humla-1lipa
Thermomyces lanuginosus (Humicola lanuginosa) lipase (lip); Lipozyme TL; LIP_THELA lipolase TLL
Comment
Novozymes A\/S Lipozym TL is a 1,3 specific lipase originating from Thermomyces lanuginosus. Lipozym TL IM is an imobilized form of the enzyme on a non-compressible silica gel carrier. Lipozyme TL IM is a highly effective catalyst for interesterification and can rearrange fatty acids preferentially, but not uniquely in the 1-and 3 positions of the triglycerides. Lipozyme TL IM exhibits a high degree of substrate selectivity allowing bulky side chains\/large groups on the alcohol and acid part of the molecule. Lipozyme TL Lipolase TLL
Relationship
Family : Lipase_3
Block : L
Position in NCBI Life Tree : Thermomyces lanuginosus
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Fungi N E > Dikarya N E > Ascomycota N E > saccharomyceta N E > Pezizomycotina N E > leotiomyceta N E > Eurotiomycetes N E > Eurotiomycetidae N E > Eurotiales N E > Trichocomaceae N E > Thermomyces N E > Thermomyces lanuginosus N EMolecular evidence
No mutation
1DT3 - Humicola lanuginosa lipase in C8E5 polyoxyethylene detergent, closed lid, high ionic strength
1DT5 - Humicola lanuginosa lipase in C8E5 polyoxyethylene detergent, open lid, low ionic strength
1DTE - Humicola lanuginosa lipase in C8E5 polyoxyethylene detergent, closed lid, low ionic strength
1DU4 - Humicola lanuginosa lipase in di-C12-POC micella, closed lid, low ionic strength
1EIN - Humicola lanuginosa lipase in di-C12-POC micella, open lid, low ionic strength
1GT6 - S146A mutant of Thermomyces (Humicola) lanuginosa lipase complex with oleic acid
1TIB - Humicola lanuginosa triacylglycerol lipase
4DYH - Crystal structure of glycosylated Lipase from Humicola lanuginosa at 2 Angstrom resolution
4EA6 - Crystal structure of Fungal lipase from Thermomyces(Humicola) lanuginosa at 2.30 Angstrom resolution.
4FLF - Structure of three phase partition treated lipase from Thermomyces lanuginosa at 2.15A resolution
4GBG - Crystal structure of Ethyl acetoacetate treated lipase from Thermomyces lanuginosa at 2.9 A resolution
4GHW - Crystal structure of the complex of Fungal lipase from Thermomyces lanuginosa with decanoic acid at 2.6 A resolution
4GI1 - Structure of the complex of three phase partition treated lipase from Thermomyces lanuginosa with 16-hydroxypalmitic acid at 2.4 A resolution
4GLB - Structure of p-nitrobenzaldehyde inhibited lipase from Thermomyces lanuginosa at 2.69 A resolution.
4GWL - Structure of three phase partition treated lipase from Thermomyces lanuginosa at 2.55A resolution
4KJX - Crystal structure of the complex of three phase partition treated lipase from Thermomyces lanuginosa with Lauric acid and P-nitrobenzaldehyde (PNB) at 2.1 resolution
4N8S - Crystal Structure of the ternary complex of lipase from Thermomyces lanuginosa with Ethylacetoacetate and P-nitrobenzaldehyde at 2.3 A resolution
4S0X - Structure of three phase partition - treated lipase from Thermomyces lanuginosa in complex with lauric acid at 2.1 A resolution
4ZGB - Structure of untreated lipase from Thermomyces lanuginosa at 2.3 A resolution
5AP9 - Controlled lid-opening in Thermomyces lanuginosus lipase - a switch for activity and binding
6HW1 - Room temperature structure of lipase from T. lanuginosa at 2.5 A resolution
6O8V - The structure of lipase from Thermomyces Lanuginosa in complex with 1,3 diacylglycerol: Rhombohedral crystal form
6O9F - The structure of Thermomyces Lanuginosa lipase in complex with 1,3 diacylglycerol in a monoclinic crystal form
6OR3 - Structure of an acyl intermediate of Thermomyces Lanuginosa lipase with palmitic acid in an orthorhombic crystal
6OSZ - High Resolution Structure of the Monoclinic Form of Thermomyces Lanuginosa Lipase Complexed with Its Catalytic Products
6XOK - X-ray structure of the rhombohedral form of the lipase from Thermomyces lanuginosa at 1.3 A resolution
