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Substrate Report for: dMUP

Substrate for testing OP-hydrolase activity


General
Type Organophosphate, Coumarin
Chemical_Nomenclature dimethyl (4-methyl-2-oxochromen-7-yl) phosphate
Canonical SMILES CC1=CC(=O)OC2=C1C=CC(=C2)OP(=O)(OC)OC
InChI InChI=1S/C12H13O6P/c1-8-6-12(13)17-11-7-9(4-5-10(8)11)18-19(14,15-2)16-3/h4-7H,1-3H3
InChIKey SVVSCEWVQSATRC-UHFFFAOYSA-N
Other name(s) dimethyl 4-methylumbelliferyl phosphate ; O,O-dimehtyl 4-methylumbelliferyl phosphate ; SCHEMBL1023154
________________________________________________________________________________________________
MW|284.20
Formula|C12H13O6P
CAS_number|
PubChem|60108029
UniChem|SVVSCEWVQSATRC-UHFFFAOYSA-N
IUPHAR|
Wikipedia|

Target
Families | dMUP ligand of proteins in family: Carb_B_Arthropoda

References:
Search PubMed for references concerning: dMUP
    Title: Hydrolysis of organophosphorus insecticides by in vitro modified carboxylesterase E3 from Lucilia cuprina
    Heidari R, Devonshire AL, Campbell BE, Bell KL, Dorrian SJ, Oakeshott JG, Russell RJ
    Ref: Insect Biochemistry & Molecular Biology, 34:353, 2004 : PubMed

            

    Title: Kinetic efficiency of mutant carboxylesterases implicated in organophosphate insecticide resistance
    Devonshire AL, Heidari R, Bell KL, Campbell PM, Campbell BE, Odgers WA, Oakeshott JG, Russell RJ
    Ref: Pesticide Biochemistry and Physiology, 76:1, 2003 : PubMed