Family: Carboxylesterase

Block: C

Parent Family: No family


"Higher eukaryotes have many distinct esterases. The different types include those that act on carboxylic esters (EC 3.1.1). Carboxyl-esterases have been classified into three categories (A, B and C) on the basis of differential patterns of inhibition by organophosphates. Here are B type. WARNING There is no Plant carboxylesterases in this family except an EST from sorgho (sorbi-cxest) which could be a contaminant. Plant carboxylesterases do not possess SEDCLYLN and are included in a specific family: Plant_carboxylesterase. This family corresponds to the Carbohydrate Esterase family CE10 in CAZy - Carbohydrate-Active enZYmes database (CE_10). For bacterial enzymes this family correspond to family VII of the classification of Arpigny and Jaeger (1999)"


Interpro : IPR002018 Carboxylesterase, type B

PIRSF : PIRSF005676 COesterase

Pdoc : PDOC00112

Pfam : PF00135 COesterase

Prints : No Print

EC Number :


Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour
Alignment with MAFFT No colour
Dendrogram The dnd file

References (3)

Title : Carboxyl ester lipase: structure-function relationship and physiological role in lipoprotein metabolism and atherosclerosis - Hui_2002_J.Lipid.Res_43_2017
Author(s) : Hui DY , Howles PN
Ref : J Lipid Res , 43 :2017 , 2002
Abstract : Hui_2002_J.Lipid.Res_43_2017
ESTHER : Hui_2002_J.Lipid.Res_43_2017
PubMedSearch : Hui_2002_J.Lipid.Res_43_2017
PubMedID: 12454261

Title : Carboxyl\/cholinesterases: a case study of the evolution of a successful multigene family - Oakeshott_1999_Bioessays_21_1031
Author(s) : Oakeshott JG , Claudianos C , Russell RJ , Robin GC
Ref : Bioessays , 21 :1031 , 1999
Abstract : Oakeshott_1999_Bioessays_21_1031
ESTHER : Oakeshott_1999_Bioessays_21_1031
PubMedSearch : Oakeshott_1999_Bioessays_21_1031
PubMedID: 10580988

Title : The mammalian carboxylesterases: from molecules to functions - Satoh_1998_Annu.Rev.Pharmacol.Toxicol_38_257
Author(s) : Satoh T , Hosokawa M
Ref : Annual Review of Pharmacology & Toxicology , 38 :257 , 1998
Abstract : Satoh_1998_Annu.Rev.Pharmacol.Toxicol_38_257
ESTHER : Satoh_1998_Annu.Rev.Pharmacol.Toxicol_38_257
PubMedSearch : Satoh_1998_Annu.Rev.Pharmacol.Toxicol_38_257
PubMedID: 9597156

No structure scheme yet for this family

No Genes Proteins

No fragment of genes

No fragment of genes

Substrates in Carboxylesterase family (17)

Inhibitors in Carboxylesterase family (12)