6XRV - X-ray structure of the monoclinic crystal form at 1.43 A resolution of lipase from Thermomyces (Humicola) lanuginosa at 173 K
6XS3 - X-ray structure of the monoclinic crystal form at 2.48 A resolution of lipase from Thermomyces (Humicola) lanuginosa at 298 K
7APN - Structure of Lipase TL from bulk agarose grown crystal
7APP - Structure of Lipase TL from capillary grown crystal in the presence of agarose
No kinetic
No disease
Sequence
Peptide
MRSSLVLFFV SAWTALASPI RREVSQDLFN QFNLFAQYSA AAYCGKNNDA PAGTNITCTG NACPEVEKAD ATFLYSFEDS GVGDVTGFLA LDNTNKLIVL SFRGSRSIEN WIGNLNFDLK EINDICSGCR GHDGFTSSWR SVADTLRQKV EDAVREHPDY RVVFTGHSLG GALATVAGAD LRGNGYDIDV FSYGAPRVGN RAFAEFLTVQ TGGTLYRITH TNDIVPRLPP REFGYSHSSP EYWIKSGTLV PVTRNDIVKI EGIDATGGNN QPNIPDIPAH LWYFGLIGTC L
References (61)
| Title : Microplate method for regioselective lipase screening with structured punicic acid triglycerides: finding Lip4 lipase as sn-2-regioselective from Candida rugosa isoforms - Ordaz_2025_Anal.Biochem__115769 |
| Author(s) : Ordaz E , Gomez-Secundino O , Guerrero-Elias HY , Camacho-Ruiz MA , Espinosa-Salgado R , Escobedo-Reyes A , Mateos-Diaz JC , Rodriguez JA |
| Ref : Analytical Biochemistry , :115769 , 2025 |
| Abstract : |
| PubMedSearch : Ordaz_2025_Anal.Biochem__115769 |
| PubMedID: 39805383 |
| Gene_locus related to this paper: canan-lipasA , canru-1lipa , canru-4lipa , human-PNLIP , humla-1lipa , rhimi-lipas |
| Title : Active Site Studies to Explain Kinetics of Lipases in Organic Solvents Using Molecular Dynamics Simulations - Tjornelund_2024_J.Phys.Chem.B__ |
| Author(s) : Tjornelund HD , Brask J , Woodley JM , Peters GHJ |
| Ref : J Phys Chem B , : , 2024 |
| Abstract : |
| PubMedSearch : Tjornelund_2024_J.Phys.Chem.B__ |
| PubMedID: 39733341 |
| Gene_locus related to this paper: canar-LipB , humla-1lipa , rhimi-lipas |
| Title : Investigating Lipase\/Stain Interactions: Determining Interfacial Protein Conformation with Surface Spectroscopy - Saeed_2024_J.Phys.Chem.B__ |
| Author(s) : Saeed KH , Strunge K , Pedersen KB , Truelsen SF , Christensen SM , Olsen L , Schiott B , Weidner T |
| Ref : J Phys Chem B , : , 2024 |
| Abstract : |
| PubMedSearch : Saeed_2024_J.Phys.Chem.B__ |
| PubMedID: 39158521 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Engineering lipase TLL to improve its acid tolerance and its biosynthesis in Trichoderma reesei for biodiesel production from acidified oil - Wang_2024_Bioresour.Technol_413_131521 |
| Author(s) : Wang F , Li Y , Wang Y , Xu X , Cao X , Cao T , Zhang W , Liu W |
| Ref : Bioresour Technol , 413 :131521 , 2024 |
| Abstract : |
| PubMedSearch : Wang_2024_Bioresour.Technol_413_131521 |
| PubMedID: 39326534 |
| Gene_locus related to this paper: humla-1lipa |
| Title : A Lipase Gene of Thermomyces lanuginosus: Sequence Analysis and High-Efficiency Expression in Pichia pastoris - Yi_2024_Int.J.Mol.Sci_25_11591 |
| Author(s) : Yi L , Cheng L , Yang Q , Luo W , Duan S |
| Ref : Int J Mol Sci , 25 :11591 , 2024 |
| Abstract : |
| PubMedSearch : Yi_2024_Int.J.Mol.Sci_25_11591 |
| PubMedID: 39519141 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Single-Particle Tracking of Thermomyces lanuginosus Lipase Reveals How Mutations in the Lid Region Remodel Its Diffusion - Iversen_2023_Biomolecules_13_631 |
| Author(s) : Iversen JF , Bohr SS , Pinholt HD , Moses ME , Iversen L , Christensen SM , Hatzakis NS , Zhang M |
| Ref : Biomolecules , 13 :631 , 2023 |
| Abstract : |
| PubMedSearch : Iversen_2023_Biomolecules_13_631 |
| PubMedID: 37189378 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Discovery of the Key Mutation Site Influencing the Thermostability of Thermomyces lanuginosus Lipase by Rosetta Design Programs - Zhu_2022_Int.J.Mol.Sci_23_ |
| Author(s) : Zhu E , Xiang X , Wan S , Miao H , Han N , Huang Z |
| Ref : Int J Mol Sci , 23 : , 2022 |
| Abstract : |
