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Structure Report for: 6AUM

Name|Crystal structure of human soluble epoxide hydrolase complexed with trans-4-[4-(3-trifluoromethoxyphenyl-l-ureido)-cyclohexyloxy]-benzoic acid
Revelation date|07-Feb-2018
Family|Epoxide_hydrolase: there are 1166 genes in this family, 168 structure(s)
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Kodani, S.D., Bahkta, S., Hwang, S.H., Pakhomova, S., Newcomer, M.E., Morisseau, C., Hammock, B.
Ligand|Inhibitor: t-TUCB Ligand in structure: Ligplot


    Title: Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase
    Kodani SD, Bhakta S, Hwang SH, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD
    Ref: Bioorganic & Medicinal Chemistry Lett, 28:762, 2018 : PubMed


Representative scheme of Epoxide_hydrolase structure and an image from PDBsum server

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PDB-Sum6AUM Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP6AUM Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP6AUM Structural Classification Of Protein - SCOP server
PROTEOPEDIA6aum 3D, interactive encyclopedia of proteins - PROTEOPEDIA server

Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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