Structure

Tree Display

AceDB Schema

XML Display

Feedback

Structure Report for: 6AUM

Name|Crystal structure of human soluble epoxide hydrolase complexed with trans-4-[4-(3-trifluoromethoxyphenyl-l-ureido)-cyclohexyloxy]-benzoic acid
Revelation date|07-Feb-2018
Family|Epoxide_hydrolase: there are 1166 genes in this family, 168 structure(s)
Gene_locus|human-EPHX2
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Kodani, S.D., Bahkta, S., Hwang, S.H., Pakhomova, S., Newcomer, M.E., Morisseau, C., Hammock, B.
Ligand|Inhibitor: t-TUCB Ligand in structure: Ligplot


Reference

    Title: Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase
    Kodani SD, Bhakta S, Hwang SH, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD
    Ref: Bioorganic & Medicinal Chemistry Lett, 28:762, 2018 : PubMed

            



Representative scheme of Epoxide_hydrolase structure and an image from PDBsum server

no Image


Databases

PDB-Sum6AUM Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6AUM Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6AUM Structural Classification Of Protein - SCOP server
PROTEOPEDIA6aum 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
webmaster

Acknowledgements and disclaimer