DECF
General
Type : Carbamate
Chemical_Nomenclature : [5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-2,3-dihydrochromen-7-yl] N,N-diethylcarbamate
Canonical SMILES : CCN(CC)C(=O)OC1=CC(=C2C(=O)CC(OC2=C1)C3=CC=C(C=C3)O)O
InChI : InChI=1S\/C20H21NO6\/c1-3-21(4-2)20(25)26-14-9-15(23)19-16(24)11-17(27-18(19)10-14)12-5-7-13(22)8-6-12\/h5-10,17,22-23H,3-4,11H2,1-2H3
InChIKey : NVEYRABGVSOBBY-UHFFFAOYSA-N
Other name(s) : CHEMBL5178833, BDBM50599808
MW : 71.4
Formula : C20H21NO6
CAS_number :
PubChem : 168275491
UniChem : NVEYRABGVSOBBY-UHFFFAOYSA-N
Target
Families : DECF ligand of proteins in family
Carboxylesterase
Carb_B_Chordata
Protein :
human-CES2
References (2)
| Title : Rationally Engineered hCES2A Near-Infrared Fluorogenic Substrate for Functional Imaging and High-Throughput Inhibitor Screening - Fan_2023_Anal.Chem_95_15665 |
| Author(s) : Fan Y , Zhang T , Song Y , Sang Z , Zeng H , Liu P , Wang P , Ge G |
| Ref : Analytical Chemistry , 95 :15665-15672 , 2023 |
| PubMedID: 37782032 |
| Gene_locus related to this paper: human-CES2 |
| Title : Development of naringenin-O-carbamate derivatives as multi-target-directed liagnds for the treatment of Alzheimer's disease - Mi_2022_Bioorg.Med.Chem.Lett_60_128574 |
| Author(s) : Mi J , He Y , Yang J , Zhou Y , Zhu G , Wu A , Liu W , Sang Z |
| Ref : Bioorganic & Medicinal Chemistry Lett , 60 :128574 , 2022 |
| PubMedID: 35065231 |