| PubMedSearch : Zhu_2022_Int.J.Mol.Sci_23_ |
| PubMedID: 36012226 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Production of Cross-Linked Lipase Crystals at a Preparative Scale - Fernandez-Penas_2021_Cryst.Growth.Des_21_1698 |
| Author(s) : Fernandez-Penas R , Verdugo-Escamilla C , Martinez-Rodriguez S , Gavira JA |
| Ref : Cryst Growth Des , 21 :1698 , 2021 |
| Abstract : |
| PubMedSearch : Fernandez-Penas_2021_Cryst.Growth.Des_21_1698 |
| PubMedID: |
| Gene_locus related to this paper: humla-1lipa |
| Title : The Crystal Structures of Thermomyces (Humicola) Lanuginosa Lipase in Complex with Enzymatic Reactants - McPherson_2020_Curr.Enzym.Inhib_16_199 |
| Author(s) : McPherson A , Larson SB , Kalasky A |
| Ref : Curr Enzym Inhib , 16 :199 , 2020 |
| Abstract : |
| PubMedSearch : McPherson_2020_Curr.Enzym.Inhib_16_199 |
| PubMedID: |
| Gene_locus related to this paper: humla-1lipa |
| Title : Cutinases as stereoselective catalysts: Specific activity and enantioselectivity of cutinases and lipases for menthol and its analogs - Su_2020_Enzyme.Microb.Technol_133_109467 |
| Author(s) : Su A , Kiokekli S , Naviwala M , Shirke AN , Pavlidis IV , Gross RA |
| Ref : Enzyme Microb Technol , 133 :109467 , 2020 |
| Abstract : |
| PubMedSearch : Su_2020_Enzyme.Microb.Technol_133_109467 |
| PubMedID: 31874689 |
| Gene_locus related to this paper: humin-cut , canar-LipB , humla-1lipa , rhimi-lipas |
| Title : Immobilization of Lipozyme TL 100L for methyl esterification of soybean oil deodorizer distillate - Zheng_2020_3.Biotech_10_51 |
| Author(s) : Zheng J , Wei W , Wang S , Li X , Zhang Y , Wang Z |
| Ref : 3 Biotech , 10 :51 , 2020 |
| Abstract : |
| PubMedSearch : Zheng_2020_3.Biotech_10_51 |
| PubMedID: 32002342 |
| Gene_locus related to this paper: humla-1lipa |
| Title : A simple and versatile microfluidic device for efficient biomacromolecule crystallization and structural analysis by serial crystallography - de Wijn_2019_IUCrJ_6_454 |
| Author(s) : de Wijn R , Hennig O , Roche J , Engilberge S , Rollet K , Fernandez-Millan P , Brillet K , Betat H , Morl M , Roussel A , Girard E , Mueller-Dieckmann C , Fox GC , Olieric V , Gavira JA , Lorber B , Sauter C |
| Ref : IUCrJ , 6 :454 , 2019 |
| Abstract : |
| PubMedSearch : de Wijn_2019_IUCrJ_6_454 |
| PubMedID: 31098026 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Direct observation of Thermomyces lanuginosus lipase diffusional states by Single Particle Tracking and their remodeling by mutations and inhibition - Bohr_2019_Sci.Rep_9_16169 |
| Author(s) : Bohr SS , Lund PM , Kallenbach AS , Pinholt H , Thomsen J , Iversen L , Svendsen A , Christensen SM , Hatzakis NS |
| Ref : Sci Rep , 9 :16169 , 2019 |
| Abstract : |
| PubMedSearch : Bohr_2019_Sci.Rep_9_16169 |
| PubMedID: 31700110 |
| Gene_locus related to this paper: humla-1lipa |
| Title : N-terminal domain replacement changes an archaeal monoacylglycerol lipase into a triacylglycerol lipase - Soni_2019_Biotechnol.Biofuels_12_110 |
| Author(s) : Soni S , Sathe SS , Sheth RR , Tiwari P , Vadgama RN , Odaneth AA , Lali AM , Chandrayan SK |
| Ref : Biotechnol Biofuels , 12 :110 , 2019 |
| Abstract : |
| PubMedSearch : Soni_2019_Biotechnol.Biofuels_12_110 |
| PubMedID: 31080517 |
| Gene_locus related to this paper: humla-1lipa , theon-b6ywd5 |
| Title : Monomyristin and Monopalmitin Derivatives: Synthesis and Evaluation as Potential Antibacterial and Antifungal Agents - Jumina_2018_Molecules_23_ |
| Author(s) : Jumina J , Nurmala A , Fitria A , Pranowo D , Sholikhah EN , Kurniawan YS , Kuswandi B |
| Ref : Molecules , 23 : , 2018 |
| Abstract : |
| PubMedSearch : Jumina_2018_Molecules_23_ |
| PubMedID: 30501124 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Enhancement of stability of a lipase by subjecting to three phase partitioning (TPP): structures of native and TPP-treated lipase from Thermomyces lanuginosa - Kumar_2015_Sustain.Chem.Process_3_14 |
