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Paper Report for: Biftu_2007_Bioorg.Med.Chem.Lett_17_3384

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Title: Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin
Biftu T, Scapin G, Singh S, Feng D, Becker JW, Eiermann G, He H, Lyons K, Patel S and Weber AE <7 more author(s)>
Ref: Bioorganic & Medicinal Chemistry Lett, 17:3384, 2007 : PubMed

        



Related information

Gene_Locus| human-DPP4
Structure in RCSB-PDB | 2P8S
Structure in ESTHER | 2P8S
Inhibitor | CHEMBL233360, Sitagliptin,


Citations formats

Biftu T, Scapin G, Singh S, Feng D, Becker JW, Eiermann G, He H, Lyons K, Patel S, Petrov A, Sinha-Roy R, Zhang B, Wu J, Zhang X, Doss GA, Thornberry NA, Weber AE (2007)
Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin
Bioorganic & Medicinal Chemistry Lett 17: 3384-7

Biftu T, Scapin G, Singh S, Feng D, Becker JW, Eiermann G, He H, Lyons K, Patel S, Petrov A, Sinha-Roy R, Zhang B, Wu J, Zhang X, Doss GA, Thornberry NA, Weber AE (2007)
Bioorganic & Medicinal Chemistry Lett 17: 3384-7



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