Lindquist E

References (38)

Title : Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus - de Vries_2017_Genome.Biol_18_28
Author(s) : de Vries RP , Riley R , Wiebenga A , Aguilar-Osorio G , Amillis S , Uchima CA , Anderluh G , Asadollahi M , Askin M , Barry K , Battaglia E , Bayram O , Benocci T , Braus-Stromeyer SA , Caldana C , Canovas D , Cerqueira GC , Chen F , Chen W , Choi C , Clum A , Dos Santos RA , Damasio AR , Diallinas G , Emri T , Fekete E , Flipphi M , Freyberg S , Gallo A , Gournas C , Habgood R , Hainaut M , Harispe ML , Henrissat B , Hilden KS , Hope R , Hossain A , Karabika E , Karaffa L , Karanyi Z , Krasevec N , Kuo A , Kusch H , LaButti K , Lagendijk EL , Lapidus A , Levasseur A , Lindquist E , Lipzen A , Logrieco AF , Maccabe A , Makela MR , Malavazi I , Melin P , Meyer V , Mielnichuk N , Miskei M , Molnar AP , Mule G , Ngan CY , Orejas M , Orosz E , Ouedraogo JP , Overkamp KM , Park HS , Perrone G , Piumi F , Punt PJ , Ram AF , Ramon A , Rauscher S , Record E , Riano-Pachon DM , Robert V , Rohrig J , Ruller R , Salamov A , Salih NS , Samson RA , Sandor E , Sanguinetti M , Schutze T , Sepcic K , Shelest E , Sherlock G , Sophianopoulou V , Squina FM , Sun H , Susca A , Todd RB , Tsang A , Unkles SE , van de Wiele N , van Rossen-Uffink D , Oliveira JV , Vesth TC , Visser J , Yu JH , Zhou M , Andersen MR , Archer DB , Baker SE , Benoit I , Brakhage AA , Braus GH , Fischer R , Frisvad JC , Goldman GH , Houbraken J , Oakley B , Pocsi I , Scazzocchio C , Seiboth B , vanKuyk PA , Wortman J , Dyer PS , Grigoriev IV
Ref : Genome Biol , 18 :28 , 2017
Abstract : BACKGROUND: The fungal genus Aspergillus is of critical importance to humankind. Species include those with industrial applications, important pathogens of humans, animals and crops, a source of potent carcinogenic contaminants of food, and an important genetic model. The genome sequences of eight aspergilli have already been explored to investigate aspects of fungal biology, raising questions about evolution and specialization within this genus. RESULTS: We have generated genome sequences for ten novel, highly diverse Aspergillus species and compared these in detail to sister and more distant genera. Comparative studies of key aspects of fungal biology, including primary and secondary metabolism, stress response, biomass degradation, and signal transduction, revealed both conservation and diversity among the species. Observed genomic differences were validated with experimental studies. This revealed several highlights, such as the potential for sex in asexual species, organic acid production genes being a key feature of black aspergilli, alternative approaches for degrading plant biomass, and indications for the genetic basis of stress response. A genome-wide phylogenetic analysis demonstrated in detail the relationship of the newly genome sequenced species with other aspergilli. CONCLUSIONS: Many aspects of biological differences between fungal species cannot be explained by current knowledge obtained from genome sequences. The comparative genomics and experimental study, presented here, allows for the first time a genus-wide view of the biological diversity of the aspergilli and in many, but not all, cases linked genome differences to phenotype. Insights gained could be exploited for biotechnological and medical applications of fungi.
ESTHER : de Vries_2017_Genome.Biol_18_28
PubMedSearch : de Vries_2017_Genome.Biol_18_28
PubMedID: 28196534
Gene_locus related to this paper: asptu-a0a1l9nhd0 , aspve-a0a1l9pxx8 , aspve-a0a1l9q4m3 , aspwe-a0a1l9s133 , 9euro-a0a1l9t3v9 , aspwe-a0a1l9rcx6 , aspna-g3y5a6 , aspgl-a0a1l9v4d3 , 9euro-a0a1l9sa36 , aspsb-a0a319eji6 , aspve-a0a1l9px96 , 9euro-a0a1l9tay1 , aspgl-a0a1l9vbc0 , aspc5-a0a1r3rh65 , 9euro-a0a2v5i956 , aspwe-a0a1l9rpp6 , aspna-g3xpw9 , aspve-a0a1l9plv1 , 9euro-a0a1l9tk47 , aspve-a0a1l9pde9 , aspve-a0a1l9pz72 , aspwe-a0a1l9rde6 , 9euro-a0a1l9tdb5 , aspkw-g7xq95 , aspbc-a0a1l9u6h4 , aspbc-a0a1l9u2l4 , asptc-a0a1l9mx83 , aspgl-a0a1l9ve90 , aspve-a0a1l9pvz9 , 9euro-a0a1l9tdh3 , aspc5-a0a1r3rmn9 , aspwe-a0a1l9rlq2 , asptc-a0a1l9nby7 , aspng-a0a100i8t9 , aspc5-a0a1r3rem6 , aspbc-a0a1l9uy89 , aspa1-anee , aspa1-aneh , aspa1-acrc , aspbc-alba , aspa1-acui

Title : Characterization of four endophytic fungi as potential consolidated bioprocessing hosts for conversion of lignocellulose into advanced biofuels - Wu_2017_Appl.Microbiol.Biotechnol_101_2603
Author(s) : Wu W , Davis RW , Tran-Gyamfi MB , Kuo A , LaButti K , Mihaltcheva S , Hundley H , Chovatia M , Lindquist E , Barry K , Grigoriev IV , Henrissat B , Gladden JM
Ref : Applied Microbiology & Biotechnology , 101 :2603 , 2017
Abstract : Recently, several endophytic fungi have been demonstrated to produce volatile organic compounds (VOCs) with properties similar to fossil fuels, called "mycodiesel," while growing on lignocellulosic plant and agricultural residues. The fact that endophytes are plant symbionts suggests that some may be able to produce lignocellulolytic enzymes, making them capable of both deconstructing lignocellulose and converting it into mycodiesel, two properties that indicate that these strains may be useful consolidated bioprocessing (CBP) hosts for the biofuel production. In this study, four endophytes Hypoxylon sp. CI4A, Hypoxylon sp. EC38, Hypoxylon sp. CO27, and Daldinia eschscholzii EC12 were selected and evaluated for their CBP potential. Analysis of their genomes indicates that these endophytes have a rich reservoir of biomass-deconstructing carbohydrate-active enzymes (CAZys), which includes enzymes active on both polysaccharides and lignin, as well as terpene synthases (TPSs), enzymes that may produce fuel-like molecules, suggesting that they do indeed have CBP potential. GC-MS analyses of their VOCs when grown on four representative lignocellulosic feedstocks revealed that these endophytes produce a wide spectrum of hydrocarbons, the majority of which are monoterpenes and sesquiterpenes, including some known biofuel candidates. Analysis of their cellulase activity when grown under the same conditions revealed that these endophytes actively produce endoglucanases, exoglucanases, and beta-glucosidases. The richness of CAZymes as well as terpene synthases identified in these four endophytic fungi suggests that they are great candidates to pursue for development into platform CBP organisms.
ESTHER : Wu_2017_Appl.Microbiol.Biotechnol_101_2603
PubMedSearch : Wu_2017_Appl.Microbiol.Biotechnol_101_2603
PubMedID: 28078400
Gene_locus related to this paper: 9pezi-a0a1y2u1s8 , 9pezi-a0a1y2x077 , 9pezi-a0a1y2vv92 , 9pezi-a0a1y2txs8 , 9pezi-a0a1y2wzb7 , 9pezi-a0a1y2ufj7 , 9pezi-a0a1y2vvc9 , 9pezi-a0a1y2w3w4

Title : Genome sequence of the plant growth promoting endophytic yeast Rhodotorula graminis WP1 -
Author(s) : Firrincieli A , Otillar R , Salamov A , Schmutz J , Khan Z , Redman RS , Fleck ND , Lindquist E , Grigoriev IV , Doty SL
Ref : Front Microbiol , 6 :978 , 2015
PubMedID: 26441909
Gene_locus related to this paper: rhogw-a0a0p9evi9

Title : The genome of Eucalyptus grandis - Myburg_2014_Nature_510_356
Author(s) : Myburg AA , Grattapaglia D , Tuskan GA , Hellsten U , Hayes RD , Grimwood J , Jenkins J , Lindquist E , Tice H , Bauer D , Goodstein DM , Dubchak I , Poliakov A , Mizrachi E , Kullan AR , Hussey SG , Pinard D , van der Merwe K , Singh P , van Jaarsveld I , Silva-Junior OB , Togawa RC , Pappas MR , Faria DA , Sansaloni CP , Petroli CD , Yang X , Ranjan P , Tschaplinski TJ , Ye CY , Li T , Sterck L , Vanneste K , Murat F , Soler M , Clemente HS , Saidi N , Cassan-Wang H , Dunand C , Hefer CA , Bornberg-Bauer E , Kersting AR , Vining K , Amarasinghe V , Ranik M , Naithani S , Elser J , Boyd AE , Liston A , Spatafora JW , Dharmwardhana P , Raja R , Sullivan C , Romanel E , Alves-Ferreira M , Kulheim C , Foley W , Carocha V , Paiva J , Kudrna D , Brommonschenkel SH , Pasquali G , Byrne M , Rigault P , Tibbits J , Spokevicius A , Jones RC , Steane DA , Vaillancourt RE , Potts BM , Joubert F , Barry K , Pappas GJ , Strauss SH , Jaiswal P , Grima-Pettenati J , Salse J , Van de Peer Y , Rokhsar DS , Schmutz J
Ref : Nature , 510 :356 , 2014
Abstract : Eucalypts are the world's most widely planted hardwood trees. Their outstanding diversity, adaptability and growth have made them a global renewable resource of fibre and energy. We sequenced and assembled >94% of the 640-megabase genome of Eucalyptus grandis. Of 36,376 predicted protein-coding genes, 34% occur in tandem duplications, the largest proportion thus far in plant genomes. Eucalyptus also shows the highest diversity of genes for specialized metabolites such as terpenes that act as chemical defence and provide unique pharmaceutical oils. Genome sequencing of the E. grandis sister species E. globulus and a set of inbred E. grandis tree genomes reveals dynamic genome evolution and hotspots of inbreeding depression. The E. grandis genome is the first reference for the eudicot order Myrtales and is placed here sister to the eurosids. This resource expands our understanding of the unique biology of large woody perennials and provides a powerful tool to accelerate comparative biology, breeding and biotechnology.
ESTHER : Myburg_2014_Nature_510_356
PubMedSearch : Myburg_2014_Nature_510_356
PubMedID: 24919147
Gene_locus related to this paper: eucgr-a0a059d0n8 , eucgr-a0a059cm68 , eucgr-a0a059d783 , eucgr-a0a059af93 , eucgr-a0a059awi0 , eucgr-a0a059awt4 , eucgr-a0a059ar83 , eucgr-a0a059ayw5 , eucgr-a0a059az75 , eucgr-a0a059azj1 , eucgr-a0a059azq5 , eucgr-a0a059bkm2 , eucgr-a0a059bl38 , eucgr-a0a059a7m2 , eucgr-a0a059a6p6 , eucgr-a0a059a6p1 , eucgr-a0a059a5e9 , eucgr-a0a059cpq4 , eucgr-a0a059b8v5

Title : Analysis of the Phlebiopsis gigantea genome, transcriptome and secretome provides insight into its pioneer colonization strategies of wood - Hori_2014_PLoS.Genet_10_e1004759
Author(s) : Hori C , Ishida T , Igarashi K , Samejima M , Suzuki H , Master E , Ferreira P , Ruiz-Duenas FJ , Held B , Canessa P , Larrondo LF , Schmoll M , Druzhinina IS , Kubicek CP , Gaskell JA , Kersten P , St John F , Glasner J , Sabat G , Splinter BonDurant S , Syed K , Yadav J , Mgbeahuruike AC , Kovalchuk A , Asiegbu FO , Lackner G , Hoffmeister D , Rencoret J , Gutierrez A , Sun H , Lindquist E , Barry K , Riley R , Grigoriev IV , Henrissat B , Kues U , Berka RM , Martinez AT , Covert SF , Blanchette RA , Cullen D
Ref : PLoS Genet , 10 :e1004759 , 2014
Abstract : Collectively classified as white-rot fungi, certain basidiomycetes efficiently degrade the major structural polymers of wood cell walls. A small subset of these Agaricomycetes, exemplified by Phlebiopsis gigantea, is capable of colonizing freshly exposed conifer sapwood despite its high content of extractives, which retards the establishment of other fungal species. The mechanism(s) by which P. gigantea tolerates and metabolizes resinous compounds have not been explored. Here, we report the annotated P. gigantea genome and compare profiles of its transcriptome and secretome when cultured on fresh-cut versus solvent-extracted loblolly pine wood. The P. gigantea genome contains a conventional repertoire of hydrolase genes involved in cellulose/hemicellulose degradation, whose patterns of expression were relatively unperturbed by the absence of extractives. The expression of genes typically ascribed to lignin degradation was also largely unaffected. In contrast, genes likely involved in the transformation and detoxification of wood extractives were highly induced in its presence. Their products included an ABC transporter, lipases, cytochrome P450s, glutathione S-transferase and aldehyde dehydrogenase. Other regulated genes of unknown function and several constitutively expressed genes are also likely involved in P. gigantea's extractives metabolism. These results contribute to our fundamental understanding of pioneer colonization of conifer wood and provide insight into the diverse chemistries employed by fungi in carbon cycling processes.
ESTHER : Hori_2014_PLoS.Genet_10_e1004759
PubMedSearch : Hori_2014_PLoS.Genet_10_e1004759
PubMedID: 25474575
Gene_locus related to this paper: phlgi-a0a0c3nds0 , phlgi-a0a0c3niq6 , phlgi-a0a0c3pc91 , phlgi-a0a0c3pv58 , phlgi-a0a0c3rra0 , phlgi-a0a0c3rvc4 , phlgi-a0a0c3rvu0 , phlgi-a0a0c3s394 , phlgi-a0a0c3s606 , phlgi-a0a0c3s673 , phlgi-a0a0c3s8d3 , phlgi-a0a0c3sce4 , phlgi-a0a0c3sdt8

