6FLD

Name : Carbamylated Torpedo californica acetylcholineterase bound to uncharged hybrid reactivator Tacrine-pyridinealdoxime-1

Revelation date : 29-Aug-2018

Family : ACHE

Gene_locus : torca-ACHE

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
De la Mora, E., Santoni, G., de Souza, J., Sussman, J., Silman, I., Baati, R., Weik, M., Nachon, F.

Ligand : Ligand in structure: Ligplot

References (1)

Title : Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents - Santoni_2018_J.Med.Chem_61_7630
Author(s) : Santoni G , de Sousa J , De la Mora E , Dias J , Jean L , Sussman JL , Silman I , Renard PY , Brown RCD , Weik M , Baati R , Nachon F
Ref : Journal of Medicinal Chemistry , 61 :7630 , 2018
Abstract :
PubMedSearch : Santoni_2018_J.Med.Chem_61_7630
PubMedID: 30125110
Gene_locus related to this paper: torca-ACHE

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 6FLD Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 6FLD Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 6FLD Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 6FLD 3D, interactive encyclopedia of proteins - PROTEOPEDIA server