Kien B , Radner FPW , Schicho R , Oberer M , Schoiswohl G , Haemmerle G |
Ref : J Lipid Res , :100075 , 2021 |
Abstract : |
PubMedSearch : Chalhoub_2021_J.Lipid.Res__100075 |
PubMedID: 33872605 |
Gene_locus related to this paper: human-CES2 , mouse-Ces2a , mouse-Ces2b , mouse-Ces2c |
Title : Structural Changes in the Cap of Rv0183\/mtbMGL Modulate the Shape of the Binding Pocket - Grininger_2021_Biomolecules_11_1299 |
Author(s) : Grininger C , Leypold M , Aschauer P , Pavkov-Keller T , Riegler-Berket L , Breinbauer R , Oberer M |
Ref : Biomolecules , 11 :1299 , 2021 |
Abstract : |
PubMedSearch : Grininger_2021_Biomolecules_11_1299 |
PubMedID: 34572512 |
Gene_locus related to this paper: myctu-rv0183 |
Title : Protein-protein interactions regulate the activity of Adipose Triglyceride Lipase in intracellular lipolysis - Kulminskaya_2020_Biochimie_169_62 |
Author(s) : Kulminskaya N , Oberer M |
Ref : Biochimie , 169 :62 , 2020 |
Abstract : |
PubMedSearch : Kulminskaya_2020_Biochimie_169_62 |
PubMedID: 31404588 |
Title : The alpha\/beta-hydrolase domain-containing 4- and 5-related phospholipase Pummelig controls energy storage in Drosophila - Hehlert_2019_J.Lipid.Res_60_1365 |
Author(s) : Hehlert P , Hofferek V , Heier C , Eichmann TO , Riedel D , Rosenberg J , Takacs A , Nagy HM , Oberer M , Zimmermann R , Kuhnlein RP |
Ref : J Lipid Res , 60 :1365 , 2019 |
Abstract : |
PubMedSearch : Hehlert_2019_J.Lipid.Res_60_1365 |
PubMedID: 31164391 |
Gene_locus related to this paper: drome-CG1882 |
Title : The lipid droplet-associated protein ABHD5 protects the heart through proteolysis of HDAC4 - Jebessa_2019_Nat.Metab_1_1157 |
Author(s) : Jebessa ZH , Shanmukha Kumar D , Dewenter M , Lehmann LH , Xu C , Schreiter F , Siede D , Gong XM , Worst BC , Federico G , Sauer SW , Fischer T , Wechselberger L , Muller OJ , Sossalla S , Dieterich C , Most P , Grone HJ , Moro C , Oberer M , Haemmerle G , Katus HA , Tyedmers J , Backs J |
Ref : Nat Metab , 1 :1157 , 2019 |
Abstract : |
PubMedSearch : Jebessa_2019_Nat.Metab_1_1157 |
PubMedID: 31742248 |
Gene_locus related to this paper: human-ABHD5 |
Title : Hypoxia-inducible lipid droplet-associated protein inhibits adipose triglyceride lipase - Padmanabha_2018_J.Lipid.Res_59_531 |
Author(s) : Padmanabha Das KM , Wechselberger L , Liziczai M , De la Rosa Rodriguez M , Grabner GF , Heier C , Viertlmayr R , Radler C , Lichtenegger J , Zimmermann R , Borst JW , Zechner R , Kersten S , Oberer M |
Ref : J Lipid Res , 59 :531 , 2018 |
Abstract : |
PubMedSearch : Padmanabha_2018_J.Lipid.Res_59_531 |
PubMedID: 29326160 |
Title : Identification of lipases with activity towards monoacylglycerol by criterion of conserved cap architectures - Riegler-Berket_2018_Biochim.Biophys.Acta_1863_679 |
Author(s) : Riegler-Berket L , Leitmeier A , Aschauer P , Dreveny I , Oberer M |
Ref : Biochimica & Biophysica Acta , 1863 :679 , 2018 |
Abstract : |
PubMedSearch : Riegler-Berket_2018_Biochim.Biophys.Acta_1863_679 |
PubMedID: 29627382 |