| Author(s) : Kumar M , Mukherjee J , Sinha M , Kaur P , Sharma S , Singh TP , Gupta MN |
| Ref : Sustain Chem Process , 3 :14 , 2017 |
| Abstract : |
| PubMedSearch : Kumar_2015_Sustain.Chem.Process_3_14 |
| PubMedID: |
| Gene_locus related to this paper: humla-1lipa |
| Title : Efficient kinetic resolution of (+\/-)-menthol by a lipase from Thermomyces lanuginosus - De Yan_2017_Biotechnol.Appl.Biochem_64_87 |
| Author(s) : De Yan H , Li Q , Wang Z |
| Ref : Biotechnol Appl Biochem , 64 :87 , 2017 |
| Abstract : |
| PubMedSearch : De Yan_2017_Biotechnol.Appl.Biochem_64_87 |
| PubMedID: 26549685 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Lipases That Activate at High Solvent Polarities - Skjold-Jorgensen_2016_Biochemistry_55_146 |
| Author(s) : Skjold-Jorgensen J , Vind J , Svendsen A , Bjerrum MJ |
| Ref : Biochemistry , 55 :146 , 2016 |
| Abstract : |
| PubMedSearch : Skjold-Jorgensen_2016_Biochemistry_55_146 |
| PubMedID: 26645098 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Controlled lid-opening in Thermomyces lanuginosus lipase- An engineered switch for studying lipase function - Skjold-Jorgensen_2016_Biochim.Biophys.Acta_1865_20 |
| Author(s) : Skjold-Jorgensen J , Vind J , Moroz OV , Blagova E , Bhatia VK , Svendsen A , Wilson KS , Bjerrum MJ |
| Ref : Biochimica & Biophysica Acta , 1865 :20 , 2016 |
| Abstract : |
| PubMedSearch : Skjold-Jorgensen_2016_Biochim.Biophys.Acta_1865_20 |
| PubMedID: 27693248 |
| Gene_locus related to this paper: humla-1lipa |
| Title : High-yield synthesis of bioactive ethyl cinnamate by enzymatic esterification of cinnamic acid - Wang_2016_Food.Chem_190_629 |
| Author(s) : Wang Y , Zhang DH , Zhang JY , Chen N , Zhi GY |
| Ref : Food Chem , 190 :629 , 2016 |
| Abstract : |
| PubMedSearch : Wang_2016_Food.Chem_190_629 |
| PubMedID: 26213020 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Promoting protein self-association in non-glycosylated Thermomyces lanuginosus lipase based on crystal lattice contacts - Madsen_2015_Biochim.Biophys.Acta_1854_1914 |
| Author(s) : Madsen JK , Sorensen TR , Kaspersen JD , Silow MB , Vind J , Pedersen JS , Svendsen A , Otzen DE |
| Ref : Biochimica & Biophysica Acta , 1854 :1914 , 2015 |
| Abstract : |
| PubMedSearch : Madsen_2015_Biochim.Biophys.Acta_1854_1914 |
| PubMedID: 26431886 |
| Gene_locus related to this paper: humla-1lipa |
| Title : First chemoenzymatic stereodivergent synthesis of both enantiomers of promethazine and ethopropazine - Borowiecki_2014_Beilstein.J.Org.Chem_10_3038 |
| Author(s) : Borowiecki P , Paprocki D , Dranka M |
| Ref : Beilstein J Org Chem , 10 :3038 , 2014 |
| Abstract : |
| PubMedSearch : Borowiecki_2014_Beilstein.J.Org.Chem_10_3038 |
| PubMedID: 25670974 |
| Gene_locus related to this paper: canar-LipB , humla-1lipa |
| Title : Altering the activation mechanism in Thermomyces lanuginosus lipase - Skjold-Jorgensen_2014_Biochemistry_53_4152 |
| Author(s) : Skjold-Jorgensen J , Vind J , Svendsen A , Bjerrum MJ |
| Ref : Biochemistry , 53 :4152 , 2014 |
| Abstract : |
| PubMedSearch : Skjold-Jorgensen_2014_Biochemistry_53_4152 |
| PubMedID: 24870718 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Thermomyces lanuginosus Lipase with Closed Lid Catalyzes Elimination of Acetic Acid from 11-Acetyl-Prostaglandin E2 - Villo_2014_ChemCatChem_6_1998 |
| Author(s) : Villo L , Metsala A , Tamp S , Parve J , Vallikivi I , Jarving I , Samel N , Lille U , Pehk T , Parve O |
| Ref : ChemCatChem , 6 :1998 , 2014 |
| Abstract : |
| PubMedSearch : Villo_2014_ChemCatChem_6_1998 |
| PubMedID: |
| Gene_locus related to this paper: humla-1lipa |
| Title : Key residues responsible for enhancement of catalytic efficiency of Thermomyces lanuginosus lipase Lip revealed by complementary protein engineering strategy - Li_2014_J.Biotechnol_188C_29 |
| Author(s) : Li XJ , Zheng RC , Ma HY , Huang JF , Zheng YG |