Title : Comparative genome structure, secondary metabolite, and effector coding capacity across Cochliobolus pathogens - Condon_2013_PLoS.Genet_9_e1003233
Author(s) : Condon BJ , Leng Y , Wu D , Bushley KE , Ohm RA , Otillar R , Martin J , Schackwitz W , Grimwood J , MohdZainudin N , Xue C , Wang R , Manning VA , Dhillon B , Tu ZJ , Steffenson BJ , Salamov A , Sun H , Lowry S , LaButti K , Han J , Copeland A , Lindquist E , Barry K , Schmutz J , Baker SE , Ciuffetti LM , Grigoriev IV , Zhong S , Turgeon BG
Ref : PLoS Genet , 9 :e1003233 , 2013
Abstract : The genomes of five Cochliobolus heterostrophus strains, two Cochliobolus sativus strains, three additional Cochliobolus species (Cochliobolus victoriae, Cochliobolus carbonum, Cochliobolus miyabeanus), and closely related Setosphaeria turcica were sequenced at the Joint Genome Institute (JGI). The datasets were used to identify SNPs between strains and species, unique genomic regions, core secondary metabolism genes, and small secreted protein (SSP) candidate effector encoding genes with a view towards pinpointing structural elements and gene content associated with specificity of these closely related fungi to different cereal hosts. Whole-genome alignment shows that three to five percent of each genome differs between strains of the same species, while a quarter of each genome differs between species. On average, SNP counts among field isolates of the same C. heterostrophus species are more than 25x higher than those between inbred lines and 50x lower than SNPs between Cochliobolus species. The suites of nonribosomal peptide synthetase (NRPS), polyketide synthase (PKS), and SSP-encoding genes are astoundingly diverse among species but remarkably conserved among isolates of the same species, whether inbred or field strains, except for defining examples that map to unique genomic regions. Functional analysis of several strain-unique PKSs and NRPSs reveal a strong correlation with a role in virulence.
ESTHER : Condon_2013_PLoS.Genet_9_e1003233
PubMedSearch : Condon_2013_PLoS.Genet_9_e1003233
PubMedID: 23357949
Gene_locus related to this paper: cocsn-m2rnc6 , coch5-m2tnl8 , coch4-n4xap8 , sett2-r0j560 , cocsn-m2thl9 , coch5-m2v1s2 , coch4-n4xzy1 , cocsn-m2sqr3 , cocsn-m2rnk8 , coch4-n4xdv7 , coch5-m2uds0 , coch5-m2um94 , sett2-r0i8c5 , coch4-n4wlc8 , coch4-n4x9p3 , cocsn-m2rh47 , cocsn-m2qz08 , sett2-r0jqq6 , sett2-r0imb6 , coch4-n4x7u3 , cocsn-m2rv02 , cocsn-m2sy95 , coch5-m2ubd5 , cocsn-m2t3d2 , sett2-r0kl84 , sett2-r0jts7 , coch4-n4x2h3 , sett2-r0jxt9 , coch4-n4x7r9 , cocsn-m2sh75 , cocsn-m2t5z2 , coch5-m2ucf6 , sett2-r0k664 , cocsn-m2t3q1 , sett2-r0k4b4 , cocsn-m2t4i1 , coch5-m2th93 , cocsn-m2svm8 , cocsn-m2s6q4 , cocsn-m2s5h5 , coch4-n4xf94 , sett2-r0kdl8 , cocsn-m2qvi9 , sett2-r0kfg6 , cocsn-m2szq4 , sett2-r0j437 , coch4-n4x7j4 , coch5-m2twk3 , coch5-m2usf2 , sett2-r0kjt7 , sett2-r0k7y2 , cocsn-m2th03 , sett2-r0iy92 , sett2-r0kbr9 , sett2-r0k997 , coch5-m2sik6 , sett2-r0jzj5 , cocsn-m2r0j6 , coch4-n4x6a4 , cocsn-m2s7a5 , cocsn-m2sv79 , sett2-r0knx4 , sett2-r0ksh8 , sett2-r0ip86 , cocmi-w6yyy3 , cocsn-m2sqe4 , coch4-n4xzc8 , cocvi-w7eyp1 , cocmi-w6zf65 , cocvi-w7er28 , cocca-w6yw25 , cocvi-w7e2g6 , cocmi-w6z7k5 , cocca-w6ys73 , cocca-w6ydq2 , cocca-w6y7i5 , cocmi-w6yyr0 , cocca-w6yh47 , cocmi-w6zju4 , cocca-w6ynq5 , cocmi-w6zm44 , cocca-w6xx85 , cocmi-w6z011 , cocca-w6yre4 , cocmi-w6z9l3 , cocca-w6yfp7 , cocmi-w6zlc2 , cocca-w6yar2 , cocmi-w6yjr7 , cocca-w6yhs1 , cocca-w6xux8 , cocmi-w6z9s8 , cocca-w6yq27 , cocmi-w6zqk9 , cocca-w6xq19 , cocca-w6y1r6 , cocca-w6ygj2 , cocmi-w6zgn4 , cocca-w6ybh2 , cocmi-w6z710 , cocca-w6yk86 , cocmi-w6zjz2 , cocmi-w6z7f2 , cocca-w6xn57 , cocca-w6ybq4 , cocmi-w6yxn5 , cocmi-w6zf08 , cocsn-m2rtg8 , cocmi-w6zuj7 , cocca-w6xtb2 , cocca-w6yk97 , coch5-m2t2x3 , cocmi-w6z646 , cocsn-m2sze4 , sett2-r0kjg6 , cocmi-w6yrn5 , sett2-r0k5q0 , cocvi-w7ezb7 , sett2-r0jtm1 , cocmi-w6ywa1 , cocsn-m2t3e8 , coch5-m2ulw5 , coch5-m2urw9 , sett2-r0knn5 , cocmi-w6ysb2 , cocvi-w7eag7 , cocca-w6y1v2 , sett2-r0i9k2 , coch5-m2uul8 , cocsn-m2sl21

Title : Reference genome sequence of the model plant Setaria - Bennetzen_2012_Nat.Biotechnol_30_555
Author(s) : Bennetzen JL , Schmutz J , Wang H , Percifield R , Hawkins J , Pontaroli AC , Estep M , Feng L , Vaughn JN , Grimwood J , Jenkins J , Barry K , Lindquist E , Hellsten U , Deshpande S , Wang X , Wu X , Mitros T , Triplett J , Yang X , Ye CY , Mauro-Herrera M , Wang L , Li P , Sharma M , Sharma R , Ronald PC , Panaud O , Kellogg EA , Brutnell TP , Doust AN , Tuskan GA , Rokhsar D , Devos KM
Ref : Nat Biotechnol , 30 :555 , 2012
Abstract : We generated a high-quality reference genome sequence for foxtail millet (Setaria italica). The approximately 400-Mb assembly covers approximately 80% of the genome and >95% of the gene space. The assembly was anchored to a 992-locus genetic map and was annotated by comparison with >1.3 million expressed sequence tag reads. We produced more than 580 million RNA-Seq reads to facilitate expression analyses. We also sequenced Setaria viridis, the ancestral wild relative of S. italica, and identified regions of differential single-nucleotide polymorphism density, distribution of transposable elements, small RNA content, chromosomal rearrangement and segregation distortion. The genus Setaria includes natural and cultivated species that demonstrate a wide capacity for adaptation. The genetic basis of this adaptation was investigated by comparing five sequenced grass genomes. We also used the diploid Setaria genome to evaluate the ongoing genome assembly of a related polyploid, switchgrass (Panicum virgatum).
ESTHER : Bennetzen_2012_Nat.Biotechnol_30_555
PubMedSearch : Bennetzen_2012_Nat.Biotechnol_30_555
PubMedID: 22580951
Gene_locus related to this paper: setit-k3xwe0 , setit-k3xfs7 , setit-k3yh36 , setit-k3zes3 , setit-k3zlj8 , setvi-a0a4u6wd58 , setit-a0a368qif6 , setit-a0a368sru6 , setit-a0a368q9x4 , setit-k3zri0 , setit-k3ysv0 , setit-k3xj49 , setit-k4ac30

Title : Algal genomes reveal evolutionary mosaicism and the fate of nucleomorphs - Curtis_2012_Nature_492_59
Author(s) : Curtis BA , Tanifuji G , Burki F , Gruber A , Irimia M , Maruyama S , Arias MC , Ball SG , Gile GH , Hirakawa Y , Hopkins JF , Kuo A , Rensing SA , Schmutz J , Symeonidi A , Elias M , Eveleigh RJ , Herman EK , Klute MJ , Nakayama T , Obornik M , Reyes-Prieto A , Armbrust EV , Aves SJ , Beiko RG , Coutinho P , Dacks JB , Durnford DG , Fast NM , Green BR , Grisdale CJ , Hempel F , Henrissat B , Hoppner MP , Ishida K , Kim E , Koreny L , Kroth PG , Liu Y , Malik SB , Maier UG , McRose D , Mock T , Neilson JA , Onodera NT , Poole AM , Pritham EJ , Richards TA , Rocap G , Roy SW , Sarai C , Schaack S , Shirato S , Slamovits CH , Spencer DF , Suzuki S , Worden AZ , Zauner S , Barry K , Bell C , Bharti AK , Crow JA , Grimwood J , Kramer R , Lindquist E , Lucas S , Salamov A , McFadden GI , Lane CE , Keeling PJ , Gray MW , Grigoriev IV , Archibald JM
Ref : Nature , 492 :59 , 2012
Abstract : Cryptophyte and chlorarachniophyte algae are transitional forms in the widespread secondary endosymbiotic acquisition of photosynthesis by engulfment of eukaryotic algae. Unlike most secondary plastid-bearing algae, miniaturized versions of the endosymbiont nuclei (nucleomorphs) persist in cryptophytes and chlorarachniophytes. To determine why, and to address other fundamental questions about eukaryote-eukaryote endosymbiosis, we sequenced the nuclear genomes of the cryptophyte Guillardia theta and the chlorarachniophyte Bigelowiella natans. Both genomes have >21,000 protein genes and are intron rich, and B. natans exhibits unprecedented alternative splicing for a single-celled organism. Phylogenomic analyses and subcellular targeting predictions reveal extensive genetic and biochemical mosaicism, with both host- and endosymbiont-derived genes servicing the mitochondrion, the host cell cytosol, the plastid and the remnant endosymbiont cytosol of both algae. Mitochondrion-to-nucleus gene transfer still occurs in both organisms but plastid-to-nucleus and nucleomorph-to-nucleus transfers do not, which explains why a small residue of essential genes remains locked in each nucleomorph.
ESTHER : Curtis_2012_Nature_492_59
PubMedSearch : Curtis_2012_Nature_492_59
PubMedID: 23201678
Gene_locus related to this paper: guith-l1i9i5 , guith-l1k167 , guitc-l1jmn9

Title : The genome of the xerotolerant mold Wallemia sebi reveals adaptations to osmotic stress and suggests cryptic sexual reproduction - Padamsee_2012_Fungal.Genet.Biol_49_217
Author(s) : Padamsee M , Kumar TK , Riley R , Binder M , Boyd A , Calvo AM , Furukawa K , Hesse C , Hohmann S , James TY , LaButti K , Lapidus A , Lindquist E , Lucas S , Miller K , Shantappa S , Grigoriev IV , Hibbett DS , McLaughlin DJ , Spatafora JW , Aime MC
Ref : Fungal Genet Biol , 49 :217 , 2012
Abstract : Wallemia (Wallemiales, Wallemiomycetes) is a genus of xerophilic Fungi of uncertain phylogenetic position within Basidiomycota. Most commonly found as food contaminants, species of Wallemia have also been isolated from hypersaline environments. The ability to tolerate environments with reduced water activity is rare in Basidiomycota. We sequenced the genome of W. sebi in order to understand its adaptations for surviving in osmotically challenging environments, and we performed phylogenomic and ultrastructural analyses to address its systematic placement and reproductive biology. W. sebi has a compact genome (9.8 Mb), with few repeats and the largest fraction of genes with functional domains compared with other Basidiomycota. We applied several approaches to searching for osmotic stress-related proteins. In silico analyses identified 93 putative osmotic stress proteins; homology searches showed the HOG (High Osmolarity Glycerol) pathway to be mostly conserved. Despite the seemingly reduced genome, several gene family expansions and a high number of transporters (549) were found that also provide clues to the ability of W. sebi to colonize harsh environments. Phylogenetic analyses of a 71-protein dataset support the position of Wallemia as the earliest diverging lineage of Agaricomycotina, which is confirmed by septal pore ultrastructure that shows the septal pore apparatus as a variant of the Tremella-type. Mating type gene homologs were identified although we found no evidence of meiosis during conidiogenesis, suggesting there may be aspects of the life cycle of W. sebi that remain cryptic.
ESTHER : Padamsee_2012_Fungal.Genet.Biol_49_217
PubMedSearch : Padamsee_2012_Fungal.Genet.Biol_49_217
PubMedID: 22326418
Gene_locus related to this paper: walsc-i4y6w1 , walmc-i4y5m3

Title : Comparative genomics of the white-rot fungi, Phanerochaete carnosa and P. chrysosporium, to elucidate the genetic basis of the distinct wood types they colonize - Suzuki_2012_BMC.Genomics_13_444
Author(s) : Suzuki H , MacDonald J , Syed K , Salamov A , Hori C , Aerts A , Henrissat B , Wiebenga A , vanKuyk PA , Barry K , Lindquist E , LaButti K , Lapidus A , Lucas S , Coutinho P , Gong Y , Samejima M , Mahadevan R , Abou-Zaid M , de Vries RP , Igarashi K , Yadav JS , Grigoriev IV , Master ER
Ref : BMC Genomics , 13 :444 , 2012
Abstract : BACKGROUND: Softwood is the predominant form of land plant biomass in the Northern hemisphere, and is among the most recalcitrant biomass resources to bioprocess technologies. The white rot fungus, Phanerochaete carnosa, has been isolated almost exclusively from softwoods, while most other known white-rot species, including Phanerochaete chrysosporium, were mainly isolated from hardwoods. Accordingly, it is anticipated that P. carnosa encodes a distinct set of enzymes and proteins that promote softwood decomposition. To elucidate the genetic basis of softwood bioconversion by a white-rot fungus, the present study reports the P. carnosa genome sequence and its comparative analysis with the previously reported P. chrysosporium genome.
RESULTS: P. carnosa encodes a complete set of lignocellulose-active enzymes. Comparative genomic analysis revealed that P. carnosa is enriched with genes encoding manganese peroxidase, and that the most divergent glycoside hydrolase families were predicted to encode hemicellulases and glycoprotein degrading enzymes. Most remarkably, P. carnosa possesses one of the largest P450 contingents (266 P450s) among the sequenced and annotated wood-rotting basidiomycetes, nearly double that of P. chrysosporium. Along with metabolic pathway modeling, comparative growth studies on model compounds and chemical analyses of decomposed wood components showed greater tolerance of P. carnosa to various substrates including coniferous heartwood.
CONCLUSIONS: The P. carnosa genome is enriched with genes that encode P450 monooxygenases that can participate in extractives degradation, and manganese peroxidases involved in lignin degradation. The significant expansion of P450s in P. carnosa, along with differences in carbohydrate- and lignin-degrading enzymes, could be correlated to the utilization of heartwood and sapwood preparations from both coniferous and hardwood species.
ESTHER : Suzuki_2012_BMC.Genomics_13_444
PubMedSearch : Suzuki_2012_BMC.Genomics_13_444
PubMedID: 22937793
Gene_locus related to this paper: phacs-k5whx2 , phacs-k5v2s8 , phacs-k5v5r2 , phacs-k5vyk5 , phacs-k5vzf8 , phacs-k5wbu9 , phacs-k5wc10 , phacs-k5wpw0 , phacs-k5wzn6 , phacs-k5x1t8 , phacs-k5x5g6 , phacs-k5x5p4

Title : The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes - Floudas_2012_Science_336_1715
Author(s) : Floudas D , Binder M , Riley R , Barry K , Blanchette RA , Henrissat B , Martinez AT , Otillar R , Spatafora JW , Yadav JS , Aerts A , Benoit I , Boyd A , Carlson A , Copeland A , Coutinho PM , de Vries RP , Ferreira P , Findley K , Foster B , Gaskell J , Glotzer D , Gorecki P , Heitman J , Hesse C , Hori C , Igarashi K , Jurgens JA , Kallen N , Kersten P , Kohler A , Kues U , Kumar TK , Kuo A , LaButti K , Larrondo LF , Lindquist E , Ling A , Lombard V , Lucas S , Lundell T , Martin R , McLaughlin DJ , Morgenstern I , Morin E , Murat C , Nagy LG , Nolan M , Ohm RA , Patyshakuliyeva A , Rokas A , Ruiz-Duenas FJ , Sabat G , Salamov A , Samejima M , Schmutz J , Slot JC , St John F , Stenlid J , Sun H , Sun S , Syed K , Tsang A , Wiebenga A , Young D , Pisabarro A , Eastwood DC , Martin F , Cullen D , Grigoriev IV , Hibbett DS
Ref : Science , 336 :1715 , 2012
Abstract : Wood is a major pool of organic carbon that is highly resistant to decay, owing largely to the presence of lignin. The only organisms capable of substantial lignin decay are white rot fungi in the Agaricomycetes, which also contains non-lignin-degrading brown rot and ectomycorrhizal species. Comparative analyses of 31 fungal genomes (12 generated for this study) suggest that lignin-degrading peroxidases expanded in the lineage leading to the ancestor of the Agaricomycetes, which is reconstructed as a white rot species, and then contracted in parallel lineages leading to brown rot and mycorrhizal species. Molecular clock analyses suggest that the origin of lignin degradation might have coincided with the sharp decrease in the rate of organic carbon burial around the end of the Carboniferous period.
ESTHER : Floudas_2012_Science_336_1715
PubMedSearch : Floudas_2012_Science_336_1715
PubMedID: 22745431
Gene_locus related to this paper: aurde-j0d098 , aurde-j0dc31 , glota-s7rlc1 , fompi-s8f7s4 , dacsp-m5fpg2 , dicsq-r7sm16 , dacsp-m5g7q5 , dacsp-m5fr12 , glota-s7q5w3 , fompi-s8f826.1 , fompi-s8f826.2 , dicsq-r7sy09 , glota-s7rt87 , dicsq-r7t032 , glota-s7rym7 , fompi-s8fiv2 , dacsp-m5gda3.2 , dicsq-r7swi6 , dacsp-m5frf2 , fompi-s8ebb6 , dicsq-r7sln3 , dicsq-r7sya6 , dacsp-m5g7g1 , dicsq-r7syx7 , dicsq-r7sx57 , dacsp-m5fps7 , glota-s7pwi7 , dicsq-r7swj6 , fompi-s8ejq6 , dicsq-r7spc3 , glota-s7q258 , dacsp-m5ft65 , glota-s7q3m7 , fompi-s8dkc7 , glota-s7q1z1 , fompi-s8eqi2 , glota-s7q1z8 , fompi-s8du50 , dacsp-m5gg33 , dacsp-m5g3a7 , fompi-s8ecd7 , fompi-s8dps1 , dacsp-m5fwr0 , dicsq-r7sub7 , glota-s7q8k9 , fompi-s8ffc3 , dacsp-m5g2f9 , fompi-s8ecc2 , dacsp-m5g868 , fompi-s8f890 , dicsq-r7t1a8 , fompi-s8ebx4 , fompi-s8eb97 , glota-s7q222 , glota-s7puf0 , fompi-s8f6v9 , dacsp-m5g0z2 , dacsp-m5gdh9 , fompi-s8fb37 , dacsp-m5fy91 , glota-s7q5v6 , fompi-s8fl44 , dicsq-r7stv9 , dicsq-r7szk3 , fompi-s8epq9 , glota-s7rh56 , dacsp-m5gbt1 , punst-r7s3x9 , punst-r7s0t5 , glota-s7q312 , glota-s7rhh6 , dicsq-r7t117 , dicsq-r7slz3

