F455W_cultr-ACHE1

General

Gene Locus : cultr-ACHE1

Mode of mutation : Natural mutant

Disease :

Summary : OP-resistance resistant strain TYM 870-fold decrease in fenitroxon-sensitivity Nabeshima_2004_Biochem.Biophys.Res.Commun_313_794 || OP-resistance F331W substitution in resistant C. tritaeniorhynchus in china Alout_2007_J.Med.Entomol_44_463 || OP-resistance F331W substitution in all strains C. tritaeniorhynchus in china Wu_2016_J.Am.Mosq.Control.Assoc_32_144

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : OP-resistance

Torpedo_number : 331

Kinetic Parameter : No kinetic parameter

News : JUNE-08-2007, JANUARY-09-2004

Comment :
p.F455W Phe455Trp also called F331W with torpedo numbering. Contradictory results for insecticide resistance see ALout 2007 Wu 2016

References (5)

Title : Detection of target site mutations in the acetylcholinesterase and voltage-gated sodium channel in field populations of Culex quinquefasciatus and Cx. tritaeniorhynchus from southern Sichuan region of China - Liu_2023_J.Am.Mosq.Control.Assoc__
Author(s) : Liu J , Wang Y , Liu P , Yu X , Tan AI , Zeng J , Li L , Qiu X
Ref : J Am Mosq Control Assoc , : , 2023
PubMedID: 36752737

Title : Multiple-Insecticide Resistance and Classic Gene Mutations to Japanese Encephalitis Vector Culex tritaeniorhynchus from China - Wu_2016_J.Am.Mosq.Control.Assoc_32_144
Author(s) : Wu ZM , Chu HL , Wang G , Zhu XJ , Guo XX , Zhang YM , Xing D , Yan T , Zhao MH , Dong YD , Li CX , Zhao TY
Ref : J Am Mosq Control Assoc , 32 :144 , 2016
PubMedID: 27280353

Title : Malathion Resistance Status and Mutations in Acetylcholinesterase Gene (Ace) in Japanese Encephalitis and Filariasis Vectors from Endemic Area in India - Misra_2015_J.Med.Entomol_52_442
Author(s) : Misra BR , Gore M
Ref : Journal of Medical Entomology , 52 :442 , 2015
PubMedID: 26334819

Title : Different amino-acid substitutions confer insecticide resistance through acetylcholinesterase 1 insensitivity in Culex vishnui and Culex tritaeniorhynchus (Diptera: Culicidae) from China - Alout_2007_J.Med.Entomol_44_463
Author(s) : Alout H , Berthomieu A , Cui F , Tan Y , Berticat C , Qiao C , Weill M
Ref : Journal of Medical Entomology , 44 :463 , 2007
PubMedID: 17547232
Gene_locus related to this paper: culpi-ACHE1

Title : An amino acid substitution attributable to insecticide-insensitivity of acetylcholinesterase in a Japanese encephalitis vector mosquito, Culex tritaeniorhynchus - Nabeshima_2004_Biochem.Biophys.Res.Commun_313_794
Author(s) : Nabeshima T , Mori A , Kozaki T , Iwata Y , Hidoh O , Harada S , Kasai S , Severson DW , Kono Y , Tomita T
Ref : Biochemical & Biophysical Research Communications , 313 :794 , 2004
PubMedID: 14697262
Gene_locus related to this paper: cultr-ACHE1 , cultr-ACHE2