| Title : Extended structure-activity relationship and pharmacokinetic investigation of (4-quinolinoyl)glycyl-2-cyanopyrrolidine inhibitors of fibroblast activation protein (FAP) - Jansen_2014_J.Med.Chem_57_3053 |
| Author(s) : Jansen K , Heirbaut L , Verkerk R , Cheng JD , Joossens J , Cos P , Maes L , Lambeir AM , De Meester I , Augustyns K , Van der Veken P |
| Ref : Journal of Medicinal Chemistry , 57 :3053 , 2014 |
| Abstract : |
| PubMedSearch : Jansen_2014_J.Med.Chem_57_3053 |
| PubMedID: 24617858 |
| Title : Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold - Jansen_2013_ACS.Med.Chem.Lett_4_491 |
| Author(s) : Jansen K , Heirbaut L , Cheng JD , Joossens J , Ryabtsova O , Cos P , Maes L , Lambeir AM , De Meester I , Augustyns K , Van der Veken P |
| Ref : ACS Med Chem Lett , 4 :491 , 2013 |
| Abstract : |
| PubMedSearch : Jansen_2013_ACS.Med.Chem.Lett_4_491 |
| PubMedID: 24900696 |
| Title : P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy - Van der Veken_2012_J.Med.Chem_55_9856 |
| Author(s) : Van der Veken P , Fulop V , Rea D , Gerard M , Van Elzen R , Joossens J , Cheng JD , Baekelandt V , De Meester I , Lambeir AM , Augustyns K |
| Ref : Journal of Medicinal Chemistry , 55 :9856 , 2012 |
| Abstract : |
| PubMedSearch : Van der Veken_2012_J.Med.Chem_55_9856 |
| PubMedID: 23121075 |
| Gene_locus related to this paper: pig-ppce |
| Title : Acylated Gly-(2-cyano)pyrrolidines as inhibitors of fibroblast activation protein (FAP) and the issue of FAP\/prolyl oligopeptidase (PREP)-selectivity - Ryabtsova_2012_Bioorg.Med.Chem.Lett_22_3412 |
| Author(s) : Ryabtsova O , Jansen K , Van Goethem S , Joossens J , Cheng JD , Lambeir AM , De Meester I , Augustyns K , Van der Veken P |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :3412 , 2012 |
| Abstract : |
| PubMedSearch : Ryabtsova_2012_Bioorg.Med.Chem.Lett_22_3412 |
| PubMedID: 22525314 |
| Title : Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal? - Van Goethem_2011_J.Med.Chem_54_5737 |
| Author(s) : Van Goethem S , Matheeussen V , Joossens J , Lambeir AM , Chen X , De Meester I , Haemers A , Augustyns K , Van der Veken P |
| Ref : Journal of Medicinal Chemistry , 54 :5737 , 2011 |
| Abstract : |
| PubMedSearch : Van Goethem_2011_J.Med.Chem_54_5737 |
| PubMedID: 21711053 |
| Gene_locus related to this paper: human-DPP8 , human-DPP9 |
| Title : Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile) - Brandt_2005_Biochem.Pharmacol_70_134 |
| Author(s) : Brandt I , Joossens J , Chen X , Maes MB , Scharpe S , De Meester I , Lambeir AM |
| Ref : Biochemical Pharmacology , 70 :134 , 2005 |
| Abstract : |
| PubMedSearch : Brandt_2005_Biochem.Pharmacol_70_134 |
| PubMedID: 15907807 |