Title : The genomes of the fungal plant pathogens Cladosporium fulvum and Dothistroma septosporum reveal adaptation to different hosts and lifestyles but also signatures of common ancestry - de Wit_2012_PLoS.Genet_8_E1003088
Author(s) : de Wit PJ , van der Burgt A , Okmen B , Stergiopoulos I , Abd-Elsalam KA , Aerts AL , Bahkali AH , Beenen HG , Chettri P , Cox MP , Datema E , de Vries RP , Dhillon B , Ganley AR , Griffiths SA , Guo Y , Hamelin RC , Henrissat B , Kabir MS , Jashni MK , Kema G , Klaubauf S , Lapidus A , Levasseur A , Lindquist E , Mehrabi R , Ohm RA , Owen TJ , Salamov A , Schwelm A , Schijlen E , Sun H , van den Burg HA , van Ham RC , Zhang S , Goodwin SB , Grigoriev IV , Collemare J , Bradshaw RE
Ref : PLoS Genet , 8 :e1003088 , 2012
Abstract : We sequenced and compared the genomes of the Dothideomycete fungal plant pathogens Cladosporium fulvum (Cfu) (syn. Passalora fulva) and Dothistroma septosporum (Dse) that are closely related phylogenetically, but have different lifestyles and hosts. Although both fungi grow extracellularly in close contact with host mesophyll cells, Cfu is a biotroph infecting tomato, while Dse is a hemibiotroph infecting pine. The genomes of these fungi have a similar set of genes (70% of gene content in both genomes are homologs), but differ significantly in size (Cfu >61.1-Mb; Dse 31.2-Mb), which is mainly due to the difference in repeat content (47.2% in Cfu versus 3.2% in Dse). Recent adaptation to different lifestyles and hosts is suggested by diverged sets of genes. Cfu contains an alpha-tomatinase gene that we predict might be required for detoxification of tomatine, while this gene is absent in Dse. Many genes encoding secreted proteins are unique to each species and the repeat-rich areas in Cfu are enriched for these species-specific genes. In contrast, conserved genes suggest common host ancestry. Homologs of Cfu effector genes, including Ecp2 and Avr4, are present in Dse and induce a Cf-Ecp2- and Cf-4-mediated hypersensitive response, respectively. Strikingly, genes involved in production of the toxin dothistromin, a likely virulence factor for Dse, are conserved in Cfu, but their expression differs markedly with essentially no expression by Cfu in planta. Likewise, Cfu has a carbohydrate-degrading enzyme catalog that is more similar to that of necrotrophs or hemibiotrophs and a larger pectinolytic gene arsenal than Dse, but many of these genes are not expressed in planta or are pseudogenized. Overall, comparison of their genomes suggests that these closely related plant pathogens had a common ancestral host but since adapted to different hosts and lifestyles by a combination of differentiated gene content, pseudogenization, and gene regulation.
ESTHER : de Wit_2012_PLoS.Genet_8_E1003088
PubMedSearch : de Wit_2012_PLoS.Genet_8_E1003088
PubMedID: 23209441
Gene_locus related to this paper: mycpj-q30dw8 , mycp1-n1pnd6 , mycp1-n1per0 , mycp1-n1pg49 , mycp1-n1pwj1 , mycp1-n1pcl8 , mycp1-m2y2b1 , mycp1-n1pwu7 , mycp1-n1ppa8 , mycp1-m2yk59 , mycp1-n1pps5 , mycp1-n1pw13 , mycp1-n1pe19 , mycp1-m2xhl1 , mycp1-n1pnh6 , mycp1-n1psn5 , mycp1-n1puh9 , mycp1-n1phf7 , mycp1-m2y2h4 , mycp1-n1q523 , dotsn-n1q1b1 , dotsn-n1q415 , dotsn-est1

Title : The genome of the polar eukaryotic microalga Coccomyxa subellipsoidea reveals traits of cold adaptation - Blanc_2012_Genome.Biol_13_R39
Author(s) : Blanc G , Agarkova I , Grimwood J , Kuo A , Brueggeman A , Dunigan DD , Gurnon J , Ladunga I , Lindquist E , Lucas S , Pangilinan J , Proschold T , Salamov A , Schmutz J , Weeks D , Yamada T , Lomsadze A , Borodovsky M , Claverie JM , Grigoriev IV , Van Etten JL
Ref : Genome Biol , 13 :R39 , 2012
Abstract : BACKGROUND: Little is known about the mechanisms of adaptation of life to the extreme environmental conditions encountered in polar regions. Here we present the genome sequence of a unicellular green alga from the division chlorophyta, Coccomyxa subellipsoidea C-169, which we will hereafter refer to as C-169. This is the first eukaryotic microorganism from a polar environment to have its genome sequenced.
RESULTS: The 48.8 Mb genome contained in 20 chromosomes exhibits significant synteny conservation with the chromosomes of its relatives Chlorella variabilis and Chlamydomonas reinhardtii. The order of the genes is highly reshuffled within synteny blocks, suggesting that intra-chromosomal rearrangements were more prevalent than inter-chromosomal rearrangements. Remarkably, Zepp retrotransposons occur in clusters of nested elements with strictly one cluster per chromosome probably residing at the centromere. Several protein families overrepresented in C. subellipsoidae include proteins involved in lipid metabolism, transporters, cellulose synthases and short alcohol dehydrogenases. Conversely, C-169 lacks proteins that exist in all other sequenced chlorophytes, including components of the glycosyl phosphatidyl inositol anchoring system, pyruvate phosphate dikinase and the photosystem 1 reaction center subunit N (PsaN).
CONCLUSIONS: We suggest that some of these gene losses and gains could have contributed to adaptation to low temperatures. Comparison of these genomic features with the adaptive strategies of psychrophilic microbes suggests that prokaryotes and eukaryotes followed comparable evolutionary routes to adapt to cold environments.
ESTHER : Blanc_2012_Genome.Biol_13_R39
PubMedSearch : Blanc_2012_Genome.Biol_13_R39
PubMedID: 22630137
Gene_locus related to this paper: 9chlo-i0z4k0 , 9chlo-i0ylt0 , cocsc-i0ytb9 , cocsc-i0yin5

Title : Insight into trade-off between wood decay and parasitism from the genome of a fungal forest pathogen - Olson_2012_New.Phytol_194_1001
Author(s) : Olson A , Aerts A , Asiegbu F , Belbahri L , Bouzid O , Broberg A , Canback B , Coutinho PM , Cullen D , Dalman K , Deflorio G , van Diepen LT , Dunand C , Duplessis S , Durling M , Gonthier P , Grimwood J , Fossdal CG , Hansson D , Henrissat B , Hietala A , Himmelstrand K , Hoffmeister D , Hogberg N , James TY , Karlsson M , Kohler A , Kues U , Lee YH , Lin YC , Lind M , Lindquist E , Lombard V , Lucas S , Lunden K , Morin E , Murat C , Park J , Raffaello T , Rouze P , Salamov A , Schmutz J , Solheim H , Stahlberg J , Velez H , de Vries RP , Wiebenga A , Woodward S , Yakovlev I , Garbelotto M , Martin F , Grigoriev IV , Stenlid J
Ref : New Phytol , 194 :1001 , 2012
Abstract : Parasitism and saprotrophic wood decay are two fungal strategies fundamental for succession and nutrient cycling in forest ecosystems. An opportunity to assess the trade-off between these strategies is provided by the forest pathogen and wood decayer Heterobasidion annosum sensu lato. We report the annotated genome sequence and transcript profiling, as well as the quantitative trait loci mapping, of one member of the species complex: H. irregulare. Quantitative trait loci critical for pathogenicity, and rich in transposable elements, orphan and secreted genes, were identified. A wide range of cellulose-degrading enzymes are expressed during wood decay. By contrast, pathogenic interaction between H. irregulare and pine engages fewer carbohydrate-active enzymes, but involves an increase in pectinolytic enzymes, transcription modules for oxidative stress and secondary metabolite production. Our results show a trade-off in terms of constrained carbohydrate decomposition and membrane transport capacity during interaction with living hosts. Our findings establish that saprotrophic wood decay and necrotrophic parasitism involve two distinct, yet overlapping, processes.
ESTHER : Olson_2012_New.Phytol_194_1001
PubMedSearch : Olson_2012_New.Phytol_194_1001
PubMedID: 22463738
Gene_locus related to this paper: 9homo-w4jrb9 , 9homo-w4jsg4 , 9homo-w4kds7 , 9homo-w4jwl9 , 9homo-w4kjy2 , 9homo-w4jw43 , 9homo-w4ka20 , 9homo-w4k8t3 , 9homo-w4jz43 , 9homo-w4k8q2 , 9homo-w4k910 , 9homo-w4k6f5 , 9homo-w4k6j3 , 9homo-w4k8n2 , 9homo-w4jrf3 , 9homo-w4ke07 , 9homo-w4k3i8 , 9homo-w4jqh1 , 9agam-w4k203 , 9agam-w4jpy3 , 9agam-w4jn81 , 9agam-w4jmz2

Title : Finished genome of the fungal wheat pathogen Mycosphaerella graminicola reveals dispensome structure, chromosome plasticity, and stealth pathogenesis - Goodwin_2011_PLoS.Genet_7_e1002070
Author(s) : Goodwin SB , M'Barek S B , Dhillon B , Wittenberg AH , Crane CF , Hane JK , Foster AJ , Van der Lee TA , Grimwood J , Aerts A , Antoniw J , Bailey A , Bluhm B , Bowler J , Bristow J , van der Burgt A , Canto-Canche B , Churchill AC , Conde-Ferraez L , Cools HJ , Coutinho PM , Csukai M , Dehal P , De Wit P , Donzelli B , van de Geest HC , van Ham RC , Hammond-Kosack KE , Henrissat B , Kilian A , Kobayashi AK , Koopmann E , Kourmpetis Y , Kuzniar A , Lindquist E , Lombard V , Maliepaard C , Martins N , Mehrabi R , Nap JP , Ponomarenko A , Rudd JJ , Salamov A , Schmutz J , Schouten HJ , Shapiro H , Stergiopoulos I , Torriani SF , Tu H , de Vries RP , Waalwijk C , Ware SB , Wiebenga A , Zwiers LH , Oliver RP , Grigoriev IV , Kema GH
Ref : PLoS Genet , 7 :e1002070 , 2011
Abstract : The plant-pathogenic fungus Mycosphaerella graminicola (asexual stage: Septoria tritici) causes septoria tritici blotch, a disease that greatly reduces the yield and quality of wheat. This disease is economically important in most wheat-growing areas worldwide and threatens global food production. Control of the disease has been hampered by a limited understanding of the genetic and biochemical bases of pathogenicity, including mechanisms of infection and of resistance in the host. Unlike most other plant pathogens, M. graminicola has a long latent period during which it evades host defenses. Although this type of stealth pathogenicity occurs commonly in Mycosphaerella and other Dothideomycetes, the largest class of plant-pathogenic fungi, its genetic basis is not known. To address this problem, the genome of M. graminicola was sequenced completely. The finished genome contains 21 chromosomes, eight of which could be lost with no visible effect on the fungus and thus are dispensable. This eight-chromosome dispensome is dynamic in field and progeny isolates, is different from the core genome in gene and repeat content, and appears to have originated by ancient horizontal transfer from an unknown donor. Synteny plots of the M. graminicola chromosomes versus those of the only other sequenced Dothideomycete, Stagonospora nodorum, revealed conservation of gene content but not order or orientation, suggesting a high rate of intra-chromosomal rearrangement in one or both species. This observed "mesosynteny" is very different from synteny seen between other organisms. A surprising feature of the M. graminicola genome compared to other sequenced plant pathogens was that it contained very few genes for enzymes that break down plant cell walls, which was more similar to endophytes than to pathogens. The stealth pathogenesis of M. graminicola probably involves degradation of proteins rather than carbohydrates to evade host defenses during the biotrophic stage of infection and may have evolved from endophytic ancestors.
ESTHER : Goodwin_2011_PLoS.Genet_7_e1002070
PubMedSearch : Goodwin_2011_PLoS.Genet_7_e1002070
PubMedID: 21695235
Gene_locus related to this paper: zymti-f9wzw8 , zymti-f9x2y6 , zymti-f9x423 , zymti-f9x813 , zymti-f9xa54 , zymti-f9xb42 , zymti-f9xbu5 , zymti-f9xcr9 , zymti-f9xdr7 , zymti-f9xer1 , zymti-f9xez8 , zymti-f9xfz9 , zymti-f9xh29 , zymti-f9xhe7 , zymti-f9xhr4 , zymti-f9xk09 , zymti-f9xns5 , zymti-f9xiu1 , zymti-f9xng3 , zymti-f9x4f2 , zymti-f9x4s7 , zymti-f9xdm8 , zymti-f9wwy9 , zymti-f9xkf2 , zymti-f9xlt3 , zymti-f9x0i3 , zymti-f9wwa6 , zymti-f9wyk7 , zymti-f9x3z1 , zymti-f9xf16 , zymtr-a0a1x7rhi5 , zymti-f9xfj3 , zymti-pks1

