Benzimidazole

General

Bicyclic compound consists of the fusion of benzene and imidazole. Building block of anthelmintic drugs fungicides and other drugs

Inhibitor	Main targeted enzyme families	Type
Bromochlorophenyl-dihydropyrimido-benzimidazole-carboxylate-Cpd3e	ACHE	Carboxylate Pyrimidine Benzimidazole
CHEMBL83103	Epoxide_hydrolase	Fragment inhibitor of EPHX2 Pyridine Benzimidazole
Benzimidazole-alkanesulfonate-Cpd4q	ACHE	Benzimidazole Sulfur Compound
Chloro-benzimidazol-phenyl-ethyl-triazol-thio-dihydroxyphenyl-ethanone	ACHE	Benzimidazole Triazol Dihydroxyphenyl Sulfur Compound
IMS-48	ACHE	Benzimidazole
CHEMBL3290209	BCHE	Pyrrolidine Benzimidazole
DNP-BIM-PP	ACHE	Derivative of Donepezil Multitarget Benzimidazole Metal ion chelator
RIV-BIM-4d	ACHE	Monoamine-oxidase-inhibitor Multitarget Derivative of Rivastigmine Stigmine Benzimidazole
TAC-BIM-11d	ACHE	Derivative of Tacrine Acridine Benzimidazole Carboxamide Multitarget anti-Abeta-aggregation Organochlorine
CHEMBL4561138	Epoxide_hydrolase	Benzimidazole Sulfur Compound
Benzimidazole-Diethylcarbamoyl-isopentyl-dimethylcarbamate-15d	BCHE	Cannabinoid-Receptor-ligand Benzimidazole Carbamate Carboxamide Multitarget
Benzimidazole-Ethoxybenzyl-isopentyl-azetidine-carboxylate-21d	BCHE	Cannabinoid-Receptor-ligand Benzimidazole Carbamate Carboxamide Multitarget Azetidin
Benzimidazole-phenyl-azetidine-carboxylate-11d	BCHE	Cannabinoid-Receptor-ligand Benzimidazole Carbamate Carboxamide Multitarget Azetidin
Cpd20-Benzimidazol-Oxadiazol	BCHE	Benzimidazole Oxadiazol Cyanide Carboxamide
S16-1029	BCHE	Benzimidazole Oxadiazol Morpholine Carboxamide
Fragment-934	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Benzimidazole
Fragment-065	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Benzimidazole
Fragment-154	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Benzimidazole Cyanide
Fragment-173	Pectinacetylesterase-Notum	Fragment inhibitor of Notum Benzimidazole Cyanide
CHEMBL3233605-S0D-3WK7	Epoxide_hydrolase	Benzimidazole Pyrazole
S06-1011	BCHE	Quinoline Imidazole Oxadiazol Benzimidazole
8012-9656	BCHE	Quinoline Imidazole Oxadiazol Benzimidazole
RIV-BIMb-5d	BCHE	Derivative of Rivastigmine Stigmine Carbamate Carboxamide Benzimidazole
Piperidine-fused-benzimidazole-25	DPP4N_Peptidase_S9	Trifluoro Piperidine Sulfur Compound Imidazole Benzimidazole Sulfonyl
Piperidine-fused-benzimidazole-34	DPP4N_Peptidase_S9	Trifluoro Piperidine Benzimidazole
Benzimidazole-derivative-2	DPP4N_Peptidase_S9	Cyanide Imidazole Benzimidazole Organochlorine
CHEMBL1684295	Prolylcarboxypeptidase	Pyrrolidine Imidazole Pyridine Oxadiazol Piperidine Benzimidazole Organochlorine
UCI-80224067	Prolylcarboxypeptidase	Pyrrolidine Imidazole Benzimidazole Organochlorine
SZC	Epoxide_hydrolase	Sulfur Compound Sulfonamide Trifluoro Imidazole Benzimidazole
Benomyl	ACHE	Carbamate Fungicide Imidazole Benzimidazole
CHEMBL4456083	BCHE	Derivative of Tacrine Alkyl linked bis-ligand Acridine Benzimidazole Carboxamide