C16-stearoyl-MAG-like-phosphonate
mimics the Monoacylglycerol MAG of identical size (here the 1-stearylglycerol Monostearin (C18:0)). The adduct on the active serine lacks the leaving group 4-nitrophenol
General
Type : Organophosphate, Analogue of substrate, Lipase inhibitor, pNP, Azido
Chemical_Nomenclature : 3-[hexadecoxy(hydroxy)phosphoryl]propylimino-iminoazanium
Canonical SMILES : CCCCCCCCCCCCCCCCOP(=O)(CCCN=[N+]=N)O
InChI : InChI=1S\/C19H40N3O3P\/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18-25-26(23,24)19-16-17-21-22-20\/h20H,2-19H2,1H3\/p+1
InChIKey : MYGDUEKFBFOIEJ-UHFFFAOYSA-O
Other name(s) : Hexadecyl Hydrogen (R)-(3-Azidopropyl)phosphonate || 1R1
MW : 390.52 || 510,61
Formula : C19H41N3O3P+ || C25H43N4O5P
CAS_number :
PubChem : 71710909
UniChem : MYGDUEKFBFOIEJ-UHFFFAOYSA-O
Target
Families : C16-stearoyl-MAG-like-phosphonate ligand of proteins in family
CarbLipBact_2
Structure :
4KE9
Protein :
bac25-mglp
References (1)
| Title : Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase - Rengachari_2013_J.Biol.Chem_288_31093 |
| Author(s) : Rengachari S , Aschauer P , Schittmayer M , Mayer N , Gruber K , Breinbauer R , Birner-Gruenberger R , Dreveny I , Oberer M |
| Ref : Journal of Biological Chemistry , 288 :31093 , 2013 |
| Abstract : |
| PubMedSearch : Rengachari_2013_J.Biol.Chem_288_31093 |
| PubMedID: 24014019 |
| Gene_locus related to this paper: bac25-mglp |