Title : Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88 - Andersen_2011_Genome.Res_21_885
Author(s) : Andersen MR , Salazar MP , Schaap PJ , van de Vondervoort PJ , Culley D , Thykaer J , Frisvad JC , Nielsen KF , Albang R , Albermann K , Berka RM , Braus GH , Braus-Stromeyer SA , Corrochano LM , Dai Z , van Dijck PW , Hofmann G , Lasure LL , Magnuson JK , Menke H , Meijer M , Meijer SL , Nielsen JB , Nielsen ML , van Ooyen AJ , Pel HJ , Poulsen L , Samson RA , Stam H , Tsang A , van den Brink JM , Atkins A , Aerts A , Shapiro H , Pangilinan J , Salamov A , Lou Y , Lindquist E , Lucas S , Grimwood J , Grigoriev IV , Kubicek CP , Martinez D , van Peij NN , Roubos JA , Nielsen J , Baker SE
Ref : Genome Res , 21 :885 , 2011
Abstract : The filamentous fungus Aspergillus niger exhibits great diversity in its phenotype. It is found globally, both as marine and terrestrial strains, produces both organic acids and hydrolytic enzymes in high amounts, and some isolates exhibit pathogenicity. Although the genome of an industrial enzyme-producing A. niger strain (CBS 513.88) has already been sequenced, the versatility and diversity of this species compel additional exploration. We therefore undertook whole-genome sequencing of the acidogenic A. niger wild-type strain (ATCC 1015) and produced a genome sequence of very high quality. Only 15 gaps are present in the sequence, and half the telomeric regions have been elucidated. Moreover, sequence information from ATCC 1015 was used to improve the genome sequence of CBS 513.88. Chromosome-level comparisons uncovered several genome rearrangements, deletions, a clear case of strain-specific horizontal gene transfer, and identification of 0.8 Mb of novel sequence. Single nucleotide polymorphisms per kilobase (SNPs/kb) between the two strains were found to be exceptionally high (average: 7.8, maximum: 160 SNPs/kb). High variation within the species was confirmed with exo-metabolite profiling and phylogenetics. Detailed lists of alleles were generated, and genotypic differences were observed to accumulate in metabolic pathways essential to acid production and protein synthesis. A transcriptome analysis supported up-regulation of genes associated with biosynthesis of amino acids that are abundant in glucoamylase A, tRNA-synthases, and protein transporters in the protein producing CBS 513.88 strain. Our results and data sets from this integrative systems biology analysis resulted in a snapshot of fungal evolution and will support further optimization of cell factories based on filamentous fungi.
ESTHER : Andersen_2011_Genome.Res_21_885
PubMedSearch : Andersen_2011_Genome.Res_21_885
PubMedID: 21543515
Gene_locus related to this paper: aspna-g3y4g9 , aspna-g3yal2 , aspna-g3ycq2 , aspnc-a2qbh3 , aspnc-a2qe77 , aspnc-a2qf54 , aspnc-a2qfe9 , aspnc-a2qg33 , aspnc-a2qh76 , aspnc-a2qhe2 , aspnc-a2qi32 , aspnc-a2ql89 , aspnc-a2ql90 , aspnc-a2qla0 , aspnc-a2qmk5 , aspnc-a2qn56 , aspnc-a2qs22 , aspnc-a2qti9 , aspnc-a2qtz0 , aspnc-a2quc1 , aspnc-a2qx92 , aspnc-a2qyf0 , aspnc-a2qys7 , aspnc-a2qz72 , aspnc-a2qzn6 , aspnc-a2qzr0 , aspnc-a2qzx0 , aspnc-a2qzx4 , aspnc-a2r0p4 , aspnc-a2r1r5 , aspnc-a2r2i5 , aspnc-a2r5r4 , aspnc-a2r6h5 , aspnc-a2r8r3 , aspnc-a2r8z3 , aspnc-a2r273 , aspnc-a2r496 , aspnc-a2r502 , aspnc-a5abe5 , aspnc-a5abe8 , aspnc-a5abh9 , aspnc-a5abk1 , aspnc-axe1 , aspnc-cuti1 , aspnc-cuti2 , aspng-a2qs46 , aspng-a2qv27 , aspni-EstA , aspkw-g7y0v7 , aspnc-a2qt47 , aspnc-a2qt66 , aspna-g3xpq9 , aspnc-a2qqa1 , aspna-g3xsl3 , aspna-g3y5a6 , aspna-g3xpw9 , aspaw-a0a401kpx5 , aspnc-a2qw57 , aspaw-a0a401kcz4 , aspna-alba , aspna-azac

Title : Comparative genomics of the social amoebae Dictyostelium discoideum and Dictyostelium purpureum - Sucgang_2011_Genome.Biol_12_R20.1
Author(s) : Sucgang R , Kuo A , Tian X , Salerno W , Parikh A , Feasley CL , Dalin E , Tu H , Huang E , Barry K , Lindquist E , Shapiro H , Bruce D , Schmutz J , Salamov A , Fey P , Gaudet P , Anjard C , Babu MM , Basu S , Bushmanova Y , van der Wel H , Katoh-Kurasawa M , Dinh C , Coutinho PM , Saito T , Elias M , Schaap P , Kay RR , Henrissat B , Eichinger L , Rivero F , Putnam NH , West CM , Loomis WF , Chisholm RL , Shaulsky G , Strassmann JE , Queller DC , Kuspa A , Grigoriev IV
Ref : Genome Biol , 12 :R20 , 2011
Abstract : BACKGROUND: The social amoebae (Dictyostelia) are a diverse group of Amoebozoa that achieve multicellularity by aggregation and undergo morphogenesis into fruiting bodies with terminally differentiated spores and stalk cells. There are four groups of dictyostelids, with the most derived being a group that contains the model species Dictyostelium discoideum.
RESULTS: We have produced a draft genome sequence of another group dictyostelid, Dictyostelium purpureum, and compare it to the D. discoideum genome. The assembly (8.41 x coverage) comprises 799 scaffolds totaling 33.0 Mb, comparable to the D. discoideum genome size. Sequence comparisons suggest that these two dictyostelids shared a common ancestor approximately 400 million years ago. In spite of this divergence, most orthologs reside in small clusters of conserved synteny. Comparative analyses revealed a core set of orthologous genes that illuminate dictyostelid physiology, as well as differences in gene family content. Interesting patterns of gene conservation and divergence are also evident, suggesting function differences; some protein families, such as the histidine kinases, have undergone little functional change, whereas others, such as the polyketide synthases, have undergone extensive diversification. The abundant amino acid homopolymers encoded in both genomes are generally not found in homologous positions within proteins, so they are unlikely to derive from ancestral DNA triplet repeats. Genes involved in the social stage evolved more rapidly than others, consistent with either relaxed selection or accelerated evolution due to social conflict.
CONCLUSIONS: The findings from this new genome sequence and comparative analysis shed light on the biology and evolution of the Dictyostelia.
ESTHER : Sucgang_2011_Genome.Biol_12_R20.1
PubMedSearch : Sucgang_2011_Genome.Biol_12_R20.1
PubMedID: 21356102
Gene_locus related to this paper: dicpu-f0z7q0 , dicpu-f0z822 , dicpu-f0zfi0 , dicpu-f0zjs1 , dicpu-f0zks4 , dicpu-f0zmm3 , dicpu-f0zmm8 , dicpu-f0zmm9 , dicpu-f0zni7 , dicpu-f0znl3 , dicpu-f0zq90 , dicpu-f0zvn5 , dicpu-f0zxa4 , dicpu-f0zyf9 , dicpu-f1a3n5 , dicpu-f1a5b4 , dicpu-f1a269 , dicpu-f1a615 , dicpu-f0ztw9 , dicpu-f0zri3 , dicpu-f0zys7

Title : Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma - Kubicek_2011_Genome.Biol_12_R40
Author(s) : Kubicek CP , Herrera-Estrella A , Seidl-Seiboth V , Martinez DA , Druzhinina IS , Thon M , Zeilinger S , Casas-Flores S , Horwitz BA , Mukherjee PK , Mukherjee M , Kredics L , Alcaraz LD , Aerts A , Antal Z , Atanasova L , Cervantes-Badillo MG , Challacombe J , Chertkov O , McCluskey K , Coulpier F , Deshpande N , von Dohren H , Ebbole DJ , Esquivel-Naranjo EU , Fekete E , Flipphi M , Glaser F , Gomez-Rodriguez EY , Gruber S , Han C , Henrissat B , Hermosa R , Hernandez-Onate M , Karaffa L , Kosti I , Le Crom S , Lindquist E , Lucas S , Lubeck M , Lubeck PS , Margeot A , Metz B , Misra M , Nevalainen H , Omann M , Packer N , Perrone G , Uresti-Rivera EE , Salamov A , Schmoll M , Seiboth B , Shapiro H , Sukno S , Tamayo-Ramos JA , Tisch D , Wiest A , Wilkinson HH , Zhang M , Coutinho PM , Kenerley CM , Monte E , Baker SE , Grigoriev IV
Ref : Genome Biol , 12 :R40 , 2011
Abstract : BACKGROUND: Mycoparasitism, a lifestyle where one fungus is parasitic on another fungus, has special relevance when the prey is a plant pathogen, providing a strategy for biological control of pests for plant protection. Probably, the most studied biocontrol agents are species of the genus Hypocrea/Trichoderma.
RESULTS: Here we report an analysis of the genome sequences of the two biocontrol species Trichoderma atroviride (teleomorph Hypocrea atroviridis) and Trichoderma virens (formerly Gliocladium virens, teleomorph Hypocrea virens), and a comparison with Trichoderma reesei (teleomorph Hypocrea jecorina). These three Trichoderma species display a remarkable conservation of gene order (78 to 96%), and a lack of active mobile elements probably due to repeat-induced point mutation. Several gene families are expanded in the two mycoparasitic species relative to T. reesei or other ascomycetes, and are overrepresented in non-syntenic genome regions. A phylogenetic analysis shows that T. reesei and T. virens are derived relative to T. atroviride. The mycoparasitism-specific genes thus arose in a common Trichoderma ancestor but were subsequently lost in T. reesei.
CONCLUSIONS: The data offer a better understanding of mycoparasitism, and thus enforce the development of improved biocontrol strains for efficient and environmentally friendly protection of plants.
ESTHER : Kubicek_2011_Genome.Biol_12_R40
PubMedSearch : Kubicek_2011_Genome.Biol_12_R40
PubMedID: 21501500
Gene_locus related to this paper: hypai-g9nem6 , hypai-g9ng36 , hypai-g9ngu2 , hypai-g9nks5 , hypai-g9nks6 , hypai-g9nqe5 , hypai-g9nqk5 , hypai-g9nrx6 , hypai-g9nsx1 , hypai-g9ntn3 , hypai-g9nzc9 , hypai-g9nzd7 , hypai-g9p1t1 , hypai-g9p1v2 , hypai-g9p2n8 , hypai-g9p4z2 , hypai-g9p878 , hypai-g9pa17 , hypai-g9pbz9 , hypvg-g9mem8 , hypvg-g9mg52 , hypvg-g9mga2 , hypvg-g9mhi3 , hypvg-g9mjc7 , hypvg-g9mk44 , hypvg-g9mms1 , hypvg-g9mnf0 , hypvg-g9mng3 , hypvg-g9mpt0 , hypvg-g9mrp9 , hypvg-g9ms16 , hypvg-g9ms32 , hypvg-g9msv5 , hypvg-g9muh6 , hypvg-g9muk0 , hypvg-g9mwe2 , hypvg-g9my79 , hypvg-g9n0p7 , hypvg-g9n2g3 , hypvg-g9n2g4 , hypvg-g9n4k5 , hypvg-g9n9n0 , hypvg-g9n561 , hypvg-g9n988 , hypvg-g9nb12 , hypvg-g9nb54 , hypvg-g9nbh8 , hypai-g9npz7 , hypai-g9njw6 , hypvg-g9mx08 , hypvg-g9mlt2 , hypai-g9p4j3 , hypvg-g9nbd3 , hypai-g9nxf6 , hypvg-g9n3y9 , hypvg-g9mgs4 , hypai-g9p6m2 , hypvg-g9my62 , hypvg-g9nbv2 , hypvg-g9my22 , hypai-g9p2e2 , hypai-g9p596 , hypai-g9nf87 , hypvg-g9me87 , hypvg-g9ndn9 , hypai-g9niy5 , hypai-g9ntx6 , hypvg-g9n3e7 , hypai-g9nu29 , hypvg-g9n2z0 , hypvg-g9ndf4 , 9hypo-a0a2p4zt82 , hypvg-g9n0g0 , hypvg-g9muj2 , hypvg-g9mud0 , hypai-g9nkx5

Title : The ecoresponsive genome of Daphnia pulex - Colbourne_2011_Science_331_555
Author(s) : Colbourne JK , Pfrender ME , Gilbert D , Thomas WK , Tucker A , Oakley TH , Tokishita S , Aerts A , Arnold GJ , Basu MK , Bauer DJ , Caceres CE , Carmel L , Casola C , Choi JH , Detter JC , Dong Q , Dusheyko S , Eads BD , Frohlich T , Geiler-Samerotte KA , Gerlach D , Hatcher P , Jogdeo S , Krijgsveld J , Kriventseva EV , Kultz D , Laforsch C , Lindquist E , Lopez J , Manak JR , Muller J , Pangilinan J , Patwardhan RP , Pitluck S , Pritham EJ , Rechtsteiner A , Rho M , Rogozin IB , Sakarya O , Salamov A , Schaack S , Shapiro H , Shiga Y , Skalitzky C , Smith Z , Souvorov A , Sung W , Tang Z , Tsuchiya D , Tu H , Vos H , Wang M , Wolf YI , Yamagata H , Yamada T , Ye Y , Shaw JR , Andrews J , Crease TJ , Tang H , Lucas SM , Robertson HM , Bork P , Koonin EV , Zdobnov EM , Grigoriev IV , Lynch M , Boore JL
Ref : Science , 331 :555 , 2011
Abstract : We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200 megabases and contains at least 30,907 genes. The high gene count is a consequence of an elevated rate of gene duplication resulting in tandem gene clusters. More than a third of Daphnia's genes have no detectable homologs in any other available proteome, and the most amplified gene families are specific to the Daphnia lineage. The coexpansion of gene families interacting within metabolic pathways suggests that the maintenance of duplicated genes is not random, and the analysis of gene expression under different environmental conditions reveals that numerous paralogs acquire divergent expression patterns soon after duplication. Daphnia-specific genes, including many additional loci within sequenced regions that are otherwise devoid of annotations, are the most responsive genes to ecological challenges.
ESTHER : Colbourne_2011_Science_331_555
PubMedSearch : Colbourne_2011_Science_331_555
PubMedID: 21292972
Gene_locus related to this paper: dappu-e9fut0 , dappu-e9fut9 , dappu-e9fvw6 , dappu-e9fxt4 , dappu-e9fyr6 , dappu-e9fzg6 , dappu-e9g1e2 , dappu-e9g1e6 , dappu-e9g1e7 , dappu-e9g1e8 , dappu-e9g1v3 , dappu-e9g1z2 , dappu-e9gb99 , dappu-e9gba0 , dappu-e9gcb4 , dappu-e9gdv5 , dappu-e9gdv7 , dappu-e9gi24 , dappu-e9gj77 , dappu-e9gja7 , dappu-e9gmp5 , dappu-e9gmr0 , dappu-e9gn32 , dappu-e9gp76 , dappu-e9gp82 , dappu-e9gp98 , dappu-e9gp99 , dappu-e9gvl2 , dappu-e9gzn7 , dappu-e9h1p4 , dappu-e9h2c8 , dappu-e9h2c9 , dappu-e9h6x9 , dappu-e9h6y4 , dappu-e9h7w9 , dappu-e9h8r4 , dappu-e9hd06 , dappu-e9hh56 , dappu-e9hh57 , dappu-e9hh59 , dappu-e9hmp4 , dappu-e9hp64 , dappu-e9hp65 , dappu-e9hpy8 , dappu-e9htg8 , dapul-ACHE1 , dapul-ACHE2 , dappu-e9gnj1 , dappu-e9gu36 , dappu-e9hpc4 , dappu-e9gb07 , dappu-e9glp6 , dappu-e9glp5 , dappu-e9gjv2 , dappu-e9h0c7 , dappu-e9g4g2 , dappu-e9gw69 , dappu-e9h3h9 , dappu-e9g545 , dappu-e9gw71 , dappu-e9gw68 , dappu-e9h3e7 , dappu-e9gfg9 , dappu-e9fvy6 , dappu-e9hgt2