Gene_locus related to this paper: 9bact-TtEst , agrvs-b9jym4 , bac25-mglp , bacsu-cbxnp , human-MGLL , symth-q67mr3 , vibch-VC1974 , yeast-mgll |
Title : The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition - Aschauer_2018_Sci.Rep_8_8948 |
Author(s) : Aschauer P , Zimmermann R , Breinbauer R , Pavkov-Keller T , Oberer M |
Ref : Sci Rep , 8 :8948 , 2018 |
Abstract : |
PubMedSearch : Aschauer_2018_Sci.Rep_8_8948 |
PubMedID: 29895832 |
Gene_locus related to this paper: myctu-rv0183 |
Title : Adipose Triglyceride Lipase Regulation: An Overview - Cerk_2018_Curr.Protein.Pept.Sci_19_221 |
Author(s) : Cerk IK , Wechselberger L , Oberer M |
Ref : Curr Protein Pept Sci , 19 :221 , 2018 |
Abstract : |
PubMedSearch : Cerk_2018_Curr.Protein.Pept.Sci_19_221 |
PubMedID: 28925902 |
Title : Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p - Aschauer_2016_Biochim.Biophys.Acta_1861_462 |
Author(s) : Aschauer P , Rengachari S , Lichtenegger J , Schittmayer M , Das KM , Mayer N , Breinbauer R , Birner-Gruenberger R , Gruber CC , Zimmermann R , Gruber K , Oberer M |
Ref : Biochimica & Biophysica Acta , 1861 :462 , 2016 |
Abstract : |
PubMedSearch : Aschauer_2016_Biochim.Biophys.Acta_1861_462 |
PubMedID: 26869448 |
Gene_locus related to this paper: yeast-mgll |
Title : Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism - Heier_2016_J.Biol.Chem_291_11865 |
Author(s) : Heier C , Taschler U , Radulovic M , Aschauer P , Eichmann TO , Grond S , Wolinski H , Oberer M , Zechner R , Kohlwein SD , Zimmermann R |
Ref : Journal of Biological Chemistry , 291 :11865 , 2016 |
Abstract : |
PubMedSearch : Heier_2016_J.Biol.Chem_291_11865 |
PubMedID: 27036938 |
Title : GPIHBP1 missense mutations often cause multimerization of GPIHBP1 and thereby prevent lipoprotein lipase binding - Beigneux_2015_Circ.Res_116_624 |
Author(s) : Beigneux AP , Fong LG , Bensadoun A , Davies BS , Oberer M , Gardsvoll H , Ploug M , Young SG |
Ref : Circulation Research , 116 :624 , 2015 |
Abstract : |
PubMedSearch : Beigneux_2015_Circ.Res_116_624 |
PubMedID: 25387803 |
Title : Structure of a CGI-58 Motif Provides the Molecular Basis of Lipid Droplet Anchoring - Boeszoermenyi_2015_J.Biol.Chem_290_26361 |
Author(s) : Boeszoermenyi A , Nagy HM , Arthanari H , Pillip CJ , Lindermuth H , Luna RE , Wagner G , Zechner R , Zangger K , Oberer M |
Ref : Journal of Biological Chemistry , 290 :26361 , 2015 |
Abstract : |
PubMedSearch : Boeszoermenyi_2015_J.Biol.Chem_290_26361 |
PubMedID: 26350461 |
Gene_locus related to this paper: human-ABHD5 |
Title : Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling - Hofer_2015_J.Biol.Chem_290_18438 |
Author(s) : Hofer P , Boeszoermenyi A , Jaeger D , Feiler U , Arthanari H , Mayer N , Zehender F , Rechberger G , Oberer M , Zimmermann R , Lass A , Haemmerle G , Breinbauer R , Zechner R , Preiss-Landl K |
Ref : Journal of Biological Chemistry , 290 :18438 , 2015 |
Abstract : |
PubMedSearch : Hofer_2015_J.Biol.Chem_290_18438 |
PubMedID: 25953897 |
Gene_locus related to this paper: human-ABHD5 |
