Simon GM

References (13)

Title : ABHD4-dependent developmental anoikis safeguards the embryonic brain - Laszlo_2020_Nat.Commun_11_4363
Author(s) : Laszlo ZI , Lele Z , Zoldi M , Miczan V , Mogor F , Simon GM , Mackie K , Kacskovics I , Cravatt BF , Katona I
Ref : Nat Commun , 11 :4363 , 2020
PubMedID: 32868797
Gene_locus related to this paper: human-ABHD4 , mouse-abhd4

Title : Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan - Chen_2019_Nat.Chem.Biol_15_453
Author(s) : Chen AL , Lum KM , Lara-Gonzalez P , Ogasawara D , Cognetta AB, 3rd , To A , Parsons WH , Simon GM , Desai A , Petrascheck M , Bar-Peled L , Cravatt BF
Ref : Nat Chemical Biology , 15 :453 , 2019
PubMedID: 30911178

Title : Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators - Clapper_2018_J.Pharmacol.Exp.Ther_367_494
Author(s) : Clapper JR , Henry CL , Niphakis MJ , Knize AM , Coppola AR , Simon GM , Ngo N , Herbst RA , Herbst DM , Reed AW , Cisar JS , Weber OD , Viader A , Alexander JP , Cunningham ML , Jones TK , Fraser IP , Grice CA , Ezekowitz RAB , O'Neill GP , Blankman JL
Ref : Journal of Pharmacology & Experimental Therapeutics , 367 :494 , 2018
PubMedID: 30305428

Title : Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders - Cisar_2018_J.Med.Chem_61_9062
Author(s) : Cisar JS , Weber OD , Clapper JR , Blankman JL , Henry CL , Simon GM , Alexander JP , Jones TK , Ezekowitz RAB , O'Neill GP , Grice CA
Ref : Journal of Medicinal Chemistry , 61 :9062 , 2018
PubMedID: 30067909

Title : ABHD4 regulates multiple classes of N-acyl phospholipids in the mammalian central nervous system - Lee_2015_Biochemistry_54_2539
Author(s) : Lee HC , Simon GM , Cravatt BF
Ref : Biochemistry , 54 :2539 , 2015
PubMedID: 25853435
Gene_locus related to this paper: human-ABHD4

Title : Bacteria from diverse habitats colonize and compete in the mouse gut - Seedorf_2014_Cell_159_253
Author(s) : Seedorf H , Griffin NW , Ridaura VK , Reyes A , Cheng J , Rey FE , Smith MI , Simon GM , Scheffrahn RH , Woebken D , Spormann AM , Van Treuren W , Ursell LK , Pirrung M , Robbins-Pianka A , Cantarel BL , Lombard V , Henrissat B , Knight R , Gordon JI
Ref : Cell , 159 :253 , 2014
PubMedID: 25284151
Gene_locus related to this paper: 9firm-a0a0j1g143

Title : Monoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome - Lysenko_2014_PLoS.One_9_e114521
Author(s) : Lysenko LV , Kim J , Henry C , Tyrtyshnaia A , Kohnz RA , Madamba F , Simon GM , Kleschevnikova NE , Nomura DK , Ezekowitz RA , Kleschevnikov AM
Ref : PLoS ONE , 9 :e114521 , 2014
PubMedID: 25474204

Title : Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening - Bachovchin_2010_Proc.Natl.Acad.Sci.U.S.A_107_20941
Author(s) : Bachovchin DA , Ji T , Li W , Simon GM , Blankman JL , Adibekian A , Hoover H , Niessen S , Cravatt BF
Ref : Proc Natl Acad Sci U S A , 107 :20941 , 2010
PubMedID: 21084632

Title : Activity-based proteomics of enzyme superfamilies: serine hydrolases as a case study - Simon_2010_J.Biol.Chem_285_11051
Author(s) : Simon GM , Cravatt BF
Ref : Journal of Biological Chemistry , 285 :11051 , 2010
PubMedID: 20147750

Title : Activation of the endocannabinoid system by organophosphorus nerve agents - Nomura_2008_Nat.Chem.Biol_4_373
Author(s) : Nomura DK , Blankman JL , Simon GM , Fujioka K , Issa RS , Ward AM , Cravatt BF , Casida JE
Ref : Nat Chemical Biology , 4 :373 , 2008
PubMedID: 18438404

Title : Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain - Simon_2008_J.Biol.Chem_283_9341
Author(s) : Simon GM , Cravatt BF
Ref : Journal of Biological Chemistry , 283 :9341 , 2008
PubMedID: 18227059

Title : A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol - Blankman_2007_Chem.Biol_14_1347
Author(s) : Blankman JL , Simon GM , Cravatt BF
Ref : Chemical Biology , 14 :1347 , 2007
PubMedID: 18096503
Gene_locus related to this paper: human-ABHD6 , human-ABHD12 , human-MGLL

Title : Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha\/beta-hydrolase 4 in this pathway - Simon_2006_J.Biol.Chem_281_26465
Author(s) : Simon GM , Cravatt BF
Ref : Journal of Biological Chemistry , 281 :26465 , 2006
PubMedID: 16818490
Gene_locus related to this paper: human-ABHD4