Title : The genome of Tetranychus urticae reveals herbivorous pest adaptations - Grbic_2011_Nature_479_487
Author(s) : Grbic M , Van Leeuwen T , Clark RM , Rombauts S , Rouze P , Grbic V , Osborne EJ , Dermauw W , Ngoc PC , Ortego F , Hernandez-Crespo P , Diaz I , Martinez M , Navajas M , Sucena E , Magalhaes S , Nagy L , Pace RM , Djuranovic S , Smagghe G , Iga M , Christiaens O , Veenstra JA , Ewer J , Villalobos RM , Hutter JL , Hudson SD , Velez M , Yi SV , Zeng J , Pires-daSilva A , Roch F , Cazaux M , Navarro M , Zhurov V , Acevedo G , Bjelica A , Fawcett JA , Bonnet E , Martens C , Baele G , Wissler L , Sanchez-Rodriguez A , Tirry L , Blais C , Demeestere K , Henz SR , Gregory TR , Mathieu J , Verdon L , Farinelli L , Schmutz J , Lindquist E , Feyereisen R , Van de Peer Y
Ref : Nature , 479 :487 , 2011
Abstract : The spider mite Tetranychus urticae is a cosmopolitan agricultural pest with an extensive host plant range and an extreme record of pesticide resistance. Here we present the completely sequenced and annotated spider mite genome, representing the first complete chelicerate genome. At 90 megabases T. urticae has the smallest sequenced arthropod genome. Compared with other arthropods, the spider mite genome shows unique changes in the hormonal environment and organization of the Hox complex, and also reveals evolutionary innovation of silk production. We find strong signatures of polyphagy and detoxification in gene families associated with feeding on different hosts and in new gene families acquired by lateral gene transfer. Deep transcriptome analysis of mites feeding on different plants shows how this pest responds to a changing host environment. The T. urticae genome thus offers new insights into arthropod evolution and plant-herbivore interactions, and provides unique opportunities for developing novel plant protection strategies.
ESTHER : Grbic_2011_Nature_479_487
PubMedSearch : Grbic_2011_Nature_479_487
PubMedID: 22113690
Gene_locus related to this paper: tetur-ACHE

Title : The Selaginella genome identifies genetic changes associated with the evolution of vascular plants - Banks_2011_Science_332_960
Author(s) : Banks JA , Nishiyama T , Hasebe M , Bowman JL , Gribskov M , dePamphilis C , Albert VA , Aono N , Aoyama T , Ambrose BA , Ashton NW , Axtell MJ , Barker E , Barker MS , Bennetzen JL , Bonawitz ND , Chapple C , Cheng C , Correa LG , Dacre M , DeBarry J , Dreyer I , Elias M , Engstrom EM , Estelle M , Feng L , Finet C , Floyd SK , Frommer WB , Fujita T , Gramzow L , Gutensohn M , Harholt J , Hattori M , Heyl A , Hirai T , Hiwatashi Y , Ishikawa M , Iwata M , Karol KG , Koehler B , Kolukisaoglu U , Kubo M , Kurata T , Lalonde S , Li K , Li Y , Litt A , Lyons E , Manning G , Maruyama T , Michael TP , Mikami K , Miyazaki S , Morinaga S , Murata T , Mueller-Roeber B , Nelson DR , Obara M , Oguri Y , Olmstead RG , Onodera N , Petersen BL , Pils B , Prigge M , Rensing SA , Riano-Pachon DM , Roberts AW , Sato Y , Scheller HV , Schulz B , Schulz C , Shakirov EV , Shibagaki N , Shinohara N , Shippen DE , Sorensen I , Sotooka R , Sugimoto N , Sugita M , Sumikawa N , Tanurdzic M , Theissen G , Ulvskov P , Wakazuki S , Weng JK , Willats WW , Wipf D , Wolf PG , Yang L , Zimmer AD , Zhu Q , Mitros T , Hellsten U , Loque D , Otillar R , Salamov A , Schmutz J , Shapiro H , Lindquist E , Lucas S , Rokhsar D , Grigoriev IV
Ref : Science , 332 :960 , 2011
Abstract : Vascular plants appeared ~410 million years ago, then diverged into several lineages of which only two survive: the euphyllophytes (ferns and seed plants) and the lycophytes. We report here the genome sequence of the lycophyte Selaginella moellendorffii (Selaginella), the first nonseed vascular plant genome reported. By comparing gene content in evolutionarily diverse taxa, we found that the transition from a gametophyte- to a sporophyte-dominated life cycle required far fewer new genes than the transition from a nonseed vascular to a flowering plant, whereas secondary metabolic genes expanded extensively and in parallel in the lycophyte and angiosperm lineages. Selaginella differs in posttranscriptional gene regulation, including small RNA regulation of repetitive elements, an absence of the trans-acting small interfering RNA pathway, and extensive RNA editing of organellar genes.
ESTHER : Banks_2011_Science_332_960
PubMedSearch : Banks_2011_Science_332_960
PubMedID: 21551031
Gene_locus related to this paper: selml-d8qua5 , selml-d8qva1 , selml-d8qyh7 , selml-d8qza0 , selml-d8r5d4 , selml-d8r6d4 , selml-d8r504 , selml-d8r506 , selml-d8rbi1 , selml-d8rbs1 , selml-d8rck8 , selml-d8rf38 , selml-d8rkl6 , selml-d8rpr1 , selml-d8rpy0 , selml-d8ru47 , selml-d8ry54 , selml-d8rzp6 , selml-d8rzy7 , selml-d8s0c9 , selml-d8s0u3 , selml-d8s2t1 , selml-d8s3z8 , selml-d8s401 , selml-d8sba6 , selml-d8sch9 , selml-d8spq2 , selml-d8sq37 , selml-d8ssx7 , selml-d8swp2 , selml-d8t7a3 , selml-d8t8v4 , selml-d8taz4 , selml-d8tdq6 , selml-d8rai8 , selml-d8qt54 , selml-d8r2d8 , selml-d8rmd3 , selml-d8rra9 , selml-d8slg4 , selml-d8swp0 , selml-d8s7i0 , selml-d8qz37 , selml-d8sz00 , selml-d8s776 , selml-d8qw15 , selml-d8ska7 , selml-d8t0c4 , selml-d8r194 , selml-d8s5m8 , selml-d8s7r2 , selml-d8ta80 , selml-d8ru55

Title : The plant cell wall-decomposing machinery underlies the functional diversity of forest fungi - Eastwood_2011_Science_333_762
Author(s) : Eastwood DC , Floudas D , Binder M , Majcherczyk A , Schneider P , Aerts A , Asiegbu FO , Baker SE , Barry K , Bendiksby M , Blumentritt M , Coutinho PM , Cullen D , de Vries RP , Gathman A , Goodell B , Henrissat B , Ihrmark K , Kauserud H , Kohler A , LaButti K , Lapidus A , Lavin JL , Lee YH , Lindquist E , Lilly W , Lucas S , Morin E , Murat C , Oguiza JA , Park J , Pisabarro AG , Riley R , Rosling A , Salamov A , Schmidt O , Schmutz J , Skrede I , Stenlid J , Wiebenga A , Xie X , Kues U , Hibbett DS , Hoffmeister D , Hogberg N , Martin F , Grigoriev IV , Watkinson SC
Ref : Science , 333 :762 , 2011
Abstract : Brown rot decay removes cellulose and hemicellulose from wood--residual lignin contributing up to 30% of forest soil carbon--and is derived from an ancestral white rot saprotrophy in which both lignin and cellulose are decomposed. Comparative and functional genomics of the "dry rot" fungus Serpula lacrymans, derived from forest ancestors, demonstrated that the evolution of both ectomycorrhizal biotrophy and brown rot saprotrophy were accompanied by reductions and losses in specific protein families, suggesting adaptation to an intercellular interaction with plant tissue. Transcriptome and proteome analysis also identified differences in wood decomposition in S. lacrymans relative to the brown rot Postia placenta. Furthermore, fungal nutritional mode diversification suggests that the boreal forest biome originated via genetic coevolution of above- and below-ground biota.
ESTHER : Eastwood_2011_Science_333_762
PubMedSearch : Eastwood_2011_Science_333_762
PubMedID: 21764756
Gene_locus related to this paper: serl3-f8prj2 , serl3-f8qcc4 , serl9-f8ngp6 , serl9-f8nhd7 , serl9-f8nhq9 , serl9-f8nq77 , serl9-f8nr67 , serl9-f8nrt5 , serl9-f8nvy7.1 , serl9-f8nvy7.2 , serl9-f8nvy8 , serl9-f8nxt0.1 , serl9-f8nxt0.2 , serl9-f8nzr3 , serl9-f8p0f0 , serl9-f8p6v0 , serl9-f8p015 , serl9-f8p018 , serl9-f8p386 , serl9-f8paz8 , serl9-f8pbv1 , serl9-f8pby1 , serl9-f8pc25 , serl9-f8pc39 , serl9-f8nia7 , serl3-f8pju2 , serl9-f8peh1 , serl9-nps3

Title : Comparative genomic analysis of the thermophilic biomass-degrading fungi Myceliophthora thermophila and Thielavia terrestris - Berka_2011_Nat.Biotechnol_29_922
Author(s) : Berka RM , Grigoriev IV , Otillar R , Salamov A , Grimwood J , Reid I , Ishmael N , John T , Darmond C , Moisan MC , Henrissat B , Coutinho PM , Lombard V , Natvig DO , Lindquist E , Schmutz J , Lucas S , Harris P , Powlowski J , Bellemare A , Taylor D , Butler G , de Vries RP , Allijn IE , van den Brink J , Ushinsky S , Storms R , Powell AJ , Paulsen IT , Elbourne LD , Baker SE , Magnuson J , Laboissiere S , Clutterbuck AJ , Martinez D , Wogulis M , de Leon AL , Rey MW , Tsang A
Ref : Nat Biotechnol , 29 :922 , 2011
Abstract : Thermostable enzymes and thermophilic cell factories may afford economic advantages in the production of many chemicals and biomass-based fuels. Here we describe and compare the genomes of two thermophilic fungi, Myceliophthora thermophila and Thielavia terrestris. To our knowledge, these genomes are the first described for thermophilic eukaryotes and the first complete telomere-to-telomere genomes for filamentous fungi. Genome analyses and experimental data suggest that both thermophiles are capable of hydrolyzing all major polysaccharides found in biomass. Examination of transcriptome data and secreted proteins suggests that the two fungi use shared approaches in the hydrolysis of cellulose and xylan but distinct mechanisms in pectin degradation. Characterization of the biomass-hydrolyzing activity of recombinant enzymes suggests that these organisms are highly efficient in biomass decomposition at both moderate and high temperatures. Furthermore, we present evidence suggesting that aside from representing a potential reservoir of thermostable enzymes, thermophilic fungi are amenable to manipulation using classical and molecular genetics.
ESTHER : Berka_2011_Nat.Biotechnol_29_922
PubMedSearch : Berka_2011_Nat.Biotechnol_29_922
PubMedID: 21964414
Gene_locus related to this paper: thiha-cip2 , thite-g2r8b5 , thite-g2rcm8 , thite-g2r192 , thiha-g2qdy2 , thiha-g2qh51 , thite-g2rae6 , thite-g2r5h0 , thiha-g2qj94 , thiha-g2qnb2 , thite-g2rg14 , myctt-g2q973 , thite-g2qtu3 , myctt-g2qpr0 , thite-g2rhm0 , 9pezi-a0a3s4b069 , myctt-g2qmb4 , thett-g2qur2

Title : The genome of the Western clawed frog Xenopus tropicalis - Hellsten_2010_Science_328_633
Author(s) : Hellsten U , Harland RM , Gilchrist MJ , Hendrix D , Jurka J , Kapitonov V , Ovcharenko I , Putnam NH , Shu S , Taher L , Blitz IL , Blumberg B , Dichmann DS , Dubchak I , Amaya E , Detter JC , Fletcher R , Gerhard DS , Goodstein D , Graves T , Grigoriev IV , Grimwood J , Kawashima T , Lindquist E , Lucas SM , Mead PE , Mitros T , Ogino H , Ohta Y , Poliakov AV , Pollet N , Robert J , Salamov A , Sater AK , Schmutz J , Terry A , Vize PD , Warren WC , Wells D , Wills A , Wilson RK , Zimmerman LB , Zorn AM , Grainger R , Grammer T , Khokha MK , Richardson PM , Rokhsar DS
Ref : Science , 328 :633 , 2010
Abstract : The western clawed frog Xenopus tropicalis is an important model for vertebrate development that combines experimental advantages of the African clawed frog Xenopus laevis with more tractable genetics. Here we present a draft genome sequence assembly of X. tropicalis. This genome encodes more than 20,000 protein-coding genes, including orthologs of at least 1700 human disease genes. Over 1 million expressed sequence tags validated the annotation. More than one-third of the genome consists of transposable elements, with unusually prevalent DNA transposons. Like that of other tetrapods, the genome of X. tropicalis contains gene deserts enriched for conserved noncoding elements. The genome exhibits substantial shared synteny with human and chicken over major parts of large chromosomes, broken by lineage-specific chromosome fusions and fissions, mainly in the mammalian lineage.
ESTHER : Hellsten_2010_Science_328_633
PubMedSearch : Hellsten_2010_Science_328_633
PubMedID: 20431018
Gene_locus related to this paper: xenla-q6pcj9 , xentr-a9umk0 , xentr-abhdb , xentr-ACHE , xentr-b0bm77 , xentr-b1h0y7 , xentr-b2guc4 , xentr-b7zt03 , xentr-b7ztj4 , xentr-BCHE1 , xentr-BCHE2 , xentr-cxest2 , xentr-d2x2k4 , xentr-d2x2k6 , xentr-f6rff6 , xentr-f6v0g3 , xentr-f6v2j6 , xentr-f6v3z1 , xentr-f6y4c8 , xentr-f6yve5 , xentr-f7a4y9 , xentr-f7acc5 , xentr-f7e2e2 , xentr-LOC394897 , xentr-ndrg1 , xentr-q0vfb6 , xentr-f7cpl7 , xentr-f6yj44 , xentr-f7ejk4 , xentr-f6q8j8 , xentr-f6z8f0 , xentr-f7d709 , xentr-b0bmb8 , xentr-f7af63 , xentr-a0a1b8y2w9 , xentr-f7d4k9 , xentr-f6r032 , xentr-f6yvq3 , xentr-a0a1b8y2z3 , xentr-f7afg4 , xentr-f6xb15 , xentr-f7e1r2 , xentr-a4ihf1 , xentr-f7eue5 , xentr-f6u7u3 , xentr-f172a , xentr-f7equ8 , xentr-f7dd89 , xentr-a9jtx5

Title : Genomic analysis of organismal complexity in the multicellular green alga Volvox carteri - Prochnik_2010_Science_329_223
Author(s) : Prochnik SE , Umen J , Nedelcu AM , Hallmann A , Miller SM , Nishii I , Ferris P , Kuo A , Mitros T , Fritz-Laylin LK , Hellsten U , Chapman J , Simakov O , Rensing SA , Terry A , Pangilinan J , Kapitonov V , Jurka J , Salamov A , Shapiro H , Schmutz J , Grimwood J , Lindquist E , Lucas S , Grigoriev IV , Schmitt R , Kirk D , Rokhsar DS
Ref : Science , 329 :223 , 2010
Abstract : The multicellular green alga Volvox carteri and its morphologically diverse close relatives (the volvocine algae) are well suited for the investigation of the evolution of multicellularity and development. We sequenced the 138-mega-base pair genome of V. carteri and compared its approximately 14,500 predicted proteins to those of its unicellular relative Chlamydomonas reinhardtii. Despite fundamental differences in organismal complexity and life history, the two species have similar protein-coding potentials and few species-specific protein-coding gene predictions. Volvox is enriched in volvocine-algal-specific proteins, including those associated with an expanded and highly compartmentalized extracellular matrix. Our analysis shows that increases in organismal complexity can be associated with modifications of lineage-specific proteins rather than large-scale invention of protein-coding capacity.
ESTHER : Prochnik_2010_Science_329_223
PubMedSearch : Prochnik_2010_Science_329_223
PubMedID: 20616280
Gene_locus related to this paper: volca-d8tmz1 , volca-d8tne9 , volca-d8tnn6 , volca-d8tns6 , volca-d8tr92 , volca-d8u2d3 , volca-d8u5r0 , volca-d8u7s7 , volca-d8u7s8 , volca-d8u9w4 , volca-d8u460 , volca-d8uab7 , volca-d8uai0 , volca-d8uev0 , volca-d8uhi9 , volca-d8uiw9 , volca-d8ujv0 , volca-d8uf23 , volca-d8tmz9 , volca-d8u6e0