Title : CGI-58\/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization - Sahu-Osen_2015_J.Lipid.Res_56_109 |
Author(s) : Sahu-Osen A , Montero-Moran G , Schittmayer M , Fritz K , Dinh A , Chang YF , McMahon D , Boeszoermenyi A , Cornaciu I , Russell D , Oberer M , Carman GM , Birner-Gruenberger R , Brasaemle DL |
Ref : J Lipid Res , 56 :109 , 2015 |
Abstract : |
PubMedSearch : Sahu-Osen_2015_J.Lipid.Res_56_109 |
PubMedID: 25421061 |
Gene_locus related to this paper: human-ABHD5 |
Title : Purification, crystallization and preliminary X-ray diffraction analysis of a soluble variant of the monoglyceride lipase Yju3p from the yeast Saccharomyces cerevisiae - Rengachari_2015_Acta.Crystallogr.F.Struct.Biol.Commun_71_243 |
Author(s) : Rengachari S , Aschauer P , Sturm C , Oberer M |
Ref : Acta Crystallographica F Struct Biol Commun , 71 :243 , 2015 |
Abstract : |
PubMedSearch : Rengachari_2015_Acta.Crystallogr.F.Struct.Biol.Commun_71_243 |
PubMedID: 25664804 |
Gene_locus related to this paper: yeast-mgll |
Title : Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A - Nagy_2014_Biochim.Biophys.Acta_1841_588 |
Author(s) : Nagy HM , Paar M , Heier C , Moustafa T , Hofer P , Haemmerle G , Lass A , Zechner R , Oberer M , Zimmermann R |
Ref : Biochimica & Biophysica Acta , 1841 :588 , 2014 |
Abstract : |
PubMedSearch : Nagy_2014_Biochim.Biophys.Acta_1841_588 |
PubMedID: 24440819 |
Title : The evolutionarily conserved protein CG9186 is associated with lipid droplets, required for their positioning and for fat storage - Thiel_2013_J.Cell.Sci_126_2198 |
Author(s) : Thiel K , Heier C , Haberl V , Thul PJ , Oberer M , Lass A , Jackle H , Beller M |
Ref : Journal of Cell Science , 126 :2198 , 2013 |
Abstract : |
PubMedSearch : Thiel_2013_J.Cell.Sci_126_2198 |
PubMedID: 23525007 |
Gene_locus related to this paper: drome-CG9186 |
Title : Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase - Rengachari_2013_J.Biol.Chem_288_31093 |
Author(s) : Rengachari S , Aschauer P , Schittmayer M , Mayer N , Gruber K , Breinbauer R , Birner-Gruenberger R , Dreveny I , Oberer M |
Ref : Journal of Biological Chemistry , 288 :31093 , 2013 |
Abstract : |
PubMedSearch : Rengachari_2013_J.Biol.Chem_288_31093 |
PubMedID: 24014019 |
Gene_locus related to this paper: bac25-mglp |
Title : Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase - Kumari_2012_Cell.Metab_15_691 |
Author(s) : Kumari M , Schoiswohl G , Chitraju C , Paar M , Cornaciu I , Rangrez AY , Wongsiriroj N , Nagy HM , Ivanova PT , Scott SA , Knittelfelder O , Rechberger GN , Birner-Gruenberger R , Eder S , Brown HA , Haemmerle G , Oberer M , Lass A , Kershaw EE , Zimmermann R , Zechner R |
Ref : Cell Metab , 15 :691 , 2012 |
Abstract : |
PubMedSearch : Kumari_2012_Cell.Metab_15_691 |
PubMedID: 22560221 |
Title : The structure of monoacylglycerol lipase from Bacillus sp. H257 reveals unexpected conservation of the cap architecture between bacterial and human enzymes - Rengachari_2012_Biochim.Biophys.Acta_1821_1012 |
