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Inhibitor Report for: Laurate

Product of hydrolysis of Laurate esters


General
Type Natural, Fatty acid, Dodecanoate, Stearate, Water-insoluble medium and long chain ester
Chemical_Nomenclature dodecanoic acid
Canonical SMILES CCCCCCCCCCCC(=O)O
InChI InChI=1S/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14)
InChIKey POULHZVOKOAJMA-UHFFFAOYSA-N
Other name(s) Dodecanoate ; N-Dodecanoate ; Dodecylate ; Laurostearate ; Vulvate ; C12 fatty acid ; C12:0 ; Lauric acid ; N-Dodecanoic acid ; Dodecylic acid ; Vulvic acid
________________________________________________________________________________________________
MW|200.32
Formula|C12H24O2
CAS_number|143-07-7
PubChem|
UniChem|POULHZVOKOAJMA-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | Laurate ligand of proteins in family: Lipase_3, Pectinacetylesterase-Notum
Protein | humla-1lipa, human-NOTUM

References:
Search PubMed for references concerning: Laurate
    Title: Notum deacylates Wnt proteins to suppress signalling activity
    Kakugawa S, Langton PF, Zebisch M, Howell SA, Chang TH, Liu Y, Feizi T, Bineva G, O'Reilly N and Vincent JP <2 more author(s)>
    Ref: Nature, 519:187, 2015 : PubMed

            

    Title: Enhancement of stability of a lipase by subjecting to three phase partitioning (TPP): structures of native and TPP-treated lipase from Thermomyces lanuginosa
    Kumar M, Mukherjee J, Sinha M, Kaur P, Sharma S, Singh TP, Gupta MN
    Ref: Sustain Chem Process, 3:14, 2017 : PubMed