Title : The genome of Naegleria gruberi illuminates early eukaryotic versatility - Fritz-Laylin_2010_Cell_140_631
Author(s) : Fritz-Laylin LK , Prochnik SE , Ginger ML , Dacks JB , Carpenter ML , Field MC , Kuo A , Paredez A , Chapman J , Pham J , Shu S , Neupane R , Cipriano M , Mancuso J , Tu H , Salamov A , Lindquist E , Shapiro H , Lucas S , Grigoriev IV , Cande WZ , Fulton C , Rokhsar DS , Dawson SC
Ref : Cell , 140 :631 , 2010
Abstract : Genome sequences of diverse free-living protists are essential for understanding eukaryotic evolution and molecular and cell biology. The free-living amoeboflagellate Naegleria gruberi belongs to a varied and ubiquitous protist clade (Heterolobosea) that diverged from other eukaryotic lineages over a billion years ago. Analysis of the 15,727 protein-coding genes encoded by Naegleria's 41 Mb nuclear genome indicates a capacity for both aerobic respiration and anaerobic metabolism with concomitant hydrogen production, with fundamental implications for the evolution of organelle metabolism. The Naegleria genome facilitates substantially broader phylogenomic comparisons of free-living eukaryotes than previously possible, allowing us to identify thousands of genes likely present in the pan-eukaryotic ancestor, with 40% likely eukaryotic inventions. Moreover, we construct a comprehensive catalog of amoeboid-motility genes. The Naegleria genome, analyzed in the context of other protists, reveals a remarkably complex ancestral eukaryote with a rich repertoire of cytoskeletal, sexual, signaling, and metabolic modules.
ESTHER : Fritz-Laylin_2010_Cell_140_631
PubMedSearch : Fritz-Laylin_2010_Cell_140_631
PubMedID: 20211133
Gene_locus related to this paper: naegr-d2ux86 , naegr-d2uyl7 , naegr-d2uyn1 , naegr-d2uzk6 , naegr-d2uzp4 , naegr-d2v1m1 , naegr-d2v3p5 , naegr-d2v5p1 , naegr-d2v6f6 , naegr-d2v6y9 , naegr-d2v8x8 , naegr-d2v186 , naegr-d2v339 , naegr-d2v556 , naegr-d2vbq7 , naegr-d2vdq6 , naegr-d2ve51 , naegr-d2vga2 , naegr-d2vgm9 , naegr-d2vh14 , naegr-d2vha2 , naegr-d2vj80 , naegr-d2vjj7 , naegr-d2vl41 , naegr-d2vmj5 , naegr-d2vms7 , naegr-d2vqi5 , naegr-d2vr44 , naegr-d2vrq2 , naegr-d2vs01 , naegr-d2vs58 , naegr-d2vts5 , naegr-d2vu69 , naegr-d2vvg8 , naegr-d2vxp2 , naegr-d2vyl1 , naegr-d2vzy5 , naegr-d2w0l5 , naegr-d2w0v9 , naegr-d2w3g8 , naegr-d2w3v7 , naegr-d2w3v8 , naegr-d2vct1

Title : Genome sequence of the model mushroom Schizophyllum commune - Ohm_2010_Nat.Biotechnol_28_957
Author(s) : Ohm RA , de Jong JF , Lugones LG , Aerts A , Kothe E , Stajich JE , de Vries RP , Record E , Levasseur A , Baker SE , Bartholomew KA , Coutinho PM , Erdmann S , Fowler TJ , Gathman AC , Lombard V , Henrissat B , Knabe N , Kues U , Lilly WW , Lindquist E , Lucas S , Magnuson JK , Piumi F , Raudaskoski M , Salamov A , Schmutz J , Schwarze FW , vanKuyk PA , Horton JS , Grigoriev IV , Wosten HA
Ref : Nat Biotechnol , 28 :957 , 2010
Abstract : Much remains to be learned about the biology of mushroom-forming fungi, which are an important source of food, secondary metabolites and industrial enzymes. The wood-degrading fungus Schizophyllum commune is both a genetically tractable model for studying mushroom development and a likely source of enzymes capable of efficient degradation of lignocellulosic biomass. Comparative analyses of its 38.5-megabase genome, which encodes 13,210 predicted genes, reveal the species's unique wood-degrading machinery. One-third of the 471 genes predicted to encode transcription factors are differentially expressed during sexual development of S. commune. Whereas inactivation of one of these, fst4, prevented mushroom formation, inactivation of another, fst3, resulted in more, albeit smaller, mushrooms than in the wild-type fungus. Antisense transcripts may also have a role in the formation of fruiting bodies. Better insight into the mechanisms underlying mushroom formation should affect commercial production of mushrooms and their industrial use for producing enzymes and pharmaceuticals.
ESTHER : Ohm_2010_Nat.Biotechnol_28_957
PubMedSearch : Ohm_2010_Nat.Biotechnol_28_957
PubMedID: 20622885
Gene_locus related to this paper: schcm-d8pqz6 , schcm-d8prj2 , schcm-d8pug6 , schcm-d8pxe8 , schcm-d8pxe9 , schcm-d8pxz1 , schcm-d8q1c7 , schcm-d8q2b4 , schcm-d8q3j1 , schcm-d8q5m5 , schcm-d8q7x7.1 , schcm-d8q7x7.2 , schcm-d8q8y8 , schcm-d8q9n6 , schcm-d8q697 , schcm-d8qip8 , schcm-d8q5s5 , schcm-d8ppb3 , schcm-d8ppb6 , schcm-d8pv73 , schcm-d8pzm1 , schcm-d8q5a7 , schcm-d8qif0

Title : Genome sequencing and analysis of the model grass Brachypodium distachyon. -
Author(s) : Vogel JP , Garvin DF , Mockler TC , Schmutz J , Rokhsar D , Bevan MW , Barry K , Lucas S , Harmon-Smith M , Lail K , Tice H , Grimwood J , McKenzie N , Huo N , Gu YQ , Lazo GR , Anderson OD , You FM , Luo MC , Dvorak J , Wright J , Febrer M , Idziak D , Hasterok R , Lindquist E , Wang M , Fox SE , Priest HD , Filichkin SA , Givan SA , Bryant DW , Chang JH , Wu H , Wu W , Hsia AP , Schnable PS , Kalyanaraman A , Barbazuk B , Michael TP , Hazen SP , Bragg JN , Laudencia-Chingcuanco D , Weng Y , Haberer G , Spannagl M , Mayer K , Rattei T , Mitros T , Lee SJ , Rose JK , Mueller LA , York TL , Wicker T , Buchmann JP , Tanskanen J , Schulman AH , Gundlach H , Bevan M , de Oliveira AC , Maia Lda C , Belknap W , Jiang N , Lai J , Zhu L , Ma J , Sun C , Pritham E , Salse J , Murat F , Abrouk M , Bruggmann R , Messing J , Fahlgren N , Sullivan CM , Carrington JC , Chapman EJ , May GD , Zhai J , Ganssmann M , Gurazada SG , German M , Meyers BC , Green PJ , Tyler L , Wu J , Thomson J , Chen S , Scheller HV , Harholt J , Ulvskov P , Kimbrel JA , Bartley LE , Cao P , Jung KH , Sharma MK , Vega-Sanchez M , Ronald P , Dardick CD , De Bodt S , Verelst W , Inz D , Heese M , Schnittger A , Yang X , Kalluri UC , Tuskan GA , Hua Z , Vierstra RD , Cui Y , Ouyang S , Sun Q , Liu Z , Yilmaz A , Grotewold E , Sibout R , Hematy K , Mouille G , Hofte H , Michael T , Pelloux J , O'Connor D , Schnable J , Rowe S , Harmon F , Cass CL , Sedbrook JC , Byrne ME , Walsh S , Higgins J , Li P , Brutnell T , Unver T , Budak H , Belcram H , Charles M , Chalhoub B , Baxter I
Ref : Nature , 463 :763 , 2010
PubMedID: 20148030
Gene_locus related to this paper: bradi-i1grm0 , bradi-i1gx82 , bradi-i1hb80 , bradi-i1hkv6 , bradi-i1hpu6 , bradi-i1i3e4 , bradi-i1i9i0 , bradi-i1i435 , bradi-i1ix93 , bradi-i1gsk6 , bradi-i1hk44 , bradi-i1hk45 , bradi-i1hnk7 , bradi-i1hsd5 , bradi-i1huy4 , bradi-i1huy9 , bradi-i1huz0 , bradi-i1gxx9 , bradi-i1hl25 , bradi-i1hcw7 , bradi-i1hyv6 , bradi-i1hyb5 , bradi-i1hvr8 , bradi-i1hmu2 , bradi-i1hf05 , bradi-i1gry7 , bradi-i1hf06 , bradi-i1i5z8 , bradi-i1icy3 , bradi-i1j1h3 , bradi-i1h1e3 , bradi-i1hvr9 , bradi-a0a0q3r7i7 , bradi-i1i377 , bradi-i1hjg5 , bradi-i1h3i9 , bradi-i1gsg5 , bradi-a0a0q3mph9 , bradi-i1h682 , bradi-a0a0q3lc91 , bradi-i1gx49 , bradi-i1i839 , bradi-a0a2k2dsp5 , bradi-i1gsb5

Title : The Chlorella variabilis NC64A genome reveals adaptation to photosymbiosis, coevolution with viruses, and cryptic sex - Blanc_2010_Plant.Cell_22_2943
Author(s) : Blanc G , Duncan G , Agarkova I , Borodovsky M , Gurnon J , Kuo A , Lindquist E , Lucas S , Pangilinan J , Polle J , Salamov A , Terry A , Yamada T , Dunigan DD , Grigoriev IV , Claverie JM , Van Etten JL
Ref : Plant Cell , 22 :2943 , 2010
Abstract : Chlorella variabilis NC64A, a unicellular photosynthetic green alga (Trebouxiophyceae), is an intracellular photobiont of Paramecium bursaria and a model system for studying virus/algal interactions. We sequenced its 46-Mb nuclear genome, revealing an expansion of protein families that could have participated in adaptation to symbiosis. NC64A exhibits variations in GC content across its genome that correlate with global expression level, average intron size, and codon usage bias. Although Chlorella species have been assumed to be asexual and nonmotile, the NC64A genome encodes all the known meiosis-specific proteins and a subset of proteins found in flagella. We hypothesize that Chlorella might have retained a flagella-derived structure that could be involved in sexual reproduction. Furthermore, a survey of phytohormone pathways in chlorophyte algae identified algal orthologs of Arabidopsis thaliana genes involved in hormone biosynthesis and signaling, suggesting that these functions were established prior to the evolution of land plants. We show that the ability of Chlorella to produce chitinous cell walls likely resulted from the capture of metabolic genes by horizontal gene transfer from algal viruses, prokaryotes, or fungi. Analysis of the NC64A genome substantially advances our understanding of the green lineage evolution, including the genomic interplay with viruses and symbiosis between eukaryotes.
ESTHER : Blanc_2010_Plant.Cell_22_2943
PubMedSearch : Blanc_2010_Plant.Cell_22_2943
PubMedID: 20852019
Gene_locus related to this paper: chlva-e1z3j3 , chlva-e1z3n9 , chlva-e1z620 , chlva-e1z882 , chlva-e1zd56 , chlva-e1zdd9 , chlva-e1zde0 , chlva-e1ze02 , chlva-e1zeh7 , chlva-e1zhu4 , chlva-e1zie3 , chlva-e1zii9 , chlva-e1zmj6 , chlva-e1ztt0 , chlva-e1z5k1 , chlva-e1ztf4

Title : Genome sequence of the palaeopolyploid soybean - Schmutz_2010_Nature_463_178
Author(s) : Schmutz J , Cannon SB , Schlueter J , Ma J , Mitros T , Nelson W , Hyten DL , Song Q , Thelen JJ , Cheng J , Xu D , Hellsten U , May GD , Yu Y , Sakurai T , Umezawa T , Bhattacharyya MK , Sandhu D , Valliyodan B , Lindquist E , Peto M , Grant D , Shu S , Goodstein D , Barry K , Futrell-Griggs M , Abernathy B , Du J , Tian Z , Zhu L , Gill N , Joshi T , Libault M , Sethuraman A , Zhang XC , Shinozaki K , Nguyen HT , Wing RA , Cregan P , Specht J , Grimwood J , Rokhsar D , Stacey G , Shoemaker RC , Jackson SA
Ref : Nature , 463 :178 , 2010
Abstract : Soybean (Glycine max) is one of the most important crop plants for seed protein and oil content, and for its capacity to fix atmospheric nitrogen through symbioses with soil-borne microorganisms. We sequenced the 1.1-gigabase genome by a whole-genome shotgun approach and integrated it with physical and high-density genetic maps to create a chromosome-scale draft sequence assembly. We predict 46,430 protein-coding genes, 70% more than Arabidopsis and similar to the poplar genome which, like soybean, is an ancient polyploid (palaeopolyploid). About 78% of the predicted genes occur in chromosome ends, which comprise less than one-half of the genome but account for nearly all of the genetic recombination. Genome duplications occurred at approximately 59 and 13 million years ago, resulting in a highly duplicated genome with nearly 75% of the genes present in multiple copies. The two duplication events were followed by gene diversification and loss, and numerous chromosome rearrangements. An accurate soybean genome sequence will facilitate the identification of the genetic basis of many soybean traits, and accelerate the creation of improved soybean varieties.
ESTHER : Schmutz_2010_Nature_463_178
PubMedSearch : Schmutz_2010_Nature_463_178
PubMedID: 20075913
Gene_locus related to this paper: soybn-c6t4m5 , soybn-c6t4p4 , soybn-c6tav4 , soybn-c6tdf9 , soybn-c6tiz7 , soybn-c6tmg3 , soybn-i1jgq5 , soybn-i1kpj2 , soybn-i1kwe7 , soybn-i1l7e3 , soybn-i1l497 , soybn-i1ll09 , soybn-i1lpi4 , soybn-i1jcw2 , soybn-i1jcw3 , soybn-i1jcw4 , soybn-i1jcw7 , soybn-i1k217 , soybn-i1kfz3 , soybn-i1lhi0 , soybn-k7k6s4 , soybn-i1jtw1 , soybn-c6tas4 , soybn-i1m910 , soybn-c6t7k8 , soybn-i1k636 , soybn-i1kju7 , soybn-i1j4c6 , soybn-i1lbk2 , soybn-i1jqy5 , soybn-i1nbj8 , soybn-i1j855 , soybn-i1l5a3 , soybn-k7mt28 , soybn-i1lau7 , soybn-i1lay0 , soybn-i1net3 , soybn-i1jr09 , soybn-i1ms08 , soybn-i1mmh5 , soybn-i1mly5 , soybn-i1mmh3 , soybn-i1mmh4 , soybn-i1ngu7 , soybn-k7ll20 , soybn-i1mly4 , soybn-a0a0r0i9y7 , soybn-a0a0r0j241 , soybn-i1les8 , soybn-k7n313 , soybn-i1kfj1 , soybn-a0a0r0k7x4 , soybn-i1ly30 , soybn-i1mwr8 , soybn-i1kfg5 , soybn-i1kly2 , soybn-a0a0r0ixi2 , soybn-i1jew0 , glyso-a0a445l5n1 , soybn-i1kfz9 , soybn-i1jqs1 , soybn-i1nbc7 , soybn-k7mm57 , soybn-a0a0r0fec7 , soybn-a0a0r0hcn9 , soybn-i1jx17 , soybn-k7kvv2 , soybn-i1kcl6 , soybn-i1kcl7 , soybn-i1jrc3 , soybn-i1nbz1 , soybn-a0a0r0euk2 , soybn-a0a0r0fx16 , soybn-a0a0r0k3t3 , soybn-i1kuc7 , soybn-i1lvy4

