Piperidine-fused-benzimidazole-34
General
Type : Trifluoro, Piperidine, Benzimidazole
Chemical_Nomenclature :
Canonical SMILES : C1C(C(CN2C1=NC3=C2C=CN=C3)N)C4=CC(=C(C=C4F)F)F
InChI : InChI=1S\/C16H13F3N4\/c17-10-5-12(19)11(18)3-8(10)9-4-16-22-14-6-21-2-1-15(14)23(16)7-13(9)20\/h1-3,5-6,9,13H,4,7,20H2\/t9-,13+\/m1\/s1
InChIKey : SOSYXEPELJIJHZ-RNCFNFMXSA-N || SOSYXEPELJIJHZ-RNCFNFMXSA-O
Other name(s) : 361 || CHEMBL552068 || (7r,8r)-8-(2,4,5-Trifluorophenyl)-6,7,8,9-Tetrahydroimidazo[1,2-A:4,5-C']dipyridin-7-Amine || CHEMBL1194345 || BDBM50296490 || DB07021 || (11R,12R)-11-(2,4,5-trifluorophenyl)-1,5,8-triazatricyclo[7.4.0.0^{2,7}]trideca-2,4,6,8-tetraen-12-amine
MW : 318.30
Formula : C16H13F3N4
CAS_number :
UniChem : SOSYXEPELJIJHZ-RNCFNFMXSA-N, SOSYXEPELJIJHZ-RNCFNFMXSA-O
Target
Families : Piperidine-fused-benzimidazole-34 ligand of proteins in family
DPP4N_Peptidase_S9
Structure :
3HAC
Protein :
human-DPP4
References (1)
| Title : Aminopiperidine-fused imidazoles as dipeptidyl peptidase-IV inhibitors - Edmondson_2009_Bioorg.Med.Chem.Lett_19_4097 |
| Author(s) : Edmondson SD , Mastracchio A , Cox JM , Eiermann GJ , He H , Lyons KA , Patel RA , Patel SB , Petrov A , Scapin G , Wu JK , Xu S , Zhu B , Thornberry NA , Roy RS , Weber AE |
| Ref : Bioorganic & Medicinal Chemistry Lett , 19 :4097 , 2009 |
| Abstract : |
| PubMedSearch : Edmondson_2009_Bioorg.Med.Chem.Lett_19_4097 |
| PubMedID: 19539471 |
| Gene_locus related to this paper: human-DPP4 |