| Ref : J Biotechnol , 188C :29 , 2014 |
| Abstract : |
| PubMedSearch : Li_2014_J.Biotechnol_188C_29 |
| PubMedID: 25116359 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Thermophilic esterase from Thermomyces lanuginosus: molecular cloning, functional expression and biochemical characterization - Li_2014_Protein.Expr.Purif_101_1 |
| Author(s) : Li XJ , Zheng RC , Wu ZM , Ding X , Zheng YG |
| Ref : Protein Expr Purif , 101 :1 , 2014 |
| Abstract : |
| PubMedSearch : Li_2014_Protein.Expr.Purif_101_1 |
| PubMedID: 24859676 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Optimized butyl butyrate synthesis catalyzed by Thermomyces lanuginosus lipase - Martins_2013_Biotechnol.Prog_29_1416 |
| Author(s) : Martins AB , Friedrich JL , Rodrigues RC , Garcia-Galan C , Fernandez-Lafuente R , Ayub MA |
| Ref : Biotechnol Prog , 29 :1416 , 2013 |
| Abstract : |
| PubMedSearch : Martins_2013_Biotechnol.Prog_29_1416 |
| PubMedID: 23946156 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Improved production of butyl butyrate with lipase from Thermomyces lanuginosus immobilized on styrene-divinylbenzene beads - Martins_2013_Bioresour.Technol_134_417 |
| Author(s) : Martins AB , Friedrich JL , Cavalheiro JC , Garcia-Galan C , Barbosa O , Ayub MA , Fernandez-Lafuente R , Rodrigues RC |
| Ref : Bioresour Technol , 134 :417 , 2013 |
| Abstract : |
| PubMedSearch : Martins_2013_Bioresour.Technol_134_417 |
| PubMedID: 23499180 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Variant of the Thermomyces lanuginosus lipase with improved kinetic stability: A candidate for enzyme replacement therapy - Wang_2013_Biophys.Chem_172C_43 |
| Author(s) : Wang H , Hagedorn J , Svendsen A , Borch K , Otzen DE |
| Ref : Biophysical Chemistry , 172C :43 , 2013 |
| Abstract : |
| PubMedSearch : Wang_2013_Biophys.Chem_172C_43 |
| PubMedID: 23357413 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Novel and highly efficient regioselective route to helicid esters by lipozyme TLL - Yang_2013_PLoS.One_8_e80715 |
| Author(s) : Yang R , Zhao X , Liu X |
| Ref : PLoS ONE , 8 :e80715 , 2013 |
| Abstract : |
| PubMedSearch : Yang_2013_PLoS.One_8_e80715 |
| PubMedID: 24278310 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Kinetic biosynthesis of L-ascorbyl acetate by immobilized Thermomyces lanuginosus lipase (Lipozyme TLIM) - Zhang_2011_Bioprocess.Biosyst.Eng_34_1163 |
| Author(s) : Zhang DH , Lv YQ , Zhi GY , Yuwen LX |
| Ref : Bioprocess Biosyst Eng , 34 :1163 , 2011 |
| Abstract : |
| PubMedSearch : Zhang_2011_Bioprocess.Biosyst.Eng_34_1163 |
| PubMedID: 21744121 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Ionic strength-dependent denaturation of Thermomyces lanuginosus lipase induced by SDS - Fano_2011_Arch.Biochem.Biophys_506_92 |
| Author(s) : Fano M , van de Weert M , Moeller EH , Kruse NA , Frokjaer S |
| Ref : Archives of Biochemistry & Biophysics , 506 :92 , 2011 |
| Abstract : |
| PubMedSearch : Fano_2011_Arch.Biochem.Biophys_506_92 |
| PubMedID: 21093408 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Study of Soybean Oil Hydrolysis Catalyzed by Thermomyces lanuginosus Lipase and Its Application to Biodiesel Production via Hydroesterification - Cavalcanti-Oliveira_2010_Enzyme.Res_2011_618692 |
| Author(s) : Cavalcanti-Oliveira E , da Silva PR , Ramos AP , Aranda DA , Freire DM |
| Ref : Enzyme Res , 2011 :618692 , 2010 |
| Abstract : |
| PubMedSearch : Cavalcanti-Oliveira_2010_Enzyme.Res_2011_618692 |
| PubMedID: 21052517 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Influence of glycosylation on the adsorption of Thermomyces lanuginosus lipase to hydrophobic and hydrophilic surfaces - Pinholt_2010_Eur.J.Pharm.Sci_40_273 |
| Author(s) : Pinholt C , Fano M , Wiberg C , Hostrup S , Bukrinsky JT , Frokjaer S , Norde W , Jorgensen L |
| Ref : Eur J Pharm Sci , 40 :273 , 2010 |
| Abstract : |
