Name : Prolyl Oligopeptidase from porcine brain with a covalently bound P2- substituted N-acyl-prolylpyrrolidine inhibitor 1

Revelation date : 13-Mar-2013

Family : S9N_PPCE_Peptidase_S9

Gene_locus : pig-ppce

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Van Der Veken, P., Fulop, V., Rea, D., Gerard, M., VanElzen, R., Joossens, J., Cheng, J.D., Baekelandt, V., DeMeester, I., Lambeir, A.M., Augustyns, K.

Ligand : Inhibitor N-acyl-prolylpyrrolidine-inhibitor-1 Ligand in structure: Ligplot

References (1)

Title : P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy - Van der Veken_2012_J.Med.Chem_55_9856
Author(s) : Van der Veken P , Fulop V , Rea D , Gerard M , Van Elzen R , Joossens J , Cheng JD , Baekelandt V , De Meester I , Lambeir AM , Augustyns K
Ref : Journal of Medicinal Chemistry , 55 :9856 , 2012
Abstract :
PubMedSearch : Van der Veken_2012_J.Med.Chem_55_9856
PubMedID: 23121075
Gene_locus related to this paper: pig-ppce

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server


PDB-Sum : 4BCB Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 4BCB Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 4BCB Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 4BCB 3D, interactive encyclopedia of proteins - PROTEOPEDIA server