JP-4-1-7
General
Type : Pyrrolidine, Pyrazole, Pyridine, Carboxamide
Chemical_Nomenclature : 4-chloro-1-(cyclohexylmethyl)-3-methyl-N-[3-oxo-3-(pyrrolidin-1-yl)propyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
Canonical SMILES : CC2=N[N](CC1CCCCC1)C3=C2C(=C(C=N3)C(=O)NCCC(=O)N4CCCC4)Cl
InChI : InChI=1S\/C22H30ClN5O2\/c1-15-19-20(23)17(22(30)24-10-9-18(29)27-11-5-6-12-27)13-25-21(19)28(26-15)14-16-7-3-2-4-8-16\/h13,16H,2-12,14H2,1H3,(H,24,30)
InChIKey : MOXROVYUYLMHQQ-UHFFFAOYSA-N
Other name(s) : A1CQP || A1CQU
Target
Families : JP-4-1-7 ligand of proteins in family
S9N_PPCE_Peptidase_S9
Structure :
9Q66
Protein :
human-PREP
References (1)
| Title : Structure-Guided Optimization of 4-Chloro-Pyrazolopyridine Analogs for Covalent PREP Inhibition - Thakur_2026_J.Med.Chem__ |
| Author(s) : Thakur K , Fucci I , Pandian J , Suazo KF , Monteiro DCF , Yoo E |
| Ref : Journal of Medicinal Chemistry , : , 2026 |
| Abstract : |
| PubMedSearch : Thakur_2026_J.Med.Chem__ |
| PubMedID: 41512187 |
| Gene_locus related to this paper: human-PREPL |