SZC
General
Type : Sulfur Compound, Sulfonamide, Trifluoro, Imidazole, Benzimidazole
Chemical_Nomenclature : N-cyclopentyl-2-[4-(trifluoromethyl)phenyl]-3H-benzimidazole-4-sulfonamide
Canonical SMILES : FC(F)(F)c1ccc(cc1)-c1nc2cccc(c2[nH]1)S(=O)(=O)NC1CCCC1
InChI : InChI=1S\/C19H18F3N3O2S\/c20-19(21,22)13-10-8-12(9-11-13)18-23-15-6-3-7-16(17(15)24-18)28(26,27)25-14-4-1-2-5-14\/h3,6-11,14,25H,1-2,4-5H2,(H,23,24)
InChIKey : BCAADIRANQOVRJ-UHFFFAOYSA-N
Other name(s) :
MW : 409.43
Formula : C19H18F3N3O2S
CAS_number :
PubChem : 118704920
UniChem : BCAADIRANQOVRJ-UHFFFAOYSA-N
Target
Families : SZC ligand of proteins in family
Epoxide_hydrolase
Structure :
5FP0
Protein :
human-EPHX2
References (1)
| Title : Fragment Screening of Soluble Epoxide Hydrolase for Lead Generation-Structure-Based Hit Evaluation and Chemistry Exploration - Xue_2016_ChemMedChem_11_497 |
| Author(s) : Xue Y , Olsson T , Johansson CA , Oster L , Beisel HG , Rohman M , Karis D , Backstrom S |
| Ref : ChemMedChem , 11 :497 , 2016 |
| Abstract : |
| PubMedSearch : Xue_2016_ChemMedChem_11_497 |
| PubMedID: 26845235 |
| Gene_locus related to this paper: human-EPHX2 |