3-Acetoxyindole

indoxyl acetate is cleaved to indoxyl and acetate moiety and blue indigo is created

General

Type : Acetate, Indole, Fluorescent Probe

Chemical_Nomenclature : 1H-indol-3-yl acetate

Canonical SMILES : CC(=O)OC1=CNC2=CC=CC=C21

InChI : InChI=1S\/C10H9NO2\/c1-7(12)13-10-6-11-9-5-3-2-4-8(9)10\/h2-6,11H,1H3

InChIKey : JBOPQACSHPPKEP-UHFFFAOYSA-N

Other name(s) : Indoxyl acetate  ||  Indoxyl-acetate  ||  1H-Indol-3-yl acetate  ||  3-Indolyl acetate  ||  SCHEMBL15553  ||  SCHEMBL3174139  ||  CHEBI:169991


MW : 175.18

Formula : C10H9NO2

CAS_number : 608-08-2

PubChem : 11841

UniChem : JBOPQACSHPPKEP-UHFFFAOYSA-N

Target

Structures : No structure

Families : ACHE, Carb_B_Chordata

References (18)

Title : A Butyrylcholinesterase Camera Biosensor Tested for Carbofuran and Paraoxon Assay - Pohanka_2022_Int.J.Anal.Chem_2022_2623155
Author(s) : Pohanka M , Zakova J
Ref : Int J Analytical Chemistry , 2022 :2623155 , 2022
Abstract :
PubMedSearch : Pohanka_2022_Int.J.Anal.Chem_2022_2623155
PubMedID: 35432544

Title : A Smartphone Camera Colorimetric Assay of Acetylcholinesterase and Butyrylcholinesterase Activity - Pohanka_2021_Sensors.(Basel)_21_
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Ref : Sensors (Basel) , 21 : , 2021
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PubMedSearch : Pohanka_2021_Sensors.(Basel)_21_
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Title : Acetylcholinesterase-catalyzed silver deposition for ultrasensitive electrochemical biosensing of organophosphorus pesticides - Liu_2020_Analyst__
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PubMedSearch : Liu_2020_Analyst__
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Title : Indoxyl Acetate as a Substrate for Analysis of Lipase Activity - Valek_2019_Int.J.Anal.Chem_2019_8538340
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Abstract :
PubMedSearch : Valek_2019_Int.J.Anal.Chem_2019_8538340
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Gene_locus related to this paper: pig-PLE1

Title : Heterologous expression, purification and characterization of three novel esterases secreted by the lignocellulolytic fungus Penicillium purpurogenum when grown on sugar beet pulp - Oleas_2017_Carbohydr.Res_443-444_42
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Abstract :
PubMedSearch : Oleas_2017_Carbohydr.Res_443-444_42
PubMedID: 28342968
Gene_locus related to this paper: talpu-a0a0f7kmg2

Title : Paper-based acetylcholinesterase inhibition assay combining a wet system for organophosphate and carbamate pesticides detection - Apilux_2015_EXCLI.J_14_307
Author(s) : Apilux A , Isarankura-Na-Ayudhya C , Tantimongcolwat T , Prachayasittikul V
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Title : Preparation and performance of a colorimetric biosensor using acetylcholinesterase and indoxylacetate for assay of nerve agents and drugs - Pohanka_2014_Interdiscip.Toxicol_7_215
Author(s) : Pohanka M , Vlcek V
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PubMedSearch : Pohanka_2014_Interdiscip.Toxicol_7_215
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Title : Pullulan encapsulation of labile biomolecules to give stable bioassay tablets - Jahanshahi-Anbuhi_2014_Angew.Chem.Int.Ed.Engl_53_6155
Author(s) : Jahanshahi-Anbuhi S , Pennings K , Leung V , Liu M , Carrasquilla C , Kannan B , Li Y , Pelton R , Brennan JD , Filipe CD
Ref : Angew Chem Int Ed Engl , 53 :6155 , 2014
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Title : Spectrophotometric methods based on 2,6-dichloroindophenol acetate and indoxylacetate for butyrylcholinesterase activity assay in plasma - Pohanka_2013_Talanta_106_281
Author(s) : Pohanka M , Drtinova L
Ref : Talanta , 106 :281 , 2013
Abstract :
PubMedSearch : Pohanka_2013_Talanta_106_281
PubMedID: 23598128

