| Title : Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes - Grabner_2022_J.Am.Chem.Soc__ |
| Author(s) : Grabner GF , Guttenberger N , Mayer N , Migglautsch-Sulzer AK , Lembacher-Fadum C , Fawzy N , Bulfon D , Hofer P , Zullig T , Hartig L , Kulminskaya N , Chalhoub G , Schratter M , Radner FPW , Preiss-Landl K , Masser S , Lass A , Zechner R , Gruber K , Oberer M , Breinbauer R , Zimmermann R |
| Ref : Journal of the American Chemical Society , : , 2022 |
| Abstract : |
| PubMedSearch : Grabner_2022_J.Am.Chem.Soc__ |
| PubMedID: 35362954 |
| Title : Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL) - Mayer_2020_Bioorg.Med.Chem_28_115610 |
| Author(s) : Mayer N , Schweiger M , Fuchs E , Migglautsch AK , Doler C , Grabner GF , Romauch M , Melcher MC , Zechner R , Zimmermann R , Breinbauer R |
| Ref : Bioorganic & Medicinal Chemistry , 28 :115610 , 2020 |
| Abstract : |
| PubMedSearch : Mayer_2020_Bioorg.Med.Chem_28_115610 |
| PubMedID: 32690265 |
| Title : Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice - Schweiger_2017_Nat.Commun_8_14859 |
| Author(s) : Schweiger M , Romauch M , Schreiber R , Grabner GF , Hutter S , Kotzbeck P , Benedikt P , Eichmann TO , Yamada S , Knittelfelder O , Diwoky C , Doler C , Mayer N , De Cecco W , Breinbauer R , Zimmermann R , Zechner R |
| Ref : Nat Commun , 8 :14859 , 2017 |
| Abstract : |
| PubMedSearch : Schweiger_2017_Nat.Commun_8_14859 |
| PubMedID: 28327588 |
| Title : Crystal structure of the Saccharomyces cerevisiae monoglyceride lipase Yju3p - Aschauer_2016_Biochim.Biophys.Acta_1861_462 |
| Author(s) : Aschauer P , Rengachari S , Lichtenegger J , Schittmayer M , Das KM , Mayer N , Breinbauer R , Birner-Gruenberger R , Gruber CC , Zimmermann R , Gruber K , Oberer M |
| Ref : Biochimica & Biophysica Acta , 1861 :462 , 2016 |
| Abstract : |
| PubMedSearch : Aschauer_2016_Biochim.Biophys.Acta_1861_462 |
| PubMedID: 26869448 |
| Gene_locus related to this paper: yeast-mgll |
| Title : Structure-activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL) - Mayer_2015_Bioorg.Med.Chem_23_2904 |
| Author(s) : Mayer N , Schweiger M , Melcher MC , Fledelius C , Zechner R , Zimmermann R , Breinbauer R |
| Ref : Bioorganic & Medicinal Chemistry , 23 :2904 , 2015 |
| Abstract : |
| PubMedSearch : Mayer_2015_Bioorg.Med.Chem_23_2904 |
| PubMedID: 25778769 |
| Title : Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling - Hofer_2015_J.Biol.Chem_290_18438 |
| Author(s) : Hofer P , Boeszoermenyi A , Jaeger D , Feiler U , Arthanari H , Mayer N , Zehender F , Rechberger G , Oberer M , Zimmermann R , Lass A , Haemmerle G , Breinbauer R , Zechner R , Preiss-Landl K |
| Ref : Journal of Biological Chemistry , 290 :18438 , 2015 |
| Abstract : |
| PubMedSearch : Hofer_2015_J.Biol.Chem_290_18438 |
| PubMedID: 25953897 |
| Gene_locus related to this paper: human-ABHD5 |
| Title : Development of small-molecule inhibitors targeting adipose triglyceride lipase - Mayer_2013_Nat.Chem.Biol_9_785 |
| Author(s) : Mayer N , Schweiger M , Romauch M , Grabner GF , Eichmann TO , Fuchs E , Ivkovic J , Heier C , Mrak I , Lass A , Hofler G , Fledelius C , Zechner R , Zimmermann R , Breinbauer R |
| Ref : Nat Chemical Biology , 9 :785 , 2013 |
| Abstract : |
| PubMedSearch : Mayer_2013_Nat.Chem.Biol_9_785 |
| PubMedID: 24096302 |
| Title : Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase - Rengachari_2013_J.Biol.Chem_288_31093 |
| Author(s) : Rengachari S , Aschauer P , Schittmayer M , Mayer N , Gruber K , Breinbauer R , Birner-Gruenberger R , Dreveny I , Oberer M |
| Ref : Journal of Biological Chemistry , 288 :31093 , 2013 |
| Abstract : |
| PubMedSearch : Rengachari_2013_J.Biol.Chem_288_31093 |
| PubMedID: 24014019 |
| Gene_locus related to this paper: bac25-mglp |
