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Cyclic OP

General

Cyclic Organophosphates. First natural OPs were isolated from the mycelium of Streptomyces species. Cyclophostin-like and Cyclipostin-like are promising compounds in the fight against tuberculosis. This type also contains Phenyl-saligenin-phosphate a potent delayed neurotoxin
Inhibitor Main targeted enzyme families Type Structure
S9B Organophosphate Cyclic OP NTE inhibitor OPIDN-OP Not AlphaBeta Hydrolase target Sulfur Compound Biotin derivative
Salithion BCHE ACHE Organophosphate Cyclic OP Sulfur Compound
Salioxon BCHE Organophosphate Cyclic OP
Phenyl-BDPO Organophosphate NTE inhibitor Cyclic OP Not AlphaBeta Hydrolase target OPIDN-OP
OBDPO Organophosphate NTE inhibitor Cyclic OP Not AlphaBeta Hydrolase target OPIDN-OP
CBDP ACHE BCHE Carb_B_Chordata Organophosphate Cyclic OP NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP
Cyclophostin ACHE Organophosphate Natural Cyclic OP
CyC-31 Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor
CyC-31yne Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor Alkyne
CyC-32 Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor
CyC-32yne Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor Alkyne
CyC-31-open Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor Cyclic OP open
Cyclipostin Hormone-sensitive_lipase_like Organophosphate Cyclic OP
Cyclophostin-enolphosphonate Cutinase Monoglyceridelipase_lysophospholip Organophosphate Cyclic OP Lipase inhibitor
Sal-A-alkyne Plasmodium_subtelomeric_PST-A ABHD13-BEM46 Duf_676 PGAP1 ABHD17-depalmitoylase Organophosphate Cyclic OP Lipase inhibitor ABPP-Probe Alkyne
Salinipostin-A Plasmodium_subtelomeric_PST-A ABHD13-BEM46 Duf_676 PGAP1 ABHD17-depalmitoylase Organophosphate Cyclic OP Lipase inhibitor Natural
Cyclipostin-P Hormone-sensitive_lipase_like Monoglyceridelipase_lysophospholip Cutinase Organophosphate Cyclic OP Lipase inhibitor Natural
CyC-17 A85-Mycolyl-transferase Hormone-sensitive_lipase_like Cutinase Carbon-carbon_bond_hydrolase Thioesterase Organophosphate Cyclic OP Lipase inhibitor
CyC-17-open A85-Mycolyl-transferase Organophosphate Cyclic OP open Lipase inhibitor
CyC-7beta A85-Mycolyl-transferase Organophosphate Cyclic OP Lipase inhibitor
CyC-7beta-open A85-Mycolyl-transferase Organophosphate Cyclic OP open Lipase inhibitor
CyC-8beta A85-Mycolyl-transferase Organophosphate Cyclic OP Lipase inhibitor
CyC-8beta-open A85-Mycolyl-transferase Organophosphate Cyclic OP open Lipase inhibitor
CGA-134-736 ACHE Organophosphate Cyclic OP Natural
CGA-134-735 ACHE Organophosphate Cyclic OP Natural
Phenyl-saligenin-phosphate~PSP BCHE Organophosphate Cyclic OP NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP
S9B Organophosphate Cyclic OP NTE inhibitor OPIDN-OP Not AlphaBeta Hydrolase target Sulfur compound Biotin derivative
Salithion BCHE ACHE Organophosphate Cyclic OP Sulfur compound
Salioxon BCHE Organophosphate Cyclic OP
Phenyl-BDPO Organophosphate NTE inhibitor Cyclic OP Not AlphaBeta Hydrolase target OPIDN-OP
OBDPO Organophosphate NTE inhibitor Cyclic OP Not AlphaBeta Hydrolase target OPIDN-OP
CBDP ACHE BCHE Carb_B_Chordata Organophosphate Cyclic OP NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP
Cyclophostin ACHE Organophosphate Natural Cyclic OP
CyC-31 Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor
CyC-31yne Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor Alkyne
CyC-32 Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor
CyC-32yne Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor Alkyne
CyC-31-open Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor Cyclic OP open
Cyclipostin Hormone-sensitive_lipase_like Organophosphate Cyclic OP