| PubMedSearch : Pinholt_2010_Eur.J.Pharm.Sci_40_273 |
| PubMedID: 20380877 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Improved enzymatic activity of Thermomyces lanuginosus lipase immobilized in a hydrophobic particulate mesoporous carrier - Sorensen_2010_J.Colloid.Interface.Sci_343_359 |
| Author(s) : Sorensen MH , Ng JB , Bergstrom L , Alberius PC |
| Ref : J Colloid Interface Sci , 343 :359 , 2010 |
| Abstract : |
| PubMedSearch : Sorensen_2010_J.Colloid.Interface.Sci_343_359 |
| PubMedID: 20022021 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Thermomyces lanuginosus lipase-catalyzed regioselective acylation of nucleosides: Enzyme substrate recognition - Li_2009_J.Biotechnol_140_250 |
| Author(s) : Li N , Zong MH , Ma D |
| Ref : J Biotechnol , 140 :250 , 2009 |
| Abstract : |
| PubMedSearch : Li_2009_J.Biotechnol_140_250 |
| PubMedID: 19428721 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Improved reactivation of immobilized-stabilized lipase from Thermomyces lanuginosus by its coating with highly hydrophilic polymers - Rodrigues_2009_J.Biotechnol_144_113 |
| Author(s) : Rodrigues RC , Bolivar JM , Volpato G , Filice M , Godoy C , Fernandez-Lafuente R , Guisan JM |
| Ref : J Biotechnol , 144 :113 , 2009 |
| Abstract : |
| PubMedSearch : Rodrigues_2009_J.Biotechnol_144_113 |
| PubMedID: 19737586 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Fatty acid selectivity of lipases during acidolysis reaction between oleic acid and monoacid triacylglycerols - Karabulut_2009_J.Agric.Food.Chem_57_10466 |
| Author(s) : Karabulut I , Durmaz G , Hayaloglu AA |
| Ref : Journal of Agricultural and Food Chemistry , 57 :10466 , 2009 |
| Abstract : |
| PubMedSearch : Karabulut_2009_J.Agric.Food.Chem_57_10466 |
| PubMedID: 19835376 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Thermomyces lanuginosus lipase in the liquid-crystalline phases of aqueous phytantriol: X-ray diffraction and vibrational spectroscopic studies - Misiunas_2008_Biophys.Chem_134_144 |
| Author(s) : Misiunas A , Talaikyte Z , Niaura G , Razumas V , Nylander T |
| Ref : Biophysical Chemistry , 134 :144 , 2008 |
| Abstract : |
| PubMedSearch : Misiunas_2008_Biophys.Chem_134_144 |
| PubMedID: 18329781 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Differential adsorption of variants of the Thermomyces lanuginosus lipase on a hydrophobic surface suggests a role for local flexibility - Otzen_2008_Colloids.Surf.B.Biointerfaces_64_223 |
| Author(s) : Otzen D |
| Ref : Colloids Surf B Biointerfaces , 64 :223 , 2008 |
| Abstract : |
| PubMedSearch : Otzen_2008_Colloids.Surf.B.Biointerfaces_64_223 |
| PubMedID: 18321685 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Adsorption and activity of Thermomyces lanuginosus lipase on hydrophobic and hydrophilic surfaces measured with dual polarization interferometry (DPI) and confocal microscopy - Sonesson_2008_Colloids.Surf.B.Biointerfaces_61_208 |
| Author(s) : Sonesson AW , Callisen TH , Brismar H , Elofsson UM |
| Ref : Colloids Surf B Biointerfaces , 61 :208 , 2008 |
| Abstract : |
| PubMedSearch : Sonesson_2008_Colloids.Surf.B.Biointerfaces_61_208 |
| PubMedID: 17890066 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Improvement of biodiesel production by lipozyme TL IM-catalyzed methanolysis using response surface methodology and acyl migration enhancer - Wang_2008_Bioresour.Technol_99_7232 |
| Author(s) : Wang Y , Wu H , Zong MH |
| Ref : Bioresour Technol , 99 :7232 , 2008 |
| Abstract : |
| PubMedSearch : Wang_2008_Bioresour.Technol_99_7232 |
| PubMedID: 18262410 |
| Gene_locus related to this paper: humla-1lipa |
| Title : A comparative study on two fungal lipases from Thermomyces lanuginosus and Yarrowia lipolytica shows the combined effects of detergents and pH on lipase adsorption and activity - Aloulou_2007_Biochim.Biophys.Acta_1771_1446 |
| Author(s) : Aloulou A , Puccinelli D , de Caro A , Leblond Y , Carriere F |
