| Title : Extended structure-activity relationship and pharmacokinetic investigation of (4-quinolinoyl)glycyl-2-cyanopyrrolidine inhibitors of fibroblast activation protein (FAP) - Jansen_2014_J.Med.Chem_57_3053 |
| Author(s) : Jansen K , Heirbaut L , Verkerk R , Cheng JD , Joossens J , Cos P , Maes L , Lambeir AM , De Meester I , Augustyns K , Van der Veken P |
| Ref : Journal of Medicinal Chemistry , 57 :3053 , 2014 |
| Abstract : |
| PubMedSearch : Jansen_2014_J.Med.Chem_57_3053 |
| PubMedID: 24617858 |
| Gene_locus related to this paper: human-FAP |
| Title : Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold - Jansen_2013_ACS.Med.Chem.Lett_4_491 |
| Author(s) : Jansen K , Heirbaut L , Cheng JD , Joossens J , Ryabtsova O , Cos P , Maes L , Lambeir AM , De Meester I , Augustyns K , Van der Veken P |
| Ref : ACS Med Chem Lett , 4 :491 , 2013 |
| Abstract : |
| PubMedSearch : Jansen_2013_ACS.Med.Chem.Lett_4_491 |
| PubMedID: 24900696 |
| Gene_locus related to this paper: human-FAP |
| Title : Acylated Gly-(2-cyano)pyrrolidines as inhibitors of fibroblast activation protein (FAP) and the issue of FAP\/prolyl oligopeptidase (PREP)-selectivity - Ryabtsova_2012_Bioorg.Med.Chem.Lett_22_3412 |
| Author(s) : Ryabtsova O , Jansen K , Van Goethem S , Joossens J , Cheng JD , Lambeir AM , De Meester I , Augustyns K , Van der Veken P |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :3412 , 2012 |
| Abstract : |
| PubMedSearch : Ryabtsova_2012_Bioorg.Med.Chem.Lett_22_3412 |
| PubMedID: 22525314 |
| Gene_locus related to this paper: human-FAP |
| Title : P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy - Van der Veken_2012_J.Med.Chem_55_9856 |
| Author(s) : Van der Veken P , Fulop V , Rea D , Gerard M , Van Elzen R , Joossens J , Cheng JD , Baekelandt V , De Meester I , Lambeir AM , Augustyns K |
| Ref : Journal of Medicinal Chemistry , 55 :9856 , 2012 |
| Abstract : |
| PubMedSearch : Van der Veken_2012_J.Med.Chem_55_9856 |
| PubMedID: 23121075 |
| Gene_locus related to this paper: pig-ppce |
| Title : Selective fluorescence probes for dipeptidyl peptidase activity-fibroblast activation protein and dipeptidyl peptidase IV - Lai_2007_Bioconjug.Chem_18_1246 |
| Author(s) : Lai KS , Ho NH , Cheng JD , Tung CH |
| Ref : Bioconjug Chem , 18 :1246 , 2007 |
| Abstract : |
| PubMedSearch : Lai_2007_Bioconjug.Chem_18_1246 |
| PubMedID: 17489551 |
| Title : Phase II trial of single agent Val-boroPro (Talabostat) inhibiting Fibroblast Activation Protein in patients with metastatic colorectal cancer - Narra_2007_Cancer.Biol.Ther_6_1691 |
| Author(s) : Narra K , Mullins SR , Lee HO , Strzemkowski-Brun B , Magalong K , Christiansen VJ , McKee PA , Egleston B , Cohen SJ , Weiner LM , Meropol NJ , Cheng JD |
| Ref : Cancer Biol Ther , 6 :1691 , 2007 |
| Abstract : |
| PubMedSearch : Narra_2007_Cancer.Biol.Ther_6_1691 |
| PubMedID: 18032930 |
| Title : Dipeptidyl peptidase 8\/9-like activity in human leukocytes - Maes_2007_J.Leukoc.Biol_81_1252 |
| Author(s) : Maes MB , Dubois V , Brandt I , Lambeir AM , Van der Veken P , Augustyns K , Cheng JD , Chen X , Scharpe S , De Meester I |
| Ref : J Leukoc Biol , 81 :1252 , 2007 |
| Abstract : |
| PubMedSearch : Maes_2007_J.Leukoc.Biol_81_1252 |
| PubMedID: 17287297 |