Title : Chromogenic platform based on recombinant Drosophila melanogaster acetylcholinesterase for visible unidirectional assay of organophosphate and carbamate insecticide residues - Han_2012_Anal.Chim.Acta_720_126
Author(s) : Han Z , Chi C , Bai B , Liu G , Rao Q , Peng S , Liu H , Zhao Z , Zhang D , Wu A
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PubMedSearch : Han_2012_Anal.Chim.Acta_720_126
PubMedID: 22365130

Title : Creating fast flow channels in paper fluidic devices to control timing of sequential reactions - Jahanshahi-Anbuhi_2012_Lab.Chip_12_5079
Author(s) : Jahanshahi-Anbuhi S , Chavan P , Sicard C , Leung V , Hossain SM , Pelton R , Brennan JD , Filipe CD
Ref : Lab Chip , 12 :5079 , 2012
Abstract :
PubMedSearch : Jahanshahi-Anbuhi_2012_Lab.Chip_12_5079
PubMedID: 23079674

Title : Assessment of acetylcholinesterase activity using indoxylacetate and comparison with the standard Ellman's method - Pohanka_2011_Int.J.Mol.Sci_12_2631
Author(s) : Pohanka M , Hrabinova M , Kuca K , Simonato JP
Ref : Int J Mol Sci , 12 :2631 , 2011
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PubMedSearch : Pohanka_2011_Int.J.Mol.Sci_12_2631
PubMedID: 21731462

Title : High-level secretion and purification of recombinant acetylcholinesterase from human cerebral tissue in P. pastoris and identification by chromogenic reaction - Ma_2006_Appl.Microbiol.Biotechnol_72_316
Author(s) : Ma X , Tan J , Wei D , Zhu P , Sun M
Ref : Applied Microbiology & Biotechnology , 72 :316 , 2006
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PubMedSearch : Ma_2006_Appl.Microbiol.Biotechnol_72_316
PubMedID: 16397771

Title : Acetylcholinesterase assay for rapid expression screening in liquid and solid media - Villatte_2001_Biotechniques_30_81
Author(s) : Villatte F , Bachman TT , Hussein AS , Schmid RD
Ref : Biotechniques , 30 :81 , 2001
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PubMedSearch : Villatte_2001_Biotechniques_30_81
PubMedID: 11196324

Title : Genetics of a tissue esterase polymorphism (Est-6) in the rabbit (Oryctolagus cuniculus) - van Zutphen_1987_Biochem.Genet_25_335
Author(s) : Van Zutphen LF , Den Bieman MG , von Deimling O , Fox RR
Ref : Biochemical Genetics , 25 :335 , 1987
Abstract :
PubMedSearch : van Zutphen_1987_Biochem.Genet_25_335
PubMedID: 3619880

Title : Esterase-16 (es-16): characterization, polymorphism, and linkage to chromosome 3 of a kidney esterase locus of the house mouse - von Deimling_1981_Biochem.Genet_19_1091
Author(s) : von Deimling OH , Schupp P , Otto J
Ref : Biochemical Genetics , 19 :1091 , 1981
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PubMedSearch : von Deimling_1981_Biochem.Genet_19_1091
PubMedID: 7337689

Title : Thin layer chromatography of parathion as paraoxon with cholinesterase inhibition detection - Nanda Kumar_1976_J.Assoc.Off.Anal.Chem_59_641
Author(s) : Nanda Kumar NV , Visweswariah K , Majumder SK
Ref : J Assoc Off Analytical Chemistry , 59 :641 , 1976
Abstract :
PubMedSearch : Nanda Kumar_1976_J.Assoc.Off.Anal.Chem_59_641
PubMedID: 1270394

Title : Resorufin butyrate and indoxyl acetate as fluorogenic substrates for cholinesterase -
Author(s) : Guilbault GG , Kramer DN
Ref : Analytical Chemistry , 37 :120 , 1965
PubMedID: 14230702