Title : Genome, transcriptome, and secretome analysis of wood decay fungus Postia placenta supports unique mechanisms of lignocellulose conversion - Martinez_2009_Proc.Natl.Acad.Sci.U.S.A_106_1954
Author(s) : Martinez D , Challacombe J , Morgenstern I , Hibbett D , Schmoll M , Kubicek CP , Ferreira P , Ruiz-Duenas FJ , Martinez AT , Kersten P , Hammel KE , Vanden Wymelenberg A , Gaskell J , Lindquist E , Sabat G , Bondurant SS , Larrondo LF , Canessa P , Vicuna R , Yadav J , Doddapaneni H , Subramanian V , Pisabarro AG , Lavin JL , Oguiza JA , Master E , Henrissat B , Coutinho PM , Harris P , Magnuson JK , Baker SE , Bruno K , Kenealy W , Hoegger PJ , Kues U , Ramaiya P , Lucas S , Salamov A , Shapiro H , Tu H , Chee CL , Misra M , Xie G , Teter S , Yaver D , James T , Mokrejs M , Pospisek M , Grigoriev IV , Brettin T , Rokhsar D , Berka R , Cullen D
Ref : Proc Natl Acad Sci U S A , 106 :1954 , 2009
Abstract : Brown-rot fungi such as Postia placenta are common inhabitants of forest ecosystems and are also largely responsible for the destructive decay of wooden structures. Rapid depolymerization of cellulose is a distinguishing feature of brown-rot, but the biochemical mechanisms and underlying genetics are poorly understood. Systematic examination of the P. placenta genome, transcriptome, and secretome revealed unique extracellular enzyme systems, including an unusual repertoire of extracellular glycoside hydrolases. Genes encoding exocellobiohydrolases and cellulose-binding domains, typical of cellulolytic microbes, are absent in this efficient cellulose-degrading fungus. When P. placenta was grown in medium containing cellulose as sole carbon source, transcripts corresponding to many hemicellulases and to a single putative beta-1-4 endoglucanase were expressed at high levels relative to glucose-grown cultures. These transcript profiles were confirmed by direct identification of peptides by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Also up-regulated during growth on cellulose medium were putative iron reductases, quinone reductase, and structurally divergent oxidases potentially involved in extracellular generation of Fe(II) and H(2)O(2). These observations are consistent with a biodegradative role for Fenton chemistry in which Fe(II) and H(2)O(2) react to form hydroxyl radicals, highly reactive oxidants capable of depolymerizing cellulose. The P. placenta genome resources provide unparalleled opportunities for investigating such unusual mechanisms of cellulose conversion. More broadly, the genome offers insight into the diversification of lignocellulose degrading mechanisms in fungi. Comparisons with the closely related white-rot fungus Phanerochaete chrysosporium support an evolutionary shift from white-rot to brown-rot during which the capacity for efficient depolymerization of lignin was lost.
ESTHER : Martinez_2009_Proc.Natl.Acad.Sci.U.S.A_106_1954
PubMedSearch : Martinez_2009_Proc.Natl.Acad.Sci.U.S.A_106_1954
PubMedID: 19193860
Gene_locus related to this paper: pospm-b8p1f3 , pospm-b8p2q7 , pospm-b8p4n0 , pospm-b8p4n9 , pospm-b8p5g9 , pospm-b8p5r9 , pospm-b8p6h2 , pospm-b8p7b1 , pospm-b8p7c4 , pospm-b8p8w7 , pospm-b8p9j1 , pospm-b8p164 , pospm-b8p280 , pospm-b8p423.1 , pospm-b8p423.2 , pospm-b8p858 , pospm-b8pam2 , pospm-b8pam5 , pospm-b8pb68 , pospm-b8pbm3 , pospm-b8pc54 , pospm-b8pc56 , pospm-b8pce4 , pospm-b8pd91 , pospm-b8pdk6 , pospm-b8ph32 , pospm-b8ph43 , pospm-b8phc9 , pospm-b8php7 , pospm-b8phy5 , pospm-b8pjg8 , pospm-b8pji9 , pospm-b8plr5 , pospm-b8pmk3 , pospm-b8pfg0 , pospm-b8pg35 , pospm-b8pa20.1 , pospm-b8pa20.2 , pospm-b8p4g8 , pospm-b8phn6

Title : The genome of Nectria haematococca: contribution of supernumerary chromosomes to gene expansion - Coleman_2009_PLoS.Genet_5_e1000618
Author(s) : Coleman JJ , Rounsley SD , Rodriguez-Carres M , Kuo A , Wasmann CC , Grimwood J , Schmutz J , Taga M , White GJ , Zhou S , Schwartz DC , Freitag M , Ma LJ , Danchin EG , Henrissat B , Coutinho PM , Nelson DR , Straney D , Napoli CA , Barker BM , Gribskov M , Rep M , Kroken S , Molnar I , Rensing C , Kennell JC , Zamora J , Farman ML , Selker EU , Salamov A , Shapiro H , Pangilinan J , Lindquist E , Lamers C , Grigoriev IV , Geiser DM , Covert SF , Temporini E , Vanetten HD
Ref : PLoS Genet , 5 :e1000618 , 2009
Abstract : The ascomycetous fungus Nectria haematococca, (asexual name Fusarium solani), is a member of a group of >50 species known as the "Fusarium solani species complex". Members of this complex have diverse biological properties including the ability to cause disease on >100 genera of plants and opportunistic infections in humans. The current research analyzed the most extensively studied member of this complex, N. haematococca mating population VI (MPVI). Several genes controlling the ability of individual isolates of this species to colonize specific habitats are located on supernumerary chromosomes. Optical mapping revealed that the sequenced isolate has 17 chromosomes ranging from 530 kb to 6.52 Mb and that the physical size of the genome, 54.43 Mb, and the number of predicted genes, 15,707, are among the largest reported for ascomycetes. Two classes of genes have contributed to gene expansion: specific genes that are not found in other fungi including its closest sequenced relative, Fusarium graminearum; and genes that commonly occur as single copies in other fungi but are present as multiple copies in N. haematococca MPVI. Some of these additional genes appear to have resulted from gene duplication events, while others may have been acquired through horizontal gene transfer. The supernumerary nature of three chromosomes, 14, 15, and 17, was confirmed by their absence in pulsed field gel electrophoresis experiments of some isolates and by demonstrating that these isolates lacked chromosome-specific sequences found on the ends of these chromosomes. These supernumerary chromosomes contain more repeat sequences, are enriched in unique and duplicated genes, and have a lower G+C content in comparison to the other chromosomes. Although the origin(s) of the extra genes and the supernumerary chromosomes is not known, the gene expansion and its large genome size are consistent with this species' diverse range of habitats. Furthermore, the presence of unique genes on supernumerary chromosomes might account for individual isolates having different environmental niches.
ESTHER : Coleman_2009_PLoS.Genet_5_e1000618
PubMedSearch : Coleman_2009_PLoS.Genet_5_e1000618
PubMedID: 19714214
Gene_locus related to this paper: fusso-cutas , nech7-c7yh18 , nech7-c7yir8 , nech7-c7yiz6 , nech7-c7yjl4 , nech7-c7yjp7 , nech7-c7yjq0 , nech7-c7ymg9 , nech7-c7ymv6 , nech7-c7yna5 , nech7-c7ynt6 , nech7-c7yq59 , nech7-c7yq86 , nech7-c7yqb0 , nech7-c7yqx3 , nech7-c7ysz7 , nech7-c7ysz8 , nech7-c7ytb2 , nech7-c7yum7 , nech7-c7yvb1 , nech7-c7yvb8 , nech7-c7yvf1 , nech7-c7yvq8 , nech7-c7yw21 , nech7-c7yx47 , nech7-c7yx92 , nech7-c7yxe7 , nech7-c7yxq5 , nech7-c7yxz4 , nech7-c7yy47 , nech7-c7yyj7 , nech7-c7yym7 , nech7-c7z0d7 , nech7-c7z0s1 , nech7-c7z1g9 , nech7-c7z1k9 , nech7-c7z2k4 , nech7-c7z2m9 , nech7-c7z2z2 , nech7-c7z3z3 , nech7-c7z4a4 , nech7-c7z5n1 , nech7-c7z5y2 , nech7-c7z6g5 , nech7-c7z7d0 , nech7-c7z7w8 , nech7-c7z8q7 , nech7-c7z9e7 , nech7-c7z073 , nech7-c7z354 , nech7-c7z389 , nech7-c7z688 , nech7-c7z855 , nech7-c7z987 , nech7-c7za94 , nech7-c7zah0 , nech7-c7zb79 , nech7-c7zbr8 , nech7-c7zcd1 , nech7-c7zdx8 , nech7-c7ze42 , nech7-c7ze84 , nech7-c7zed8 , nech7-c7zeh0 , nech7-c7zes2 , nech7-c7zgw2 , nech7-c7zha0 , nech7-c7zhy2 , nech7-c7zi55 , nech7-c7zig4 , nech7-c7zjg0 , nech7-c7zjv2 , nech7-c7zk96 , nech7-c7zkb5 , nech7-c7zkh4 , nech7-c7zla9 , nech7-c7zld2 , nech7-c7zlz1 , nech7-c7zm00 , nech7-c7zmn4 , nech7-c7zmu6 , nech7-c7zp06 , nech7-c7zp78 , nech7-c7zq58 , nech7-c7zq86 , nech7-c7zqb5 , nech7-c7zqk4 , nech7-c7zqp9 , nech7-c7zr59 , nech7-c7zrh2 , nech7-c7zrh3 , nech7-dapb , nech7-kex1 , nech7-c7zgl9 , nech7-c7z935 , nech7-c7znc0 , nech7-c7yiq8 , nech7-c7yiq7 , nech7-c7zhu0 , nech7-c7yw61 , nech7-c7yqd3 , nech7-c7zkb6 , nech7-c7z3b4 , nech7-c7ytr4 , nech7-c7zgf7 , 9hypo-a0a3m2s2j6 , nech7-c7yq54 , fusv7-cbpya

Title : The genome of Laccaria bicolor provides insights into mycorrhizal symbiosis - Martin_2008_Nature_452_88
Author(s) : Martin F , Aerts A , Ahren D , Brun A , Danchin EG , Duchaussoy F , Gibon J , Kohler A , Lindquist E , Pereda V , Salamov A , Shapiro HJ , Wuyts J , Blaudez D , Buee M , Brokstein P , Canback B , Cohen D , Courty PE , Coutinho PM , Delaruelle C , Detter JC , Deveau A , Difazio S , Duplessis S , Fraissinet-Tachet L , Lucic E , Frey-Klett P , Fourrey C , Feussner I , Gay G , Grimwood J , Hoegger PJ , Jain P , Kilaru S , Labbe J , Lin YC , Legue V , Le Tacon F , Marmeisse R , Melayah D , Montanini B , Muratet M , Nehls U , Niculita-Hirzel H , Oudot-Le Secq MP , Peter M , Quesneville H , Rajashekar B , Reich M , Rouhier N , Schmutz J , Yin T , Chalot M , Henrissat B , Kues U , Lucas S , Van de Peer Y , Podila GK , Polle A , Pukkila PJ , Richardson PM , Rouze P , Sanders IR , Stajich JE , Tunlid A , Tuskan G , Grigoriev IV
Ref : Nature , 452 :88 , 2008
Abstract : Mycorrhizal symbioses--the union of roots and soil fungi--are universal in terrestrial ecosystems and may have been fundamental to land colonization by plants. Boreal, temperate and montane forests all depend on ectomycorrhizae. Identification of the primary factors that regulate symbiotic development and metabolic activity will therefore open the door to understanding the role of ectomycorrhizae in plant development and physiology, allowing the full ecological significance of this symbiosis to be explored. Here we report the genome sequence of the ectomycorrhizal basidiomycete Laccaria bicolor (Fig. 1) and highlight gene sets involved in rhizosphere colonization and symbiosis. This 65-megabase genome assembly contains approximately 20,000 predicted protein-encoding genes and a very large number of transposons and repeated sequences. We detected unexpected genomic features, most notably a battery of effector-type small secreted proteins (SSPs) with unknown function, several of which are only expressed in symbiotic tissues. The most highly expressed SSP accumulates in the proliferating hyphae colonizing the host root. The ectomycorrhizae-specific SSPs probably have a decisive role in the establishment of the symbiosis. The unexpected observation that the genome of L. bicolor lacks carbohydrate-active enzymes involved in degradation of plant cell walls, but maintains the ability to degrade non-plant cell wall polysaccharides, reveals the dual saprotrophic and biotrophic lifestyle of the mycorrhizal fungus that enables it to grow within both soil and living plant roots. The predicted gene inventory of the L. bicolor genome, therefore, points to previously unknown mechanisms of symbiosis operating in biotrophic mycorrhizal fungi. The availability of this genome provides an unparalleled opportunity to develop a deeper understanding of the processes by which symbionts interact with plants within their ecosystem to perform vital functions in the carbon and nitrogen cycles that are fundamental to sustainable plant productivity.
ESTHER : Martin_2008_Nature_452_88
PubMedSearch : Martin_2008_Nature_452_88
PubMedID: 18322534
Gene_locus related to this paper: lacbs-b0cns1 , lacbs-b0cpl4 , lacbs-b0cr62 , lacbs-b0cr66 , lacbs-b0csq9 , lacbs-b0ct56 , lacbs-b0ctt5 , lacbs-b0cuw1 , lacbs-b0cv23 , lacbs-b0cxm7 , lacbs-b0cz37 , lacbs-b0czx3 , lacbs-b0d0z5 , lacbs-b0d4i0 , lacbs-b0d4j3 , lacbs-b0d5n6 , lacbs-b0d8k0 , lacbs-b0d263 , lacbs-b0dhh1 , lacbs-b0dkp6 , lacbs-b0dmr2 , lacbs-b0dmt4 , lacbs-b0dsx5 , lacbs-b0dt05 , lacbs-b0dtw4 , lacbs-b0du88 , lacbs-b0dsl6

Title : The Phaeodactylum genome reveals the evolutionary history of diatom genomes - Bowler_2008_Nature_456_239
Author(s) : Bowler C , Allen AE , Badger JH , Grimwood J , Jabbari K , Kuo A , Maheswari U , Martens C , Maumus F , Otillar RP , Rayko E , Salamov A , Vandepoele K , Beszteri B , Gruber A , Heijde M , Katinka M , Mock T , Valentin K , Verret F , Berges JA , Brownlee C , Cadoret JP , Chiovitti A , Choi CJ , Coesel S , De Martino A , Detter JC , Durkin C , Falciatore A , Fournet J , Haruta M , Huysman MJ , Jenkins BD , Jiroutova K , Jorgensen RE , Joubert Y , Kaplan A , Kroger N , Kroth PG , La Roche J , Lindquist E , Lommer M , Martin-Jezequel V , Lopez PJ , Lucas S , Mangogna M , McGinnis K , Medlin LK , Montsant A , Oudot-Le Secq MP , Napoli C , Obornik M , Parker MS , Petit JL , Porcel BM , Poulsen N , Robison M , Rychlewski L , Rynearson TA , Schmutz J , Shapiro H , Siaut M , Stanley M , Sussman MR , Taylor AR , Vardi A , von Dassow P , Vyverman W , Willis A , Wyrwicz LS , Rokhsar DS , Weissenbach J , Armbrust EV , Green BR , Van de Peer Y , Grigoriev IV
Ref : Nature , 456 :239 , 2008
Abstract : Diatoms are photosynthetic secondary endosymbionts found throughout marine and freshwater environments, and are believed to be responsible for around one-fifth of the primary productivity on Earth. The genome sequence of the marine centric diatom Thalassiosira pseudonana was recently reported, revealing a wealth of information about diatom biology. Here we report the complete genome sequence of the pennate diatom Phaeodactylum tricornutum and compare it with that of T. pseudonana to clarify evolutionary origins, functional significance and ubiquity of these features throughout diatoms. In spite of the fact that the pennate and centric lineages have only been diverging for 90 million years, their genome structures are dramatically different and a substantial fraction of genes ( approximately 40%) are not shared by these representatives of the two lineages. Analysis of molecular divergence compared with yeasts and metazoans reveals rapid rates of gene diversification in diatoms. Contributing factors include selective gene family expansions, differential losses and gains of genes and introns, and differential mobilization of transposable elements. Most significantly, we document the presence of hundreds of genes from bacteria. More than 300 of these gene transfers are found in both diatoms, attesting to their ancient origins, and many are likely to provide novel possibilities for metabolite management and for perception of environmental signals. These findings go a long way towards explaining the incredible diversity and success of the diatoms in contemporary oceans.
ESTHER : Bowler_2008_Nature_456_239
PubMedSearch : Bowler_2008_Nature_456_239
PubMedID: 18923393
Gene_locus related to this paper: phatc-b7fp91 , phatc-b7fqd3 , phatc-b7frf9 , phatc-b7fry8 , phatc-b7ftw8 , phatc-b7fv70 , phatc-b7fw66 , phatc-b7g2b2 , phatc-b7g5z5 , phatc-b7g6f1 , phatc-b7g6r8 , phatc-b7g957 , phatc-b7ga73 , phatc-b7gb22 , phatc-b7gc60 , phatc-b7gdm3 , phatc-b7gdq6 , phatc-b7ge82 , phatc-b7gee0 , phatr-b7frs5 , phatr-b7g1k3 , phatr-b7s4a4 , thaps-b8bsy4 , thaps-b8cfn8 , phatc-b7g635 , phatc-b7gaj3 , thaps-b8c079