| Title : Pharmacological profile of selective muscarinic receptor antagonists on guinea-pig ileal smooth muscle - Doods_1994_Eur.J.Pharmacol_253_275 |
| Author(s) : Doods HN , Entzeroth M , Ziegler H , Mayer N , Holzer P |
| Ref : European Journal of Pharmacology , 253 :275 , 1994 |
| Abstract : |
| PubMedSearch : Doods_1994_Eur.J.Pharmacol_253_275 |
| PubMedID: 8200421 |
| Title : The binding of [3H]AF-DX 384 to rat ileal smooth muscle muscarinic receptors - Entzeroth_1991_J.Recept.Res_11_141 |
| Author(s) : Entzeroth M , Mayer N |
| Ref : J Recept Res , 11 :141 , 1991 |
| Abstract : |
| PubMedSearch : Entzeroth_1991_J.Recept.Res_11_141 |
| PubMedID: 1886077 |
| Title : Cardioselectivity of AQ-RA 741, a novel tricyclic antimuscarinic drug - Doods_1991_Eur.J.Pharmacol_192_147 |
| Author(s) : Doods HN , Entzeroth M , Mayer N |
| Ref : European Journal of Pharmacology , 192 :147 , 1991 |
| Abstract : |
| PubMedSearch : Doods_1991_Eur.J.Pharmacol_192_147 |
| PubMedID: 2040358 |
| Title : Labeling of rat heart muscarinic receptors using the new M2 selective antagonist [3H]AF-DX 384 - |
| Author(s) : Entzeroth M , Mayer N |
| Ref : Biochemical Pharmacology , 40 :1674 , 1990 |
| PubMedID: 2222523 |
| Title : Characterization of porcine coronary muscarinic receptors - Entzeroth_1990_Naunyn.Schmiedebergs.Arch.Pharmacol_341_432 |
| Author(s) : Entzeroth M , Doods HN , Mayer N |
| Ref : Naunyn Schmiedebergs Arch Pharmacol , 341 :432 , 1990 |
| Abstract : |
| PubMedSearch : Entzeroth_1990_Naunyn.Schmiedebergs.Arch.Pharmacol_341_432 |
| PubMedID: 2366878 |
| Title : UH-AH 37, an ileal-selective muscarinic antagonist that does not discriminate between M2 and M3 binding sites - Doods_1989_Eur.J.Pharmacol_161_215 |
| Author(s) : Doods HN , Mayer N |
| Ref : European Journal of Pharmacology , 161 :215 , 1989 |
| Abstract : |
| PubMedSearch : Doods_1989_Eur.J.Pharmacol_161_215 |
| PubMedID: 2721554 |
| Title : Structure-activity relationships and pharmacological profile of selective tricyclic antimuscarinics - Eberlein_1989_Trends.Pharmacol.Sci_Suppl_50 |
| Author(s) : Eberlein WG , Engel W , Mihm G , Rudolf K , Wetzel B , Entzeroth M , Mayer N , Doods HN |
| Ref : Trends in Pharmacological Sciences , Suppl :50 , 1989 |
| Abstract : |
| PubMedSearch : Eberlein_1989_Trends.Pharmacol.Sci_Suppl_50 |
| PubMedID: 2694523 |
| Title : Poster: Affinity of muscarinic .ar:Jtagonists for porcine coronary muscannlc receptors - |
| Author(s) : Entzeroth M , Doods HN , Mayer N |
| Ref : Trends in Pharmacological Sciences , Suppl :106 , 1989 |
| PubMedID: |
| Title : Fentanyl inhibits the canine carotid chemoreceptor reflex - Mayer_1989_Anesth.Analg_69_756 |
| Author(s) : Mayer N , Zimpfer M , Raberger G , Beck A |
| Ref : Anesthesia & Analgesia , 69 :756 , 1989 |
| Abstract : |
| PubMedSearch : Mayer_1989_Anesth.Analg_69_756 |
| PubMedID: 2589656 |
| Title : Poster: AQ-RA 741- a New cardioselective (M2) muscarinic antogonist - |
| Author(s) : Eberlein W , Engel W , Mihm G , Mayer N , Doods HN |
| Ref : Trends in Pharmacological Sciences , Suppl :113 , 1989 |
| PubMedID: |
| Title : Tricyclic compounds as selective antimuscarinics. 1. Structural requirements for selectivity toward the muscarinic acetylcholine receptor in a series of pirenzepine and imipramine analogues - Eberlein_1987_J.Med.Chem_30_1378 |
| Author(s) : Eberlein WG , Trummlitz G , Engel WW , Schmidt G , Pelzer H , Mayer N |
| Ref : Journal of Medicinal Chemistry , 30 :1378 , 1987 |
| Abstract : |
| PubMedSearch : Eberlein_1987_J.Med.Chem_30_1378 |
| PubMedID: 3039133 |
| Title : Poster: Temperature dependence of specific pirenzepine binding to M1 and M2 receptors - |
| Author(s) : Mayer N |
| Ref : Trends in Pharmacological Sciences , Suppl :78 , 1986 |
| PubMedID: |