7B8D

Name : Structure of the human Wnt deacylase Notum in complex with (fragment 151) Sulfapyridine

Revelation date : 12-Jan-2022

Family : Pectinacetylesterase-Notum

Gene_locus : human-NOTUM

PDB file : ESTHER: header of PDB entry RCSB: Full entry

Comment
Zhao, Y.,Jones, E.Y.

Ligand : Inhibitor Sulfapyridine Ligand in structure: Ligplot

References (1)

Title : Structural Analysis and Development of Notum Fragment Screening Hits - Zhao_2022_ACS.Chem.Neurosci_13_2060
Author(s) : Zhao Y , Mahy W , Willis NJ , Woodward HL , Steadman D , Bayle ED , Atkinson BN , Sipthorp J , Vecchia L , Ruza RR , Harlos K , Jeganathan F , Constantinou S , Costa A , Kjaer S , Bictash M , Salinas PC , Whiting P , Vincent JP , Fish PV , Jones EY
Ref : ACS Chem Neurosci , 13 :2060 , 2022
Abstract :
PubMedSearch : Zhao_2022_ACS.Chem.Neurosci_13_2060
PubMedID: 35731924
Gene_locus related to this paper: human-NOTUM

Representative scheme of Prolylcarboxypeptidase structure and an image from PDBsum server

Databases

PDB-Sum : 7B8D Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server

FSSP : 7B8D Fold classification based on Structure-Structure alignment of Proteins - FSSP server

SCOP : 7B8D Structural Classification Of Protein - SCOP server

PROTEOPEDIA : 7B8D 3D, interactive encyclopedia of proteins - PROTEOPEDIA server