Z-Pro-Prolinal-IC4

General

Type : Benzyloxycarbonyl, Pyrrolidine, Peptide, Carboxamide, Urea derivative

Chemical_Nomenclature : (2S)-N-benzyl-2-[(2S)-2-[(1R)-1,2-dihydroxyethyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carboxamide

Canonical SMILES : C1CC(N(C1)C(=O)C2CCCN2C(=O)NCC3=CC=CC=C3)C(CO)O

InChI : InChI=1S\/C19H27N3O4\/c23-13-17(24)15-8-4-10-21(15)18(25)16-9-5-11-22(16)19(26)20-12-14-6-2-1-3-7-14\/h1-3,6-7,15-17,23-24H,4-5,8-13H2,(H,20,26)\/t15-,16-,17-\/m0\/s1

InChIKey : KPSYULVHJGJVEA-ULQDDVLXSA-N

Other name(s) : IC4  ||  2P8


MW : 361.44

Formula : C19H25N3O4

CAS_number :

PubChem : 72200812

UniChem : KPSYULVHJGJVEA-ULQDDVLXSA-N

Target

Families : Z-Pro-Prolinal-IC4 ligand of proteins in family
S9N_PPCE_Peptidase_S9

Structure :
4AN1

Protein :
pig-ppce

References (1)

Title : Molecular dynamics, crystallography and mutagenesis studies on the substrate gating mechanism of prolyl oligopeptidase. - Kaszuba_2012_Biochimie_94_1398
Author(s) : Kaszuba K , Rog T , Danne R , Canning P , Fulop V , Juhasz T , Szeltner Z , St Pierre JF , Garcia-Horsman A , Mannisto PT , Karttunen M , Hokkanen J , Bunker A
Ref : Biochimie , 94 :1398 , 2012
Abstract :
PubMedSearch : Kaszuba_2012_Biochimie_94_1398
PubMedID: 22484394
Gene_locus related to this paper: pig-ppce