Author(s) : Rengachari S , Bezerra GA , Riegler-Berket L , Gruber CC , Sturm C , Taschler U , Boeszoermenyi A , Dreveny I , Zimmermann R , Gruber K , Oberer M |
Ref : Biochimica & Biophysica Acta , 1821 :1012 , 2012 |
Abstract : |
PubMedSearch : Rengachari_2012_Biochim.Biophys.Acta_1821_1012 |
PubMedID: 22561231 |
Gene_locus related to this paper: bac25-mglp |
Title : Lipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores - Lass_2011_Prog.Lipid.Res_50_14 |
Author(s) : Lass A , Zimmermann R , Oberer M , Zechner R |
Ref : Prog Lipid Res , 50 :14 , 2011 |
Abstract : |
PubMedSearch : Lass_2011_Prog.Lipid.Res_50_14 |
PubMedID: 21087632 |
Title : Recent insights into the structure and function of comparative gene identification-58 - Oberer_2011_Curr.Opin.Lipidol_22_149 |
Author(s) : Oberer M , Boeszoermenyi A , Nagy HM , Zechner R |
Ref : Curr Opin Lipidol , 22 :149 , 2011 |
Abstract : |
PubMedSearch : Oberer_2011_Curr.Opin.Lipidol_22_149 |
PubMedID: 21494142 |
Gene_locus related to this paper: human-ABHD5 |
Title : The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively - Cornaciu_2011_PLoS.One_6_e26349 |
Author(s) : Cornaciu I , Boeszoermenyi A , Lindermuth H , Nagy HM , Cerk IK , Ebner C , Salzburger B , Gruber A , Schweiger M , Zechner R , Lass A , Zimmermann R , Oberer M |
Ref : PLoS ONE , 6 :e26349 , 2011 |
Abstract : |
PubMedSearch : Cornaciu_2011_PLoS.One_6_e26349 |
PubMedID: 22039468 |
Gene_locus related to this paper: human-ABHD5 |
Title : Identification of Yju3p as functional orthologue of mammalian monoglyceride lipase in the yeast Saccharomycescerevisiae - Heier_2010_Biochim.Biophys.Acta_1801_1063 |
Author(s) : Heier C , Taschler U , Rengachari S , Oberer M , Wolinski H , Natter K , Kohlwein SD , Leber R , Zimmermann R |
Ref : Biochimica & Biophysica Acta , 1801 :1063 , 2010 |
Abstract : |
PubMedSearch : Heier_2010_Biochim.Biophys.Acta_1801_1063 |
PubMedID: 20554061 |
Gene_locus related to this paper: human-MGLL , mouse-MGLL , yeast-mgll |
Title : The N-terminal region of comparative gene identification-58 (CGI-58) is important for lipid droplet binding and activation of adipose triglyceride lipase - Gruber_2010_J.Biol.Chem_285_12289 |
Author(s) : Gruber A , Cornaciu I , Lass A , Schweiger M , Poeschl M , Eder C , Kumari M , Schoiswohl G , Wolinski H , Kohlwein SD , Zechner R , Zimmermann R , Oberer M |
Ref : Journal of Biological Chemistry , 285 :12289 , 2010 |
Abstract : |
PubMedSearch : Gruber_2010_J.Biol.Chem_285_12289 |
PubMedID: 20164531 |
Title : The C-terminal region of human adipose triglyceride lipase affects enzyme activity and lipid droplet binding - Schweiger_2008_J.Biol.Chem_283_17211 |
Author(s) : Schweiger M , Schoiswohl G , Lass A , Radner FP , Haemmerle G , Malli R , Graier W , Cornaciu I , Oberer M , Salvayre R , Fischer J , Zechner R , Zimmermann R |
Ref : Journal of Biological Chemistry , 283 :17211 , 2008 |
Abstract : |
PubMedSearch : Schweiger_2008_J.Biol.Chem_283_17211 |
PubMedID: 18445597 |