TL-1238

more efficient inhibitor than Prostigmine

General

Type : Derivative of Neostigmine~Prostigmine, Carbamate, Ammonium

Chemical_Nomenclature : [3-(dimethylcarbamoyloxy)phenyl]-diethyl-methylazanium\;iodide

Canonical SMILES : CC[N+](C)(CC)C1=CC(=CC=C1)OC(=O)N(C)C.[I-] || CC[N+](C)(CC)C1=CC(=CC=C1)OC(=O)N(C)C

InChI : InChI=1S\/C14H23N2O2.HI\/c1-6-16(5,7-2)12-9-8-10-13(11-12)18-14(17)15(3)4\;\/h8-11H,6-7H2,1-5H3\;1H\/q+1\;\/p-1 || InChI=1S\/C14H23N2O2\/c1-6-16(5,7-2)12-9-8-10-13(11-12)18-14(17)15(3)4\/h8-11H,6-7H2,1-5H3\/q+1

InChIKey : HBVVWBFVSLUJNP-UHFFFAOYSA-M || OLPNKIILPIDARH-UHFFFAOYSA-N

Other name(s) : Substance 3393  ||  TL 1238  ||  9ASN7N3BZ5  ||  Ammonium, (3-(dimethylcarbamoyloxy)phenyl)diethylmethyl-, iodide  ||  Ammonium, diethyl(m-hydroxyphenyl)methyl-, iodide, dimethylcarbamate  ||  Diethyl(m-hydroxyphenyl)methylammonium iodide dimethylcarbamate  ||  Carbamic acid, dimethyl-, m-(diethylmethylamino)phenyl ester, iodide  ||  Carbamic acid, N,N-dimethyl-, 3-diethylaminophenyl ester, methiodide  ||  [3-(dimethylcarbamoyloxy)phenyl]-diethyl-methylazanium


MW : 378.25

Formula : C14H23IN2O2

CAS_number : 6249-65-6

PubChem : 22621,    22622

UniChem : HBVVWBFVSLUJNP-UHFFFAOYSA-M,    OLPNKIILPIDARH-UHFFFAOYSA-N

Target

References (2)

Title : Tubocurarine antagonism and inhibition of cholinesterases -
Author(s) : Blaschko H , Bulbring E , Chou TC
Ref : British Journal of Pharmacology , 4 :29 , 1949
PubMedID: 18113150

Title : The relative activity of prostigmine homologues and other substances as antagonists to tubocurarine -
Author(s) : Bulbring E , Chou TC
Ref : British Journal of Pharmacology Chemother , 2 :8 , 1947
PubMedID: 19108106