Fritz-Laylin_2010_Cell_140_631

Reference

Title : The genome of Naegleria gruberi illuminates early eukaryotic versatility - Fritz-Laylin_2010_Cell_140_631
Author(s) : Fritz-Laylin LK , Prochnik SE , Ginger ML , Dacks JB , Carpenter ML , Field MC , Kuo A , Paredez A , Chapman J , Pham J , Shu S , Neupane R , Cipriano M , Mancuso J , Tu H , Salamov A , Lindquist E , Shapiro H , Lucas S , Grigoriev IV , Cande WZ , Fulton C , Rokhsar DS , Dawson SC
Ref : Cell , 140 :631 , 2010
Abstract :

Genome sequences of diverse free-living protists are essential for understanding eukaryotic evolution and molecular and cell biology. The free-living amoeboflagellate Naegleria gruberi belongs to a varied and ubiquitous protist clade (Heterolobosea) that diverged from other eukaryotic lineages over a billion years ago. Analysis of the 15,727 protein-coding genes encoded by Naegleria's 41 Mb nuclear genome indicates a capacity for both aerobic respiration and anaerobic metabolism with concomitant hydrogen production, with fundamental implications for the evolution of organelle metabolism. The Naegleria genome facilitates substantially broader phylogenomic comparisons of free-living eukaryotes than previously possible, allowing us to identify thousands of genes likely present in the pan-eukaryotic ancestor, with 40% likely eukaryotic inventions. Moreover, we construct a comprehensive catalog of amoeboid-motility genes. The Naegleria genome, analyzed in the context of other protists, reveals a remarkably complex ancestral eukaryote with a rich repertoire of cytoskeletal, sexual, signaling, and metabolic modules.

PubMedSearch : Fritz-Laylin_2010_Cell_140_631
PubMedID: 20211133
Gene_locus related to this paper: naegr-d2ux86 , naegr-d2uyl7 , naegr-d2uyn1 , naegr-d2uzk6 , naegr-d2uzp4 , naegr-d2v1m1 , naegr-d2v3p5 , naegr-d2v5p1 , naegr-d2v6f6 , naegr-d2v6y9 , naegr-d2v8x8 , naegr-d2v186 , naegr-d2v339 , naegr-d2v556 , naegr-d2vbq7 , naegr-d2vdq6 , naegr-d2ve51 , naegr-d2vga2 , naegr-d2vgm9 , naegr-d2vh14 , naegr-d2vha2 , naegr-d2vj80 , naegr-d2vjj7 , naegr-d2vl41 , naegr-d2vmj5 , naegr-d2vms7 , naegr-d2vqi5 , naegr-d2vr44 , naegr-d2vrq2 , naegr-d2vs01 , naegr-d2vs58 , naegr-d2vts5 , naegr-d2vu69 , naegr-d2vvg8 , naegr-d2vxp2 , naegr-d2vyl1 , naegr-d2vzy5 , naegr-d2w0l5 , naegr-d2w0v9 , naegr-d2w3g8 , naegr-d2w3v7 , naegr-d2w3v8 , naegr-d2vct1

Related information

Gene_locus naegr-d2ux86    naegr-d2uyl7    naegr-d2uyn1    naegr-d2uzk6    naegr-d2uzp4    naegr-d2v1m1    naegr-d2v3p5    naegr-d2v5p1    naegr-d2v6f6    naegr-d2v6y9    naegr-d2v8x8    naegr-d2v186    naegr-d2v339    naegr-d2v556    naegr-d2vbq7    naegr-d2vdq6    naegr-d2ve51    naegr-d2vga2    naegr-d2vgm9    naegr-d2vh14    naegr-d2vha2    naegr-d2vj80    naegr-d2vjj7    naegr-d2vl41    naegr-d2vmj5    naegr-d2vms7    naegr-d2vqi5    naegr-d2vr44    naegr-d2vrq2    naegr-d2vs01    naegr-d2vs58    naegr-d2vts5    naegr-d2vu69    naegr-d2vvg8    naegr-d2vxp2    naegr-d2vyl1    naegr-d2vzy5    naegr-d2w0l5    naegr-d2w0v9    naegr-d2w3g8    naegr-d2w3v7    naegr-d2w3v8    naegr-d2vct1
Gene_locus_frgt naegr-d2vcf2    naegr-d2w3x5    naegr-d2w5n1

Citations formats

Fritz-Laylin LK, Prochnik SE, Ginger ML, Dacks JB, Carpenter ML, Field MC, Kuo A, Paredez A, Chapman J, Pham J, Shu S, Neupane R, Cipriano M, Mancuso J, Tu H, Salamov A, Lindquist E, Shapiro H, Lucas S, Grigoriev IV, Cande WZ, Fulton C, Rokhsar DS, Dawson SC (2010)
The genome of Naegleria gruberi illuminates early eukaryotic versatility
Cell 140 :631

Fritz-Laylin LK, Prochnik SE, Ginger ML, Dacks JB, Carpenter ML, Field MC, Kuo A, Paredez A, Chapman J, Pham J, Shu S, Neupane R, Cipriano M, Mancuso J, Tu H, Salamov A, Lindquist E, Shapiro H, Lucas S, Grigoriev IV, Cande WZ, Fulton C, Rokhsar DS, Dawson SC (2010)
Cell 140 :631