Cyclophostin-enolphosphonate Cutinase Monoglyceridelipase_lysophospholip Organophosphate Cyclic OP Lipase inhibitor
Sal-A-alkyne Plasmodium_subtelomeric_PST-A ABHD13-BEM46 Duf_676 PGAP1 ABHD17-depalmitoylase Organophosphate Cyclic OP Lipase inhibitor ABPP-Probe Alkyne
Salinipostin-A Plasmodium_subtelomeric_PST-A ABHD13-BEM46 Duf_676 PGAP1 ABHD17-depalmitoylase Organophosphate Cyclic OP Lipase inhibitor Natural
Cyclipostin-P Hormone-sensitive_lipase_like Monoglyceridelipase_lysophospholip Cutinase Organophosphate Cyclic OP Lipase inhibitor Natural
CyC-17 A85-Mycolyl-transferase Hormone-sensitive_lipase_like Cutinase Carbon-carbon_bond_hydrolase Thioesterase Organophosphate Cyclic OP Lipase inhibitor
CyC-17-open A85-Mycolyl-transferase Organophosphate Cyclic OP open Lipase inhibitor
CyC-7beta A85-Mycolyl-transferase Organophosphate Cyclic OP Lipase inhibitor
CyC-7beta-open A85-Mycolyl-transferase Organophosphate Cyclic OP open Lipase inhibitor
CyC-8beta A85-Mycolyl-transferase Organophosphate Cyclic OP Lipase inhibitor
CyC-8beta-open A85-Mycolyl-transferase Organophosphate Cyclic OP open Lipase inhibitor
CGA-134-736 ACHE Organophosphate Cyclic OP Natural
CGA-134-735 ACHE Organophosphate Cyclic OP Natural
Phenyl-saligenin-phosphate~PSP BCHE Organophosphate Cyclic OP NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP
S9B Organophosphate Cyclic OP NTE inhibitor OPIDN-OP Not AlphaBeta Hydrolase target Sulfur compound Biotin derivative
Salithion BCHE ACHE Organophosphate Cyclic OP Sulfur compound
Salioxon BCHE Organophosphate Cyclic OP
Phenyl-BDPO Organophosphate NTE inhibitor Cyclic OP Not AlphaBeta Hydrolase target OPIDN-OP
OBDPO Organophosphate NTE inhibitor Cyclic OP Not AlphaBeta Hydrolase target OPIDN-OP
CBDP ACHE BCHE Carb_B_Chordata Organophosphate Cyclic OP NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP
Cyclophostin ACHE Organophosphate Natural Cyclic OP
CyC-31 Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor
CyC-31yne Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor Alkyne
CyC-32 Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor
CyC-32yne Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor Alkyne
CyC-31-open Carbon-carbon_bond_hydrolase Organophosphate Cyclic OP Lipase inhibitor Cyclic OP open
Cyclipostin Hormone-sensitive_lipase_like Organophosphate Cyclic OP
Cyclophostin-enolphosphonate Cutinase Monoglyceridelipase_lysophospholip Organophosphate Cyclic OP Lipase inhibitor
Sal-A-alkyne Plasmodium_subtelomeric_PST-A ABHD13-BEM46 Duf_676 PGAP1 ABHD17-depalmitoylase Organophosphate Cyclic OP Lipase inhibitor ABPP-Probe Alkyne
Salinipostin-A Plasmodium_subtelomeric_PST-A ABHD13-BEM46 Duf_676 PGAP1 ABHD17-depalmitoylase Organophosphate Cyclic OP Lipase inhibitor Natural
Cyclipostin-P Hormone-sensitive_lipase_like Monoglyceridelipase_lysophospholip Cutinase Organophosphate Cyclic OP Lipase inhibitor Natural
CyC-17 A85-Mycolyl-transferase Hormone-sensitive_lipase_like Cutinase Carbon-carbon_bond_hydrolase Thioesterase Organophosphate Cyclic OP Lipase inhibitor
CyC-17-open A85-Mycolyl-transferase Organophosphate Cyclic OP open Lipase inhibitor
CyC-7beta A85-Mycolyl-transferase Organophosphate Cyclic OP Lipase inhibitor
CyC-7beta-open A85-Mycolyl-transferase Organophosphate Cyclic OP open Lipase inhibitor
CyC-8beta A85-Mycolyl-transferase Organophosphate Cyclic OP Lipase inhibitor
CyC-8beta-open A85-Mycolyl-transferase Organophosphate Cyclic OP open Lipase inhibitor
CGA-134-736 ACHE Organophosphate Cyclic OP Natural
CGA-134-735 ACHE Organophosphate Cyclic OP Natural
Phenyl-saligenin-phosphate~PSP BCHE Organophosphate Cyclic OP NTE inhibitor Not AlphaBeta Hydrolase target OPIDN-OP