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Substrate Report for: NAPE

this is only one representative of NAPEs which can bear different fatty acid chains


General
Type Phospholipid, Phosphoethanolamine
Chemical_Nomenclature [(2R)-3-[hydroxy-[2-[[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]amino]ethoxy]phosphoryl]oxy-2-[(Z)-octadec-9-enoyl]oxypropyl] (Z)-octadec-9-enoate
Canonical SMILES CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)CCCC=CCC=CCC=CCC=CCCCCC)OC(=O)CCCCCCCC=CCCCCCCCC
InChI InChI=1S/C61H108NO9P/c1-4-7-10-13-16-19-22-25-28-29-32-33-36-39-42-45-48-51-59(63)62-54-55-69-72(66,67)70-57-58(71-61(65)53-50-47-44-41-38-35-31-27-24-21-18-15-12-9-6-3)56-68-60(64)52-49-46-43-40-37-34-30-26-23-20-17-14-11-8-5-2/h16,19,25-28,30-33,39,42,58H,4-15,17-18,20-24,29,34-38,40-41,43-57H2,1-3H3,(H,62,63)(H,66,67)/b19-16-,28-25-,30-26-,31-27-,33-32-,42-39-/t58-/m1/s1
InChIKey WDNUSSOPDWPIPF-ANDZTLMQSA-N
Other name(s) N-arachidonoyl-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine ; CHEBI:85784 ; Q27158716 ; 1,2-dioleoyl-sn-glycero-3-phospho(N-arachidonoyl)ethanolamine ; (2R,14Z,17Z,20Z,23Z)-5-hydroxy-2-{[(9Z)-octadec-9-enoyl]oxy}-5,10-dioxo-4,6-dioxa-9-aza-5lambda(5)-phosphanonacosa-14,17,20,23-tetraen-1-yl (9Z)-octadec-9-enoate
________________________________________________________________________________________________
MW|1030.5
Formula|C61H108NO9P
CAS_number|
PubChem|91666421
UniChem|WDNUSSOPDWPIPF-ANDZTLMQSA-N
IUPHAR|
Wikipedia|

Target
Families | NAPE ligand of proteins in family: CGI-58_ABHD5_ABHD4
Protein | human-ABHD4

References:
Search PubMed for references concerning: NAPE

1 more
    Title: Selective N-Hydroxyhydantoin Carbamate Inhibitors of Mammalian Serine Hydrolases
    Cognetta AB, 3rd, Niphakis MJ, Lee HC, Martini ML, Hulce JJ, Cravatt BF
    Ref: Chemical Biology, 22:928, 2015 : PubMed

            

    Title: ABHD4 regulates multiple classes of N-acyl phospholipids in the mammalian central nervous system
    Lee HC, Simon GM, Cravatt BF
    Ref: Biochemistry, 54:2539, 2015 : PubMed

            

    Title: Lipid profiling reveals tissue-specific differences for ethanolamide lipids in mice lacking fatty acid amide hydrolase
    Kilaru A, Isaac G, Tamura P, Baxter D, Duncan SR, Venables BJ, Welti R, Koulen P, Chapman KD
    Ref: Lipids, 45:863, 2010 : PubMed