| Ref : Biochimica & Biophysica Acta , 1771 :1446 , 2007 |
| Abstract : |
| PubMedSearch : Aloulou_2007_Biochim.Biophys.Acta_1771_1446 |
| PubMedID: 18022403 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Mobility of Thermomyces lanuginosus lipase on a trimyristin substrate surface - Sonesson_2007_Langmuir_23_2706 |
| Author(s) : Sonesson AW , Brismar H , Callisen TH , Elofsson UM |
| Ref : Langmuir , 23 :2706 , 2007 |
| Abstract : |
| PubMedSearch : Sonesson_2007_Langmuir_23_2706 |
| PubMedID: 17261037 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Activation, inhibition, and destabilization of Thermomyces lanuginosus lipase by detergents - Mogensen_2005_Biochemistry_44_1719 |
| Author(s) : Mogensen JE , Sehgal P , Otzen DE |
| Ref : Biochemistry , 44 :1719 , 2005 |
| Abstract : |
| PubMedSearch : Mogensen_2005_Biochemistry_44_1719 |
| PubMedID: 15683256 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Implications of surface charge and curvature for the binding orientation of Thermomyces lanuginosus lipase on negatively charged or zwitterionic phospholipid vesicles as studied by ESR spectroscopy - Hedin_2005_Biochemistry_44_16658 |
| Author(s) : Hedin EM , Hoyrup P , Patkar SA , Vind J , Svendsen A , Hult K |
| Ref : Biochemistry , 44 :16658 , 2005 |
| Abstract : |
| PubMedSearch : Hedin_2005_Biochemistry_44_16658 |
| PubMedID: 16342956 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Interfacial orientation of Thermomyces lanuginosa lipase on phospholipid vesicles investigated by electron spin resonance relaxation spectroscopy - Hedin_2002_Biochemistry_41_14185 |
| Author(s) : Hedin EM , Hoyrup P , Patkar SA , Vind J , Svendsen A , Fransson L , Hult K |
| Ref : Biochemistry , 41 :14185 , 2002 |
| Abstract : |
| PubMedSearch : Hedin_2002_Biochemistry_41_14185 |
| PubMedID: 12450382 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Binding of Thermomyces (Humicola) lanuginosa lipase to the mixed micelles of cis-parinaric acid\/NaTDC - Yapoudjian_2002_Eur.J.Biochem_269_1613 |
| Author(s) : Yapoudjian S , Ivanova MG , Brzozowski AM , Patkar SA , Vind J , Svendsen A , Verger R |
| Ref : European Journal of Biochemistry , 269 :1613 , 2002 |
| Abstract : |
| PubMedSearch : Yapoudjian_2002_Eur.J.Biochem_269_1613 |
| PubMedID: 11895431 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Impact of the tryptophan residues of Humicola lanuginosa lipase on its thermal stability - Zhu_2001_Biochim.Biophys.Acta_1547_329 |
| Author(s) : Zhu K , Jutila A , Tuominen EK , Patkar SA , Svendsen A , Kinnunen PK |
| Ref : Biochimica & Biophysica Acta , 1547 :329 , 2001 |
| Abstract : |
| PubMedSearch : Zhu_2001_Biochim.Biophys.Acta_1547_329 |
| PubMedID: 11410289 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Effect of the lipid interface on the catalytic activity and spectroscopic properties of a fungal lipase - Cajal_2000_Biochimie_82_1053 |
| Author(s) : Cajal Y , Svendsen A , De Bolos J , Patkar SA , Alsina MA |
| Ref : Biochimie , 82 :1053 , 2000 |
| Abstract : |
| PubMedSearch : Cajal_2000_Biochimie_82_1053 |
| PubMedID: 11099802 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Detergent-induced conformational changes of Humicola lanuginosa lipase studied by fluorescence spectroscopy - Jutila_2000_Biophys.J_78_1634 |
| Author(s) : Jutila A , Zhu K , Patkar SA , Vind J , Svendsen A , Kinnunen PK |
| Ref : Biophysical Journal , 78 :1634 , 2000 |
| Abstract : |
| PubMedSearch : Jutila_2000_Biophys.J_78_1634 |
| PubMedID: 10692347 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Interfacial control of lid opening in Thermomyces lanuginosa lipase - Cajal_2000_Biochemistry_39_413 |
| Author(s) : Cajal Y , Svendsen A , Girona V , Patkar SA , Alsina MA |
| Ref : Biochemistry , 39 :413 , 2000 |
| Abstract : |
| PubMedSearch : Cajal_2000_Biochemistry_39_413 |
