Sivelestat
General
Type : Peptide, Drug, Not A\/B H target, Pro-Drug, Sulfur Compound, Sulfonamide
Chemical_Nomenclature : 2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetic acid
Canonical SMILES : CC(C)(C)C(=O)OC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC=C2C(=O)NCC(=O)O
InChI : InChI=1S\/C20H22N2O7S\/c1-20(2,3)19(26)29-13-8-10-14(11-9-13)30(27,28)22-16-7-5-4-6-15(16)18(25)21-12-17(23)24\/h4-11,22H,12H2,1-3H3,(H,21,25)(H,23,24)
InChIKey : BTGNGJJLZOIYID-UHFFFAOYSA-N
Other name(s) : Ono-5046 || Unk-2Abz-Gly-OH || CHEMBL76688 || CHEBI:135704
MW : 434.5
Formula : C20H22N2O7S
CAS_number : 127373-66-4, 331731-18-1
PubChem : 107706
UniChem : BTGNGJJLZOIYID-UHFFFAOYSA-N
Target
Structures : No structure
Families : Carb_B_Chordata
References (1)
| Title : Hydrolytic profile for ester- or amide-linkage by carboxylesterases pI 5.3 and 4.5 from human liver - Takai_1997_Biol.Pharm.Bull_20_869 |
| Author(s) : Takai S , Matsuda A , Usami Y , Adachi T , Sugiyama T , Katagiri Y , Tatematsu M , Hirano K |
| Ref : Biol Pharm Bull , 20 :869 , 1997 |
| Abstract : |
| PubMedSearch : Takai_1997_Biol.Pharm.Bull_20_869 |
| PubMedID: 9300133 |
| Gene_locus related to this paper: human-CES1 , human-CES2 |