5V40

Name : Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor TAM6

Revelation date : 05-Jul-2017

Family : Thioesterase

Gene_locus : myctu-PKS13

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Aggarwal, A., Sacchettini, J.C. (5F4G withdrawn)

Ligand :

References (1)

Title : Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13 - Aggarwal_2017_Cell_170_249
Author(s) : Aggarwal A , Parai MK , Shetty N , Wallis D , Woolhiser L , Hastings C , Dutta NK , Galaviz S , Dhakal RC , Shrestha R , Wakabayashi S , Walpole C , Matthews D , Floyd D , Scullion P , Riley J , Epemolu O , Norval S , Snavely T , Robertson GT , Rubin EJ , Ioerger TR , Sirgel FA , van der Merwe R , van Helden PD , Keller P , Bottger EC , Karakousis PC , Lenaerts AJ , Sacchettini JC
Ref : Cell , 170 :249 , 2017
PubMedID: 28669536
Gene_locus related to this paper: myctu-PKS13

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 5V40 Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 5V40 Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 5V40 Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 5V40 3D, interactive encyclopedia of proteins - PROTEOPEDIA server