CyC-7beta
General
Type : Organophosphate, Cyclic OP, Lipase inhibitor
Chemical_Nomenclature : methyl (2R,5R)-5-decyl-2-methoxy-7-methyl-2-oxo-4,5-dihydro-3H-1,2$l^{5}-oxaphosphepine-6-carboxylate || methoxy-[(E,3R)-3-[(2R)-1-methoxy-1,3-dioxobutan-2-yl]tridec-11-enyl]phosphinic acid
Canonical SMILES : C\/C=C\/CCCCCCC[C@H](CCP(=O)(O)OC)[C@H](C(=O)C)C(=O)OC
InChI : InChI=1S\/C19H35O5P\/c1-5-6-7-8-9-10-11-12-13-17-14-15-25(21,23-4)24-16(2)18(17)19(20)22-3\/h17H,5-15H2,1-4H3\/t17-,25-\/m1\/s1 || InChI=1S\/C19H35O6P\/c1-5-6-7-8-9-10-11-12-13-17(14-15-26(22,23)25-4)18(16(2)20)19(21)24-3\/h5-6,17-18H,7-15H2,1-4H3,(H,22,23)\/b6-5+\/t17-,18+\/m1\/s1
InChIKey : NHTZROPHLCBBHP-CRICUBBOSA-N || KFPPYXMTKZSOKI-VGRIIWOTSA-N
Other name(s) : CyC7b || CyC-7b || IY8
MW : 374.45
Formula : C19H35O5P
CAS_number :
UniChem : NHTZROPHLCBBHP-CRICUBBOSA-N, KFPPYXMTKZSOKI-VGRIIWOTSA-N
Target
Families : CyC-7beta ligand of proteins in family
A85-Mycolyl-transferase
Structure :
7ZM1
Protein :
myctu-a85c
References (1)
| Title : Cyclipostins and cyclophostin analogs inhibit the antigen 85C from Mycobacterium tuberculosis both in vitro and in vivo - Viljoen_2018_J.Biol.Chem_293_2755 |
| Author(s) : Viljoen A , Richard M , Nguyen PC , Fourquet P , Camoin L , Paudal RR , Gnawali GR , Spilling CD , Cavalier JF , Canaan S , Blaise M , Kremer L |
| Ref : Journal of Biological Chemistry , 293 :2755 , 2018 |
| Abstract : |
| PubMedSearch : Viljoen_2018_J.Biol.Chem_293_2755 |
| PubMedID: 29301937 |
| Gene_locus related to this paper: myctu-a85c |