Cannabidiol-amide-CB7
CB7 BChE inhibitor IC50 = 0.31 +/- 0.09 M,showed good antioxidant behavior, anti-tyrosinase activity IC50=0.037+/-0.003microM, AChE IC50=19.73+/-0.79microM
General
Type : Cannabinoid-Receptor-ligand, Multitarget, Carbamate
Chemical_Nomenclature :
Canonical SMILES : C1C[C@@H]([C@@H](C=C1C)C2=C(C=C(C=C2OC(=O)C(NC(=O)OC(C)(C)C)CC(=O)OCC3=CC=CC=C3)CCCCC)O)C(=C)C
InChI : InChI=1S\/C37H49NO7\/c1-8-9-11-16-27-20-31(39)34(29-19-25(4)17-18-28(29)24(2)3)32(21-27)44-35(41)30(38-36(42)45-37(5,6)7)22-33(40)43-23-26-14-12-10-13-15-26\/h10,12-15,19-21,28-30,39H,2,8-9,11,16-18,22-23H2,1,3-7H3,(H,38,42)\/t28-,29-,30?\/m1\/s1
InChIKey : XOYPKRXPFFACQP-HPSQJEMFSA-N
Other name(s) :
Target
Families : Cannabidiol-amide-CB7 ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : Synthesis and evaluation of a highly selective cannabidiol amide cholinesterase inhibitor - Zhang_2024_Results.Chem_7_101492 |
| Author(s) : Zhang R , Zhao M , Wang D , Zhao Y , Li J , Zhang S , Zhang W , Shi Z |
| Ref : Results in Chemistry , 7 :101492 , 2024 |
| Abstract : |
| PubMedSearch : Zhang_2024_Results.Chem_7_101492 |
| PubMedID: |