| PubMedID: 10631003 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Structural origins of the interfacial activation in Thermomyces (Humicola) lanuginosa lipase - Brzozowski_2000_Biochemistry_39_15071 |
| Author(s) : Brzozowski AM , Savage H , Verma CS , Turkenburg JP , Lawson DM , Svendsen A , Patkar S |
| Ref : Biochemistry , 39 :15071 , 2000 |
| Abstract : |
| PubMedSearch : Brzozowski_2000_Biochemistry_39_15071 |
| PubMedID: 11106485 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Active serine involved in the stabilization of the active site loop in the Humicola lanuginosa lipase - Peters_1998_Biochemistry_37_12375 |
| Author(s) : Peters GH , Svendsen A , Langberg H , Vind J , Patkar SA , Toxvaerd S , Kinnunen PK |
| Ref : Biochemistry , 37 :12375 , 1998 |
| Abstract : |
| PubMedSearch : Peters_1998_Biochemistry_37_12375 |
| PubMedID: 9730809 |
| Gene_locus related to this paper: humla-1lipa |
| Title : The role of Glu87 and Trp89 in the lid of Humicola lanuginosa lipase - Martinelle_1996_Protein.Eng_9_519 |
| Author(s) : Martinelle M , Holmquist M , Clausen IG , Patkar S , Svendsen A , Hult K |
| Ref : Protein Engineering , 9 :519 , 1996 |
| Abstract : |
| PubMedSearch : Martinelle_1996_Protein.Eng_9_519 |
| PubMedID: 8862552 |
| Gene_locus related to this paper: humla-1lipa |
| Title : The importance of non-charged amino acids in antibody binding to Humicola lanuginosa lipase - Naver_1995_Scand.J.Immunol_41_443 |
| Author(s) : Naver H , Lovborg U |
| Ref : Scand J Immunol , 41 :443 , 1995 |
| Abstract : |
| PubMedSearch : Naver_1995_Scand.J.Immunol_41_443 |
| PubMedID: 7536956 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Probing a functional role of Glu87 and Trp89 in the lid of Humicola lanuginosa lipase through transesterification reactions in organic solvent - Holmquist_1995_J.Protein.Chem_14_217 |
| Author(s) : Holmquist M , Clausen IG , Patkar S , Svendsen A , Hult K |
| Ref : J Protein Chem , 14 :217 , 1995 |
| Abstract : |
| PubMedSearch : Holmquist_1995_J.Protein.Chem_14_217 |
| PubMedID: 7662109 |
| Gene_locus related to this paper: humla-1lipa |
| Title : Conformational lability of lipases observed in the absence of an oil-water interface: crystallographic studies of enzymes from the fungi Humicola lanuginosa and Rhizopus delemar - Derewenda_1994_J.Lipid.Res_35_524 |
| Author(s) : Derewenda U , Swenson L , Wei Y , Green R , Kobos PM , Joerger R , Haas MJ , Derewenda ZS |
| Ref : J Lipid Res , 35 :524 , 1994 |
| Abstract : |
| PubMedSearch : Derewenda_1994_J.Lipid.Res_35_524 |
| PubMedID: 8014587 |
| Gene_locus related to this paper: humla-1lipa , rhidl-lipas |
| Title : An unusual buried polar cluster in a family of fungal lipases - Derewenda_1994_Nat.Struct.Biol_1_36 |
| Author(s) : Derewenda U , Swenson L , Green R , Wei Y , Dodson GG , Yamaguchi S , Haas MJ , Derewenda ZS |
| Ref : Nat Struct Biol , 1 :36 , 1994 |
| Abstract : |
| PubMedSearch : Derewenda_1994_Nat.Struct.Biol_1_36 |
| PubMedID: 7656005 |
| Gene_locus related to this paper: humla-1lipa , penca-mdgli , rhidl-lipas |
| Title : Current progress in crystallographic studies of new lipases from filamentous fungi - Derewenda_1994_Protein.Eng_7_551 |
| Author(s) : Derewenda U , Swenson L , Green R , Wei Y , Yamaguchi S , Joerger R , Haas MJ , Derewenda ZS |
| Ref : Protein Engineering , 7 :551 , 1994 |
| Abstract : |
| PubMedSearch : Derewenda_1994_Protein.Eng_7_551 |
| PubMedID: 8029211 |
| Gene_locus related to this paper: humla-1lipa , penca-mdgli , rhidl-lipas |
| Title : Trp89 in the lid of Humicola lanuginosa lipase is important for efficient hydrolysis of tributyrin - Holmquist_1994_Lipids_29_599 |
| Author(s) : Holmquist M , Martinelle M , Clausen IG , Patkar S , Svendsen A , Hult K |
| Ref : Lipids , 29 :599 , 1994 |
| Abstract : |
| PubMedSearch : Holmquist_1994_Lipids_29_599 |
| PubMedID: 7815893 |
| Gene_locus related to this paper: humla-1lipa |