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Structure Report for: 7ZXS

Name|Crystal structure of DPP9 in complex with a 4-oxo-b-lactam based inhibitor, A295
Revelation date|28-Sep-2022
Family|DPP4N_Peptidase_S9: there are 829 genes in this family, 182 structure(s)
Gene_locus|human-DPP9
PDB File|ESTHER: header of PDB entry RCSB: Full entry
Comment|
Ross, B.,Huber, R.
Ligand|Inhibitor: beta-lactam-A295 Ligand in structure: Ligplot


Reference

    Title: Chemoproteomics-Enabled Identification of 4-Oxo-beta-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9
    Carvalho LAR, Ross B, Fehr L, Bolgi O, Wohrle S, Lum KM, Podlesainski D, Vieira AC, Kiefersauer R and Moreira R <8 more author(s)>
    Ref: Angew Chem Int Ed Engl, :, 2022 : PubMed

            



Representative scheme of DPP4N_Peptidase_S9 structure and an image from PDBsum server

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Databases

PDB-Sum7ZXS Previously Class, Architecture, Topology and Homologous superfamily - PDB-Sum server
FSSP7ZXS Fold classification based on Structure-Structure alignment of Proteins - FSSP server
SCOP7ZXS Structural Classification Of Protein - SCOP server
PROTEOPEDIA7zxs 3D, interactive encyclopedia of proteins - PROTEOPEDIA server



Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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