Title : The amphioxus genome and the evolution of the chordate karyotype - Putnam_2008_Nature_453_1064
Author(s) : Putnam NH , Butts T , Ferrier DE , Furlong RF , Hellsten U , Kawashima T , Robinson-Rechavi M , Shoguchi E , Terry A , Yu JK , Benito-Gutierrez EL , Dubchak I , Garcia-Fernandez J , Gibson-Brown JJ , Grigoriev IV , Horton AC , de Jong PJ , Jurka J , Kapitonov VV , Kohara Y , Kuroki Y , Lindquist E , Lucas S , Osoegawa K , Pennacchio LA , Salamov AA , Satou Y , Sauka-Spengler T , Schmutz J , Shin IT , Toyoda A , Bronner-Fraser M , Fujiyama A , Holland LZ , Holland PW , Satoh N , Rokhsar DS
Ref : Nature , 453 :1064 , 2008
Abstract : Lancelets ('amphioxus') are the modern survivors of an ancient chordate lineage, with a fossil record dating back to the Cambrian period. Here we describe the structure and gene content of the highly polymorphic approximately 520-megabase genome of the Florida lancelet Branchiostoma floridae, and analyse it in the context of chordate evolution. Whole-genome comparisons illuminate the murky relationships among the three chordate groups (tunicates, lancelets and vertebrates), and allow not only reconstruction of the gene complement of the last common chordate ancestor but also partial reconstruction of its genomic organization, as well as a description of two genome-wide duplications and subsequent reorganizations in the vertebrate lineage. These genome-scale events shaped the vertebrate genome and provided additional genetic variation for exploitation during vertebrate evolution.
ESTHER : Putnam_2008_Nature_453_1064
PubMedSearch : Putnam_2008_Nature_453_1064
PubMedID: 18563158
Gene_locus related to this paper: brafl-ACHE1 , brafl-ACHE2 , brafl-ACHEA , brafl-ACHEB , brafl-c3xqm2 , brafl-c3xqm5 , brafl-c3xtl0 , brafl-c3xtl1 , brafl-c3xut6 , brafl-c3xut7 , brafl-c3xvw5 , brafl-c3xx27 , brafl-c3xx28 , brafl-c3xx30 , brafl-c3xx32 , brafl-c3xx36 , brafl-c3xx38 , brafl-c3xx39 , brafl-c3xx40 , brafl-c3xx41 , brafl-c3xxt9 , brafl-c3xyd7 , brafl-c3xyd8 , brafl-c3xyd9 , brafl-c3xye0 , brafl-c3xyt7 , brafl-c3xzy1 , brafl-c3xzy2 , brafl-c3y1p9 , brafl-c3y1t3 , brafl-c3y2u3 , brafl-c3y4l1 , brafl-c3y6v9 , brafl-c3y6y4 , brafl-c3y7d7 , brafl-c3y7s1 , brafl-c3y8k5 , brafl-c3y8t3 , brafl-c3y8t4 , brafl-c3y8t5 , brafl-c3y8v8 , brafl-c3y8w1.1 , brafl-c3y8w2 , brafl-c3y9i7 , brafl-c3y9i8 , brafl-c3y9l9 , brafl-c3y9y3 , brafl-c3y087 , brafl-c3yan2 , brafl-c3yaw4 , brafl-c3ybw7 , brafl-c3yc67 , brafl-c3ydm8 , brafl-c3yfm5 , brafl-c3yfz8 , brafl-c3ygc7 , brafl-c3ygc9.1 , brafl-c3ygd0 , brafl-c3ygd1 , brafl-c3ygd2.1 , brafl-c3ygd4 , brafl-c3ygg6 , brafl-c3ygr1 , brafl-c3yi63 , brafl-c3yi64 , brafl-c3yi67 , brafl-c3yi68 , brafl-c3yi69 , brafl-c3yk61 , brafl-c3ykb2 , brafl-c3yla7 , brafl-c3ylp9 , brafl-c3ylq0 , brafl-c3ylq1 , brafl-c3ymu0 , brafl-c3yne9 , brafl-c3ypm6 , brafl-c3yr72 , brafl-c3yra8 , brafl-c3ys59 , brafl-c3yv27 , brafl-c3ywf1 , brafl-c3ywh9 , brafl-c3yx17 , brafl-c3yx19 , brafl-c3yxb9 , brafl-c3yxi7 , brafl-c3yyq5 , brafl-c3yz04 , brafl-c3z1c7 , brafl-c3z1u9 , brafl-c3z1v0 , brafl-c3z3n7 , brafl-c3z5c8 , brafl-c3z9f4 , brafl-c3z066 , brafl-c3z139 , brafl-c3z975 , brafl-c3zab8 , brafl-c3zab9 , brafl-c3zbr4 , brafl-c3zci7 , brafl-c3zcy8 , brafl-c3zd14 , brafl-c3zer1 , brafl-c3zf44 , brafl-c3zf47 , brafl-c3zf48 , brafl-c3zfs6 , brafl-c3zhm6 , brafl-c3ziv7.1 , brafl-c3ziv7.2 , brafl-c3zlg0 , brafl-c3zlg2 , brafl-c3zlg3 , brafl-c3zli5 , brafl-c3zme7 , brafl-c3zme8 , brafl-c3zmp8 , brafl-c3zmv1 , brafl-c3zmv2 , brafl-c3znd6 , brafl-c3znl2 , brafl-c3zqg7 , brafl-c3zqz2 , brafl-c3zs46 , brafl-c3zs49 , brafl-c3zs56 , brafl-c3zv54 , brafl-c3zvv1 , brafl-c3zwz6 , brafl-c3zxg2 , brafl-c3zxq3 , brafl-c3yim2 , brafl-c3zfs5 , brafl-c3zfs3 , brafl-c3xr79 , brafl-c3y7r2 , brafl-c3yj62 , brafl-c3zg22 , brafl-c3y2t9 , brafl-c3y2u0 , brafl-c3ycg1 , brafl-c3ycg2 , brafl-c3ycg4 , brafl-c3z1l3 , brafl-c3zn71 , brafl-c3zj72 , brafl-c3yf35 , brafl-c3z474 , brafl-c3zqr8 , brafl-c3yde6

Title : The Chlamydomonas genome reveals the evolution of key animal and plant functions - Merchant_2007_Science_318_245
Author(s) : Merchant SS , Prochnik SE , Vallon O , Harris EH , Karpowicz SJ , Witman GB , Terry A , Salamov A , Fritz-Laylin LK , Marechal-Drouard L , Marshall WF , Qu LH , Nelson DR , Sanderfoot AA , Spalding MH , Kapitonov VV , Ren Q , Ferris P , Lindquist E , Shapiro H , Lucas SM , Grimwood J , Schmutz J , Cardol P , Cerutti H , Chanfreau G , Chen CL , Cognat V , Croft MT , Dent R , Dutcher S , Fernandez E , Fukuzawa H , Gonzalez-Ballester D , Gonzalez-Halphen D , Hallmann A , Hanikenne M , Hippler M , Inwood W , Jabbari K , Kalanon M , Kuras R , Lefebvre PA , Lemaire SD , Lobanov AV , Lohr M , Manuell A , Meier I , Mets L , Mittag M , Mittelmeier T , Moroney JV , Moseley J , Napoli C , Nedelcu AM , Niyogi K , Novoselov SV , Paulsen IT , Pazour G , Purton S , Ral JP , Riano-Pachon DM , Riekhof W , Rymarquis L , Schroda M , Stern D , Umen J , Willows R , Wilson N , Zimmer SL , Allmer J , Balk J , Bisova K , Chen CJ , Elias M , Gendler K , Hauser C , Lamb MR , Ledford H , Long JC , Minagawa J , Page MD , Pan J , Pootakham W , Roje S , Rose A , Stahlberg E , Terauchi AM , Yang P , Ball S , Bowler C , Dieckmann CL , Gladyshev VN , Green P , Jorgensen R , Mayfield S , Mueller-Roeber B , Rajamani S , Sayre RT , Brokstein P , Dubchak I , Goodstein D , Hornick L , Huang YW , Jhaveri J , Luo Y , Martinez D , Ngau WC , Otillar B , Poliakov A , Porter A , Szajkowski L , Werner G , Zhou K , Grigoriev IV , Rokhsar DS , Grossman AR
Ref : Science , 318 :245 , 2007
Abstract : Chlamydomonas reinhardtii is a unicellular green alga whose lineage diverged from land plants over 1 billion years ago. It is a model system for studying chloroplast-based photosynthesis, as well as the structure, assembly, and function of eukaryotic flagella (cilia), which were inherited from the common ancestor of plants and animals, but lost in land plants. We sequenced the approximately 120-megabase nuclear genome of Chlamydomonas and performed comparative phylogenomic analyses, identifying genes encoding uncharacterized proteins that are likely associated with the function and biogenesis of chloroplasts or eukaryotic flagella. Analyses of the Chlamydomonas genome advance our understanding of the ancestral eukaryotic cell, reveal previously unknown genes associated with photosynthetic and flagellar functions, and establish links between ciliopathy and the composition and function of flagella.
ESTHER : Merchant_2007_Science_318_245
PubMedSearch : Merchant_2007_Science_318_245
PubMedID: 17932292
Gene_locus related to this paper: chlre-a0a2k3e2k6 , chlre-a8hmd4 , chlre-a8hqa9 , chlre-a8htq0 , chlre-a8hus6.1 , chlre-a8hus6.2 , chlre-a8icg4 , chlre-a8iwm0 , chlre-a8ize5 , chlre-a8j2s9 , chlre-a8j5w6 , chlre-a8j7f8 , chlre-a8j8u9 , chlre-a8j8v0 , chlre-a8j9u6 , chlre-a8j143 , chlre-a8j248 , chlre-a8jd32 , chlre-a8jd42 , chlre-a8jgj2 , chlre-a8jhc8 , chlre-a8jhe5 , chlre-a8iwj1 , chlre-a8j7d5 , chlre-a0a2k3dii0

Title : Sea anemone genome reveals ancestral eumetazoan gene repertoire and genomic organization - Putnam_2007_Science_317_86
Author(s) : Putnam NH , Srivastava M , Hellsten U , Dirks B , Chapman J , Salamov A , Terry A , Shapiro H , Lindquist E , Kapitonov VV , Jurka J , Genikhovich G , Grigoriev IV , Lucas SM , Steele RE , Finnerty JR , Technau U , Martindale MQ , Rokhsar DS
Ref : Science , 317 :86 , 2007
Abstract : Sea anemones are seemingly primitive animals that, along with corals, jellyfish, and hydras, constitute the oldest eumetazoan phylum, the Cnidaria. Here, we report a comparative analysis of the draft genome of an emerging cnidarian model, the starlet sea anemone Nematostella vectensis. The sea anemone genome is complex, with a gene repertoire, exon-intron structure, and large-scale gene linkage more similar to vertebrates than to flies or nematodes, implying that the genome of the eumetazoan ancestor was similarly complex. Nearly one-fifth of the inferred genes of the ancestor are eumetazoan novelties, which are enriched for animal functions like cell signaling, adhesion, and synaptic transmission. Analysis of diverse pathways suggests that these gene "inventions" along the lineage leading to animals were likely already well integrated with preexisting eukaryotic genes in the eumetazoan progenitor.
ESTHER : Putnam_2007_Science_317_86
PubMedSearch : Putnam_2007_Science_317_86
PubMedID: 17615350
Gene_locus related to this paper: nemve-a7rfc6 , nemve-a7rhs0 , nemve-a7rhw2 , nemve-a7ric9 , nemve-a7riu9 , nemve-a7rk54 , nemve-a7rlg8 , nemve-a7rlv4 , nemve-a7rn07 , nemve-a7rn08 , nemve-a7rn68 , nemve-a7rnv3 , nemve-a7rpb3 , nemve-a7rpq4 , nemve-a7rqa8 , nemve-a7rqw3 , nemve-a7rwv1 , nemve-a7rxl6 , nemve-a7s1d5 , nemve-a7s3l3 , nemve-a7s3q1 , nemve-a7s5u3 , nemve-a7s6g4 , nemve-a7s6s7 , nemve-a7sa46 , nemve-a7sbd9 , nemve-a7sbe0 , nemve-a7sbm6 , nemve-a7scy7 , nemve-a7sex0 , nemve-a7sfa0 , nemve-a7sff3 , nemve-a7sgb1 , nemve-a7shf2 , nemve-a7siv4 , nemve-a7sj77 , nemve-a7sjw1 , nemve-a7skr3 , nemve-a7slm1 , nemve-a7slm2 , nemve-a7sp35 , nemve-a7sq47 , nemve-a7sq73 , nemve-a7sqk0 , nemve-a7su21 , nemve-a7su25 , nemve-a7svn0 , nemve-a7svu2 , nemve-a7sx21 , nemve-a7syk4 , nemve-a7t3e6 , nemve-a7suy2 , nemve-a7s803 , nemve-a7t3m9 , nemve-a0a1t4jh34 , nemve-a7rvd5 , nemve-a7rhu9 , nemve-a7si15

Title : Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis - Jeffries_2007_Nat.Biotechnol_25_319
Author(s) : Jeffries TW , Grigoriev IV , Grimwood J , Laplaza JM , Aerts A , Salamov A , Schmutz J , Lindquist E , Dehal P , Shapiro H , Jin YS , Passoth V , Richardson PM
Ref : Nat Biotechnol , 25 :319 , 2007
Abstract : Xylose is a major constituent of plant lignocellulose, and its fermentation is important for the bioconversion of plant biomass to fuels and chemicals. Pichia stipitis is a well-studied, native xylose-fermenting yeast. The mechanism and regulation of xylose metabolism in P. stipitis have been characterized and genes from P. stipitis have been used to engineer xylose metabolism in Saccharomyces cerevisiae. We have sequenced and assembled the complete genome of P. stipitis. The sequence data have revealed unusual aspects of genome organization, numerous genes for bioconversion, a preliminary insight into regulation of central metabolic pathways and several examples of colocalized genes with related functions. The genome sequence provides insight into how P. stipitis regulates its redox balance while very efficiently fermenting xylose under microaerobic conditions.
ESTHER : Jeffries_2007_Nat.Biotechnol_25_319
PubMedSearch : Jeffries_2007_Nat.Biotechnol_25_319
PubMedID: 17334359
Gene_locus related to this paper: picst-a3geu9 , picst-a3gfu2 , picst-a3ggh9 , picst-a3gha8 , picst-a3ghe3 , picst-a3gi73 , picst-a3lmu3 , picst-a3ln06 , picst-a3ln59 , picst-a3lnv8 , picst-a3lp77 , picst-a3lqt4 , picst-a3lrt0 , picst-a3ls15 , picst-a3lsj8 , picst-a3lu11 , picst-a3luu0 , picst-a3lv87 , picst-a3lvi5 , picst-a3lvu9 , picst-a3lvv2 , picst-a3lwa4 , picst-a3lxl2 , picst-a3lxs8 , picst-a3lyi3 , picst-atg15 , picst-bna7 , picst-a3lyh1 , picst-a3lnc5 , picst-a3lr32